St. Michael's Hospital

Running trials

• Not yet recruiting

  An Online Tailored Cognitive Therapy-Based Intervention for Depression in Multiple Sclerosis: ACTION-MS Online

  NCT07875309· University of Melbourne· Source

• Recruiting

  A Research Study Investigating Denecimig (Mim8) in Adults With Acquired Haemophilia A

  NCT07830732· Phase 3· Novo Nordisk A/S· Source

• Recruiting

  A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

  NCT07521007· Phase 2· Beijing Inno Medicine Co., Ltd.· Source

• Recruiting

  Lumacaftor Yields Reversal of Impaired Cerebral Blood Flow in Heart Failure Patients

  NCT07695090· Phase 2· Qanatpharma AG· Source

• Recruiting

  Oral Versus Intramuscular Steroid Use to Control Rheumatoid Arthritis Flares

  NCT07245732· Phase 4· Sunnybrook Health Sciences Centre· Source

• Active, not recruiting

  Intravascular Neuro OCT Imaging System for Aneurysm Treatment Evaluation

  NCT07214220· Spryte Medical· Source

• Recruiting

  Pivotal Study of the Silk Vista Baby Flow Diverters in the Treatment of Unruptured Intracranial Aneurysms (PIONEER)

  NCT07225075· Balt USA· Source

• Not yet recruiting

  Sustained Mood Improvement With Laughing Gas Exposure

  NCT07262008· Phase 3· Women's College Hospital· Source

• Recruiting

  Integrated Suicide & Trauma Therapy for Suicide Risk

  NCT05613972· Unity Health Toronto· Source

• Active, not recruiting

  A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

  NCT07170150· Phase 3· Hoffmann-La Roche· Source

• Recruiting

  Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)

  NCT07059962· Bodyport Inc.· Source

• Recruiting

  EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

  NCT07064473· Phase 3· Boehringer Ingelheim· Source

• Active, not recruiting

  P1101 in Treating Patients With Early PMF or Overt PMF at Low or Intermediate-1 Risk

  NCT06468033· Phase 3· PharmaEssentia· Source

• Recruiting

  Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

  NCT07177352· Phase 3· Hoffmann-La Roche· Source

• Recruiting

  A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

  NCT06979362· Phase 2· Novo Nordisk A/S· Source

• Recruiting

  Shorter and Safer Treatment Regimens for Latent TB

  NCT06498414· Phase 2/3· McGill University Health Centre/Research Institute of the McGill University Health Centre· Source

• Recruiting

  ANCHOR Study: A Study to Assess the Safety and Efficacy of ABBV-CLS-628 in Adult Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

  NCT06902558· Phase 2· Calico Life Sciences LLC· Source

• Recruiting

  A Study of Transcatheter Aortic Valve Replacement Case Selection and Valve Sizing Using the ABC Bicuspid Sizing Algorithm

  NCT06991517· World Health Research Inc.· Source

• Recruiting

  Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

  NCT06563895· Phase 3· Eidos Therapeutics, a BridgeBio company· Source

• Recruiting

  COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

  NCT06809998· Phase 1/2· Unity Health Toronto· Source

• Recruiting

  Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive Impairment

  NCT06780917· Centre for Addiction and Mental Health· Source

• Not yet recruiting

  Implementation of Online Mindfulness-Based Stress Reduction Tailored for People with Multiple Sclerosis

  NCT06415552· Robert Simpson· Source

• Recruiting

  Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

  NCT06736574· Phase 3· Cytokinetics· Source

• Active, not recruiting

  Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

  NCT06498960· CereVasc Inc· Source

• Active, not recruiting

  Evaluation of a Simple-Prep Controlled Embolic

  NCT06453642· Fluidx Medical Technology, Inc.· Source

• Recruiting

  Pericardiotomy in Cardiac Surgery

  NCT06486636· Population Health Research Institute· Source

• Recruiting

  ACT-GLOBAL THROMBOLYSIS (ACT-WHEN-001) Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632

  NCT06320431· Phase 3· University of Calgary· Source

• Recruiting

  CRS Questionnaire Validation Project

  NCT06970977· The European Forum for Research and Education in Allergy and Airway Diseases· Source

• Active, not recruiting

  EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

  NCT06531824· Phase 3· Boehringer Ingelheim· Source

• Recruiting

  Short Term Anti-aRrhythmic Therapy for Post-Operative AF in Cardiac Surgery Patients Pilot Trial

  NCT05841056· Phase 3· Population Health Research Institute· Source

• Recruiting

  Fixed Duration vs Continuous Anti-CD38 Antibody Therapy Among Transplant Ineligible Older Adults With Newly-Diagnosed Multiple Myeloma

