Multiple sclerosis trials in United States

In United States 185 Also abroad 503

185 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in United States
Physical Activity Intervention for Individuals Newly Diagnosed With MS
Where
Chicago
Age
18 years and over
People
50
Run by
University of Illinois Chicago
See details and how to joinNCT07731659
No phaseTaking people
Single Arm Trial Identifying Barriers and Facilitators to Mindfulness Practice
Where
Seattle
Age
18 years and over
People
80
Run by
University of Washington
See details and how to joinNCT07573241
No phaseNot yet taking people in United States
Combating Age-related Failure of Myelination in Multiple Sclerosis: An Exploratory Study
Where
Seattle
Age
50 years to 70 years
People
14
Run by
University of Washington
See details and how to joinNCT07723599
No phaseNot yet taking people in United States
Effects of Powered Hip Flexion Device in Persons With Multiple Sclerosis
Where
Dayton
Age
18 years to 80 years
People
10
Run by
University of Dayton
See details and how to joinNCT07724093
No phaseTaking people
Ocrevus Zunovo for MS: Mixed Methods
Where
Chicago
Age
18 years and over
People
150
Run by
Northwestern University
See details and how to joinNCT07710105
Phase 2Taking people
Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype
Where
Ann Arbor
Age
18 years to 65 years
People
166
Run by
Tiffany J. Braley, MD, MS
See details and how to joinNCT05269628
Phase 2Enrolling by invitation
Effects of Antiviral Therapies on Epstein-Barr Virus Replication
Where
Boston
Age
18 years and over
People
50
Run by
Massachusetts General Hospital
See details and how to joinNCT05957913
No phaseTaking people
Exercise Rehabilitation Program in MS Who Use Wheelchairs as a Primary Mobility Device
Where
Chicago
Age
18 years and over
People
24
Run by
University of Illinois Chicago
See details and how to joinNCT06410261
No phaseTaking people
Functional Balance Intervention in Multiple Sclerosis
Where
Chicago
Age
18 years to 90 years
People
120
Run by
University of Illinois Chicago
See details and how to joinNCT06341023
No phaseEnrolling by invitation
Study to Investigate Vagus Nerve Stimulation Paired With Motor Task for Remyelination and Functional Recovery
Where
Aurora
Age
18 years to 70 years
People
70
Run by
University of Colorado, Denver
See details and how to joinNCT06641271
Phase 1/2Taking people
Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy
Where
San Francisco
Age
18 years to 55 years
People
74
Run by
University of California, San Francisco
See details and how to joinNCT05359653
Phase 2Taking people
Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)
Where
New York
Age
18 years to 65 years
People
170
Run by
NYU Langone Health
See details and how to joinNCT06901687
No phaseEnrolling by invitation
Home-based Spinal Cord Stimulation for Hand & Arm Function in MS
Where
Seattle
Age
18 years to 70 years
People
2
Run by
University of Washington
See details and how to joinNCT07673354
No phaseTaking people
Neurologic Stem Cell Treatment Study
Where
Coral Springs, Westport
Age
18 years and over
People
500 worldwide
Run by
MD Stem Cells
See details and how to joinNCT02795052
Early phase 1Taking people
Gait Adaptation Study
Where
Newark
Age
18 years to 80 years
People
30
Run by
Rutgers, The State University of New Jersey
See details and how to joinNCT07660601
No phaseTaking people
Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis
Where
Atlanta
Age
45 years to 89 years
People
64
Run by
Georgia State University
See details and how to joinNCT06919900
No phaseTaking people
Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders
Where
New York
Age
18 years and over
People
170
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT05982925
Phase 2Taking people
A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years
Where
Boston, Dallas, El Paso, Farmington Hills, Oklahoma City, Ozark, Plano, St Louis
Age
18 years to 55 years
People
180 worldwide
Run by
ModernaTX, Inc.
See details and how to joinNCT06735248 · EU 2024-517949-13-00
No phaseEnrolling by invitation
Retinal Atrophy and Neurofilament Light Chain in People With Multiple Sclerosis Taking Ofatumumab
Where
Baltimore
Age
18 years to 70 years
People
75
Run by
Johns Hopkins University
See details and how to joinNCT06167642
No phaseTaking people
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
Where
Rochester
Age
18 years to 85 years
People
147
Run by
Mayo Clinic
See details and how to joinNCT06788886
Phase 2Taking people
Solriamfetol for the Treatment of Multiple Sclerosis Fatigue
Where
Baltimore
Age
18 years to 60 years
People
46
Run by
Johns Hopkins University
See details and how to joinNCT06170970
No phaseNot yet taking people in United States
My MS Toolkit: An Internet-Based Depression Self-Management Program for Adults Living With Multiple Sclerosis
Where
Seattle
Age
18 years and over
People
110
Run by
University of Washington
See details and how to joinNCT07636434
Phase 2Taking people
Hyperpolarized Carbon Metabolic Imaging in Multiple Sclerosis
Where
San Francisco
Age
18 years and over
People
40
Run by
Ari Green
See details and how to joinNCT07510607
No phaseTaking people
Pathological Basis of MRI Signal Changes in Multiple Sclerosis
Where
Bethesda
Age
18 years to 120 years
People
250
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT02659956
Phase 1Taking people
Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy
Where
Bethesda
Age
18 years to 120 years
People
15
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT05849467