Heart failure trials in United States

In United States 387 Also abroad 1266

387 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in United States
Wearable Technology in Heart Failure Patients
Where
Cleveland
Age
18 years to 85 years
People
500
Run by
The Cleveland Clinic
See details and how to joinNCT07650669
Phase 3Taking people
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Where
Anchorage, Annapolis, Arlington, Atlanta, Baltimore, Bethlehem, Beverly Hills, Bossier City, Boston, Bradenton, Bridgeton, Bridgewater, Brooklyn, Buffalo, Burlington, Champaign, Chapel Hill, Chicago, Colorado Springs, Columbus, Covington, Dallas, Dayton, DeSoto, Durham, East Providence, El Paso, Fairhope, Fargo, Flint, Gilbert, Grand Forks, Greensboro, Gurnee, Hallandale, Houston, Humble, Huntington Beach, Huntington Park, Indianapolis, Jacksonville, Kansas City, Kingwood, Lafayette, Lakeland, Lanham, Leavenworth, Lincoln, Loma Linda, Lomita, Mather, Maumee, Media, Melrose Park, Miami, Miami Lakes, Millville, Moline, Morgantown, New Bedford, New Haven, New Orleans, New York, Niles, Northridge, Ocala, Ocoee, Oklahoma City, Owensboro, Oxon Hill, Palmetto Bay, Palo Alto, Philadelphia, Plano, Rapid City, Redding, Redmond, Riverview, Rockford, Rosedale, San Antonio, San Diego, Schaumburg, Sewell, Shreveport, Smithfield, Southfield, Spartanburg, Statesville, Sun City, Tampa, Tarzana, The Bronx, Tomball, Trenton, Troy, Tucker, Tyler, Victoria, Vineland, Waterloo, Wichita, Wilmington, Winfield, Worcester, Yardley, Zachary
Age
18 years and over
People
6,950 worldwide
Run by
AstraZeneca
See details and how to joinNCT07761117 · EU 2026-526304-79-00
Phase 1Taking people
: Vascular Function in Health and Disease
Where
Salt Lake City
Age
18 years and over
People
420
Run by
D. Walter Wray
See details and how to joinNCT02966665
Phase 4Taking people
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure
Where
Charlotte, Columbus, Philadelphia
Age
18 years to 130 years
People
60 worldwide
Run by
AstraZeneca
See details and how to joinNCT06651970
Phase 1Not yet taking people in United States
Positron Emission Tomography (PET) Imaging of Chemotherapy-Induced Cardiotoxicity
Where
St Louis
Age
21 years to 99 years
People
36
Run by
Washington University School of Medicine
See details and how to joinNCT07838649
No phaseTaking people
Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
Where
Charleston, Dallas, Los Angeles, Minneota
Age
18 years and over
People
149 worldwide
Run by
Echosens
See details and how to joinNCT07222813
Phase 4Taking people
Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
Where
San Antonio
Age
30 years to 70 years
People
78
Run by
The University of Texas Health Science Center at San Antonio
See details and how to joinNCT05838287
No phaseTaking people
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
Where
Ann Arbor, Augusta, Birmingham, Charleston, Chicago, Cincinnati, Columbus, Durham, Houma, Houston, Indianapolis, La Jolla, New York, Phoenix, Richmond, Rochester, San Francisco, Springfield, St Louis
Age
40 years and over
People
150 worldwide
Run by
Axon Therapies, Inc.
See details and how to joinNCT04592445
No phaseEnrolling by invitation
Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)
Where
Boston, Charleston, Chicago, Durham, Houston, Madison, Milwaukee
Age
22 years to 85 years
People
50
Run by
Gradient Denervation Technologies
See details and how to joinNCT06052072
No phaseTaking people
Improving the Collaborative Health of Adult Dyads
Where
Columbia
Age
18 years and over
People
500
Run by
University of South Carolina
See details and how to joinNCT05370014
No phaseTaking people
Tezspire Cardiac Events PASS
Where
Wilmington
Age
12 years to 130 years
People
16,640 worldwide
Run by
AstraZeneca
See details and how to joinNCT06951867
No phaseNot yet taking people in United States
Utilization of Guided Point of Care Ultrasound in Heart Failure Diagnosis Pilot Trial
Where
Grand Rapids
Age
18 years and over
People
100
Run by
Corewell Health West
See details and how to joinNCT07828834
No phaseTaking people
Cholate Clearance in Fontan and Heart Failure
Where
Philadelphia
Age
18 years and over
People
75
Run by
HepQuant, LLC
See details and how to joinNCT07009132
No phaseNot yet taking people in United States
Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure
Where
Aurora
Age
18 years and over
People
585
Run by
VA Office of Research and Development
See details and how to joinNCT07714239
No phaseTaking people
Clinical Evaluation of NIRSense Tissue Oximetry Sensor Monitoring to Early Detect Cardiogenic Shock
Where
Weston
Age
18 years and over
People
20
Run by
NIRSense Inc.
