Heart failure trials in United States

In United States 387 Also abroad 1266

387 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Early phase 1Taking people
Diffusion MRI in Heart Failure
Where
Charlestown
Age
18 years to 85 years
People
160
Run by
Massachusetts General Hospital
See details and how to joinNCT02973633
No phaseTaking people
His Bundle Pacing in Bradycardia and Heart Failure
Where
Rochester
Age
18 years and over
People
80
Run by
Yong-Mei Cha
See details and how to joinNCT03008291
No phaseTaking people
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
Where
Charlottesville
Age
18 years and over
People
70
Run by
University of Virginia
See details and how to joinNCT06009276
No phaseTaking people
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance
Where
Charlotte, Cincinnati, Cleveland, Falls Church, Minneapolis
Age
18 years and over
People
125 worldwide
Run by
Minneapolis Heart Institute Foundation
See details and how to joinNCT07131631
No phaseTaking people
Imaging Histone Deacetylase in the Heart
Where
Boston
Age
18 years to 85 years
People
96
Run by
Massachusetts General Hospital
See details and how to joinNCT03549559
No phaseTaking people
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
Where
Charleston, Chicago, Gainesville, Kansas City, Rochester, Salt Lake City, San Francisco
Age
18 years to 100 years
People
150
Run by
International Consortium of Circulatory Assist Clinicians
See details and how to joinNCT06039176
No phaseEnrolling by invitation
Subspecialty Ambulatory Quality Cardiology Program
Where
New York
Age
18 years to 90 years
People
7,000
Run by
NYU Langone Health
See details and how to joinNCT07283666
Phase 2/3Taking people
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
Where
Dallas, Pittsburgh, Richmond
Age
18 years and over
People
240
Run by
VA Office of Research and Development
See details and how to joinNCT04982419
No phaseTaking people
A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure
Where
Boston, Cleveland
Age
18 years to 100 years
People
120
Run by
Tufts Medical Center
See details and how to joinNCT05627440
No phaseTaking people
Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure
Where
Naperville
Age
18 years and over
People
2,150
Run by
Endotronix, Inc.
See details and how to joinNCT06783335
No phaseEnrolling by invitation
Ketone and Hawthorn Extract Supplementation in Congestive Heart Failure
Where
Philadelphia
Age
18 years and over
People
45
Run by
Thomas Jefferson University
See details and how to joinNCT07166965
No phaseTaking people
Salivary Extracellular Vesicle Associated lncRNAs in Heart Failure (SEAL-HF)
Where
Boston
Age
18 years and over
People
90
Run by
Massachusetts General Hospital
See details and how to joinNCT06169540
No phaseTaking people
Eat Well Heart Failure
Where
Durham
Age
18 years and over
People
900
Run by
Duke University
See details and how to joinNCT07101289
No phaseTaking people
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD - Longitudinal Aim
Where
Nashville
Age
10 years and over
People
10
Run by
Vanderbilt University Medical Center
See details and how to joinNCT06093100
No phaseTaking people
Enhanced Nutritional Optimization in LVAD Trial
Where
New York
Age
18 years and over
People
50
Run by
Columbia University
See details and how to joinNCT05655910
Phase 2/3Taking people
Tailored Exercise Training Study Among Adults With HFpEF
Where
Dallas
Age
18 years and over
People
120
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07223242
No phaseTaking people
Pulmonary Artery Catheter in Cardiogenic Shock Trial
Where
Boston
Age
18 years to 90 years
People
400
Run by
Tufts Medical Center
See details and how to joinNCT05485376
No phaseTaking people
US Benchmarking Clinical Study
Where
Boston
Age
60 years and over
People
150
Run by
eMyosound SAS
See details and how to joinNCT07215715
Phase 1/2Enrolling by invitation
Enhancing the Natriuretic Peptide System in HFpEF
Where
Rochester
Age
18 years and over
People
60
Run by
Horng Chen
See details and how to joinNCT05279742
Phase 2Taking people
Ertugliflozin in Chronic Heart Failure
Where
New Haven
Age
18 years and over
People
60
Run by
Yale University
See details and how to joinNCT04438213
No phaseTaking people
Left vs Left Randomized Clinical Trial
Where
Albuquerque, Allentown, Arlington, Asheville, Boston, Burlington, Chapel Hill, Charleston, Charlotte, Charlottesville, Chicago, Cincinnati, Cleveland, Davie, Denver, Evanston, Falls Church, Gilbert, Greenville, Hackensack, Hartford, Houston, Indianapolis, Jacksonville, La Jolla, Lancaster, Little Rock, Littleton, Louisville, Marlton, Miami Beach, Naperville, Newark, New Haven, Newport News, New York, Palm Beach Gardens, Philadelphia, Pittsburgh, Portland, Richmond, Ridgewood, Rochester, Salt Lake City, Scranton, Seattle, South Pasadena, Tampa, Tucson
Age
18 years and over
People
2,136 worldwide
Run by
Baylor College of Medicine
See details and how to joinNCT05650658
No phaseTaking people
Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction
Where
Farmington
Age
50 years to 80 years
People
30
Run by
UConn Health
See details and how to joinNCT05174351
No phaseTaking people
A Nurse-Led Weight Monitoring Intervention For Heart Failure Quality of LIfe and Self-Care
Where
Avon
Age
55 years and over
People
42
Run by
Lee Anne Siegmund
See details and how to joinNCT07184541
No phaseTaking people
Multi-Site Feasibility Testing of the Ventricular Assist Device Anticipatory Guidance Tool
Where
Lincoln, Milwaukee
Age
19 years and over
People
10
Run by
Bryan Heart
See details and how to joinNCT06823583
Phase 4Taking people
Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
Where
Brooklyn, Columbia, Detroit, Madison, Omaha, Richmond, Rochester, Rome, Salt Lake City, Scottsdale, Shawnee Mission, Tyler
Age
18 years and over
People
2,000
Run by
University of Rochester
See details and how to joinNCT06964464