Parkinson disease: open trials in United States

• NCT07642908

  Striatal and Extra-Striatal Cholinergic Terminal Density in LRRK2-PD Mutation

  Research · University of Michigan

  University of Michigan, Ann Arbor

  Registry updated 2026-11-06

• NCT07923201

  Evaluating the Effect of the Zeen Mobility Device on Clinical Practicality, Safety, and Impact (Via Assessments of Walking, Standing Tolerance, Balance, Endurance, Effort, and Participation in Daily Tasks) in an Outpatient Rehabilitation Setting for Individuals With Mobility Impairments.

  Trial Treatment · Casa Colina Hospital and Centers for Healthcare

  Casa Colina Hospital and Centers for Healthcare, Pomona

  Registry updated 2026-11-06

• NCT00060541

  Evaluation and Treatment of Neurosurgical Disorders

  Research · National Institute of Neurological Disorders and Stroke (NINDS)

  National Institutes of Health Clinical Center, Bethesda

  Registry updated 2026-11-05

• NCT01581580

  Deep Brain Stimulation Surgery for Movement Disorders

  Trial Treatment · National Institute of Neurological Disorders and Stroke (NINDS)

  National Institutes of Health Clinical Center, Bethesda

  Registry updated 2026-11-05

• NCT06778135

  Neocortical Microarchitecture of Executive Function

  Trial Treatment · University of Colorado, Denver

  University of Colorado, Aurora

  Registry updated 2026-11-05

• NCT07174310

  A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

  Trial Treatment · Phase 3 · Hoffmann-La Roche

  University of New Mexico, Albuquerque · Dent Neurological Institute, Amherst · Asheville Neurology, Asheville · Grady Memorial Hospital, Atlanta · JEM Research LLC, Atlantis · University of Alabama at Birmingham, Birmingham · Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton · Massachusetts General Hospital, Boston · University of Vermont Medical Center, Burlington · NeuroCare Center, Canton · University of Virginia Health System, Charlottesville · Northwestern University Feinberg School of Medicine, Chicago · Cleveland Clinic, Cleveland · Parkinson's Research Centers of America - Long Island, Commack · Texas Neurology, PA, Dallas · Duke University Medical Center, Durham · Rocky Mountain Movement Disorders, Englewood · QUEST Research Institute, Farmington Hills · Neurology Center of North Orange County, Fullerton · Hawaii Pacific Neuroscience, Honolulu · University of Kansas Medical Center, Kansas City · K2 - Villages, Lady Lake · UC San Diego, La Jolla · Cleveland Clinic Lou Ruvo, Las Vegas · Keck School of Medicine of USC, Los Angeles · UCLA Neurology Outpatient Clinic, Los Angeles · K2 Medical Research - Maitland, Maitland · Veracity Neuroscience, Memphis · Baptist Hospital of Miami, Miami · West Virginia University, Morgantown · Vanderbilt University Medical Center, Nashville · Institute for Neurodegenerative Disorders, New Haven · Columbia University Medical Center, New York · Weill Cornell Medical College, New York · Advent Health Orlando, Orlando · Charter Research - Winter Park/Orlando, Orlando · Parkinson?s Research Centers of America ? Palo Alto, Palo Alto · Hackensack University Medical Center;Department of Neurology, Neuroscience Institute, Paramus · Profound Research LLC at The Neurology Center of Southern California, Pasadena · University Pennsylvania Hospital, Philadelphia · Barrow Neurological Institute, Phoenix · Allegheny General Hospital, Pittsburgh · Oregon Health and Science University, Portland · Renown Health, Reno · VCU Health North Hospital, Richmond · Central Texas Neurology Consultants, Round Rock · UCSF Weill Institute for Neurosciences, San Francisco · Avera Medical Group, Sioux Falls · Stanford Neuroscience Health Center (SNHC), Stanford · Washington Uni School of Medicine, St Louis · USF Parkinsons Disease and Movement Disorders Center, Tampa · The Movement Disorder Clinic of Oklahoma, Tulsa · Georgetown University, Washington D.C.

