Boston Children's Hospital

Running trials

• Not yet recruiting

  Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients

  NCT06397781· Phase 4· Boston Children's Hospital· Source

• Not yet recruiting

  Feasibility Trial of a Parent Peer-Co-Led Caregiver Group for Pediatric Early Onset Schizophrenia Spectrum Disorders

  NCT07867964· Boston Children's Hospital· Source

• Not yet recruiting

  Academic Detailing to Optimize PrEP Implementation in Pediatric Primary Care Settings: ADOPT-PrEP

  NCT06804382· Boston Children's Hospital· Source

• Not yet recruiting

  Buprenorphine for the Management of Pain in Children With Sickle Cell Disease

  NCT07799571· Phase 1· Natasha Archer· Source

• Not yet recruiting

  Validation of the Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) for Adolescents

  NCT07532109· Boston Children's Hospital· Source

• Not yet recruiting

  COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

  NCT07281027· Phase 3· Yale University· Source

• Recruiting

  A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymph...

  NCT05621291· National Cancer Institute (NCI)· Source

• Not yet recruiting

  IMPACT-Ready Study

  NCT07931690· Coalition for Aligning Science· Source

• Recruiting

  Pediatric Longitudinal Glomerular Disease: a PNRC Multi-Institutional Cohort Study

  NCT07931170· Pediatric Nephrology Research Consortium· Source

• Not yet recruiting

  BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease

  NCT07729995· Phase 1· Luminary Therapeutics· Source

• Recruiting

  Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)

  NCT07817875· Phase 3· Eli Lilly and Company· Source

• Not yet recruiting

  Rethinking Early Airway Clearence Therapies

  NCT07696338· Nicole Hamblett· Source

• Not yet recruiting

  Pedi-STAR: Surface Target Antibody-drug Conjugate (ADC) Antigen Expression in Relapsed/Refractory Pediatric Solid and CNS Tumors

  NCT07793994· Dana-Farber Cancer Institute· Source

• Not yet recruiting

  Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

  NCT07218575· Phase 2/3· Boston Children's Hospital· Source

• Recruiting

  B7-H3.CD28Z.CART in CNS Neoplasms

  NCT07390539· Phase 1· Robbie Majzner· Source

• Recruiting

  Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness

  NCT07374640· Early phase 1· Boston Children's Hospital· Source

• Not yet recruiting

  Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics

  NCT07706140· Boston Children's Hospital· Source

• Recruiting

  Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention

  NCT07662239· Dana-Farber Cancer Institute· Source

• Recruiting

  Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Sickle Cell Disease

  NCT07708350· Phase 1· Daniel Bauer· Source

• Recruiting

  BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease

  NCT07582848· Carelon Research· Source

• Recruiting

  Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)

  NCT07582861· Carelon Research· Source

• Recruiting

  Study of Cabozantinib With Selumetinib for Plexiform Neurofibromas

  NCT06502171· Phase 1· Girish Dhall, MD· Source

• Recruiting

  A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

  NCT07192952· Phase 3· Bayer· Source

• Not yet recruiting

  An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function

  NCT07613398· Matthias Stuber· Source

• Not yet recruiting

  Impact of a Produce Prescription Program and Nutrition Education Intervention on Cardiovascular Health in Youth

  NCT07545005· Boston Children's Hospital· Source

• Not yet recruiting

  The Association Between Tau & GFAP and Postoperative Neurological Impairment in Patients Undergoing Cardiac Surgery

  NCT06899971· Boston Children's Hospital· Source

• Recruiting

  A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study

  NCT07525843· Carelon Research· Source

• Recruiting

  A Study to Evaluate the Long-term Safety and Tolerability of Xanomeline and Trospium Chloride for the Treatment of Psychiatric Disorders in Children and Adolescents

  NCT07424404· Phase 3· Karuna Therapeutics, Inc., a Bristol Myers Squibb company· Source

• Recruiting

  Piloting the Competence in Romance and Understanding Sexual Health Curriculum

  NCT07406100· Boston Children's Hospital· Source

• Not yet recruiting

  Evaluation of a Point-of-care Lateral Flow Assay in Glial Fibrillary Acidic Protein (GFAP) and D-dimer in Diagnosis of Large Vessel Occlusion Acute Ischemic Stroke in a Pediatric Hospital

