Melanoma trials in United States

In United States 268 Also abroad 578

268 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors
Where
Bakersfield, Billings, Boston, Cincinnati, Fullerton, Los Angeles, Nashville, New York, Richmond, San Francisco, Scottsdale
Age
18 years and over
People
117
Run by
Georgiamune Inc
See details and how to joinNCT06425926
Phase 1Taking people
A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
56
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT05859074
Phase 1Not yet taking people in United States
Phase 1 Study Of Intrathecal Cellular Adoptive Immunotherapy Using Autologous CD8+ Antigen-Specific T Cells For Patients With Leptomeningeal Melanoma
Where
Houston
Age
18 years and over
People
8
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07414979
Phase 1/2Taking people
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Where
Bethesda, Boston, Celebration, Columbus, Detroit, Houston, Kansas City, Madison, Miami, Nashville, Sacramento, San Antonio, Seattle
Age
18 years and over
People
366 worldwide
Run by
Marengo Therapeutics, Inc.
See details and how to joinNCT05592626 · EU 2023-505334-10-01
Phase 2Taking people
Nodal Radiation Therapy for Sentinel Lymph Node Positive Melanoma
Where
Camden, Houston, Jacksonville
Age
18 years and over
People
168
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04594187
No phaseTaking people
Rural Adult and Youth Sun Protection Study
Where
Morgantown, Salt Lake City
Age
3 years to 7 years
People
843
Run by
University of Utah
See details and how to joinNCT06439979
No phaseTaking people
Digital Remote Monitoring of Immune Checkpoint Inhibitor Therapy Induced Toxicity Using the Vigilant App
Where
Rochester
Age
18 years and over
People
100
Run by
Mayo Clinic
See details and how to joinNCT06675643
Phase 1Taking people
IDOV-Immune for Advanced Solid Tumors
Where
Houston, San Antonio, St Louis
Age
18 years and over
People
78 worldwide
Run by
ViroMissile, Inc.
See details and how to joinNCT06910657
No phaseTaking people
Investigating Real-Time Immunotherapy Symptoms Study
Where
Pittsburgh
Age
18 years and over
People
40
Run by
University of Pittsburgh
See details and how to joinNCT07280715
Early phase 1Taking people
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
Where
Orange
Age
18 years and over
People
25
Run by
University of California, Irvine
See details and how to joinNCT07628634
Phase 1Taking people
Sitagliptin With Pembro in RCC and Melanoma
Where
Iowa City
Age
18 years to 99 years
People
64
Run by
Fernando Maciel Barbosa
See details and how to joinNCT07634380
No phaseTaking people
MySmartSkin Online Skin Self-exam Intervention for Melanoma Survivors
Where
New Brunswick
Age
18 years and over
People
385
Run by
Rutgers, The State University of New Jersey
See details and how to joinNCT05373823
No phaseTaking people
The Florida ASCENT Study
Where
Gainesville
Age
18 years to 100 years
People
100
Run by
University of Florida
See details and how to joinNCT07042243
Phase 1Taking people
Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer
Where
Seattle
Age
18 years and over
People
28
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT05098210
Phase 2Taking people
Palbociclib and Pembrolizumab In Central Nervous System Metastases
Where
Boston
Age
18 years and over
People
45
Run by
Massachusetts General Hospital
See details and how to joinNCT02896335
Phase 1/2Taking people
Tebentafusp-tebn With LDT in Metastatic UM
Where
Philadelphia
Age
18 years and over
People
109
Run by
Thomas Jefferson University
See details and how to joinNCT06626516
No phaseTaking people
Symptom Management and Survivorship Plus Coaching for Advanced Cancer Survivors and Their Caregivers
Where
Tucson
Age
18 years and over
People
200
Run by
University of Arizona
See details and how to joinNCT07415564
No phaseTaking people
Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia
Where
Dayton
Age
60 years and over
People
72
Run by
Wright State University
See details and how to joinNCT03906253
Phase 2Taking people
Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases
Where
Houston
Age
18 years and over
People
30
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT05704647
No phaseTaking people
The Preventive Role of Fractionated Laser Resurfacing Against Actinic Neoplasia in an At-Risk Geriatric Population
Where
Fairborn
Age
60 years and over
People
80
Run by
Wright State University
See details and how to joinNCT06428721
Phase 1Taking people
Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer
Where
Houston
Age
18 years and over
People
800
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT03819296
Phase 3Taking people
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]
Where
Atlanta, Aurora, Buffalo, Burlington, Camden, Chapel Hill, Chicago, Columbus, Dallas, Detroit, Durham, Englewood, Germantown, Gilbert, Grand Rapids, Hackensack, Hollywood, Houston, Iowa City, Jacksonville, Knoxville, La Jolla, Lake Success, Lebanon, Los Angeles, Louisville, Minneapolis, Morgantown, Morristown, Murray, Orange, Palo Alto, Park Ridge, Philadelphia, Pittsburgh, Providence, Sacramento, Salt Lake City, San Francisco, St. George, Stony Brook, Tampa, The Bronx, Washington D.C., Westwood
Age
12 years and over
People
400 worldwide
Run by
Replimune, Inc.
See details and how to joinNCT06264180 · EU 2023-508612-29-00
Early phase 1Not yet taking people in United States
Immune Checkpoint Inhibitor (ICI)-Drug-Drug Interaction (DDI) Study
Where
Indianapolis
Age
18 years and over
People
80
Run by
Indiana University
See details and how to joinNCT07389525
Phase 2Taking people
Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial
Where
Orange
Age
18 years and over
People
75
Run by
University of California, Irvine
See details and how to joinNCT06580002
Phase 1Taking people
Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma
Where
Columbus
Age
18 years to 99 years
People
36
Run by
Carlo Contreras
See details and how to joinNCT04697576