Heart failure trials in United States

In United States 387 Also abroad 1266

387 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
UIC Multi-Ethnic DCM Registry
Where
Chicago
Age
18 years and over
People
1,500
Run by
University of Illinois Chicago
See details and how to joinNCT07145138
Phase 3Taking people
MYTHS - MYocarditis THerapy With Steroids
Where
Charlottesville, Houston, Richmond, San Diego
Age
18 years to 69 years
People
288 worldwide
Run by
Niguarda Hospital
See details and how to joinNCT05150704
No phaseTaking people
Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients
Where
Lewisburg
Age
18 years to 64 years
People
95
Run by
West Virginia School of Osteopathic Medicine
See details and how to joinNCT06049420
No phaseTaking people
Integration of Telemedicine and Home-Based Cardiac Rehabilitation: Feasibility, Efficacy, and Adherence
Where
Brookfield
Age
18 years and over
People
500
Run by
ROM Technologies, INC
See details and how to joinNCT05972070
No phaseTaking people
Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
Where
Ann Arbor
Age
18 years and over
People
30
Run by
University of Michigan
See details and how to joinNCT06337812
No phaseTaking people
The PeriCut Catheter System Early Feasibility Study (REIMAGINE-HFpEF)
Where
Rochester
Age
30 years and over
People
10
Run by
Heart Failure Solutions, Inc.
See details and how to joinNCT06702501
No phaseTaking people
The Epidemiology and Pathophysiology of Kidney Disease in HFpEF With Obesity
Where
Jackson
Age
18 years to 75 years
People
60
Run by
University of Mississippi Medical Center
See details and how to joinNCT07052539
No phaseTaking people
PRIME HFrEF: Novel Exercise for Older Patients With Heart Failure With Reduced Ejection Fraction
Where
Charlottesville
Age
65 years and over
People
92
Run by
University of Virginia
See details and how to joinNCT05609097
No phaseEnrolling by invitation
Heart Failure Food Intervention Trial: Impact of a Guideline-based Nutrition Digital Tool in Heart Failure Patient Clinical Outcomes
Where
Walnut Creek
Age
18 years to 89 years
People
180
Run by
Sutter Health
See details and how to joinNCT06999369
No phaseTaking people
A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System
Where
Boston
Age
22 years to 88 years
People
10
Run by
Vectorious Medical Technologies Ltd.
See details and how to joinNCT06147336
No phaseEnrolling by invitation
Gut Microbiome Profiling in Patients With Chronic Heart Failure
Where
Stanford
Age
18 years to 75 years
People
150
Run by
Stanford University
See details and how to joinNCT06361524
Phase 1Taking people
Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure
Where
Houston
Age
18 years to 79 years
People
24
Run by
Medley Therapeutics
See details and how to joinNCT06831825
Phase 1Taking people
Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
Where
Chicago, Dallas
Age
18 years and over
People
12
Run by
Secretome Therapeutics
See details and how to joinNCT06560762
No phaseTaking people
Studies of Neuregulin/ERBB Signaling in Human Heart
Where
Portland
Age
18 years and over
People
80
Run by
Douglas B. Sawyer
See details and how to joinNCT02820233
No phaseTaking people
At-Home Cardiac Rehabilitation for Adolescents at Risk for Heart Failure
Where
Los Angeles
Age
0 years to 21 years
People
20
Run by
Children's Hospital Los Angeles
See details and how to joinNCT06826534
Phase 1Taking people
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Where
Aurora, Baltimore, Boston, Cleveland, New York, Rochester, San Francisco
Age
18 years to 65 years
People
15
Run by
Tenaya Therapeutics
See details and how to joinNCT06228924
No phaseTaking people
Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)
Where
Lancaster
Age
18 years and over
People
150
Run by
Lancaster General Hospital
See details and how to joinNCT06688396
No phaseTaking people
Get With The Guidelines-Heart Failure Registry
Where
Dallas
Age
18 years to 125 years
People
128,026
Run by
American Heart Association
See details and how to joinNCT02693509
No phaseTaking people
Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure
Where
San Diego
Age
13 years to 39 years
People
150
Run by
Hari Narayan
See details and how to joinNCT04262830
No phaseEnrolling by invitation
Cardiac Abnormalities in Stroke Prevention and Risk of Recurrence
Where
Camden
Age
18 years and over
People
2,000
Run by
The Cooper Health System
See details and how to joinNCT06398366
No phaseEnrolling by invitation
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
Where
Melbourne
Age
18 years and over
People
15,000
Run by
Peerbridge Health, Inc
See details and how to joinNCT06763549
No phaseTaking people
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
Where
Aurora, Baltimore, Boston, Charleston, Cleveland, New York, Rochester, San Francisco
Age
14 years to 65 years
People
200 worldwide
Run by
Tenaya Therapeutics
See details and how to joinNCT06311708
Phase 3Taking people
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Where
Albuquerque, Alexander City, Ann Arbor, Atlanta, Aurora, Birmingham, Boston, Buffalo, Charlotte, Chicago, Cincinnati, Dallas, Durham, Elk Grove Village, Fort Lauderdale, Germantown, Grand Blanc, Haddon Heights, Haverhill, Hershey, Honolulu, Indianapolis, Manhasset, Marietta, Miami, Natick, New Brunswick, New Orleans, Newton, New York, Peoria, Philadelphia, Pittsburgh, Rockville, San Antonio, Tucson, Washington D.C.
Age
50 years to 99 years
People
2,000 worldwide
Run by
Uppsala University
See details and how to joinNCT02901184 · EU 2024-517448-79-00
No phaseTaking people
Identification of Genomic Predictors of Adverse Events After Cardiac Surgery
Where
Boston, Dallas, Houston
Age
20 years to 90 years
People
4,000
Run by
Brigham and Women's Hospital
See details and how to joinNCT01258231
No phaseTaking people
HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry
Where
Austin, Bloomington, Columbia, Houston, Kansas City, La Jolla, Maplewood, Minneapolis, Portland, Raleigh, Sioux Falls
Age
18 years to 100 years
People
2,000
Run by
University of Kansas Medical Center
See details and how to joinNCT06425848