  NCT07474675· Boston Children's Hospital· Source

• Recruiting

  A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

  NCT07148089· Phase 1· Solid Biosciences Inc.· Source

• Recruiting

  CF Wellness Program

  NCT07071324· Johns Hopkins University· Source

• Not yet recruiting

  Optimal Timing of Ketamine Initiation for SCD Pain

  NCT07450430· Phase 3· Boston Children's Hospital· Source

• Recruiting

  A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Schizophrenia in Adolescents (EMERGENT TEEN)

  NCT07288567· Phase 3· Bristol-Myers Squibb· Source

• Recruiting

  Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study

  NCT07114718· Starlight Cardiovascular Inc· Source

• Enrolling by invitation

  Assessing Post-operative Outcomes After Children's Sistrunk Procedure With or Without a Drain

  NCT07148895· University of Rochester· Source

• Recruiting

  A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

  NCT07287982· Phase 2· argenx· Source

• Recruiting

  A Long-term Follow-up Study in Patients Who Received BEAM-101

  NCT07373639· Beam Therapeutics Inc.· Source

• Recruiting

  Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies

  NCT06647979· Phase 1· Daniel Bauer· Source

• Recruiting

  A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

  NCT07227857· Phase 1/2· Institut de Recherches Internationales Servier· Source

• Recruiting

  A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

  NCT07188805· Phase 3· Bayer· Source

• Recruiting

  Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

  NCT06555939· Boston Children's Hospital· Source

• Recruiting

  A Study Evaluating the Real-World Experience of Givinostat in Patients With Duchenne Muscular Dystrophy

  NCT07127978· ITF Therapeutics LLC· Source

• Recruiting

  Clinical Course Of Disease In Participants With FA-CM

  NCT06865482· Lexeo Therapeutics· Source

• Recruiting

  A Trial of Setmelanotide in Patients With Congenital Hypothalamic Obesity (Sub-study of NCT05774756)

  NCT06760546· Phase 3· Rhythm Pharmaceuticals, Inc.· Source

• Recruiting

  Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG)

  NCT05944692· CREmedical· Source

• Recruiting

  Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

  NCT06188741· Phase 2· University of Alabama at Birmingham· Source

• Recruiting

  A Study of Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

  NCT07058077· Phase 2/3· Merck Sharp & Dohme LLC· Source

• Recruiting

  Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma

  NCT07027748· Phase 1· Steven DuBois, MD· Source

• Active, not recruiting

  A Double-blind Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen in Patients With Dravet Syndrome

  NCT06872125· Phase 3· Stoke Therapeutics, Inc· Source

Showing 50 of 220.

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Childhood cancers25 recruiting
• Congenital heart disease15 recruiting
• Cystic fibrosis12 recruiting
• Sickle cell disease11 recruiting
• Epilepsy8 recruiting
• Crohn's disease6 recruiting
• Duchenne muscular dystrophy5 recruiting
• Neuroblastoma5 recruiting
• Spinal muscular atrophy5 recruiting
• Autism4 recruiting
• Heart failure4 recruiting
• Lupus (SLE)4 recruiting
• Migraine4 recruiting
• Obesity4 recruiting
• Sarcoma4 recruiting
• Ulcerative colitis4 recruiting
• Acute lymphoblastic leukaemia3 recruiting
• Hearing loss3 recruiting
• High blood pressure3 recruiting
• Schizophrenia3 recruiting
• Type 1 diabetes3 recruiting
• Ventricular tachycardia3 recruiting
• Asthma2 recruiting
• Atopic dermatitis (eczema)2 recruiting
• Coeliac disease2 recruiting
• Dermatomyositis and polymyositis (myositis)2 recruiting
• Dystonia2 recruiting
• Gastroparesis2 recruiting
• HIV2 recruiting
• Retinitis pigmentosa2 recruiting
• Rheumatoid arthritis2 recruiting
• Thalassaemia2 recruiting
• Acute myeloid leukaemia1 recruiting
• Cerebral palsy1 recruiting
• Cervical cancer1 recruiting
• Chronic kidney disease1 recruiting
• Fabry disease1 recruiting
• Familial hypercholesterolaemia1 recruiting
• Friedreich ataxia1 recruiting
• Gaucher disease1 recruiting
• Haemophilia1 recruiting
• Hydrocephalus1 recruiting
• Hypertrophic cardiomyopathy1 recruiting
• IgA nephropathy1 recruiting
• Insomnia1 recruiting
• Liver and biliary tract cancer1 recruiting
• Macular degeneration1 recruiting
• Myelodysplastic syndromes1 recruiting
• Myeloproliferative neoplasms1 recruiting
• Pancreatic cancer1 recruiting
• Pompe disease1 recruiting
• Psoriasis1 recruiting
• Psoriatic arthritis1 recruiting
• Pulmonary arterial hypertension1 recruiting
• Stroke1 recruiting
• Systemic sclerosis (scleroderma)1 recruiting
• Thyroid cancer1 recruiting

