Obesity trials in United States

In United States 744 Also abroad 1939

744 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Pregnancy 24/7 Offspring Study
Where
Iowa City, Morgantown, Pittsburgh
Age
0 years to 47 years
People
800
Run by
Kara Whitaker
See details and how to joinNCT07172880
No phaseTaking people
Time Restricted Eating for WeIght LoSs MainTenance-2
Where
New York
Age
25 years to 65 years
People
110
Run by
NYU Langone Health
See details and how to joinNCT07190170
Phase 1Taking people
Comparing the Extent to Which Maridebart Cafraglutide is Made Available in the Body of Participants Living With Overweight or Obesity After Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA)
Where
Dallas, Daytona Beach, Hialeah, Knoxville, Lexington, Madison, Maitland, Montclair, Phoenix
Age
18 years to 70 years
People
180
Run by
Amgen
See details and how to joinNCT07908316
No phaseNot yet taking people in United States
Brain and Obesity Longitudinal Development: Neurobiological Mechanisms of Semaglutide Treatment of Adolescent Obesity
Where
Boston
Age
12 years to 15 years
People
12
Run by
Erin Mauney
See details and how to joinNCT07911046
No phaseNot yet taking people in United States
Puerto Rican Obesity Intervention for Men
Where
Milwaukee
Age
35 years and over
People
48
Run by
Medical College of Wisconsin
See details and how to joinNCT06440551
Phase 1/2Taking people
HS235 Study in Overweight and Obese Participants With Combined Pre and Post-Capillary Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction
Where
Dallas, Greenville, Kansas City
Age
18 years and over
People
126
Run by
35Pharma Inc., a GSK company
See details and how to joinNCT07123779
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Ames, Arlington, Bridgeport, Butte, Champaign, Chicago, Clearwater, Columbus, Cortland, Dothan, El Dorado, Escondido, Fargo, Houston, Huntsville, Jacksonville, Jefferson City, Jersey City, Kansas City, Kingsport, Las Vegas, Maumee, Memphis, Mesa, Owensboro, Philadelphia, Portland, Renton, Rochester, Rocky Mount, Salt Lake City, San Antonio, Seattle, Smithfield, Statesville, Stockbridge, Sugar Land, Troy, Tulsa, Waco, Wilmington
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
Phase 3Not yet taking people in United States
SYNCHRONIZE®-HERA: A Study to Test Whether Survodutide Helps Women Who Are Living With Overweight or Obesity and Are Going Through or Have Finished Menopause, to Lose Weight
Where
Birmingham, Bowie, Fort Lauderdale, Jacksonville, Mandeville, Merritt Island, Metairie, Morehead City, Northridge, Ocoee, Ogden, Orange, Riverview, Walnut Creek
Age
45 years to 65 years
People
600 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07850050 · EU 2026-527092-29-00
Phase 3Not yet taking people in United States
ELEVATE-LIVER: A Study to Test Whether Survodutide Helps Improve Heart Structure and Function in People With Overweight or Obesity and Fatty Liver Disease
Where
Albuquerque, Boston, Bristol, Dallas, Durham, Kansas City, Los Angeles, Oxnard, Pasadena, Peoria, Statesville, Summerville, Topeka, University Park, West Hills
Age
18 years and over
People
600 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07850063 · EU 2026-527091-88-00
No phaseTaking people
Diabetes and Heart Disease Risk in Blacks
Where
Bethesda
Age
18 years to 70 years
People
2,000
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT00001853
No phaseTaking people
Children s Growth and Behavior Study
Where
Bethesda
Age
8 years to 100 years
People
1,500
Run by
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
See details and how to joinNCT02390765
No phaseTaking people
Remote Approaches for Optimizing Weight Loss (Elevate Weight Loss Trial)
Where
Providence
Age
18 years and over
People
490
Run by
The Miriam Hospital
See details and how to joinNCT06875622
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
Albany, Altamonte Springs, Amarillo, Ann Arbor, Arlington, Asheville, Atlanta, Austin, Aventura, Baltimore, Baton Rouge, Beltsville, Beverly Hills, Birmingham, Bloomfield Township, Boca Raton, Bowie, Boynton Beach, Bradenton, Bridgewater, Conroe, Coral Gables, Covina, Covington, Dallas, Detroit, Dothan, Duncanville, Durham, Elkhart, El Paso, Fairhope, Falls Church, Grand Rapids, Hammond, Hazel Crest, Hialeah, Hollywood, Horsham, Houston, Humble, Huntington Beach, Huntsville, Indianapolis, Inglewood, Inverness, Jackson, Jacksonville, Kalispell, Kansas City, Largo, Lenexa, Lenoir, Lexington, Lincoln, Little Rock, Manassas, Mandeville, Mankato, Maplewood, Marlton, McKinney, Meridian, Milwaukee, Minneapolis, Munster, Newark, Newport Beach, New York, Northridge, Oak Ridge, Ocala, Oklahoma City, Omaha, Orange, Orlando, Ormond Beach, Peachtree City, Pembroke Pines, Pensacola, Phoenix, Pittsburgh, Plano, Pomona, Poughkeepsie, Powell, Puyallup, Rapid City, Richmond, Roanoke, Rochester Hills, Salem, San Diego, San Francisco, Santa Rosa, Sarasota, Sherman, Somerset, Southfield, Stamford, Staten Island, Statesville, Stockton, Tomball, Tucson, Tullahoma, Wellington, Wichita, Wilmington, Winter Park, Yuma
