Multiple sclerosis trials in United States

In United States 185 Also abroad 503

185 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in United States
Effect of Acetominophen an Gait Fatigue in Multiple Sclerosis
Where
New York
Age
18 years to 65 years
People
20
Run by
Hunter College of City University of New York
See details and how to joinNCT07440446
No phaseTaking people
Factorial Optimization Trial to Test Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue
Where
Seattle
Age
18 years and over
People
112
Run by
University of Washington
See details and how to joinNCT06809192
Phase 2Taking people
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
Where
San Francisco
Age
18 years to 55 years
People
90
Run by
University of California, San Francisco
See details and how to joinNCT02521311
Phase 1/2Not yet taking people in United States
Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy
Where
San Francisco
Age
18 years to 55 years
People
44
Run by
University of California, San Francisco
See details and how to joinNCT06065670
No phaseNot yet taking people in United States
Exercise With and Without Cognitive Training
Where
Decatur
Age
55 years to 85 years
People
30
Run by
VA Office of Research and Development
See details and how to joinNCT07447115
Phase 1Taking people
A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell ( CAR-T) Therapy in Subjects With Non-relapsing and Progressive Forms of Multiple Sclerosis
Where
Palo Alto
Age
18 years to 65 years
People
12
Run by
Stanford University
See details and how to joinNCT06138132
No phaseTaking people
Blood Flow Restriction And Veterans With MS
Where
Aurora
Age
18 years to 75 years
People
58
Run by
VA Office of Research and Development
See details and how to joinNCT05433103
No phaseTaking people
Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS
Where
Chicago
Age
18 years to 75 years
People
22
Run by
Shirley Ryan AbilityLab
See details and how to joinNCT06390930
No phaseTaking people
Central Vein Sign in Multiple Sclerosis Extension Study
Where
Cleveland, Los Angeles, Philadelphia
Age
18 years to 65 years
People
40
Run by
The Cleveland Clinic
See details and how to joinNCT07424027
No phaseTaking people
Multiple Sclerosis Implementation Network (Registry)
Where
Austin, Cherry Hill, Houston
Age
18 years and over
People
2,000
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT07415824
No phaseTaking people
Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients
Where
Ann Arbor
Age
18 years and over
People
40
Run by
University of Michigan
See details and how to joinNCT07392879
Phase 2/3Taking people
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Where
Denver
Age
18 years and over
People
70 worldwide
Run by
Kyverna Therapeutics
See details and how to joinNCT07403188 · EU 2024-511198-31-00
No phaseEnrolling by invitation
CorEvitas Multiple Sclerosis (MS) Registry
Where
Waltham
Age
18 years and over
People
1,000
Run by
CorEvitas
See details and how to joinNCT03291756
Early phase 1Taking people
Effects of Ublituximab on Motor Functions in Multiple Sclerosis
Where
Atlanta
Age
18 years to 55 years
People
25
Run by
Georgia State University
See details and how to joinNCT06629428
No phaseTaking people
Retinal Imaging in Neurodegenerative Disease
Where
Durham
Age
18 years and over
People
2,000
Run by
Duke University
See details and how to joinNCT03233646
Phase 1/2Taking people
Molecular Imaging of NET Using [C-11]MRB-PET in MS
Where
Boston
Age
18 years to 60 years
People
19
Run by
Brigham and Women's Hospital
See details and how to joinNCT03207464
Phase 1/2Taking people
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
Where
Boston
Age
18 years to 85 years
People
250
Run by
Brigham and Women's Hospital
See details and how to joinNCT02649985
No phaseTaking people
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
Where
Delafield
Age
2 years and over
People
10,000
Run by
Brain Inflammation Collaborative
See details and how to joinNCT04806620
No phaseTaking people
Home Based Functional Balance Intervention for Multiple Sclerosis
Where
Chicago
Age
40 years to 90 years
People
75
Run by
University of Illinois Chicago
See details and how to joinNCT07355387
No phaseEnrolling by invitation
Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research
Where
San Francisco
Age
18 years and over
People
200,000
Run by
University of California, San Francisco
See details and how to joinNCT02402426
Early phase 1Taking people
Assessment of Synaptic Density in MS
Where
Boston
Age
18 years to 60 years
People
30
Run by
Brigham and Women's Hospital
See details and how to joinNCT04634994
No phaseEnrolling by invitation
Immune Profiles in Multiple Sclerosis (MS) Patients and Healthy Volunteers Through Thoracic Duct Cannulation
Where
Philadelphia
Age
18 years to 40 years
People
24
Run by
University of Pennsylvania
See details and how to joinNCT05162638
Phase 4Taking people
Glucose Consumption in MS Using [F-18]FDG-PET
Where
Boston
Age
18 years to 70 years
People
50
Run by
Brigham and Women's Hospital
See details and how to joinNCT07087106
Phase 1Enrolling by invitation
Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis
Where
Dallas
Age
18 years and over
People
20
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT06261528
No phaseTaking people
Prospective Investigation of Multiple Sclerosis in the Three Rivers Region
Where
Pittsburgh
Age
7 years and over
People
7,500
Run by
University of Pittsburgh
See details and how to joinNCT02994121