Heart failure trials in United States
387 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.
- No phaseTaking peoplePOCUS-Guided Diuresis for Decompensated Heart Failure
- Where
- Pittsburgh
- Age
- 18 years and over
- People
- 588
- Run by
- University of Pittsburgh
See details and how to joinNCT06921603 - No phaseNot yet taking people in United StatesEvaluation of the HeartLogic Diagnostic in Optimizing Guideline-directed Medical Therapy in Patients With Congestive Heart Failure and Chronically Low Ejection Fractions (EFs)
- Where
- Indianapolis, Nashville
- Age
- 18 years and over
- People
- 135
- Run by
- Robert Pickett
See details and how to joinNCT07412626 - No phaseTaking peopleIdentifying Markers of Exercise Training in Heart Failure
- Where
- Stanford
- Age
- 18 years to 89 years
- People
- 90
- Run by
- Stanford University
See details and how to joinNCT05696652 - No phaseTaking peopleAdult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
- Where
- Baltimore, Grand Rapids, New York
- Age
- 18 years and over
- People
- 400 worldwide
- Run by
- Leiden University Medical Center
See details and how to joinNCT06932081 - No phaseEnrolling by invitationBiventricular Remodeling in Transcatheter Tricuspid Valve Replacement - Acute Hemodynamic Instability Study
- Where
- New York
- Age
- 18 years and over
- People
- 140
- Run by
- Columbia University
See details and how to joinNCT06954792 - No phaseTaking peopleCardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment
- Where
- Chandler, Gilbert, Phoenix, San Tan Valley
- Age
- 18 years and over
- People
- 300 worldwide
- Run by
- Aventyn, Inc.
See details and how to joinNCT07403669 - Phase 2/3Taking peopleOptimizing HFrEF Patients Using BaroStim and CardioMems
- Where
- Riverhead
- Age
- 18 years to 80 years
- People
- 15
- Run by
- Northwell Health
See details and how to joinNCT07399587 - No phaseTaking peopleHeart Failure Precision Medicine Study
- Where
- Sacramento
- Age
- 21 years and over
- People
- 100
- Run by
- University of California, Davis
See details and how to joinNCT04196842 - No phaseTaking peopleHis-Bundle Corrective Pacing in Heart Failure
- Where
- Asheville, Burlington, Chicago, Los Angeles, New York, Philadelphia, Phoenix, Richmond, Ridgewood, Tampa, Wilkes-Barre
- Age
- 18 years and over
- People
- 120
- Run by
- University of Rochester
See details and how to joinNCT05265520 - No phaseTaking peopleCardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction
- Where
- Atlanta, Clearwater, Cleveland, Detroit, Madison
- Age
- 21 years to 90 years
- People
- 250
- Run by
- BioCardia, Inc.
See details and how to joinNCT06258447 - Early phase 1Taking peopleKetones, SGLT2, HFrEF
- Where
- San Antonio
- Age
- 18 years to 70 years
- People
- 71
- Run by
- The University of Texas Health Science Center at San Antonio
See details and how to joinNCT06229678 - No phaseTaking peopleiCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure
- Where
- Chicago
- Age
- 18 years and over
- People
- 360
- Run by
- University of Illinois Chicago
See details and how to joinNCT06205225 - No phaseTaking peoplePharmacy-led Transitions of Care Intervention to Improve Medication Adherence
- Where
- Knoxville, Memphis
- Age
- 18 years and over
- People
- 388
- Run by
- University of Tennessee
See details and how to joinNCT06374277 - No phaseNot yet taking people in United StatesFeasibility and Acceptability of Three Component Intervention for the Heart Failure Care for Rural Dwelling Participants
- Where
- Birmingham
- Age
- 18 years and over
- People
- 32
- Run by
- University of Alabama at Birmingham
See details and how to joinNCT07103239 - No phaseEnrolling by invitationAdvancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes
- Where
- Boston
- Age
- 18 years and over
- People
- 1,006
- Run by
- Brigham and Women's Hospital
See details and how to joinNCT05443321 - Phase 2Taking peopleTransplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients
- Where
- Dallas, Durham, Los Angeles
- Age
- 18 years to 90 years
- People
- 15
- Run by
- Baylor Research Institute
See details and how to joinNCT03383419 - No phaseTaking peopleCardiopulmonary Stress Testing (CPET) AlloSure Study
- Where
- Dallas
- Age
- 18 years and over
- People
- 27
- Run by
- Baylor Research Institute
See details and how to joinNCT04656080 - Early phase 1Taking peopleAcute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes
- Where
- San Antonio
- Age
- 18 years to 80 years
- People
- 10
- Run by
- The University of Texas Health Science Center at San Antonio
See details and how to joinNCT06108076 - No phaseTaking peopleHIV+ Deceased Donor Heart Transplant Study for HIV+ Recipients
- Where
- Dallas
- Age
- 18 years and over
- People
- 50
- Run by
- University of Texas Southwestern Medical Center
See details and how to joinNCT06659952 - No phaseTaking peopleProspective Observational Study of the ICD in Sudden Cardiac Death Prevention
- Where
- Baltimore, Richmond, Washington D.C.
- Age
- 18 years to 85 years
- People
- 1,500
- Run by
- Johns Hopkins University
See details and how to joinNCT00733590 - No phaseTaking peopleSensor-controlled Digital Game for Heart Failure Self-management: A Clinical Trial
- Where
- Austin
- Age
- 45 years and over
- People
- 200
- Run by
- University of Texas at Austin
See details and how to joinNCT05056129 - No phaseTaking peopleHemodynamic Assessment of underLying myocyTe Function in Right Heart Failure
- Where
- Baltimore
- Age
- 18 years to 90 years
- People
- 50
- Run by
- Johns Hopkins University
See details and how to joinNCT06299436 - No phaseTaking peopleEffect of Music on Cardiopulmonary Exercise Capacity in Heart Failure Patients
- Where
- Lexington
- Age
- 18 years and over
- People
- 40
- Run by
- Maya Ignaszewski
See details and how to joinNCT05537467 - No phaseTaking peopleREHAB Fontan Failure: A Trial of Cardiac Rehabilitation
- Where
- Nashville, Stanford
- Age
- 18 years and over
- People
- 50
- Run by
- Stanford University
See details and how to joinNCT06150950 - No phaseEnrolling by invitationMultidisciplinary Ventricular Assist Device Clinic
- Where
- Boston
- Age
- 18 years and over
- People
- 110
- Run by
- Massachusetts General Hospital
See details and how to joinNCT05388019