Opioid use disorder trials in United States

In United States 229 Also abroad 254

229 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Deep Brain Stimulation Effects In Patients With Opioid Use Disorder
Where
Pittsburgh
Age
22 years to 65 years
People
3
Run by
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
See details and how to joinNCT04354077
No phaseNot yet taking people in United States
The ConCERN Intervention for Loved Ones of Those With Opioid Use Disorder
Where
Ann Arbor, Detroit
Age
18 years and over
People
700
Run by
University of Michigan
See details and how to joinNCT07795840
Phase 2Taking people
GLP-1R Agonist Treatment for Opioid Use Disorder
Where
Baltimore, Fall River, Harrisburg, New York
Age
18 years to 75 years
People
200
Run by
Milton S. Hershey Medical Center
See details and how to joinNCT06548490
No phaseTaking people
PRoducing Outcome Measures for OTP Quality Improvement
Where
Research Triangle Park
Age
18 years and over
People
4,500
Run by
RTI International
See details and how to joinNCT07214389
No phaseTaking people
EMS-Initiated Buprenorphine
Where
Camden, Minneapolis, Oakland
People
495
Run by
Yale University
See details and how to joinNCT07475728
No phaseNot yet taking people in United States
Deep Transcranial Magnetic Stimulation for Tobacco Cessation in Adults With Opioid Use Disorder
Where
Pittsburgh
Age
22 years to 70 years
People
12
Run by
Payel Roy
See details and how to joinNCT07770555
No phaseTaking people
Personalized Addiction Treatment enHancement
Where
Providence
Age
22 years and over
People
40
Run by
Rhode Island Hospital
See details and how to joinNCT07778394
Phase 2Taking people
Ketones for Opioid Craving
Where
Wernersville
Age
18 years to 75 years
People
50
Run by
University of Maryland, Baltimore
See details and how to joinNCT07128524
Phase 2Taking people
Evaluating Buspirone to Treat Opioid Withdrawal
Where
Baltimore
Age
18 years to 75 years
People
100
Run by
University of Maryland, Baltimore
See details and how to joinNCT05511909
No phaseTaking people
Evaluation of a Patient Decision Aid for Emergency Department Initiated Buprenorphine
Where
Charleston
Age
18 years and over
People
20
Run by
Medical University of South Carolina
See details and how to joinNCT07278518
No phaseTaking people
Cerebral Physiology of NOWS
Where
Indianapolis
Age
Up to 1 day
People
46
Run by
Indiana University
See details and how to joinNCT07610746
No phaseTaking people
Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment
Where
West Haven
Age
18 years and over
People
75
Run by
VA Office of Research and Development
See details and how to joinNCT06454903
No phaseTaking people
Social Functioning in Opioid Use Disorder
Where
Charleston
Age
18 years and over
People
230
Run by
Medical University of South Carolina
See details and how to joinNCT07044466
No phaseTaking people
Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder
Where
Buffalo, New York, Storrs
Age
18 years and over
People
318
Run by
NYU Langone Health
See details and how to joinNCT05675735
No phaseTaking people
Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment
Where
Birmingham
Age
18 years to 80 years
People
200
Run by
University of Alabama at Birmingham
See details and how to joinNCT06104280
Phase 2Taking people
Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder
Where
Cape Girardeau, Chicago, Greenville, Huntington, Jacksonville, Morgantown, Nashville, Salt Lake City, Tampa
Age
18 years and over
People
310
Run by
T. John Winhusen, PhD
See details and how to joinNCT06651177
No phaseTaking people
Project I Test: Implementing HIV Testing in Opioid Treatment Programs
Where
New York
Age
18 years and over
People
418
Run by
Columbia University
See details and how to joinNCT03135886
Phase 4Taking people
Assessing Optimal XRB Initiation Points in Jail
Where
Boston, New Brunswick, New York, Springfield
People
50
Run by
NYU Langone Health
See details and how to joinNCT06051890
No phaseTaking people
fMRI and Opioid Abstinence
Where
Hartford, New Haven
Age
18 years to 50 years
People
240
Run by
Yale University
See details and how to joinNCT06651333
No phaseTaking people
Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy
Where
Pittsburgh
Age
18 years and over
People
100
Run by
Ilana Hull
See details and how to joinNCT05942313
Phase 1Not yet taking people in United States
Psilocybin After Trauma Surgery for Pain
Where
Pittsburgh
Age
25 years to 65 years
People
70
Run by
Trent Emerick
See details and how to joinNCT07406828
No phaseTaking people
Vanderbilt Integrated Community TMS for Opioid Recovery
Where
Brentwood, Nashville
Age
18 years to 65 years
People
100
Run by
Vanderbilt University Medical Center
See details and how to joinNCT07457489
No phaseEnrolling by invitation
Workforce and System Change to Treat Adolescent Opioid Use Disorder Within Integrated Pediatric Primary Care
Where
Indianapolis
Age
12 years and over
People
400
Run by
Indiana University
See details and how to joinNCT06477848
Phase 3Taking people
High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)
Where
Newark
Age
18 years and over
People
140
Run by
Rutgers, The State University of New Jersey
See details and how to joinNCT05589181
Early phase 1Not yet taking people in United States
Pilot of Mailing Buprenorphine
Where
Charleston
Age
18 years and over
People
20
Run by
Medical University of South Carolina
See details and how to joinNCT07421102