Heart failure: open trials in United Kingdom

• NCT00271180

  Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

  Research · Medtronic

  Birmingham · Blackpool · Bristol · Leeds · Leicester · Liverpool · London · Manchester · Middlesbrough · Northampton · Nottingham · Sheffield · Southampton

  Registry updated 2026-11-04

• NCT06736574

  Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

  Trial Treatment · Phase 3 · Cytokinetics

  Basingstoke and North Hampshire Hospital, Basingstoke · Castle Hill Hospital, Cottingham · Russells Hall Hospital, Dudley · Ulster Hospital, Dundonald · Glasgow Royal Infirmary, Glasgow · Queen Elizabeth University Hospital, Glasgow · Harefield Hospital, Harefield · Southampton General Hospital, Southampton · Great Western Hospitals, Swindon

  Registry updated 2026-11-04

• NCT06678841

  ELEVATE-HFpEF Clinical Study

  Trial Treatment · Medtronic Cardiac Rhythm and Heart Failure

  The Leeds Teaching Hospitals NHS Trust, Leeds General Infirmary, Leeds · Guys and St Thomas NHS Foundation Trust - St Thomas Hospital, London · Manchester University NHS Foundation Trust - Manchester Royal Infirmary, Manchester

  Registry updated 2026-11-03

• NCT05714085

  Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

  Trial Treatment · Phase 2/3 · Merck Sharp & Dohme LLC

  Great Ormond Street Hospital For Children NHS Foundation Trust ( Site 3401), London · Freeman Hospital ( Site 3400), Newcastle upon Tyne

  Registry updated 2026-10-30

• NCT07037459

  Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  Trial Treatment · Phase 3 · Amgen

  University Hospital Monklands, Airdrie · North Tyneside General Hospital, Ashington · Ormeau Clinical Trials Ltd, Belfast · Royal Bournemouth Hospital, Bournemouth · Princess of Wales Hospital, Bridgend · Southmead Hospital, Bristol · St Richards Hospital, Chichester · Ninewells Hospital and Medicine School, Dundee · Royal Devon and Exeter Hospital, Exeter · Glasgow Royal Infirmary, Glasgow · Monkfield Medical Practice, Great Cambourne · Wycombe Hospital, High Wycombe · Highlands Clinical Research Facility, Raigmore Hospital, Inverness · University Hospital Crosshouse, Kilmarnock · Glenfield Hospital, Leicester · Kings College Hospital, London · University College London Hospital, London · St Georges Hospital, London · Manchester Royal Infirmary, Manchester · Newcastle NIHR Commercial Research Delivery Centre, Newcastle upon Tyne · Craigavon Area Hospital, Portadown, Craigavon · Ashfields Primary Care Centre, Sandbach · University Hospital of North Tees, Stockton-on-Tees · Breckland Alliance Research, Thetford · Pinderfields Hospital, Wakefield · Marine Lake & Estuary Medical Practice, West Kirby

  Registry updated 2026-10-29

• NCT06424288

  A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

  Trial Treatment · Phase 3 · Boehringer Ingelheim

  Barnet Hospital, Barnet · Southmead Hospital, Bristol · Royal Devon and Exeter Hospital (Wonford), Exeter · Calderdale Royal Hospital, Halifax · Wycombe Hospital, High Wycombe · St. Bartholomew's Hospital, London · The Royal Oldham Hospital, Oldham · Northern General Hospital, Sheffield · Royal Cornwall Hospital, Truro · York Hospital, York

  Registry updated 2026-10-28

• NCT06935370

  A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

  Trial Treatment · Phase 3 · Boehringer Ingelheim

  Southmead Hospital, Bristol · Golden Jubilee National Hospital, Clydebank · Royal Devon and Exeter Hospital (Wonford), Exeter · Calderdale Royal Hospital, Halifax · Northwick Park Hospital, Harrow · St. Bartholomew's Hospital, London

  Registry updated 2026-10-28

• NCT07192952

  A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

  Trial Treatment · Phase 3 · Bayer

  Royal Belfast Hospital for Sick Children | Paediatric Cardiology, Belfast · Bristol Royal Hospital for Children | Clinical Research Facility, Bristol · Royal Hospital for Children | Glasgow Clinical Research Facility, Glasgow · Leeds Children's Hospital | Children's Research Facility, Leeds · Leicester Children's Hospital | Children's Research Facility, Leicester · Alder Hey Children's Hospital | Clinical Research Facility, Liverpool · Freeman Hospital | Children's Heart Unit, Newcastle upon Tyne

  Registry updated 2026-10-27

• NCT06991257

  A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

  Trial Treatment · Phase 2 · Pfizer

  South Eastern Health and Social Care Trust, Belfast · St Richard's Hospital, Chichester · Ninewells Hospital and Medical School, Dundee · Wycombe General Hospital, High Wycombe · St. George's Hospital, London · Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich · Northern General Hospital, Sheffield

  Registry updated 2026-10-23

• NCT06677060

  Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

  Trial Treatment · Phase 3 · AstraZeneca

  Aberdeen · Chesterfield · Dundee · Gatley · Glasgow · London · Norwich · Penzance · Redruth · Sandbach · Southampton · Swansea · Weston-super-Mare · Wolverhampton · Woodbridge · Yate