  Registry updated 2026-11-05

• NCT07399496

  Accelerated rTMS for Apathy in Parkinson's Disease

  Trial Treatment · Medical University of South Carolina

  Medical University of South Carolina, Charleston

  Registry updated 2026-11-05

• NCT07863180

  Tributyrin for Progressive Supranuclear Palsy (PSP): Virtual Trial

  Trial Treatment · Phase 1/2 · Prabesh Kanel

  Domino's Farms, Ann Arbor

  Registry updated 2026-11-05

• NCT07886879

  Parkinson's Disease in Type 1 Gaucher Disease

  Research · Icahn School of Medicine at Mount Sinai

  Icahn School of Medicine at Mount Sinai, New York

  Registry updated 2026-11-05

• NCT07428447

  Analysis of Cutaneous Phosphorylated Alpha-Synuclein to Identify Patients at Risk of Progressing From Essential Tremor to Parkinson's Disease

  Research · CND Life Sciences

  QUEST Research Institute, Farmington Hills · Baylor College of Medicine, Houston · University of California Irvine Health, Irvine · University of Kansas Medical Center, Kansas City · Cedars-Sinai Medical Center, Los Angeles · Norton Healthcare, Louisville · Veracity Neurosciences LLC, Memphis · Vanderbilt University Medical Center, Nashville · Neurology One, Orlando · CND Clinical Research Center, Scottsdale · Movement Disorders Center of Arizona, Scottsdale

  Registry updated 2026-11-04

• NCT07267065

  AAV2-hAADC for Parkinson's Disease (PDCS-01)

  Trial Treatment · Phase 1 · Russell Lonser

  The Ohio State University, Columbus

  Registry updated 2026-11-03

• NCT07534397

  Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current Stimulation

  Trial Treatment · The University of Texas at Dallas

  Callier Clinical Center, The University of Texas at Dallas, Richardson

  Registry updated 2026-11-03

• NCT07914387

  Stanford University Neurofiber Study

  Trial Treatment · Phase 1 · Stanford University

  Stanford University Neurosciences, Stanford

  Registry updated 2026-11-03

• NCT04396873

  PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

  Trial Treatment · Phase 1 · National Institute of Mental Health (NIMH)

  National Institutes of Health Clinical Center, Bethesda

  Registry updated 2026-11-02

• NCT06944522

  A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

  Trial Treatment · Phase 3 · BlueRock Therapeutics

  Michigan Clinical Research Unit - Neurology, Ann Arbor · University of Michigan Clinical Research Unit - Neurology, Ann Arbor · University of Colorado Hospital - Neurology Clinic, Aurora · Johns Hopkins Hospital - Neurology, Baltimore · Beth Israel Deaconess Medical Center, Boston · Tufts Medical Center - Neurology, Boston · UBMD Neurology, Buffalo · University of Vermont Medical Center, Burlington · Medical University of South Carolina, Movement Disorders Dept., Charleston · Parkinson's Disease and Movement Disorders Center at Northwestern Memorial Hospital, Chicago · Rush University Medical Center - Neurology, Chicago · Duke Neurological Disorders Clinic, Durham · QUEST Research Institute, Farmington Hills · UTHealth Houston Neurosciences - Texas Medical Center, Houston · Mayo Clinic Jacksonville - Neurology, Jacksonville · University of Kansas Medical Center, Kansas City · EvergreenHealth - Research Department, Kirkland · University of Arkansas for Medical Sciences, Little Rock · UCLA NeuroTranslational Research Center, Los Angeles · University of Louisville Hospital, Louisville · University of Miami Health System - Neurology, Miami · Vanderbilt University Medical Center, Nashville · Mount Sinai West - Neurology, New York · New York - Presbyterian - Weill Cornell Medical Center, New York · UCI Medical Center - Neurology, Orange · Stanford Neuroscience Health Center, Palo Alto · OHSU Neurology Clinic, South Waterfront, Portland · Rhode Island Hospital - Neurology, Providence · Virginia Commonwealth University, Richmond · Mayo Clinic Scottsdale - Neurology, Scottsdale · Banner Sun Health Research Institute, Sun City · USF Parkinson's Disease and Movement Disorders Center, Tampa · University of Toledo Medical Center, Toledo · MedStar Georgetown University Hospital, Washington D.C.

  Registry updated 2026-11-02

• NCT06680830

  A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

  Trial Treatment · Phase 2 · Neuron23 Inc.