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
No phaseNot yet taking people in United States
Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online)
Where
Indianapolis
Age
12 years to 17 years
People
159
Run by
Indiana University
See details and how to joinNCT07856784
No phaseNot yet taking people in United States
The Sleep and Weight Study
Where
New York
Age
18 years to 55 years
People
40
Run by
NYU Langone Health
See details and how to joinNCT07904663
No phaseTaking people
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Where
Sioux Falls
People
20,000
Run by
Sanford Health
See details and how to joinNCT01793168
Phase 3Taking people
Vibegron for ENergy Thinking and Resilience in Aging
Where
Winston-Salem
Age
45 years to 75 years
People
40
Run by
Wake Forest University Health Sciences
See details and how to joinNCT06987383
No phaseTaking people
Healthy Living BEYOND Weight Study
Where
Dallas
Age
18 years and over
People
1,000,000
Run by
American Heart Association
See details and how to joinNCT07075341
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
Where
Ames, Bakersfield, Beltsville, Chicago, DeSoto, Doral, Eatontown, El Paso, Fairhope, Farmington Hills, Fayette, Fleming Island, Fort Lauderdale, Franklin, Gardena, Greensboro, Houston, Huntsville, Jackson, Kansas City, Knoxville, Lanham, Lenexa, Lincoln, Little Rock, Manassas, Melrose Park, Mesa, Midland, Mobile, Monroe, Newton, Norfolk, North Dartmouth, Oak Brook, Ocoee, Omaha, Oxon Hill, Pasadena, Phoenix, Rockville, San Antonio, Scottdale, Somerset, St Louis, Stow, Torrance, Tucson, Walnut Creek, Warren Township, Woodstock
Age
18 years and over
People
1,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784270
Phase 2Taking people
Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities
Where
Amarillo, Arlington, Austin, Bellaire, Blackfoot, Bristol, Butte, Chicago, Cincinnati, City of Saint Peters, Clearwater, Concord, Costa Mesa, Dallas, Danville, Fargo, Fayette, Fleming Island, Greenbrae, Greensboro, Houston, Huntington Park, Jacksonville, Knoxville, Lake Worth, Las Vegas, Longview, Los Angeles, Louisville, Margate, Mesquite, Miramar, Monroe, Morehead City, Nashville, New Bern, Newport News, New Port Richey, Orlando, Pelham, Port Orange, Renton, Richmond, Rochester, Rolling Hills Estates, Roswell, Round Rock, Santa Ana, Scottsdale, Spring Valley, The Villages, Tucson, Tustin, Walnut Creek, Weston, West Palm Beach, Wilmington
Age
18 years to 75 years
People
360 worldwide
Run by
AbbVie
See details and how to joinNCT07752979
Phase 3Not yet taking people in United States
SYNCHRONIZE®-START- A Study to Test Whether Survodutide Helps People Living With Overweight or Obesity Who do Not Have Diabetes to Lose Weight
Where
Macon, Riverview
Age
18 years and over
People
350
Run by
Boehringer Ingelheim
See details and how to joinNCT07855900 · EU 2026-527093-36-00
Phase 1/2Taking people
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
Where
Baltimore, Phoenix
Age
18 years to 75 years
People
400 worldwide
Run by
Wave Life Sciences USA, Inc.
See details and how to joinNCT06842186 · EU 2024-520203-41-00
No phaseTaking people
Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity
Where
Boston, Menlo Park, Phoenix
Age
18 years and over
People
300
Run by
Foundation for the National Institutes of Health
See details and how to joinNCT07776678
Phase 2Taking people
Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss
Where
Birmingham, Bradenton, Champaign, Doral, Farmington Hills, Gretna, Irving, Nashville, New York, Oceanside, Oklahoma City, Orlando, San Antonio, South Jordan, Sun City, Tempe, Tomball, Wilmington, Woodstock
Age
18 years to 75 years
People
220
Run by
Alveus Therapeutics, Inc.
See details and how to joinNCT07837973
Phase 4Not yet taking people in United States
Effects of Tirzepatide on Esophagogastric Junction Mechanics, Reflux Burden, and Gastric Physiology in Adults With Obesity
Where
Rochester
Age
18 years to 75 years
People
30
Run by
Mayo Clinic
See details and how to joinNCT07893457