COPD trials in United States

In United States 122 Also abroad 557

122 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
The Increase of Lung Capacity Using the Lung Master (Pulmonary Exerciser)
Where
Omaha
Age
19 years and over
People
20
Run by
University of Nebraska
See details and how to joinNCT06524856
No phaseTaking people
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Where
Ann Arbor, Birmingham, Boston, Chicago, Cleveland, Columbus, DuBois, Falls Church, Gilbert, Houston, Jascksonville, Kansas City, Milwaukee, Orlando, Peoria, Philadelphia, Pittsburgh, Sacramento
Age
40 years to 84 years
People
250 worldwide
Run by
Apreo Health, Inc.
See details and how to joinNCT06891755
Phase 4Taking people
Compare the Effects of Nebulizer Versus Inhaler Based Therapy for COPD Using Long-acting Bronchodilators
Where
Knoxville
Age
40 years and over
People
72
Run by
University of Tennessee Graduate School of Medicine
See details and how to joinNCT07133880
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Where
Allen, Anderson, Ann Arbor, Beaumont, Bellaire, Boerne, Boston, Boynton Beach, Carrollton, Chandler, Chicago, Chicago Ridge, Chickasha, Cordele, Corsicana, Cutler Bay, Cypress, Dallas, Dayton, DeSoto, Doral, Durham, East Orange, Evanston, Fargo, Fayetteville, Flushing, Fort Myers, Harlingen, Henderson, Hickory, Houston, Indianapolis, Kansas City, Kingwood, Lady Lake, Lampasas, Lancaster, La Palma, Long Beach, Los Angeles, Madison Heights, Miami, Miami Lakes, Morrisville, Nashville, Newport Beach, Orlando, Palm Beach Gardens, Pembroke Pines, Philadelphia, Phoenix, Pittsburgh, Portland, Redding, Rochester, San Antonio, Sioux Falls, Surprise, Tampa, Valencia, Williamsburg, Winston-Salem, Zachary
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190209 · EU 2024-518016-39-00
No phaseTaking people
STRIVE Post-Market Registry Study
Where
Anderson, Baltimore, Boston, Chicago, Coral Gables, Dallas, Durham, Gulfport, Hershey, Houston, Mountain View, Philadelphia, Phoenix, Shreveport
Age
18 years and over
People
150
Run by
Olympus Corporation of the Americas
See details and how to joinNCT04302272
Phase 1Taking people
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for Pulmonary Diseases
Where
Naples
People
20 worldwide
Run by
The Foundation for Orthopaedics and Regenerative Medicine
See details and how to joinNCT05147688
No phaseTaking people
Comprehensive Patient-Centered Home-based Care Coaching for COPD Self-management
Where
New York
Age
40 years and over
People
300
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT06634810
Phase 4Taking people
This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization
Where
Mullica Hill
Age
40 years and over
People
754 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07587658 · EU 2025-524392-23-00
No phaseTaking people
The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry
Where
Columbus, Durham, Houston, Indianapolis, Kingwood, Lawrence, North Richland Hills
Age
40 years and over
People
350
Run by
Sanofi
See details and how to joinNCT07612878
No phaseTaking people
A Multi Center Study Testing a New Implant for Adults With Severe Emphysema
Where
Boston, Chicago, Milwaukee, San Francisco
Age
22 years and over
People
60
Run by
Pulmair Medical, Inc.
