Epilepsy trials in United States

In United States 208 Also abroad 452

53 of 208 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Evaluation and Treatment of Neurosurgical Disorders
Where
Bethesda
Age
4 years to 99 years
People
5,000
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT00060541
No phaseTaking people
Tumor Related Epilepsy
Where
Bethesda
Age
8 years to 99 years
People
100
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT02639325
No phaseEnrolling by invitation
Study of Direct Brain Recording and Stimulation for Memory Enhancement
Where
Bethesda
Age
18 years to 65 years
People
200
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT04095026
No phaseTaking people
Genetic Markers of Cardiovascular Disease in Epilepsy
Where
Rochester
Age
18 years to 50 years
People
600
Run by
Mayo Clinic
See details and how to joinNCT02824822
No phaseTaking people
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Where
Sioux Falls
People
20,000
Run by
Sanford Health
See details and how to joinNCT01793168
No phaseTaking people
PET/MRI/EEG Imaging Study in Epilepsy
Where
Charlestown
Age
18 years and over
People
30
Run by
Massachusetts General Hospital
See details and how to joinNCT06974305
No phaseTaking people
Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG)
Where
Boston, Phoenix
Age
6 years and over
People
90
Run by
CREmedical
See details and how to joinNCT05944692
No phaseTaking people
Surgery as a Treatment for Medically Intractable Epilepsy
Where
Bethesda
Age
8 years to 99 years
People
300
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT01273129
No phaseTaking people
Investigating Epilepsy: Screening and Evaluation
Where
Bethesda
Age
8 years to 110 years
People
1,000
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT03478852
No phaseTaking people
Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up
Where
Ann Arbor, Billings, Birmingham, Boston, Charlotte, Cleveland, Durham, Indianapolis, Jacksonville, Miami, Minneapolis, New Haven, Palo Alto, Philadelphia, Phoenix, Rochester, San Diego, St Louis, Tampa
Age
18 years to 75 years
People
210
Run by
Epiminder America, Inc.
See details and how to joinNCT07110454
No phaseTaking people
Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database
Where
Bethesda
Age
8 years to 120 years
People
700
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT02107989
No phaseTaking people
Artificial Intelligence for Brain MRI Analysis in Epilepsy
Where
Bethesda, Charleston, Chicago, Oakland, Philadelphia, Washington D.C.
People
2,000 worldwide
Run by
Istituto Giannina Gaslini
See details and how to joinNCT07881185
No phaseTaking people
Post-Market Real-World Evidence Registry for the NeuroOne OneRF® Ablation System for Epilepsy
Where
Livingston, Miami, New Brunswick
People
100
Run by
NeuroOne Medical Technologies Corporation
See details and how to joinNCT07546253
No phaseEnrolling by invitation
RNS System for Drug-Resistant Focal Epilepsy in Adolescents: A Real-World Study
Where
Waltham
Age
13 years to 19 years
People
100
Run by
NeuroPace
See details and how to joinNCT07823465
No phaseTaking people
Prospective Natural History Study of POLG Disease
Where
Akron, Aurora, Dallas, Houston, New York, Philadelphia, San Diego
People
300 worldwide
Run by
The POLG Foundation
See details and how to joinNCT07775872
No phaseTaking people
Physiological Brain Atlas Development
Where
Nashville
Age
6 years to 90 years
People
5,000
Run by
Vanderbilt University Medical Center
See details and how to joinNCT00575081
No phaseEnrolling by invitation
Cor360: Clinician-Facing Broad-Spectrum Cardiac Phenotyping and Risk Assessment Using COR® Wearable ECG to Inform Outcomes-Oriented Care Pathways
Where
Nashville, Pasadena
Age
18 years and over
People
1,000
Run by
Peerbridge Health, Inc
See details and how to joinNCT07775976
No phaseTaking people
A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders
Where
Bethesda
Age
1 month to 100 years
People
999
Run by
National Human Genome Research Institute (NHGRI)
See details and how to joinNCT06092346
No phaseTaking people
Brain Development Research Program
Where
San Francisco
People
2,000
Run by
University of California, San Francisco
See details and how to joinNCT00305305
No phaseTaking people
Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome
Where
Ann Arbor, Chicago, Columbus, St Louis
Age
Up to 26 years
People
4,680
Run by
Ann & Robert H Lurie Children's Hospital of Chicago
See details and how to joinNCT05374824
No phaseEnrolling by invitation
EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment
Where
Chicago
Age
2 years to 35 years
People
20
Run by
University of Chicago
See details and how to joinNCT07555171
No phaseTaking people
SLC6A1-NDD Prospective Longitudinal Natural History Study
Where
New York
Age
Up to 17 years
People
60 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT07531511
No phaseTaking people
Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight
Where
Boston, Lewisburg
People
100,000
Run by
Simons Searchlight
See details and how to joinNCT01238250
No phaseTaking people
MEHMO Natural History and Biomarkers
Where
Bethesda
Age
1 week to 100 years
People
150
Run by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
See details and how to joinNCT06019182
No phaseEnrolling by invitation
Epilepsy Emergency Department High Utilizer Program
Where
Atlanta
Age
18 years and over
People
15
Run by
Morehouse School of Medicine
See details and how to joinNCT07663240