Closed trials

• Withdrawn

  IUD and Norethindrone Acetate for Treatment of Endometriosis

  NCT04948489· Phase 2· Boston Children's Hospital· Source

• Completed

  Automated Inhaler Monitoring for Asthma Medication Usage

  NCT06825871· Boston Children's Hospital· Source

• Completed

  OnTrackCF: Engagement, Feasibility, and Acceptability Study

  NCT07031323· Boston Children's Hospital· Source

• Completed

  Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta

  NCT07108153· Phase 2· Sionna Therapeutics Inc.· Source

• Withdrawn

  TENS for Endometriosis Pain in Adolescents and Young Adults

  NCT06914752· Boston Children's Hospital· Source

• Completed

  Pediatric Adhesion and New Dermal Approach Study

  NCT07118124· iRhythm Technologies, Inc.· Source

• Terminated

  Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

  NCT06700811· Phase 1· Heather Olson· Source

• Completed

  Description of Patients With Type 1 Diabetes Treated With Teplizumab

  NCT06892002· Sanofi· Source

• Terminated

  Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)

  NCT06042257· Phase 2· Rachel G. Greenberg, MD, MB, MHS· Source

• Completed

  ABC-CT Pre-School Feasibility Study

  NCT06413316· Yale University· Source

• Withdrawn

  Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations

  NCT06080165· Phase 1/2· Stanford University· Source

• Completed

  A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis

  NCT06159725· Phase 1/2· Clarametyx Biosciences, Inc.· Source

• Completed

  The PediQUEST Response to Pain Of Children With Neurologic Disability Pilot Randomized Controlled Trial

  NCT06075797· Massachusetts General Hospital· Source

• Completed

  Biomarkers Research in Anxiety for Validation and Efficacy

  NCT06221176· Boston Children's Hospital· Source

• Completed

  Improving Social Relationships for Adolescents With Central Disorders of Hypersomnolence

  NCT06251063· Boston Children's Hospital· Source

• Withdrawn

  Study of a Gene Therapy Treatment for Hemophilia A

  NCT06297486· Phase 3· Spark Therapeutics, Inc.· Source

• Completed

  Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis

  NCT06154447· Phase 1· Vertex Pharmaceuticals Incorporated· Source

• Completed

  Insomnia Prevention in Children With Acute Lymphoblastic Leukemia

  NCT05866887· Dana-Farber Cancer Institute· Source

• Completed

  Phase 1 Study to Assess Safety and Efficacy of ANG003

  NCT06052293· Phase 1· Anagram Therapeutics, Inc.· Source

• Completed

  First CRUSH: Piloting the Preliminary Feasibility and Acceptability of the Competence in Romance and Understanding Sexual Health (CRUSH) Curriculum

  NCT05910658· Boston Children's Hospital· Source

• Completed

  Oral Ketamine for Treatment of Vaso-Occlusive Pain

  NCT05378555· Phase 1· Boston Children's Hospital· Source

• Recruiting

  A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

  NCT05442567· Phase 3· Takeda· Source

• Completed

  A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)

  NCT05668741· Phase 1/2· Vertex Pharmaceuticals Incorporated· Source

• Completed

  PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS

  NCT05296096· Boston Children's Hospital· Source

• Completed

  Intervening in Food Insecurity to Reduce and Mitigate (InFoRM) Childhood Obesity

  NCT05586269· Boston Children's Hospital· Source

• Completed

  Ecopipam Tablets to Study Tourette's Disorder in Children, Adolescents and Adults

  NCT05615220· Phase 3· Emalex Biosciences Inc.· Source

• Terminated

  A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)

