Multiple sclerosis trials in United States

In United States 186 Also abroad 506

186 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1Enrolling by invitation
Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis
Where
Dallas
Age
18 years and over
People
20
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT06261528
No phaseTaking people
Prospective Investigation of Multiple Sclerosis in the Three Rivers Region
Where
Pittsburgh
Age
7 years and over
People
7,500
Run by
University of Pittsburgh
See details and how to joinNCT02994121
No phaseNot yet taking people in United States
Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis
Where
Birmingham
Age
18 years to 45 years
People
30
Run by
University of Alabama at Birmingham
See details and how to joinNCT04768777
Phase 1Not yet taking people in United States
Senolytics for Secondary Progressive MS
Where
Columbus
Age
50 years to 85 years
People
30
Run by
Ohio State University
See details and how to joinNCT07270120
No phaseTaking people
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
Where
West Orange
Age
18 years to 75 years
People
10
Run by
Kessler Foundation
See details and how to joinNCT04855825
No phaseTaking people
A Study on the Safety of Ozanimod Exposure in Pregnant Women and Their Offspring
Where
Bethesda
People
1,182 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT05170126
No phaseTaking people
NARCOMS Registry: A Multiple Sclerosis Registry
Where
Dallas
Age
18 years and over
People
50,000
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT01018537
No phaseTaking people
Prepare the Mind: Can Coaching in Goal-directed Behaviour Increase the Success of Cognitive Rehabilitation in People With MS?
Where
Buffalo
Age
18 years to 65 years
People
126 worldwide
Run by
Universiteit Leiden
See details and how to joinNCT07225868
No phaseTaking people
"Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS
Where
San Francisco
Age
18 years and over
People
300
Run by
University of California, San Francisco
See details and how to joinNCT07222618
Phase 1Not yet taking people in United States
OER Glibenclamide for Neuropathic Pain in Multiple Sclerosis
Where
Baltimore
Age
18 years to 65 years
People
10
Run by
University of Maryland, Baltimore
See details and how to joinNCT07221799
No phaseTaking people
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
Where
Cleveland
Age
22 years to 75 years
People
14
Run by
Cionic, Inc.
See details and how to joinNCT05964829
Phase 4Taking people
Prospective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod
Where
Aurora, Cleveland, Las Vegas
Age
18 years and over
People
100
Run by
University of Colorado, Denver
See details and how to joinNCT06529406
No phaseNot yet taking people in United States
Assessing the Effects of Ongoing Ocrelizumab (OCR) Therapy on Fatigue and Cognition in Veterans With Multiple Sclerosis
Where
Detroit
Age
18 years to 75 years
People
30
Run by
Anza Memon
See details and how to joinNCT07181811
No phaseEnrolling by invitation
Physiological Effects of N-Acetyl Cysteine in Patients With Multiple Sclerosis
Where
Philadelphia
Age
18 years and over
People
55
Run by
Thomas Jefferson University
See details and how to joinNCT03032601
Phase 4Enrolling by invitation
Quality Improvement and Practice Based Research in Neurology Using the EMR
Where
Evanston
Age
18 years to 100 years
People
3,300
Run by
Endeavor Health
See details and how to joinNCT02670161
No phaseTaking people
An Individualized-health eLibrary App for People With Multiple Sclerosis
Where
Champaign
Age
18 years and over
People
60
Run by
University of Illinois at Urbana-Champaign
See details and how to joinNCT05124600
No phaseTaking people
Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension
Where
Boston
Age
18 years and over
People
80
Run by
University of Massachusetts, Boston
See details and how to joinNCT06554340
No phaseTaking people
Dry Needling in Multiple Sclerosis
Where
Kansas City
Age
18 years to 64 years
People
24
Run by
University of Kansas Medical Center
See details and how to joinNCT06394310
Phase 2Taking people
Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis
Where
Boston
Age
18 years to 75 years
People
55
Run by
Tiziana Life Sciences LTD
See details and how to joinNCT06890923
No phaseTaking people
Effects of Torso Weighting on Muscle Activation During Balance Tests in Individuals With and Without Multiple Sclerosis
Where
Saint Augustine
Age
18 years to 75 years
People
40
Run by
University of St. Augustine for Health Sciences
See details and how to joinNCT06981013
Phase 2Not yet taking people in United States
Study of NG01 Cell Therapy in Secondary Progressive Multiple Sclerosis
Where
Miami
Age
18 years to 65 years
People
45 worldwide
Run by
NeuroGenesis Ltd.
See details and how to joinNCT06961383
Phase 1/2Taking people
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Where
Jacksonville, San Francisco, Stanford
Age
18 years to 80 years
People
65
Run by
Ashvattha Therapeutics, Inc.
See details and how to joinNCT05395624
No phaseTaking people
NYSCF Scientific Discovery Biobank
Where
New York
Age
30 days and over
People
10,000
Run by
New York Stem Cell Foundation Research Institute
See details and how to joinNCT06203106
No phaseTaking people
Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community
Where
East Hanover
Age
19 years to 65 years
People
40
Run by
Kessler Foundation
See details and how to joinNCT06608797
No phaseTaking people
Reducing Fatigue in People With Multiple Sclerosis by Treatment With TENS
Where
Boulder
Age
18 years to 65 years
People
60
Run by
University of Colorado, Boulder
See details and how to joinNCT05500963