See details and how to joinNCT07119229
Phase 4Not yet taking people in United States
Study to Evaluate the Effects of Oral Glyceryl Guiacolate (Guaifenesin, GGE) on Sputum Rheology in Subjects With Mucus Hypersecretion
Where
Chapel Hill
Age
40 years to 75 years
People
40
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT07873632
Phase 1/2Not yet taking people in United States
A Study to Investigate Small Mobile Stem Cells (SMS) in Moderate to Severe Chronic Obstructive Pulmonary Disease
Where
Miami
Age
18 years and over
People
125
Run by
SMSbiotech
See details and how to joinNCT07871890
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
Where
Adairsville, Anderson, Ann Arbor, Atlanta, Baltimore, Bay Pines, Birmingham, Boerne, Bowling Green, Boynton Beach, Charlotte, Clearwater, Colchester, Columbia, Concord, Cordele, Cullman, Decatur, El Paso, Evanston, Evansville, Everett, Fayetteville, Fleming Island, Fort Eisenhower, Gaffney, Grants Pass, Hannibal, Hendersonville, Hinsdale, Horsham, Houston, Indianapolis, Inglewood, Jacksonville, Kansas City, Kenosha, Knoxville, Lebanon, Leesburg, Lewisville, Little River, Los Angeles, Margate, McKinney, Mesquite, Miami, Miami Lakes, Minneapolis, New Britain, Ocala, Oklahoma City, Owensboro, Palmetto Bay, Palo Alto, Phoenix, Pittsburgh, Potomac, Rapid City, Redding, Rosedale, San Antonio, San Diego, Savannah, Sayre, Scottsdale, Spartanburg, Springfield, Staten Island, Syracuse, The Bronx, Tulsa, Union, Williamsburg, Wilmington, Winter Park
Age
40 years to 80 years
People
990 worldwide
Run by
AstraZeneca
See details and how to joinNCT06878261 · EU 2024-517457-27-00
No phaseTaking people
COPD Resources, Education, and Activity Designed for You Study
Where
Chicago
Age
40 years and over
People
448
Run by
Rush University Medical Center
See details and how to joinNCT07125053
No phaseTaking people
Emphysema Research Registry and Biosample Repository
Where
Pittsburgh
Age
21 years and over
People
3,000
Run by
University of Pittsburgh
See details and how to joinNCT00307281
No phaseTaking people
Evaluation of the Paramedic Evaluation for Acute COPD Exacerbation
Where
Worcester
Age
40 years and over
People
75
Run by
University of Massachusetts, Worcester
See details and how to joinNCT07072039
No phaseTaking people
Acoustic Waveform Respiratory Evaluation
Where
Indianapolis, Pittsburgh
Age
8 years to 70 years
People
800
Run by
Indiana University
See details and how to joinNCT06512064
Phase 3Taking people
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
Where
Bakersfield, Baltimore, Bradenton, Brandon, Chicago, Clarkston, Corsicana, Dallas, Flint, Franklin, Greenville, Henderson, Hialeah, Houston, Las Vegas, Loxahatchee Groves, McKinney, Miami, Miami Lakes, Modesto, Newport Beach, North Massapequa, Orange City, Palmetto Bay, Palm Springs, Pearland, Pensacola, Reno, Riverdale, Rock Hill, St Louis, Stonecrest, Tamarac, Tampa, The Villages, Wilmington, Winston-Salem
Age
40 years to 80 years
People
981 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06959095 · EU 2024-520418-22-00
Phase 3Taking people
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Where
Adairsville, Allen Park, Atlanta, Aurora, Austin, Bangor, Baton Rouge, Boise, Brooksville, Chicago, Cordele, Dallas, Detroit, Doral, DuBois, El Paso, Fall River, Fort Lauderdale, Garden City, Houston, Knoxville, Lafayette, Lampasas, Las Vegas, Miami, Miami Lakes, Moorestown, Morgantown, Morrow, Mount Kisco, Naples, New Port Richey, New Windsor, Ocala, Orlando, Ormond Beach, Palmetto Bay, Pembroke Pines, Philadelphia, Richmond, Rockville, San Antonio, Sewell, Sheffield, Shelby, Shreveport, Spartanburg, St. Petersburg, Troy, Union, Webster
