High blood pressure trials in United States

In United States 312 Also abroad 843

312 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Chronic Hypertension and Pregnancy 2 (CHAP2) Pilot Project
Where
Birmingham
Age
14 years to 89 years
People
74
Run by
University of Alabama at Birmingham
See details and how to joinNCT05989581
No phaseEnrolling by invitation
Fixed-Dose Combinations Pragmatic Randomized Implementation Trial for Blood Pressure Control
Where
Milwaukee
Age
18 years to 80 years
People
720
Run by
Brigham and Women's Hospital
See details and how to joinNCT07228065
Phase 1/2Taking people
A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension
Where
Port Orange
Age
18 years to 75 years
People
69 worldwide
Run by
CRISPR Therapeutics AG
See details and how to joinNCT07758634
Phase 2Taking people
Xenon MRI Pulm Hypertension
Where
Durham
Age
18 years to 75 years
People
20
Run by
Bastiaan Driehuys
See details and how to joinNCT04991454
No phaseNot yet taking people in United States
Mobile Health Management of Hypertension
Where
Chicago
Age
18 years and over
People
40
Run by
University of Chicago
See details and how to joinNCT05856955
No phaseTaking people
Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension
Where
Atlanta, Detroit, Gainesville, Orange, Rochester, Stanford
Age
22 years to 80 years
People
15
Run by
DeepQure Inc.
See details and how to joinNCT06526858
Phase 3Taking people
Cardiovascular Protection After Preeclampsia With Enalapril
Where
Providence
Age
18 years and over
People
60
Run by
Women and Infants Hospital of Rhode Island
See details and how to joinNCT07222852
No phaseNot yet taking people in United States
Navigating Hypertension and Food Insecurity
Where
Honokaa, Waianae, Waimanalo
Age
20 years and over
People
250
Run by
University of Hawaii
See details and how to joinNCT07544836
Phase 1/2Taking people
Polypill for Prevention of Cardiomyopathy
Where
Dallas
Age
18 years to 100 years
People
200
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT06143566
No phaseTaking people
Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension Study
Where
Cleveland
Age
18 years and over
People
200
Run by
The Cleveland Clinic
See details and how to joinNCT07363343
No phaseTaking people
WEAVE NM: Heart Health and Nutrition for Life
Where
Albuquerque
Age
18 years to 84 years
People
240
Run by
University of New Mexico
See details and how to joinNCT07074145
Phase 2Taking people
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Where
Berlin, Brandon, Chicago, Edmond, Fayetteville, Ft. Washington, Garden Grove, Jefferson City, Los Angeles, Memphis, Miami, Miami Lakes, Monroe, Pembroke Pines, San Antonio, Tampa, Troy, Wellington, Wichita
Age
18 years and over
People
323 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07543120
Phase 2Taking people
A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
Where
Boca Raton, Brandon, Canton, Chicago, Cooper City, Coral Gables, Doral, Foley, Ft. Washington, Houston, Jacksonville, Lanham, Lincoln, Little River, Los Angeles, Manassas, Miami, Miami Lakes, Monroe, Niles, Northridge, Pembroke Pines, Richmond, Saint Augustine, Saraland, West Monroe, Wichita
Age
18 years to 75 years
People
120
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07610278
No phaseTaking people
Mobile Health Program for Post-Preeclampsia Hypertension
Where
Pittsburgh
Age
18 years and over
People
50
Run by
University of Pittsburgh
See details and how to joinNCT07599579
No phaseTaking people
A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
Where
Bowling Green, Chicago, Cleveland, Dallas, Houston, Pittsburgh, Plantation, Valley Village, Washington, West Hills
Age
22 years and over
People
160
Run by
Zona Health, Inc
See details and how to joinNCT06843577
No phaseTaking people
Behavioral Interventions Combining AI/ML and Personalized Medicine to Reduce Cardiovascular Risk - Randomized Controlled Trial
Where
La Jolla
Age
18 years and over
People
3,000
Run by
National Bureau of Economic Research, Inc.
See details and how to joinNCT07725250
No phaseTaking people
Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension
Where
Indianapolis
Age
35 years to 75 years
People
200
Run by
Indiana University
See details and how to joinNCT05856591
No phaseTaking people
MIND Foods and Aerobic Training in Black Adults With HTN
Where
Indianapolis
Age
35 years to 75 years
People
128
Run by
Indiana University
See details and how to joinNCT06152614
No phaseTaking people
Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
Where
Chicago, Milwaukee
Age
18 years and over
People
618
Run by
Medical College of Wisconsin
See details and how to joinNCT06220721
No phaseTaking people
Postpartum Preeclampsia Early Detection and Treatment: Nepal Pilot Study
Where
Milwaukee
Age
18 years and over
People
60 worldwide
Run by
Medical College of Wisconsin
See details and how to joinNCT07185204
No phaseTaking people
The RADIANCE CED Study
Where
Detroit
Age
65 years and over
People
1,000
Run by
ReCor Medical, Inc.
See details and how to joinNCT07231757
Phase 2Enrolling by invitation
Droxidopa / Pyridostigmine in Orthostatic Hypotension
Where
Rochester
Age
18 years and over
People
30
Run by
Mayo Clinic
See details and how to joinNCT01370512
No phaseNot yet taking people in United States
Optimizing Care For Management Of Hard To Control Hypertension In Low-Income Patients Across Family Health Centers In New York City
Where
New York
Age
18 years and over
People
628
Run by
NYU Langone Health
See details and how to joinNCT07703423
No phaseTaking people
Reach Out 2: Emergency Department-Initiated Hypertension Mobile Health Intervention Connecting Multiple Health Systems
Where
Flint
Age
18 years to 99 years
People
500
Run by
Northwestern University
See details and how to joinNCT06391073
No phaseTaking people
Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
Where
Boston
Age
18 years and over
People
1,320
Run by
Massachusetts General Hospital
See details and how to joinNCT06557005