  University of New Mexico, Albuquerque · Emory University, Atlanta · Augusta University, Augusta · University of Colorado Anschutz Medical Campus, Aurora · University of Maryland, Baltimore · Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton · Beth Israel Deaconess Medical Center, Boston · University of North Carolina, Chapel Hill, Chapel Hill · Medical University of South Carolina, Charleston · University of Virginia, Charlottesville · Northwestern Medical Group, Department of Neurology, Chicago · The Ohio State University, Columbus · Neurology Consultants of Dallas, PA, Dallas · QUEST Research Institute, Farmington Hills · Neuro-Pain Medical Center, Fresno · University of Florida, Gainesville · Struthers Parkinson Center, Golden Valley · The University of Texas Health Science Center at Houston, Houston · Baylor College of Medicine, Houston · University of California, Irvine, Irvine · University of Kansas Medical Center, Kansas City · EvergreenHealth, Kirkland · Cleveland Clinic, Las Vegas · University of Kentucky, Lexington · University of Arkansas, Little Rock · University of California, Los Angeles, Los Angeles · Northwell Health, Manhasset · Medical College of Wisconsin, Milwaukee · Esperanza Clinical, Murrieta · Vanderbilt University, Nashville · Ochsner Clinic Foundation, New Orleans · Icahn School of Medicine at Mount Sinai/Mount Sinai West, New York · Columbia University, New York · Neurology One, Orlando · Parkinson?s Research Centers of America ? Palo Alto, Palo Alto · Thomas Jefferson University Hospital, Philadelphia · Oregon Health & Science University (OHSU), Portland · University of Rochester, Rochester · Central Texas Neurology Consultants, Round Rock · Sutter Neuroscience Institute, Sacramento · University of Utah Movement Division, Salt Lake City · Inland Northwest Research, Spokane · Banner Sun Health Research Institute, Sun City · USF Parkinson's & Movement Disorders Clinic, Tampa · The Movement Disorder Clinic of Oklahoma, Tulsa

  Registry updated 2026-10-30

• NCT06996652

  An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

  Trial Treatment · Phase 2 · Yale University

  Emory University School of Medicine, Atlanta · University of Colorado Anschutz, Aurora · Johns Hopkins University, Baltimore · Parkinson's Disease & Movement Disorders Center of Boca Raton, Boca Raton · Beth Israel Deaconess Medical Center, Boston · Massachusetts General Hospital, Boston · Medical University of South Carolina, Charleston · Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, Las Vegas · Dartmouth Hitchcock Medical Center, Lebanon · Cedars-Sinai Medical Center, Los Angeles · University of Minnesota, Minneapolis · Weill Medical College of Cornell University, New York · Yale Medicine, North Haven · University of Pennsylvania, Philadelphia · Oregon Health Science University, Portland · University of Texas Health Science Center San Antonio, San Antonio · Washington University, St Louis

  Registry updated 2026-10-30

• NCT07284784

  A Study of Buntanetap in Participants With PD

  Trial Treatment · Phase 2/3 · Annovis Bio Inc.

  First Choice Neurology - Aventura Neurologic Associates, Aventura · University of Alabama at Birmingham, Birmingham · Medical University of South Carolina (MUSC) - The Murray Center for Research on Parkinson's Disease, Charleston · University of Virginia Health System (UVAHS) - Adult Neurology Clinic, Charlottesville · The Ohio State University -Wexner Medical Center, Columbus · Neurology Clinic, P.C., Cordova · Arrow Clinical Trials, Daytona Beach · iResearch Atlanta, Decatur · Accel Clinical Sites-Georgia LLC dba Accel Research Sites-Lake Oconee CRU, DeLand · Duke Department of Neurosurgery, Durham · CenExel Rocky Mountain Clinical Research, Englewood · QUEST Research Institute, Farmington Hills · Parkinson's & Movement Disorder Institute (PMDI) - Orange County Office, Fountain Valley · Josephson Wallack Munshower Neurology P.C., Indianapolis · University of Kansas Medical Center (KUMC) - School of Medicine - Parkinson's Disease and Movement D, Kansas City · Veracity Neuroscience LLC, Memphis · Ezy Medical Research Co., Miami · Professional Research Center, Miami · Medical College of Wisconsin, Milwaukee · Mount Sinai Hospital, New York · Renstar Medical Research, Ocala · Central Texas Neurology, Round Rock · Inland Northwest Research, Spokane · New England Institute for Clinical Research (Ki Health Partners), Stamford · Banner Sun Health Research Institute - Cleo Roberts Center for Clinical Research, Sun City · University of South Florida (USF) - University of South Florida College of Medicine - Parkinson's Di, Tampa · The Movement Disorder Clinic of Oklahoma, Tulsa · Abington Neurology, Willow Grove · Conquest Research, Winter Park