Age
40 years to 80 years
People
961 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06961214 · EU 2024-520417-41-00
No phaseEnrolling by invitation
Personalizing Veterans' Lung Cancer Screening and Diagnosis
Where
Aurora, Chicago, Kansas City, Louisville, Nashville, Salisbury, Seattle
Age
50 years to 80 years
People
1,400
Run by
VA Office of Research and Development
See details and how to joinNCT07838519
Phase 3Taking people
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Where
Abilene, Albany, Albuquerque, Amarillo, Anderson, Ann Arbor, Apple Valley, Athens, Aurora, Austin, Beavercreek, Blue Ash, Boise, Boston, Bountiful, Boynton Beach, Bradenton, Bronxville, Brooklyn, Brownsville, Camp Hill, Canoga Park, Cape Coral, Castroville, Charleston, Chattanooga, Chicago, Clearwater, Cleveland, Columbia, Columbus, Crystal River, Cudahy, Cullman, Cutler Bay, Dallas, Denver, DuBois, Edgewater, Elizabethton, El Paso, Englewood, Exton, Fairhope, Fayetteville, Flint, Forney, Fort Lauderdale, Fort Myers, Franklin, Fremont, Gaffney, Gardena, Garden Grove, Georgetown, Gilbert, Glen Burnie, Glendale, Grand Island, Grants Pass, Greensboro, Greenville, Gulfport, Hialeah, Hollywood, Homestead, Houston, Huntersville, Huntsville, Inglewood, Kansas City, Katy, Kerrville, Kingwood, Kissimmee, Lafayette, Lake City, Lakeland, Lake Worth, La Mesa, La Palma, Las Vegas, Lawrence, Lewisville, Lexington, Liberty, Lincoln, Lomita, Long Beach, Los Alamitos, Loxahatchee Groves, Marion, Massapequa, McAllen, McKinney, Medford, Mesa, Miami, Miami Lakes, Milwaukee, Mission Viejo, Missoula, Mobile, Monroe, Morehead City, Morgantown, Morristown, Mullica Hill, Naples, Newport Beach, Newport News, Newton, New Windsor, New York, Norfolk, Norman, North Hollywood, Ocala, Ogden, Oklahoma City, Olive Branch, Omaha, Orlando, Ormond Beach, Oxon Hill, Paducah, Paris, Peachtree Corners, Pembroke Pines, Philadelphia, Phoenix, Pierre, Plano, Plantation, Pomona, Potomac, Raleigh, Rapid City, Richmond, Roseburg, Sacramento, Salisbury, Salt Lake City, San Bernardino, San Diego, San Dimas, Santa Ana, Savannah, Sheffield, Shreveport, Sioux City, Sioux Falls, Southfield, Spartanburg, Spokane, Statesville, St Louis, St. Petersburg, Suffolk, Sun City Center, Tamarac, Tampa, Tarzana, Tempe, The Bronx, Thousand Oaks, Toledo, Toms River, Tucker, Tucson, Tullahoma, Tulsa, Union, Union City, Valparaiso, Van Nuys, Vestal, Victoria, Vista, Waco, Washington D.C., West Jordan, Westminster, West Valley City, Wichita, Wichita Falls, Wilmington, Winfield, Winston-Salem, Wylie, Zachary
Age
40 years to 80 years
People
5,250 worldwide
Run by
AstraZeneca
See details and how to joinNCT06283966 · EU 2023-507407-59-00
No phaseTaking people
Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF
Where
Boston
Age
40 years and over
People
136
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT05934565
No phaseNot yet taking people in United States
Developing an Intervention to Optimize Virtual Care Adoption for COPD Management
Where
Bedford, Boston
Age
40 years and over
People
40
Run by
VA Office of Research and Development
See details and how to joinNCT05986214
Phase 1Taking people
: Vascular Function in Health and Disease
Where
Salt Lake City
Age
18 years and over
People
420
Run by
D. Walter Wray
See details and how to joinNCT02966665
No phaseEnrolling by invitation
Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs
Where
Baltimore, Boston, Charlottesville, Dallas, Durham, Houston, Jacksonville, Philadelphia, Phoenix, Pittsburgh, San Francisco, Stanford, The Bronx
People
3,500 worldwide
Run by
Paragonix Technologies
See details and how to joinNCT04930289