Bladder cancer trials in United States

In United States 259 Also abroad 625

259 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial
Where
Ames, Ankeny, Appleton, Aurora, Bemidji, Beverly Hills, Billings, Birmingham, Bloomington, Boone, Boston, Brookfield, Canton, Cape Girardeau, Carthage, Cherry Hill, Cheyenne, Chicago, Chilton, Cincinnati, Cleveland, Clive, Coeur d'Alene, Columbus, Corona, Dallas, Danville, Decatur, DeKalb, Denver, Derby, Des Moines, Dixon, Duarte, Edina, Edwards, Effingham, Eureka, Evanston, Fairfield, Fargo, Fayetteville, Flemington, Flushing, Fort Collins, Fort Dodge, Fort Worth, Franklin, Galesburg, Geneva, Germantown, Gilbert, Glenview, Grayslake, Great Falls, Greeley, Green Bay, Greenwich, Guilford, Highland Park, Highlands Ranch, Houston, Irvine, Jackson, Jacksonville, Jefferson, Jersey City, Kewanee, Lake Forest, Lancaster, Lebanon, Lexington, Livingston, Lone Tree, Long Branch, Los Angeles, Louisville, Loveland, Macomb, Marshalltown, Mattoon, Mequon, Milwaukee, Minneapolis, Missoula, Morgantown, New Brunswick, New Haven, Newnan, New Orleans, New York, North Haven, Oak Brook, Oconto Falls, O'Fallon, Oklahoma City, Orland Park, Oshkosh, Ottawa, Parkersburg, Pekin, Peoria, Peru, Philadelphia, Phoenix, Post Falls, Princeton, Racine, Richardson, Richmond, Rogers, Ruskin, Sacramento, Saint Johnsbury, Saint Louis Park, Salt Lake City, San Antonio, Sandpoint, Seattle, Sewell, Sheboygan, Sioux Falls, South Pasadena, Springdale, Springfield, Stamford, Stony Brook, Sturgeon Bay, Tampa, Tarzana, Temple, Toms River, Torrington, Trumbull, Upland, Urbana, Warrenville, Washington, Waterbury, Waterford, Waukee, Wauwatosa, Wesley Chapel, West Chester, West Des Moines, Westerly, Willow Grove, Worcester
Age
18 years and over
People
111
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07061964
No phaseTaking people
Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer
Where
Burlington
Age
18 years and over
People
56
Run by
Lahey Clinic
See details and how to joinNCT07187063
No phaseTaking people
A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States
Where
Arlington, Birmingham, Bryn Mawr, Charlotte, Chicago Ridge, Dallas, Frederick, Indianapolis, Jacksonville, Lakewood, Little Rock, Los Angeles, North Charleston, Phoenix, Rochester, Seattle, Sioux Falls, Spokane, St Louis, Syracuse, Troy, Wimauma
Age
18 years and over
People
150
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07309445
Phase 1Taking people
A Study of GEN1106 in Participants With Solid Tumors
Where
Germantown, Lake Success, Myrtle Beach, New Haven, San Antonio
Age
18 years and over
People
103 worldwide
Run by
Genmab
See details and how to joinNCT07416123 · EU 2025-523760-21-00
Phase 3Taking people
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
Where
Atlanta, Baltimore, Boston, Cincinnati, Cleveland, Germantown, Knoxville, Morristown, Nashville, New York, Norfolk, Philadelphia, Raleigh, Salt Lake City, Seattle, Traverse City, Washington D.C.
Age
18 years and over
People
590 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07419295 · EU 2024-520014-22-00
Phase 1Taking people
Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors
Where
New York, Omaha
Age
18 years and over
People
156 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07660055
No phaseNot yet taking people in United States
EHR Integrated Remote Patient Monitoring to Reduce Readmission for Patients With Bladder Cancer Undergoing Cystectomy
Where
Ann Arbor
Age
18 years and over
People
50
Run by
University of Michigan Rogel Cancer Center
See details and how to joinNCT07912034
No phaseTaking people
Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE)
Where
Omaha, Philadelphia
Age
18 years and over
People
92
Run by
Fox Chase Cancer Center
See details and how to joinNCT06396533
Phase 2Taking people
Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma
Where
Albany, Ann Arbor, Atlanta, Austin, Chicago, Cleveland, Columbus, Dallas, Gahanna, Greenwood, Houston, Indianapolis, Jeffersonville, Lisle, Loma Linda, Los Angeles, Mt. Pleasant, Nashville, Plymouth, Radnor, Royal Oak, Sewell, St Louis, Syracuse, Tampa
Age
18 years and over
People
285 worldwide
Run by
Tyra Biosciences, Inc
See details and how to joinNCT07265947 · EU 2025-523539-20-00
Phase 2Taking people
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
Where
Bala-Cynwyd, Cherry Hill, Chicago, Detroit, Houston, Indianapolis, Lisle, Little Rock, Madison, Myrtle Beach, New York, Philadelphia, Round Rock, Royal Oak, San Antonio, Stanford, Washington Township, Westwood, Willow Grove
Age
18 years and over
People
240 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07475806
Phase 2Taking people
Risk-Enabled Therapy After Initiating EV/Pembro for Bladder Cancer
Where
Philadelphia
Age
18 years and over
People
70
Run by
