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Huntington's disease: open trials in United States

21 open trials have a site in United States. Registry data; only the trial team decides who can take part.

  • NCT07378644

    Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease

    Trial Treatment · Phase 2/3 · Skyhawk Therapeutics, Inc.

    Beth Israel Deaconess Medical Center, Boston · Massachusetts General Hospital, Charlestown · The Ohio State University, Columbus · CenExel Denver, CO, Englewood

    Registry updated 2026-11-06

  • NCT07609108

    Pridopidine Phase 3 Study in Huntington's Disease

    Trial Treatment · Phase 3 · Prilenia

    Johns Hopkins University, Baltimore · The University of Alabama at Birmingham, Birmingham · University of Miami-U Health Boca Raton, Boca Raton · University of Vermont Medical Center, Burlington · Massachusetts General Hospital, Charlestown · Northwestern University, Chicago · Rush University Medical Center, Chicago · University of Cincinnati, Cincinnati · Cleveland Clinic, Cleveland · The Ohio State University, Columbus · Duke University, Durham · University of Florida, Norman Fixel Institute for Neurological Diseases, Gainesville · Struthers Parkinson's Center / Health Partners Institute, Golden Valley · UT Health, Houston, McGovern Medical School, Houston · University of Kansas Medical Center, Kansas City · EvergreenHealth - Research Department, Kirkland · University of California San Diego, La Jolla · UCLA Medical Center, Los Angeles · Vanderbilt University Medical Center, Nashville · Columbia University, New York · Oregon Health and Science university (OHSU), Portland · UC Davis Medical Center, Sacramento · University of Washington, Seattle · Georgetown University, Washington D.C. · Hereditary Neurological Disease Centre, Wichita

    Registry updated 2026-11-04

  • NCT07280650

    Feasibility and Acceptability of an LLM-based Chatbot for Family Caregivers: Evaluation Study

    Trial Treatment · University of Michigan

    University of Michigan, Ann Arbor

    Registry updated 2026-10-26

  • NCT07315984

    Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease

    Research · BioSensics

    Vanderbilt University Medical Center, Nashville · University of Rochester Medical Center, Rochester

    Registry updated 2026-10-13

  • NCT07326709

    A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

    Trial Treatment · Phase 3 · Novartis Pharmaceuticals

    Albany Medical College, Albany · Grady Memorial Hospital and Clinics, Atlanta · Johns Hopkins University, Baltimore · University of Alabama Birmingham, Birmingham · Beth Israel Deaconess Med Ctr, Boston · UBMD Neurology, Buffalo · The University of Vermont MC, Burlington · University Of NC At Chapel Hill, Chapel Hill · Parkinsons-Movement Disorder Ctr, Chicago · Rush University Medical Center, Chicago · Cleveland Clinic Foundation, Cleveland · Henry Ford Health System, Detroit · Duke University Health System, Durham · CenExcel Rocky Mtn Clin Research, Englewood · University of Kansas Hospital, Fairway · U Conn Health, Farmington · TX Movement Disorder Spec PLLC, Georgetown · Trinity Health Michigan, Grand Rapids · U of TX Health Science Ct, Houston · Indiana University Health, Indianapolis · University of Iowa Health Care, Iowa City · University of CA San Diego, La Jolla · Univ of Arkansas for Med Sciences, Little Rock · Uni Of Wisconsin Hosp And Clinic, Madison · Veracity Neuroscience LLC, Memphis · UM Department Of Neurology, Miami · Vanderbilt University Medical CenterX, Nashville · Columbia University Irving Medical, New York · University of Pennsylvania, Philadelphia · University of Pittsburgh, Pittsburgh · Oregon Health Sciences University, Portland · VCU Health Systems MCV, Richmond · Universi of Rochester School of Med, Rochester · UC Davis Health System, Sacramento · UCSF, San Francisco · University of Washington Medical Center, Seattle · Stanford Healthcare, Stanford · University of South Florida, Tampa · Georgetown University, Washington D.C. · Hereditary Neurological Disease Centre, Wichita

    Registry updated 2026-09-22

  • NCT07010705

    Digital Measures for Clinical Trial Endpoints in Huntington's Disease

    Research · University of Rochester

    University of Rochester Medical Center, Rochester

    Registry updated 2026-08-17

  • NCT06826612

    A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

    Trial Treatment · Phase 1/2 · Hoffmann-La Roche

    Beth Israel Deaconess Medical Center, Boston · University of Cincinnati/Cincinnati Children's Hospital, Cincinnati · Ohio State University, Columbus · University of Pennsylvania, Philadelphia · University of Pittsburg, Pittsburgh

    Registry updated 2026-05-05

  • NCT02855476

    HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

    Research · University College, London

    John Hopkins University, Baltimore · CenExel, Englewood · University of Texas Health Science Center, Houston · Vanderbilt University Medical Center, Nashville · Georgetown University, Washington D.C. · Wake Forest University, Winston-Salem

    Registry updated 2026-04-27

  • NCT07451613

    Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease

    Trial Treatment · Phase 1/2 · Leslie Thompson

    University of California, Irvine, Irvine

    Registry updated 2026-04-13

  • NCT06546488

    Cognitive Assessment Tools for Huntington's Disease.

