High blood pressure trials in Canada

In Canada 28 Also abroad 865

24 of 28 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Calgary, Cambridge, Chicoutimi, Courtice, Halifax, Joliette, Kelowna, Laval, London, Mississauga, Moncton, Montreal, Newmarket, New Westminster, North Vancouver, Oshawa, Ottawa, Penticton, Peterborough, Québec, Red Deer, Saint-Lambert, Sarnia, Scarborough Village, Sherbrooke, Stoney Creek, Stouffville, Surrey, Terrebonne, Toronto, Trois-Rivières
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Taking people
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
Where
Brampton, Burlington, Cambridge, Chicoutimi, Edmonton, Etobicoke, Greater Sudbury, Laval, Lévis, London, Longueuil, Mirabel, Mississauga, Moncton, Montreal, Peterborough, Québec, Richmond, Rimouski, Saint-Jérôme, Sarnia, Scarborough, Sherbrooke, Sydney, Toronto, Trois-Rivières, Windsor
Age
18 years and over
People
11,000 worldwide
Run by
Alnylam Pharmaceuticals
See details and how to joinNCT07181109 · EU 2025-522960-34-00
Phase 3Taking people
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Where
Edmonton, Etobicoke, Halifax, Laval, London, Montreal, Oshawa, Québec, Saint John, Sarnia, Surrey, Toronto, Vancouver, Waterloo, Winnipeg
Age
18 years and over
People
5,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT06742723 · EU 2023-506460-14-00
Phase 3Not yet taking people in Canada
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
Where
Halifax, Hamilton, London, Moncton, Québec, Trois-Rivières, Vancouver, Victoria
Age
18 years and over
People
1,408 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07919405
No phaseNot yet taking people in Canada
Effects of Smartphone Use and Television Viewing on Standardized BP Measurement: The SCREENS-BP Study
Where
Montreal
Age
18 years and over
People
96 worldwide
Run by
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
See details and how to joinNCT07903779
No phaseTaking people
Renal Denervation in Patients With Atrial Fibrillation and Hypertension
Where
London
Age
18 years and over
People
10
Run by
Pavel Antiperovitch
See details and how to joinNCT07893821
Phase 4Not yet taking people in Canada
SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive Therapy
Where
Laval, Ottawa, Saint Isidore
Age
18 years and over
People
30
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT07687160
No phaseTaking people
Feasibility of a Community-Integrated Isometric Handgrip Exercise Program and Its Preliminary Effects on Blood Pressure and Cognitive Function in Older Adults
Where
Hamilton
Age
65 years and over
People
30
Run by
McMaster University
See details and how to joinNCT07648498
Phase 3Enrolling by invitation
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
Where
Calgary, Edmonton, London, Montreal, Québec, Toronto
Age
18 years and over
People
1,000 worldwide
Run by
United Therapeutics
See details and how to joinNCT03683186 · EU 2023-509305-68-00
No phaseNot yet taking people in Canada
Spinal Cord Stimulation for Blood Pressure Control in Hypertension
Where
Calgary
Age
18 years and over
People
11
Run by
University of Calgary
See details and how to joinNCT07842315
No phaseTaking people
Investigating the Combined Effects of Protein, Blueberries, and Exercise on Cardiovascular Health and Frailty in Older Nova Scotians
Where
Halifax
Age
65 years and over
People
240
Run by
Nova Scotia Health Authority
See details and how to joinNCT06693271
No phaseNot yet taking people in Canada
The BASIC-S Feasibility Study for Vascular Risk Reduction
Where
London
Age
18 years and over
People
120
Run by
Andrew Appleton
See details and how to joinNCT07755631
No phaseTaking people
Third Enhanced Control of Hypertension and Thrombectomy Stroke Domain Within ACT-GLOBAL Adaptive Platform Trial
Where
Calgary
Age
18 years and over
People
2,000 worldwide
Run by
The George Institute
See details and how to joinNCT06352619
No phaseTaking people
The SWITCH (Substitution of High With Low Ultra-processed Soy Protein Foods In a Guideline-based Diet inTervention for Cardiometabolic Health) Trial
Where
Toronto
Age
18 years and over
People
300
Run by
University of Toronto
See details and how to joinNCT06907862
Phase 1Taking people
Metabolic Imaging of the Heart Using Hyperpolarized (13C) Pyruvate Injection
Where
Toronto
Age
19 years to 75 years
People
112
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT02648009
No phaseTaking people
Implementation and Evaluation of a Pharmacist-led Diabetes Care Pathway in Alberta Community Pharmacies
Where
Edmonton
Age
18 years and over
People
600
Run by
University of Alberta
See details and how to joinNCT07339852
Early phase 1Taking people
Cognitive Behavioral Therapy and Trazodone Effects on Sleep and Blood Pressure in Insomnia
Where
Québec
Age
18 years and over
People
600 worldwide
Run by
Milton S. Hershey Medical Center
See details and how to joinNCT06281756
No phaseTaking people
Impact of Resistance Training Intensity on Blood Pressure
Where
Sherbrooke
Age
50 years to 70 years
People
36
Run by
Université de Sherbrooke
See details and how to joinNCT06845514
No phaseTaking people
Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women (PART II)
Where
Toronto
Age
18 years to 50 years
People
54
Run by
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
See details and how to joinNCT06655675
No phaseNot yet taking people in Canada
Postpartum CO Rehabilitation
Where
Montreal
Age
18 years and over
People
40
Run by
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
See details and how to joinNCT06920537
No phaseTaking people
Stretching vs Walking for Lowering Blood Pressure
Where
Saskatoon
Age
18 years and over
People
96
Run by
University of Saskatchewan
See details and how to joinNCT05252208
No phaseTaking people
Micro-doses of Physical Activity for COPD
Where
Kelowna
People
20
Run by
University of British Columbia
See details and how to joinNCT05553223
No phaseTaking people
Physical Activity Program for Reducing Blood Pressure in Sleep Apnea Patients With Resistant Hypertension
Where
Québec
Age
18 years to 80 years
People
100 worldwide
Run by
AGIR à Dom
See details and how to joinNCT02057783
No phaseNot yet taking people in Canada
SCORE! Non-Physician Health Worker (NPHW) Implementation Protocol (SIP)
Where
Hamilton
Age
18 years and over
People
137
Run by
Sonia Anand
See details and how to joinNCT06694987