COPD trials in United States

In United States 122 Also abroad 557

122 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
Where
Boston, Chicago, Cleveland, Dallas, Detroit, Falls Church, Hartford, Knoxville, Lexington, Loveland, Milwaukee, Orlando, Peoria, Philadelphia, Phoenix, Pittsburgh
Age
40 years to 80 years
People
200 worldwide
Run by
Pulmonx Corporation
See details and how to joinNCT06035120
Phase 4Taking people
Nebulizer Versus Handheld Maintenance Therapy for Patients With COPD
Where
Saint Charles, Winston-Salem
Age
60 years and over
People
120
Run by
COPD Foundation
See details and how to joinNCT07816835
No phaseEnrolling by invitation
Titrated Ambulatory Oxygen in Fibrotic ILD and COPD With Isolated Exertional Hypoxemia
Where
Buffalo
Age
18 years to 85 years
People
24
Run by
State University of New York at Buffalo
See details and how to joinNCT07512687
Phase 2Taking people
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
Where
Ann Arbor, Baltimore, Birmingham, Chicago, Colchester, Denver, Detroit, Durham, Houston, Iowa City, Jacksonville, Kansas City, Nashville, New York, Philadelphia, Pittsburgh, San Francisco, Seattle, Tucson
Age
40 years and over
People
334
Run by
Johns Hopkins University
See details and how to joinNCT07059091
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Where
Albuquerque, Atlanta, Baltimore, Buffalo, Chicago, Clearfield, Clearwater, Columbia, Columbus, Cortland, Cudahy, Cutler Bay, Dallas, DeBary, DuBois, Farmington Hills, Foley, Forney, Fort Worth, Franklin, Gainesville, Garden Grove, High Point, Homestead, Horseheads, Houston, Humble, Johnson City, Kerrville, Kings Mountain, Las Vegas, Lithonia, Mansfield, Massapequa, Meridian, Miami, Millville, Milwaukee, Missoula, Mobile, Morgantown, Munster, New Bern, Newport Beach, North Dartmouth, Oklahoma City, Orlando, Palos Hills, Papillion, Philadelphia, Phoenix, Rincon, Rock Hill, Saint Cloud, Sewell, Sheffield, St Louis, Tampa, The Bronx, Toms River, Torrance, Tucson, Wilmington, Winfield, Winston-Salem
Age
40 years to 80 years
People
990 worldwide
Run by
AstraZeneca
See details and how to joinNCT06883305 · EU 2024-517458-90-00
No phaseTaking people
COPD Exacerbation Follow Up
Where
Cherry Hill, Falls Church, Milwaukee, Park Ridge, Philadelphia
Age
40 years and over
People
485
Run by
Viz.ai, Inc.
See details and how to joinNCT07118306
No phaseTaking people
Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction
Where
Boston
Age
40 years to 75 years
People
20
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT05257681
Phase 2Taking people
Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With Hypoxemia
Where
Durham
Age
40 years and over
People
10
Run by
Bastiaan Driehuys
See details and how to joinNCT07037836
No phaseTaking people
Photon-counting CT in Chest Imaging
Where
Durham
People
40
Run by
Duke University
See details and how to joinNCT07031336
No phaseEnrolling by invitation
Virtual Nurse and Social Worker Palliative Care Team to Improve Quality of Life in Veterans With Heart Failure or COPD
Where
Aurora, Cheyenne, Lebanon, Long Beach, Phoenix, Providence, Shreveport
Age
18 years and over
People
420
Run by
VA Office of Research and Development
See details and how to joinNCT07714252
No phaseEnrolling by invitation
Goal Concordant Care Learning Laboratory
Where
Durham
Age
18 years and over
People
5,000
Run by
Duke University
See details and how to joinNCT05879211
No phaseTaking people
Improving Patient-Centered Care for Underserved Older African American Patients With Cardiovascular Comorbidities
Where
Birmingham
Age
50 years to 99 years
People
29
Run by
University of Alabama at Birmingham