  NCT05600426· Phase 3· Boston Children's Hospital· Source

• Completed

  Investigating the Impact of JASPER Behavioral Therapy in Children With Down Syndrome

  NCT05638412· Boston Children's Hospital· Source

• Completed

  Observational Study Comparing Home to Office Spirometry

  NCT05285410· Chris Goss· Source

• Completed

  Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin Analysis

  NCT05436535· Phase 4· National Institute of Allergy and Infectious Diseases (NIAID)· Source

• Completed

  Study to Assess Safety and Efficacy of Tenapanor for Treatment of IBS-C in Pediatric Patients 12 to Less Than 18 Years

  NCT05643534· Phase 3· Ardelyx· Source

• Recruiting

  A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

  NCT05457283· Phase 3· Bayer· Source

• Completed

  Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes

  NCT05491499· Boston Children's Hospital· Source

• Terminated

  Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation for AML

  NCT05569512· Phase 1· Malika Kapadia· Source

• Completed

  A Study of Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile Psoriatic Arthritis

  NCT05083182· Phase 3· Janssen Research & Development, LLC· Source

• Completed

  Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension

  NCT04039464· Phase 3· Johns Hopkins University· Source

• Completed

  Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infection

  NCT05010577· Phase 1/2· BiomX, Inc.· Source

• Completed

  Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS)

  NCT05312177· Carelon Research· Source

• Completed

  Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

  NCT04965597· Phase 2· Fred Hutchinson Cancer Center· Source

• Completed

  Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam

  NCT05156320· Phase 3· Scholar Rock, Inc.· Source

• Completed

  The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study

  NCT05294705· Yale University· Source

• Completed

  Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients

  NCT05255445· Westat· Source

• Completed

  Basimglurant (NOE-101) in Children, Adolescents, and Young Adults With TSC

  NCT05059327· Phase 2· Noema Pharma AG· Source

• Terminated

  Use of Tirosint®-SOL or Tablet Formulations of Levothyroxine in Pediatric Patients With Congenital Hypothyroidism (CH)

  NCT05228184· Phase 4· IBSA Institut Biochimique SA· Source

• Completed

  Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older

  NCT05153317· Phase 3· Vertex Pharmaceuticals Incorporated· Source

• Terminated

  AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department

  NCT04669288· Phase 3· University of Arizona· Source

• Completed

  A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)

  NCT05096221· Phase 3· Sarepta Therapeutics, Inc.· Source

• Completed

  A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation

  NCT05076149· Phase 3· Vertex Pharmaceuticals Incorporated· Source

• Completed

  A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Ulcerative Colitis (UC)

  NCT04779307· Phase 3· Takeda· Source

• Completed

  Auditory Neural Function in Implanted Patients With Usher Syndrome

  NCT04906135· Ohio State University· Source

Showing 50 of 100.

Conditions

Diseases this institution publishes on or runs trials for.

• Epilepsy148 works · 15 trials
• Congenital heart disease125 works · 28 trials
• Asthma81 works · 11 trials
• Autism78 works · 14 trials
• Cystic fibrosis58 works · 29 trials
• Childhood cancers46 works · 56 trials
• Type 1 diabetes34 works · 4 trials
• Sickle cell disease33 works · 19 trials
• Hydrocephalus29 works · 1 trial
• Glaucoma28 works · 0 trials
• Dystonia25 works · 2 trials
• Acute lymphoblastic leukaemia24 works · 12 trials
• Lupus (SLE)23 works · 5 trials
• Hodgkin lymphoma21 works · 0 trials
• Sarcoma20 works · 10 trials
• Narcolepsy20 works · 2 trials
• Endometriosis20 works · 5 trials
• Migraine19 works · 2 trials
• Spinal muscular atrophy19 works · 13 trials
• Obstructive sleep apnoea18 works · 1 trial
• Down syndrome17 works · 5 trials
• Duchenne muscular dystrophy16 works · 13 trials
• Neuroblastoma16 works · 8 trials
• Cerebral palsy15 works · 4 trials
• Hearing loss15 works · 4 trials
• Hypertrophic cardiomyopathy14 works · 1 trial
• Pulmonary arterial hypertension13 works · 4 trials
• Coeliac disease12 works · 3 trials
• Dilated cardiomyopathy10 works · 0 trials
• Ventricular tachycardia8 works · 3 trials