Opioid use disorder trials in United States

In United States 229 Also abroad 254

229 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Sparrow Link Neuromodulation Device for Opioid Withdrawal Management in Hospitalized Adults With Opioid Use Disorder
Where
Pittsburgh
Age
18 years and over
People
50
Run by
Payel Roy
See details and how to joinNCT07079826
No phaseTaking people
TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD)
Where
Portland
Age
18 years and over
People
60
Run by
Washington State University
See details and how to joinNCT07171359
Phase 3Taking people
Standard Versus High Dose ED-Initiated Buprenorphine Induction
Where
Camden, Oakland, Portland, Salt Lake City, San Leandro
Age
18 years to 65 years
People
360
Run by
Yale University
See details and how to joinNCT06494904
No phaseTaking people
Longitudinal Neural Fingerprinting of Opioid-use Trajectories
Where
New Haven
Age
18 years to 50 years
People
10
Run by
Yale University
See details and how to joinNCT06207162
No phaseTaking people
Addressing Racial Disparities in Opioid Overdose Using Peer Recovery Coach Training and mHealth Platform
Where
New York
Age
18 years to 99 years
People
180
Run by
Friends Research Institute, Inc.
See details and how to joinNCT06573476
Phase 2/3Taking people
Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder
Where
New York, Rockville
Age
18 years to 65 years
People
180
Run by
New York State Psychiatric Institute
See details and how to joinNCT05011266
No phaseTaking people
Novel Telemedicine-Delivered Prolonged Exposure Therapy for Treating PTSD in Individuals With OUD
Where
Burlington
Age
18 years and over
People
135
Run by
University of Vermont
See details and how to joinNCT06288711
No phaseTaking people
Systems Analysis and Improvement to Optimize Opioid Use Disorder Care Quality and Continuity for Patients Exiting Jail
Where
Seattle
Age
18 years to 110 years
People
4,186
Run by
University of Washington
See details and how to joinNCT06593353
No phaseTaking people
Mapping Ibogaine Neural Dynamics in Opioid Use Disorder
Where
Irvine
Age
21 years to 70 years
People
20
Run by
University of California, Irvine
See details and how to joinNCT07226570
No phaseEnrolling by invitation
Neurocognitive Mechanisms Underlying Smartphone-Assisted Prevention of Relapse in Opioid Use Disorder
Where
Little Rock
Age
18 years and over
People
336
Run by
University of Arkansas
See details and how to joinNCT05336188
Phase 4Taking people
Injectable Buprenorphine in Prison: A Preference Trial
Where
Cranston
Age
18 years and over
People
60
Run by
Lifespan
See details and how to joinNCT06880718
No phaseTaking people
Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine
Where
Greenville
Age
21 years and over
People
90
Run by
Prisma Health-Upstate
See details and how to joinNCT07202039
Phase 4Taking people
Better Options for Chronic Cancer Pain
Where
Ann Arbor, Indianapolis
Age
18 years to 99 years
People
294
Run by
VA Office of Research and Development
See details and how to joinNCT06574009
No phaseTaking people
VA Transitional Pain Service Study
Where
Salt Lake City
Age
18 years and over
People
400
Run by
VA Office of Research and Development
See details and how to joinNCT06223503
No phaseTaking people
Overdose Recovery and Care Access (ORCA) Qualitative Stakeholder Interviews and County-level Data
Where
Seattle
Age
18 years and over
People
40,000
Run by
University of Washington
See details and how to joinNCT06768814
No phaseEnrolling by invitation
Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care
Where
Palo Alto
Age
18 years and over
People
720
Run by
Palo Alto Veterans Institute for Research
See details and how to joinNCT04356274
No phaseTaking people
Implementing Contingency Management for Stimulant Use in Specialty Addiction Treatment Organizations
Where
Chicago, Pawtucket, Providence, Rockford
Age
18 years and over
People
76
Run by
Northwestern University
See details and how to joinNCT05702021
No phaseTaking people
Building Retention and Initiation Through Delivery of Peer-Guided Evidence-Based Practices
Where
Greenville
Age
18 years and over
People
750
Run by
Prisma Health-Upstate
See details and how to joinNCT07541417
No phaseTaking people
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Where
New Haven
Age
18 years to 55 years
People
100
Run by
Yale University
See details and how to joinNCT01730781
No phaseTaking people
Peer Recovery to Improve Polysubstance Use and Mobile Telemedicine Retention
Where
Baltimore, College Park, Denton, Washington D.C.
Age
18 years and over
People
160
Run by
University of Maryland, College Park
See details and how to joinNCT05973838
No phaseNot yet taking people in United States
Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans
Where
Northport
Age
18 years and over
People
60
Run by
VA Office of Research and Development
See details and how to joinNCT06766331
Phase 1/2Taking people
Clinical Trials of Multivalent Opioid Vaccine Components
Where
Eatontown, New York
Age
18 years to 59 years
People
45
Run by
New York State Psychiatric Institute
See details and how to joinNCT04458545
No phaseNot yet taking people in United States
Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study
Where
San Bernardino
Age
18 years and over
People
54
Run by
Loma Linda University
See details and how to joinNCT07001371
No phaseTaking people
Technology-Enhanced Therapy vs. Medication Monitoring for Buprenorphine Retention in Pregnant Persons
Where
Charleston
Age
18 years to 45 years
People
37
Run by
Medical University of South Carolina
See details and how to joinNCT06999811
No phaseTaking people
PrEP and MOUD Rapid Access for Persons Who Inject Drugs: The CHORUS+ Study
Where
Boston
Age
18 years and over
People
284
Run by
Boston Medical Center
See details and how to joinNCT05769218