  NCT06182774· Phase 3· Canadian Cancer Trials Group· Source

• Enrolling by invitation

  ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

  NCT05932615· Abbott Medical Devices· Source

• Recruiting

  The STOP-MED CTRCD Trial

  NCT06183437· Phase 4· Dinesh Thavendiranathan· Source

• Active, not recruiting

  Take-home Functional Electrical Stimulation for MDD

  NCT06261177· Unity Health Toronto· Source

• Active, not recruiting

  Phosphatase Inhibition by Intracoronary Gene Therapy in Subjects With Non-Ischemic NYHA Class III Heart Failure

  NCT05598333· Phase 2· AskBio Inc· Source

• Active, not recruiting

  A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

  NCT05968326· Phase 2· Genentech, Inc.· Source

• Recruiting

  International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

  NCT06174727· Montefiore Medical Center· Source

• Active, not recruiting

  MS-DETECT: Early Detection of Multiple Sclerosis Progression With MSCopilot® Detect

  NCT05816122· Ad scientiam· Source

• Recruiting

  A Study of Reduced Dosing of the Nonavalent HPV Vaccine in Women Living With HIV

  NCT05495906· Phase 4· University of British Columbia· Source

• Recruiting

  TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer

  NCT05582772· University Health Network, Toronto· Source

• Active, not recruiting

  Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD

  NCT05711940· Phase 3· COMPASS Pathways· Source

• Active, not recruiting

  Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

  NCT05478304· AtriCure, Inc.· Source

• Recruiting

  COLchicine and Non-enteric Coated Aspirin in the Cardiovascular Outcomes Trial of Patients With Type 2 Diabetes

  NCT05633810· Phase 3· Montreal Heart Institute· Source

• Active, not recruiting

  A Study to Assess Efficacy, Safety, and Tolerability of P1101 in Adult Patients With PV

  NCT05481151· Phase 3· PharmaEssentia· Source

• Recruiting

  Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

  NCT05174169· Phase 2/3· NRG Oncology· Source

• Recruiting

  Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

  NCT05298124· Ottawa Heart Institute Research Corporation· Source

• Enrolling by invitation

  Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

  NCT04451044· Philips Clinical & Medical Affairs Global· Source

• Recruiting

  Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

  NCT04634240· University of British Columbia· Source

• Active, not recruiting

  A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis

  NCT04544449· Phase 3· Hoffmann-La Roche· Source

• Recruiting

  Evaluating Oral Peri-operative Acetylsalicylic Acid in Subjects Undergoing Endovascular Coiling-only of Unruptured Brain Aneurysms

  NCT04192955· Phase 3· University of Calgary· Source

Showing 50 of 80.

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Heart failure5 recruiting
• Aortic stenosis3 recruiting
• Brain aneurysm3 recruiting
• Chronic kidney disease3 recruiting
• Coronary artery disease3 recruiting
• Depression3 recruiting
• Atrial fibrillation2 recruiting
• High blood pressure2 recruiting
• Multiple sclerosis2 recruiting
• Type 2 diabetes2 recruiting
• Amyloidosis1 recruiting
• Aortic aneurysm1 recruiting
• Chronic rhinosinusitis with nasal polyps1 recruiting
• Colorectal cancer1 recruiting
• COPD1 recruiting
• Haemophilia1 recruiting
• HIV1 recruiting
• Mild cognitive impairment1 recruiting
• Multiple myeloma1 recruiting
• Obesity1 recruiting
• Osteoarthritis1 recruiting
• Osteoporosis1 recruiting
• Polycystic kidney disease1 recruiting
• Prostate cancer1 recruiting
• Rheumatoid arthritis1 recruiting
• Stroke1 recruiting
• Tuberculosis1 recruiting

Closed trials

• Completed

  Incomplete Cervical SCI Without Instability

  NCT05653206· AO Foundation, AO Spine· Source

• Completed

  Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial

  NCT06028126· Unity Health Toronto· Source

• Completed

  Musical Attention Control and Executive Function Training for Adults With MDD

  NCT05694156· Unity Health Toronto· Source

• Completed

  Cannabinoids vs. Placebo on Persistent Post-surgical Pain Following TKA: A Pilot RCT

  NCT03825965· Phase 3· McMaster University· Source

• Completed

  A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)

  NCT05841030· Janssen Research & Development, LLC· Source

• Completed

  Neuro RX Gamma for Amnestic Mild Cognitive Impairment (aMCI)

  NCT05563298· Early phase 1· Unity Health Toronto· Source

• Completed

  SMILE Trial - Imaging Sub-Study

  NCT05528718· Unity Health Toronto· Source

• Completed

  Personalized Smoking Cessation Infographic in COPD

  NCT04119934· Unity Health Toronto· Source

• Completed

  A Biomarker-Guided, Randomized, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With TRD

  NCT05113771· Phase 2· Denovo Biopharma LLC· Source

• Completed

  Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial

  NCT04957368· Phase 4· Unity Health Toronto· Source

• Completed

  A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation

  NCT05076149· Phase 3· Vertex Pharmaceuticals Incorporated· Source

• Completed

  Near Patient Study of the OraQuick ADVANCE® HIV-1/2 Rapid Antibody Test in Oral Fluid and Fingerstick Whole Blood