  Registry updated 2026-10-30

• NCT07808346

  Investigating Basal Ganglia-Cortical Physiology During Sleep and Its Modulation by Adaptive Deep Brain Stimulation in Parkinson Disease

  Trial Treatment · University of Colorado, Denver

  University of Colorado, Aurora

  Registry updated 2026-10-30

• NCT00001215

  Genetic Studies of Lysosomal Storage Disorders

  Research · National Human Genome Research Institute (NHGRI)

  National Institutes of Health Clinical Center, Bethesda

  Registry updated 2026-10-29

• NCT07215403

  Open-Label, Multi-Stage Study to Optimize the Intraputaminal Administration of AB-1005 Using a Prescriptive Infusion Algorithm (PIA)

  Trial Treatment · Phase 2 · AskBio Inc

  Medical University of South Carolina, Charleston · University Hospitals Cleveland Medical Center*, Cleveland · The Ohio State University Wexner Medical Center Neurological Surgery, Columbus · University of Pittsburgh Medical Center, Pittsburgh

  Registry updated 2026-10-29

• NCT07432958

  A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations

  Trial Treatment · Phase 2 · Appello Pharmaceuticals, Inc.

  University of New Mexico Health Sciences Center (Site #225), Albuquerque · University of Michigan Health System (UMHS) (Site #202), Ann Arbor · Asheville Neurology Specialists, P.A. (Site #229), Asheville · Augusta University Medical Center (Site #212), Augusta · UM-UHealth at Boca Raton (Site #226), Boca Raton · Parkinson's Disease & Movement Disorders Center of Boca Raton (Site #227), Boca Raton · Beth Israel Deaconess Medical Center (Site #211), Boston · Profound Research LLC (Site #222), Carlsbad · Cleveland Clinic (Site #223), Cleveland · The Ohio State University Wexner Medical Center (site #207), Columbus · Horizon Clinical Research: Gill Neuroscience - Houston (Site #232), Cypress · Duke Neurological Disorders Clinic (Site #210), Durham · Rocky Mountain Clinical Research - CenExel - PPDS (Site #215), Englewood · Quest Research Institute - Alcanza - PPDS (Site #201), Farmington Hills · Velocity Clinical Research - Hallandale Beach (Site #228), Hallandale · Josephson Wallack Munshower Neurology PC (Site #231), Indianapolis · The University of Kansas (KU) (Site #216), Kansas City · EvergreenHealth (Site #219), Kirkland · Kentucky Neuroscience Institute (Site #213), Lexington · University of Arkansas for Medical Sciences (Site #208), Little Rock · Collaborative Neuroscience Network - Los Alamitos- CenExel - PPDS (Site #217), Los Alamitos · Keck Medicine of USC - USC Healthcare Center 2 (Site #221), Los Angeles · University of Miami (Site #220), Miami · Vanderbilt University Medical Center (Site #204), Nashville · Joan and Sanford I. Weill Department of Medicine (Site #224), New York · Mount Sinai School of Medicine (Site #209), New York · Neurology One (Site #205), Orlando · Parkinson's Research Centers of America (Site #218), Palo Alto · Central Texas Neurology Consultants (Site #203), Round Rock · USF Parkinson's Disease and Movement Disorders Center (Site #206), Tampa

  Registry updated 2026-10-28

• NCT07187466

  Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease

  Trial Treatment · Phase 4 · VA Office of Research and Development

  Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur · Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia · VA Salt Lake City Health Care System, Salt Lake City, UT, Salt Lake City

  Registry updated 2026-10-27

• NCT07804615

  A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy

  Trial Treatment · Phase 2 · Vima Therapeutics

  Albuquerque · Altamonte Springs · Amherst · Arlington · Atlanta · Aventura · Baltimore · Canton · Cypress · Dallas · Decatur · Farmington Hills · Kirkland · Memphis · Miami · Murrieta · Naples · New York · Olney · Overland Park · Palm Beach · Patchogue · Raleigh · Round Rock · Scottsdale · Scottsdale · Spokane · Stamford · Tampa

  Registry updated 2026-10-27

• NCT06442033

  Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial

  Trial Treatment · Jay Alberts

  The Cleveland Clinic, Cleveland

  Registry updated 2026-10-26

All Parkinson disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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