See details and how to joinNCT07825363
No phaseTaking people
Tier Palliative Care For Patients With Advanced Heart Failure or Cancer
Where
Astoria, New York
Age
18 years and over
People
400
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07391956
No phaseNot yet taking people in United States
10 Degree C Static Storage in Heart Transplantation
Where
Nashville
Age
18 years and over
People
25
Run by
John Trahanas
See details and how to joinNCT07818941
Phase 3Taking people
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
Where
Akron, Amarillo, Atlanta, Aurora, Austin, Baltimore, Bartlesville, Baton Rouge, Birmingham, Boise, Boston, Bowie, Bradenton, Brooksville, Burlington, Camden, Centerville, Charleston, Chicago, Chula Vista, Cincinnati, Cynthiana, Dallas, Denver, Duluth, Fairhope, Fort Lauderdale, Fort Myers, Germantown, Glendale, Glenview, Greenville, Hammond, Hialeah, Houston, Huntington Beach, Huntsville, Indianapolis, Jacksonville, Kansas City, Lexington, Los Angeles, Louisville, Memphis, Merrillville, Miami, Milwaukee, Minneapolis, Miramar, Naperville, Nashville, Norfolk, Omaha, Paducah, Peoria, Philadelphia, Phoenix, Pittsburgh, Plano, Providence, Richmond, Roslyn, Sacramento, Salem, San Francisco, Scottsdale, Spokane, Stony Brook, Tamarac, Tarzana, Tupelo, Van Nuys, West Hills, West Monroe
Age
18 years and over
People
5,200 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06008197
Phase 3Taking people
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
Where
Amarillo, Atlanta, Aurora, Austin, Baton Rouge, Bradenton, Centerville, Charlotte, Chattanooga, Chula Vista, Denison, Denver, El Centro, Fairhope, Fort Lauderdale, Fort Worth, Glenview, Greenville, Hialeah, Houston, Island Lake, Kansas City, Layton, Lexington, Louisville, Merrillville, Miami, Minneapolis, Miramar, Morrisville, Naperville, Norfolk, Omaha, Paducah, Peoria, Philadelphia, Phoenix, Sacramento, Salem, San Francisco, Texarkana, Van Nuys, West Monroe
Age
18 years and over
People
1,500 worldwide
Run by
Colorado Prevention Center
See details and how to joinNCT06024746
No phaseTaking people
Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
Where
Cleveland, Houston
Age
18 years and over
People
400 worldwide
Run by
Oslo University Hospital
See details and how to joinNCT07436299
No phaseEnrolling by invitation
Multimodal Physiologic State Intelligence Study
Where
New York
Age
18 years and over
People
25,000
Run by
Truway Health, Inc.
See details and how to joinNCT07814118
No phaseTaking people
Echocardiographic Assessment of the Effect of Impella on Biventricular Function
Where
Rochester
Age
18 years and over
People
24
Run by
University of Rochester
See details and how to joinNCT07534462
No phaseTaking people
Pedal Pump Clinical Trial on Edema V2
Where
Tulsa
Age
18 years and over
People
30
Run by
Hillcrest
See details and how to joinNCT07809516
Phase 1Taking people
Mechanisms of Diuretic Resistance in Heart Failure, Aim 2
Where
New Haven
Age
18 years and over
People
50
Run by
Yale University
See details and how to joinNCT05753059
No phaseTaking people
A Study Of Acute Decompensated Heart Failure
Where
Rochester
Age
18 years and over
People
500
Run by
Mayo Clinic
See details and how to joinNCT07572955