Multiple myeloma trials in United States

In United States 297 Also abroad 703

297 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseEnrolling by invitation
Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event
Where
Bethesda
Age
18 years to 120 years
People
136
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07499128
Phase 1/2Taking people
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
Where
Atlanta, Bethesda, Indianapolis, Omaha, Philadelphia
Age
18 years and over
People
250 worldwide
Run by
CellCentric Ltd.
See details and how to joinNCT04068597
Phase 2Not yet taking people in United States
ELDORADO: Elranatamab Versus Daratumumab in Combination With RVd Lite for Newly Diagnosed Transplant Ineligible/Deferred Multiple Myeloma
Where
Boston
Age
18 years and over
People
160
Run by
Massachusetts General Hospital
See details and how to joinNCT07247097
Phase 2Taking people
A Study of Elranatamab and Cyclophosphamide in People With Multiple Myeloma
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
26
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07454382
Phase 1Taking people
Personalized Autologous Transplant for Multiple Myeloma
Where
Atlanta, Chicago
Age
18 years and over
People
90
Run by
Emory University
See details and how to joinNCT04483206
No phaseNot yet taking people in United States
PET-Enabled Dual-Energy CT in Multiple Myeloma
Where
Sacramento
Age
18 years and over
People
45
Run by
University of California, Davis
See details and how to joinNCT07646873
No phaseTaking people
The Ambient Light Multiple Myeloma Study
Where
New York
Age
21 years and over
People
200
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT05737732
Phase 1Taking people
A Phase 1 With Extension Cohort, Single Arm, Single Center, Open Label Trial of Belantamab Mafodotin for the Treatment of High-Risk Smoldering Multiple Myeloma
Where
Houston
Age
18 years and over
People
30
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT05055063
Phase 1Taking people
A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma
Where
Rochester, Scottsdale
Age
18 years and over
People
99
Run by
Mayo Clinic
See details and how to joinNCT03017820
Phase 3Taking people
Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment
Where
Aberdeen, Aitkin, Albuquerque, Allentown, Alton, Anchorage, Ankeny, Ann Arbor, Antigo, Appleton, Arroyo Grande, Ashland, Aurora, Ballwin, Baltimore, Bardstown, Battle Creek, Baxter, Beavercreek, Bellingham, Bemidji, Bend, Bethlehem, Bettendorf, Bismarck, Bloomington, Boardman, Boiling Springs, Boise, Bolivar, Brainerd, Branson, Bremerton, Brighton, Burbank, Burnsville, Burr Ridge, Cambridge, Cameron Park, Canton, Cape Girardeau, Carbondale, Carmel, Carmichael, Caro, Carterville, Carthage, Cedar Rapids, Centerville, Centralia, Charleston, Chelsea, Chippewa Falls, Cincinnati, Clackamas, Clarkston, Clive, Colorado Springs, Conroe, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Creston, Crown Point, Danville, Dayton, Decatur, Deer River, Denver, Derby, Des Moines, Detroit, Detroit Lakes, Dixon, Duluth, Durango, Dyer, Easley, East China, East Stroudsburg, Eau Claire, Edina, Edmonds, Effingham, Elk Grove, Ely, Eureka, Everett, Exeter, Fairfield, Fargo, Farmington, Findlay, Flint, Fort Lauderdale, Fort Smith, Fosston, Franklin, Fridley, Fruitland, Galesburg, Garden City, Glastonbury, Grand Rapids, Great Bend, Greenville, Greenwich, Greer, Grosse Pointe Woods, Guilford, Hartford, Hayward, Hazleton, Hibbing, Hines, Hobart, Homer Glen, Houston, Indianapolis, International Falls, Iowa City, Issaquah, Jacksonville, Jamestown, Jefferson City, Joplin, Jupiter, Kalamazoo, Kansas City, Kearney, Kennewick, Kettering, Kewanee, Lacey, La Crosse, Ladysmith, Lakewood, Lansing, League City, Lewisburg, Lexington, Lincoln, Little Rock, Littleton, Livonia, London, Longmont, Longview, Macomb, Maple Grove, Maplewood, Marlette, Marshfield, Martinsville, Marysville, Mattoon, Maywood, Medford, Melrose Park, Merced, Meridian, Minneapolis, Minocqua, Missoula, Monticello, Moose Lake, Mount Sterling, Mount Vernon, Munster, Muskegon, Nampa, Napa, Neillsville, Newberg, New Haven, New Richmond, New Ulm, New York, Niles, North Haven, Norton Shores, O'Fallon, Oklahoma City, Omaha, Oregon City, Osage Beach, Ottawa, Papillion, Parker, Park Rapids, Pekin, Peoria, Peru, Phoenix, Pontiac, Portland, Princeton, Pueblo, Redmond, Reed City, Rhinelander, Rice Lake, Richmond, Rio Rancho, Robbinsdale, Rochester, Rocklin, Rolla, Sacramento, Saginaw, Sainte Genevieve, Saint Joseph, Saint Louis Park, Saint Paul, San Antonio, Sandstone, San Luis Obispo, Santa Maria, Santa Rosa, Scranton, Seattle, Sedro-Woolley, Seneca, Shakopee, Shelton, Sioux Falls, South Hill, Spooner, Springfield, Stamford, Sterling Heights, Stevens Point, Stillwater, St Louis, Sugar Land, Sullivan, Sunset Hills, Superior, Tawas City, Thief River Falls, Torrington, Traverse City, Troy, Truckee, Trumbull, Twin Falls, Urbana, Valparaiso, Vancouver, Virginia, Waconia, Walla Walla, Warren, Washington, Waterbury, Waterford, Wausau, West Branch, West Des Moines, Westerly, Weston, Wilkes-Barre, Willmar, Wisconsin Rapids, Woodbury, Woodland, Worthington, Wyoming, Yankton, Yelm, Yorkville, Youngstown, Ypsilanti