  Registry updated 2026-10-21

• NCT07207811

  CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis

  Trial Treatment · Phase 3 · Novo Nordisk A/S

  Synexus Scotland Clinical Research Centre, Bellshill · Synexus Midlands Clinical Research Centre, Birmingham · Synexus Wales Clinical Research Centre, Cardiff · Synexus Merseyside Clinical Research Centre, Liverpool · Richmond Pharmacology - MHRA Phase 1 Unit, London · The Royal Free Hospital - Royal Free London NHS Foundation Trust, London · Synexus Manchester Clinical Research Centre, Manchester

  Registry updated 2026-10-21

• NCT07713719

  Arterial Stiffness and Endothelial Function in Heart Failure

  Research · Coventry University

  University Hospitals Coventry and Warwickshire, Coventry

  Registry updated 2026-10-21

• NCT07880730

  Right Heart Injury Monitoring on ECMO

  Research · Papworth Hospital NHS Foundation Trust

  Royal Papworth Hospital NHS Foundation Trust, Cambridge

  Registry updated 2026-10-19

• NCT04141605

  Global Utilization And Registry Database for Improved heArt preservatioN

  Research · Paragonix Technologies

  Manchester University, Manchester

  Registry updated 2026-10-16

• NCT07188805

  A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

  Trial Treatment · Phase 3 · Bayer

  Belfast Health and Social Care Trust | Royal Belfast Hospital for Sick Children - Paediatric Cardiology, Belfast · University Hospitals Bristol and Weston NHS Foundation Trust | Bristol Royal Hospital for Children - Clinical Research Facility, Bristol · NHS Greater Glasgow and Clyde | Royal Hospital for Children - Glasgow Clinical Research Facility, Glasgow · Leeds Teaching Hospitals NHS Trust | Leeds Children's Hospital - Children's Research Facility, Leeds · University Hospitals of Leicester NHS Trust | Leicester Children's Hospital - Children's Research Facility, Leicester · Alder Hey Children's NHS Foundation Trust | Alder Hey Children's Hospital - Clinical Research Facility, Liverpool · Newcastle upon Tyne Hospitals NHS Foundation Trust |Freeman Hospital - Children's Heart Unit, Newcastle upon Tyne

  Registry updated 2026-10-15

• NCT07830719

  Dose-finding Study of YMI024 to Assess Efficacy, Safety, and Tolerability in Adults With Stable Coronary Artery Disease and Elevated hsCRP

  Trial Treatment · Phase 2 · Novartis Pharmaceuticals

  London

  Registry updated 2026-10-15

• NCT06307652

  Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

  Trial Treatment · Phase 3 · AstraZeneca

  Airdrie · Barnet · Cambridge · Clydebank · Exeter · Harefield · Hastings · High Wycombe · Kent · Kings Lynn · Lincoln · London · Middlesbrough · Portsmouth · Sheffield · Sunderland · Wakefield

  Registry updated 2026-10-13

• NCT07057466

  Prospective Evaluation of AI-ECG for SHD Detection

  Research · Imperial College London

  Bristol Royal Infirmary, Bristol · Southmead Hospital, Bristol · West Middlesex University Hospital, London · St Mary's Hospital, London · Chelsea And Westminster Hospital, London · Hammersmith Hospital, London

  Registry updated 2026-10-08

• NCT07235462

  A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world Setting

  Research · Bayer

  Many Locations, Multiple Locations

  Registry updated 2026-10-08

• NCT06979362

  A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

  Trial Treatment · Phase 2 · Novo Nordisk A/S

  Trialmed - Midlands, Birmingham · Wycombe General Hospital, High Wycombe · St Bartholomew's Hospital - Cardiac Research Office, London · St Bartholomew's Hospital - Cardiology, London · King's College Hospital, London · The Royal Brompton Hospital - Respiratory CRF, London · The James Cook University Hospital - Cardiology, Middlesbrough · Southampton General Hospital, Southampton

  Registry updated 2026-10-05

• NCT07500948

  Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation

  Trial Treatment · University of Leicester

  Glenfield Hospital, University Hospitals of Leicester NHS Trust, Groby Road, Leicester

  Registry updated 2026-10-05

• NCT07622472

  Remote Monitoring and Optimization of Heart Failure Therapy

  Trial Treatment · Zoll Medical Corporation

  Southampton University Hospital NHS Foundation Trust, Southampton

  Registry updated 2026-10-05

• NCT07367841

  FIND HF Risk-guided Screening for Heart Failure - Pilot Study

  Research · University of Leeds

  University of Leeds, Leeds

  Registry updated 2026-10-02

• NCT07852221

  Patient Selection and Long-Term Outcomes of Pace & Ablate Strategy in Atrial Fibrillation

  Research · Insel Gruppe AG, University Hospital Bern

  Liverpool Heart and Chest Hospital, Liverpool

  Registry updated 2026-10-01

• NCT07761117

  A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

  Trial Treatment · Phase 3 · AstraZeneca

  Ashton-under-Lyne · Basildon · Belfast · Birmingham · Brighton · Bristol · Cardiff · Clydebank · Dundee · Glasgow · Kings Lynn · Leeds · London · Sandbach · Southampton · Woodbridge

  Registry updated 2026-09-28

All Heart failure trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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