See details and how to joinNCT07748858
Phase 2Not yet taking people in United States
GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD
Where
Cleveland
Age
40 years to 80 years
People
30
Run by
The Cleveland Clinic
See details and how to joinNCT07747805
Phase 3Taking people
Multi-Center Clean Air Randomized Controlled Trial in COPD
Where
Ann Arbor, Baltimore, Birmingham, Boston, Cleveland, Iowa City, Lebanon, Los Angeles, Salisbury, West Reading
Age
40 years and over
People
770
Run by
JHSPH Center for Clinical Trials
See details and how to joinNCT06376994
Phase 3Taking people
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Where
Allen Park, Bangor, Boise, Bowling Green, Brandon, Clarkston, Cordele, Crystal River, Dallas, Dearborn, DeSoto, Doral, DuBois, Dunwoody, Edmond, Greenacres City, Greenville, Henderson, Hialeah, Hollywood, Houston, Katy, Knoxville, Lake Charles, Lakewood, Las Vegas, Mesquite, Miami, Miami Lakes, Newport Beach, Orlando, Reno, Rock Hill, Shreveport, Stafford, West Chester, Winston-Salem
Age
40 years to 75 years
People
1,196 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07177339 · EU 2025-521108-23-00
No phaseTaking people
PEP Buddy in Pulmonary Rehabilitation
Where
Cincinnati, Cleveland
Age
40 years to 89 years
People
120
Run by
VA Office of Research and Development
See details and how to joinNCT07404826
No phaseTaking people
Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention
Where
Boise, Chicago, Minneapolis, Seattle, Spokane
Age
18 years and over
People
400
Run by
Seattle Institute for Biomedical and Clinical Research
See details and how to joinNCT06390345
No phaseTaking people
MoblO2 to Maintain Oxygenation
Where
Denver
Age
25 years to 95 years
People
48
Run by
Minnesota HealthSolutions
See details and how to joinNCT07704567
No phaseNot yet taking people in United States
Modulating Locomotor-Respiratory Coupling Through Adaptive Exoskeleton Assistance in Patients With COPD
Where
Omaha
Age
45 years to 75 years
People
10
Run by
University of Nebraska
See details and how to joinNCT07703527
No phaseTaking people
Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer
Where
Coon Rapids, Dallas, Fridley, Memphis, Minneapolis, Redondo Beach, Richardson
Age
18 years and over
People
1,200
Run by
Helio Genomics
See details and how to joinNCT05181826
Phase 1Taking people
A Study of BBT002 in Healthy Volunteers (HVs) and in Adult Patients With Chronic Obstructive Pulmonary Disease (COPD) or Chronic Rhiosininusitis With Nasal Polyps (CRSwNP)
Where
Bowling Green, New York, Owensboro
Age
18 years to 80 years
People
286 worldwide
Run by
Bambusa Therapeutics
See details and how to joinNCT06944925 · EU 2025-523142-28-00
No phaseTaking people
Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease
Where
Kansas City
Age
18 years to 65 years
People
8
Run by
University of Kansas Medical Center
See details and how to joinNCT06985225
Phase 3Enrolling by invitation
Long Term Safety of Alpha1-Proteinase Inhibitor in Subjects With Alpha1 Antitrypsin Deficiency
Where
Charleston, Miami, Phoenix, Portland, Tyler, Wilmington
Age
20 years to 72 years
People
290 worldwide
Run by
Grifols Therapeutics LLC
See details and how to joinNCT02796937
No phaseTaking people
Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital
Where
Birmingham, Des Moines, New York, Philadelphia
Age
22 years and over
People
70
Run by
Fisher and Paykel Healthcare
See details and how to joinNCT07222410
No phaseTaking people
Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD
Where
Miami
Age
18 years to 100 years
People
45
Run by
University of Miami
See details and how to joinNCT06578156