People
510
Run by
SWOG Cancer Research Network
See details and how to joinNCT05561387
No phaseTaking people
Low-Dose Radiotherapy in Treating Painful Bone Metastases in Patients With Multiple Myeloma
Where
Atlanta, Boston, Duarte, Los Angeles, Minneapolis, New York, Philadelphia
Age
18 years and over
People
100
Run by
University of Southern California
See details and how to joinNCT03858205
Phase 2Taking people
Impact of Budesonide on Incidence of ≥ Gr2 Diarrhea in Multiple Myeloma (MM) Patients Undergoing Autologous Stem Cell Transplant
Where
Salt Lake City
Age
18 years and over
People
120
Run by
University of Utah
See details and how to joinNCT05405387
Phase 2Taking people
Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma
Where
Birmingham, Chapel Hill, Cincinnati, Columbus, Dallas, Denver, Iowa City, Madison, Milwaukee, Nashville, Norfolk
Age
19 years and over
People
100
Run by
SCRI Development Innovations, LLC
See details and how to joinNCT06974786
Phase 1Taking people
Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody Efficacy in Multiple Myeloma
Where
Iowa City
Age
18 years and over
People
10
Run by
Christopher Strouse
See details and how to joinNCT07581704
Phase 2Taking people
Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
Where
Chapel Hill, Charlotte, Columbus, Durham, Wilmington
Age
18 years and over
People
50
Run by
UNC Lineberger Comprehensive Cancer Center
See details and how to joinNCT05145400
Phase 2Taking people
Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma
Where
Atlanta
Age
18 years and over
People
68
Run by
Emory University
See details and how to joinNCT04776395
Early phase 1Taking people
Loratadine for the Reduction of G-CSF Induced Bone Pain in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization
Where
New Brunswick
Age
18 years and over
People
70
Run by
Rutgers, The State University of New Jersey
See details and how to joinNCT04211259
No phaseTaking people
A Cognitive Training Intervention for Improving Cognitive and Neurological Outcomes in Patients Undergoing Treatment for Relapsed or Refractory Multiple Myeloma or B-cell Non-Hodgkin Lymphoma
Where
Columbus
Age
18 years and over
People
90
Run by
Ohio State University Comprehensive Cancer Center
See details and how to joinNCT07609030
No phaseTaking people
A Music Therapy Study for Blood Cancer Survivors With Cognitive Difficulties
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
60
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07052916
No phaseTaking people
Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies
Where
Houston
Age
18 years and over
People
100
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT05011045
Phase 1Taking people
Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma
Where
Beverly Hills, Denver, Hillsborough, New Brunswick, New York, Seattle, St Louis
Age
18 years and over
People
135 worldwide
Run by
AbbVie
See details and how to joinNCT06896916 · EU 2024-512146-41-00
Phase 1Taking people
DC/MM Fusion Vaccine With BCMA CAR-T in R/R MM
Where
Boston
Age
18 years and over
People
25
Run by
David Avigan
See details and how to joinNCT07377435
No phaseTaking people
Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome
Where
Boston, Brighton, Kalamazoo, Londonderry, Methuen, Milford, Weymouth
Age
18 years and over
People
10,000
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT02269592
Phase 1Taking people
A Phase 1 Study of Vaccination With Dendritic Cell (DC)/Multiple Myeloma (MM) Fusions in Combination With Elranatamab in Relapsed or Refractory Multiple Myeloma
Where
Boston
Age
18 years and over
People
25
Run by
David Avigan
See details and how to joinNCT06799026
Phase 2Not yet taking people in United States
Emapalumab Prophylaxis of Bispecific T-Cell Engagers (BiTEs) Associated CRS and ICANS
Where
Brooklyn, Manhattan, Mineola
Age
18 years and over
People
60
Run by
NYU Langone Health
See details and how to joinNCT07567014