    Research · Ohio State University

    The Ohio State University -Wexner Medical Center, Columbus

    Registry updated 2026-03-02

  • NCT05326451

    Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's Disease

    Trial Treatment · The University of Texas Health Science Center, Houston

    The University of Texas Health Science Center at Houston, Houston

    Registry updated 2026-02-11

  • NCT06843252

    Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

    Trial Treatment · The University of Texas Health Science Center at San Antonio

    University of Texas Health Science Center at San Antonio, San Antonio

    Registry updated 2026-02-11

  • NCT03233646

    Retinal Imaging in Neurodegenerative Disease

    Research · Duke University

    Duke University Medical Center, Durham

    Registry updated 2026-02-04

  • NCT06828471

    Social Cognition Training in Individuals With Huntington's Disease

    Trial Treatment · Rush University Medical Center

    Rush University Medical Center, Chicago

    Registry updated 2025-12-10

  • NCT06475898

    Longitudinal Endpoint Assessment of Disease Burden in HD

    Research · Huntington Study Group

    Huntington Study Group, Rochester

    Registry updated 2025-09-10

  • NCT06448546

    Gut Microbiomes in HD

    Research · University of Central Florida

    University of Central Florida, Orlando

    Registry updated 2025-06-18

  • NCT06941662

    Huntington's Disease Biobank: Advancing Remote Monitoring and Deep Phenotyping

    Research · Stanford University

    Stanford University, Palo Alto

    Registry updated 2025-04-24

  • NCT06876857

    University of Central Florida CereBank

    Research · University of Central Florida

    University of Central Florida, Orlando

    Registry updated 2025-03-14

  • NCT06203106

    NYSCF Scientific Discovery Biobank

    Research · New York Stem Cell Foundation Research Institute

    New York Stem Cell Foundation Research Institute, New York

    Registry updated 2025-03-03

  • NCT06082713

    Extracellular Vesicles for HD

    Research · University of Central Florida

    University of Central Florida, Orlando

    Registry updated 2024-12-06

  • NCT01574053

    Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

    Research · CHDI Foundation, Inc.

    Albany Medical College, Albany · University of Michigan, Ann Arbor · Emory University, Wesley Woods Health Center, Atlanta · Georgia Health Sciences University, Augusta · University of Maryland School of Medicine, Baltimore · Johns Hopkins University, Baltimore · University of Alabama, Birmingham · Boston University Medical Center, Boston · Beth Israel Deaconess Medical Center, Boston · University of Vermont, Burlington · Cooper University Hospital, Camden · University of Virginia, Charlottesville · University of Chicago, Chicago · Northwestern University, Chicago · Rush University Medical Center, Chicago · University of Cincinatti, Cincinnati · Cleveland Clinic, Cleveland · University of South Carolina, Columbia · The Ohio State University, Columbus · Wayne State University, Detroit · Duke University, Durham · CenExel Rocky Mountain Clinical Research, LLC, Englewood · Sanford Health, Fargo · University of Connecticut, Farmington · University of Florida Board of Trustees, Gainesville · Virginia Commonwealth University Parkinson's and Movement Disorders Center, Henrico · University of Texas Health Science Center, Houston · Baylor College of Medicine, Houston · Indiana University, Indianapolis · University of Iowa, Iowa City · University of California, Irvine Medical Center, Irvine · University of Kansas Medical Center, Kansas City · Booth Gardner Parkinson's Care Center (Evergreen Health), Kirkland · Cleveland Clinic - Las Vegas, Las Vegas · Loma Linda Medical Center, Loma Linda · University of California, Los Angeles, Los Angeles · University of Louisville, Louisville · University of Wisconsin - Madison, Madison · University of Tennessee Health Science Center, Memphis · University of Miami, Miami · Hennepin County Medical Center, Minneapolis · Vanderbilt University Medical Center, Nashville · Rutgers, The State University of New Jersey, New Brunswick · Columbia University, New York · University of Nebraska Medical Center, Omaha · University of Pennsylvania, Philadelphia · St. Joseph's Hospital and Medical Center, Phoenix · University of Pittsburgh, Pittsburgh · Oregon Health and Science University, Portland · Virginia Commonwealth University, Richmond · University of Rochester, Rochester · University of Illinois College of Medicine at Rockford, Rockford · University of California - Davis, Sacramento · University of Utah, Salt Lake City · University of California San Diego, San Diego · University of California San Francisco, San Francisco · University of Washington Medical Center, Seattle · Washington University in St. Louis, St Louis · University of South Florida, HDSA Center of Excellence at USF, Tampa · Georgetown University, Washington D.C. · Hereditary Neurological Disease Center, Wichita · Wake Forest School of Medicine, Winston-Salem

    Registry updated 2024-02-28

All Huntington's disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

Huntington's disease trials in United States – Frontlight Research