  NCT04810559· Unity Health Toronto· Source

• Completed

  A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)

  NCT04777409· Phase 3· Novo Nordisk A/S· Source

• Recruiting

  Nabilone for Agitation Blinded Intervention Trial

  NCT04516057· Phase 3· Sunnybrook Health Sciences Centre· Source

• Completed

  Scaling Up Maternal Mental Healthcare by Increasing Access to Treatment (SUMMIT)

  NCT04153864· Mount Sinai Hospital, Canada· Source

• Completed

  Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea

  NCT03964376· University Health Network, Toronto· Source

• Recruiting

  Evaluation of Stool Based Markers for the Early Detection of Colorectal Cancers and Adenomas

  NCT00843375· University of Michigan Rogel Cancer Center· Source

• Completed

  A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes

  NCT03914326· Phase 3· Novo Nordisk A/S· Source

• Completed

  (PATHFINDER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, in Patients With Advanced Systemic Mastocytosis

  NCT03580655· Phase 2· Blueprint Medicines Corporation· Source

• Completed

  A Study to Evaluate Prospective Efficacy and Safety Data of Current FIX Prophylaxis Replacement Therapy in Adult Hemophilia B Subjects (FIX:C≤2%) or Current FVIII Prophylaxis Replacement Therapy in Adult Hemophilia A Subjects (FVIII:C≤1%)

  NCT03587116· Phase 3· Pfizer· Source

• Completed

  Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome

  NCT03473223· Phase 3· CSL Behring· Source

• Completed

  Colchicine and Spironolactone in Patients with MI / SYNERGY Stent Registry

  NCT03048825· Phase 3· Population Health Research Institute· Source

• Completed

  PIONEER III Trial to Assess Safety and Efficacy of the BuMA Supreme™ Drug Coated Coronary Stent in Patients With Coronary Disease

  NCT03168776· Sino Medical Sciences Technology Inc.· Source

• Completed

  Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

  NCT03020303· Phase 3· Hamilton Health Sciences Corporation· Source

• Completed

  Antiarrhythmics or Ablation for Ventricular Tachycardia 2

  NCT02830360· Phase 4· John Sapp· Source

• Completed

  Optimal Anticoagulation for Higher Risk Patients Post-Catheter Ablation for Atrial Fibrillation Trial

  NCT02168829· Phase 4· Ottawa Heart Institute Research Corporation· Source

• Completed

  SPYRAL HTN-ON MED Study of Renal Denervation With the Symplicity Spyral™ Multi-electrode Renal Denervation System

  NCT02439775· Medtronic Vascular· Source

• Completed

  Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation

  NCT01938248· Phase 4· Population Health Research Institute· Source

• Completed

  A Randomized Controlled Trial of TNK-tPA Versus Standard of Care for Minor Ischemic Stroke With Proven Occlusion

  NCT02398656· Phase 3· University of Calgary· Source

• Terminated

  Blinded Randomized Trial of Anticoagulation to Prevent Ischemic Stroke and Neurocognitive Impairment in AF

  NCT02387229· Phase 3· Montreal Heart Institute· Source

• Withdrawn

  Improving Outcomes After Time Sensitive Prehospital Interventions: Rescu Epistry

  NCT04110912· Unity Health Toronto· Source

• Completed

  Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

  NCT02089217· Mayo Clinic· Source

• Terminated

  Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients

  NCT02085265· Phase 2· Sunnybrook Health Sciences Centre· Source

• Completed

  ADVATE/ ADYNOVI Hemophilia A Outcome Database (AHEAD)

  NCT02078427· Baxalta now part of Shire· Source

• Completed

  Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

  NCT00673842· Phase 3· University of Calgary· Source

• Completed

  A Study of the Efficacy and Safety of Ocrelizumab in Patients With Relapsing-Remitting Multiple Sclerosis

  NCT00676715· Phase 2· Genentech, Inc.· Source

• Completed

  Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

  NCT00217737· Phase 3· National Cancer Institute (NCI)· Source

Conditions

Diseases this institution publishes on or runs trials for.

• Multiple sclerosis90 works · 7 trials
• HIV66 works · 2 trials
• Depression24 works · 12 trials
• Cystic fibrosis22 works · 1 trial
• Spinal cord injury21 works · 1 trial
• Peripheral artery disease17 works · 1 trial
• Brain aneurysm14 works · 5 trials
• Neuromyelitis optica (NMOSD)8 works · 0 trials
• Haemophilia7 works · 5 trials
• Immune thrombocytopenia (ITP)6 works · 0 trials
• Polycystic kidney disease4 works · 1 trial
• Optic neuritis3 works · 0 trials