Fox Chase Cancer Center
See details and how to joinNCT07908979
Phase 3Taking people
Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer
Where
Albany, Annapolis, Atlanta, Austin, Bakersfield, Bala-Cynwyd, Boston, Cheektowaga, Cincinnati, Clive, Creve Coeur, Dallas, Denver, Fresno, Garden City, Germantown, Houston, Jacksonville, Jeffersonville, Lakeland, Lake Success, Lancaster, Largo, Lexington, Lisle, Little Rock, Los Angeles, Mobile, Morristown, Murrieta, Myrtle Beach, New York, Omaha, Orange, Philadelphia, Phoenix, Pittsburgh, Portland, Poughkeepsie, Quincy, Raleigh, Rochester, Santa Monica, Sarasota, Southaven, Spokane, St Louis, The Bronx, Tucson, Virginia Beach, Washington D.C., Wichita
Age
18 years and over
People
454 worldwide
Run by
Ferring Pharmaceuticals
See details and how to joinNCT06510374 · EU 2024-512029-10-00
Phase 3Taking people
A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer
Where
Annapolis, Atlanta, Austin, Bala-Cynwyd, Boise, Buffalo, Cheektowaga, Cincinnati, Columbus, Dallas, Denver, Germantown, Hanover, Houston, Indianapolis, Lake Success, Lakewood, Lancaster, Lisle, Little Rock, Los Angeles, Morristown, Myrtle Beach, Nashville, New Haven, New York, Orange, Philadelphia, Pittsburgh, San Diego, Sarasota, Seattle, Southhaven, The Bronx, Tucson, Washington D.C., Wichita
Age
18 years and over
People
250 worldwide
Run by
Ferring Pharmaceuticals
See details and how to joinNCT06545955 · EU 2024-512177-27-01
Phase 1Taking people
Study Investigating Intravesical HDAC Inhibition to Improve Response to Immuno-Oncology Agents
Where
Tampa
Age
18 years and over
People
12
Run by
H. Lee Moffitt Cancer Center and Research Institute
See details and how to joinNCT06963346
No phaseTaking people
Cancer Experience Registry (CER) for Cancer Patients and Caregivers
Where
Washington D.C.
Age
18 years and over
People
15,000
Run by
Cancer Support Community, Research and Training Institute, Philadelphia
See details and how to joinNCT02333604
No phaseTaking people
En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope Device
Where
Bethesda
Age
18 years to 120 years
People
25
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04235764
No phaseTaking people
Gender Related Coping and Survivorship for Genitourinary Cancers
Where
Baltimore, Washington D.C.
Age
18 years and over
People
80
Run by
Johns Hopkins University
See details and how to joinNCT05649306
Phase 2Taking people
18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection
Where
Bethesda
Age
18 years to 120 years
People
320
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06503146
No phaseTaking people
Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy
Where
Ann Arbor, Iowa City, Nashville, New Brunswick, Tampa
Age
18 years and over
People
500 worldwide
Run by
Photocure
See details and how to joinNCT07144319
Phase 1/2Taking people
A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)
Where
Austin, Bakersfield, Myrtle Beach, New Brunswick
Age
18 years and over
People
45 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07222488 · EU 2025-520467-40-00
No phaseNot yet taking people in United States
Circulating Tumor DNA (ctDNA) in High Grade Upper Tract Urothelial Cancer (UTUC)
Where
Baltimore
Age
18 years and over
People
20
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT07793240
Phase 1Taking people
A Study of MGC026 in Participants With Advanced Solid Tumors
Where
Grand Rapids, Houston, Lake Success, Los Angeles, Portland, West Valley City
Age
18 years and over
People
394 worldwide
Run by
MacroGenics
See details and how to joinNCT06242470
Phase 3Taking people
Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
Where
Aurora, Austin, Charlottesville, Columbia, Eugene, Fairfield, Fort Wayne, Hinsdale, Las Vegas, Little Rock, Nashville, Newark, New Lenox, New York, Niles, Norfolk, Royal Oak, Santa Barbara, St Louis, Tigard, Tyler
Age
18 years and over
People
390 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07566156 · EU 2026-525612-34-00
No phaseTaking people
A Study of a Side Effects and Resource Navigation Program for People With Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
18 years and over
People
200
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07646847
Phase 2Taking people
Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
Where
Astoria, Austin, Bala-Cynwyd, Baltimore, Charleston, Chicago Ridge, Columbus, Dallas, Durham, Germantown, Greenwood, Homewood, Houston, Jeffersonville, Kansas City, Lancaster, Lisle, Little Rock, Morristown, Murrieta, Myrtle Beach, Nashville, New York, North Charleston, Plymouth, Raleigh, Rancho Mirage, San Antonio, San Diego, Springfield, St Louis, Syracuse, The Bronx, Voorhees Township
Age
18 years and over
People
90 worldwide
Run by
Tyra Biosciences, Inc
See details and how to joinNCT06995677 · EU 2025-521277-14-00