Epilepsy: open trials in United States

208 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT06593951
Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1)
Research · Boston Children's Hospital
Boston Childrens Hospital, Boston
Registry updated 2026-03-18
NCT05819268
A Multi-site Feasibility Clinical Trial of Retraining and Control Therapy (ReACT), a Mind and Body Treatment for Pediatric Functional Seizures
Trial Treatment · University of Alabama at Birmingham
University of Alabama at Birmingham, Birmingham
Registry updated 2026-03-17
NCT06007053
Retraining and Control Therapy (ReACT) R33 Phase
Trial Treatment · University of Alabama at Birmingham
University of Alabama at Birmingham, Birmingham
Registry updated 2026-03-17
NCT05996900
Investigating the Neural Mechanisms of Repetitive Brain Stimulation With Invasive and Noninvasive Electrophysiology in Humans
Trial Treatment · Stanford University
Stanford University, Stanford
Registry updated 2026-03-12
NCT05289934
Effects of Recorded Music on Clinical and EEG Seizure Activity
Trial Treatment · Johns Hopkins University
Johns Hopkins School of Medicine, Baltimore
Registry updated 2026-03-06
NCT05871372
Intracranial Investigation of Neural Circuity Underlying Human Mood
Trial Treatment · Baylor College of Medicine
Baylor College of Medicine, Houston
Registry updated 2026-03-04
NCT05082181
Telephone-Based Support Programs for People With Epilepsy
Trial Treatment · NYU Langone Health
NYU Langone Health, New York
Registry updated 2026-02-17
NCT07413211
Genetic Developmental and Epileptic Encephalopathy Natural History Study for Clinical Trial Readiness
Research · Weill Medical College of Cornell University
Weill Cornell Medicine, New York
Registry updated 2026-02-17
NCT04649008
Localizing Epileptic Networks Using MRI and iEEG
Trial Treatment · Early phase 1 · University of Pennsylvania
University of Pennsylvania, Philadelphia
Registry updated 2026-02-13
NCT01694940
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Research · Columbia University
Akron Children's Hospital, Akron · Children's Hospital of Colorado, Aurora · Massachusetts General Hospital, Boston · Cleveland Clinic, Cleveland · Case Western Reserve University, Clevland · University of Florida, Gainsville · Baylor College of Medicine, Houston · Columbia University Medical Center, New York · Virtual Site (Remote enrollment), New York · The Children's Hospital Of Philadelphia, Philadelphia · Children's Hospital of Pittsburgh, Pittsburgh · Mayo Clinic, Rochester · University of California San Diego, San Diego · Seattle Children's Hospital and Regional Medical Center, Seattle · Lucile Packard Children's Hospital, Stanford · Children's National Medical Center, Washington D.C.
Registry updated 2026-02-04
NCT07145489
Infrared Photobiomodulation in Humans With Epilepsy
Trial Treatment · Beth Israel Deaconess Medical Center
BIDMC, Boston
Registry updated 2026-02-04
NCT05673915
Study of Transcranial Direct Current Stimulation to Treat Epilepsy
Trial Treatment · Mayo Clinic
Mayo Clinic Minnesota, Rochester
Registry updated 2026-01-28
NCT06551090
Prediction of Anxiety and Memory State
Trial Treatment · Columbia University
Columbia University Irving Medical Center, New York
Registry updated 2026-01-28
NCT06938542
Palliative Care Needs of Children With Rare Diseases and Their Families
Trial Treatment · Children's National Research Institute
Children's National Hospital, Washington D.C.
Registry updated 2026-01-28
NCT05899764
Epileptic Hippocampus in Alzheimer's Disease
Trial Treatment · Phase 1/2 · University of California, Los Angeles
Mary S. Easton Center for Alzheimer's Research and Care, Los Angeles
Registry updated 2026-01-27
NCT07219407
A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
Trial Treatment · Phase 2 · Rapport Therapeutics Inc.
Consultants in Epilepsy and Neurology PLLC, Boise · Cleveland Clinic Foundation, Cleveland · Baylor College of Medicine, Houston · Vanderbilt University Medical Center, Nashville · NYU Langone Comprehensive Epilepsy Center, New York · University of Pennsylvania - Department of Neurology, Philadelphia · Mayo Clinic, Rochester
Registry updated 2026-01-23
NCT07353918
Low-Intensity Focused Ultrasound Neuromodulation for Epilepsy
Trial Treatment · Carilion Clinic
Fralin Biomedical Research Institute at VTC, Roanoke
Registry updated 2026-01-21
NCT05529264
Human Intracranial Electrophysiology
Trial Treatment · Dartmouth-Hitchcock Medical Center
Dartmouth Hitchcock Medical Center, Lebanon
Registry updated 2026-01-15
NCT01858285
Genetics of Epilepsy and Related Disorders
Research · Boston Children's Hospital
Boston Children's Hospital, Boston
Registry updated 2026-01-09
NCT07329257
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)
Research · University of Missouri-Columbia
University of Missouri - Columbia, Columbia
Registry updated 2026-01-09
NCT06422923
A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)
Trial Treatment · Phase 1/2 · Neurona Therapeutics
University of Colorado Anschutz Medical Campus, Aurora · Atrium Health, Charlotte · UVA Health University Medical Center, Charlottesville · University of Chicago, Chicago · Duke University Hospital, Durham · UTHealth Houston, Houston · University of Iowa Health Care, Iowa City · University of Arkansas for Medical Sciences, Little Rock · University of Southern California Keck Hospital, Los Angeles · Medical College of Wisconsin, Milwaukee · UC Irvine Medical Center, Orange · Stanford University, Palo Alto · Oregon Health and Science University, Portland · University of California San Diego, San Diego · University of California San Francisco, San Francisco · SUNY Upstate Medical University, Syracuse · Wake Forest Baptist Medical Center, Winston-Salem
Registry updated 2026-01-07
NCT05273970
Electrochemical and Electrophysiological Study
Trial Treatment · University of Arizona
Banner - University Medical Center, Phoenix campus, Phoenix
Registry updated 2025-12-17
NCT05431595
Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy
Trial Treatment · Phase 2/3 · M.D. Anderson Cancer Center
MD Anderson Cancer Center, Houston
Registry updated 2025-11-18
NCT04788628
Auditory Stimulation Effects on Sleep and Memory in Patients With Epilepsy
Trial Treatment · Massachusetts General Hospital
Massachusetts General Hospital, Boston
Registry updated 2025-11-17
NCT07226908
Human Thalamus in Propagation of Temporal Lobe Seizures and Memory Formation
Trial Treatment · Stanford University
Stanford Hospital, Stanford
Registry updated 2025-11-12

All Epilepsy trials and the map

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