Parkinson disease trials in United States

In United States 294 Also abroad 823

294 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseEnrolling by invitation
Genetic Studies of Lysosomal Storage Disorders
Where
Bethesda
Age
1 week to 110 years
People
1,000
Run by
National Human Genome Research Institute (NHGRI)
See details and how to joinNCT00001215
Phase 2Not yet taking people in United States
Open-Label, Multi-Stage Study to Optimize the Intraputaminal Administration of AB-1005 Using a Prescriptive Infusion Algorithm (PIA)
Where
Charleston, Cleveland, Columbus, Pittsburgh
Age
45 years to 75 years
People
18
Run by
AskBio Inc
See details and how to joinNCT07215403
Phase 2Taking people
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
Where
Albuquerque, Ann Arbor, Asheville, Augusta, Boca Raton, Boston, Carlsbad, Cleveland, Columbus, Cypress, Durham, Englewood, Farmington Hills, Hallandale, Indianapolis, Kansas City, Kirkland, Lexington, Little Rock, Los Alamitos, Los Angeles, Miami, Nashville, New York, Orlando, Palo Alto, Round Rock, Tampa
Age
30 years to 80 years
People
150
Run by
Appello Pharmaceuticals, Inc.
See details and how to joinNCT07432958
Phase 4Not yet taking people in United States
Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease
Where
Decatur, Philadelphia, Salt Lake City
Age
18 years and over
People
146
Run by
VA Office of Research and Development
See details and how to joinNCT07187466
No phaseTaking people
Genetics and Aerobic Exercise to Slow Parkinson's Disease Trial
Where
Cleveland
Age
18 years and over
People
200
Run by
Jay Alberts
See details and how to joinNCT06442033
Phase 1/2Enrolling by invitation
Lithium for Parkinson's: an Extension Trial
Where
Williamsville
Age
45 years to 80 years
People
35
Run by
State University of New York at Buffalo
See details and how to joinNCT06592014
Phase 2Taking people
Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS
Where
Cleveland
Age
18 years and over
People
36
Run by
The Cleveland Clinic
See details and how to joinNCT07442747
No phaseTaking people
Investigating the Increased Risk of Falls in Individuals With Parkinson's Disease Treated With Deep Brain Stimulation
Where
Homewood
Age
30 years to 80 years
People
20
Run by
University of Alabama at Birmingham
See details and how to joinNCT07725315
No phaseTaking people
Decoding the Neural Mechanisms Underlying Postural Instability and Gait Dysfunction in Parkinson's Disease
Where
Cleveland
Age
18 years and over
People
5
Run by
The Cleveland Clinic
See details and how to joinNCT07748962
Phase 2/3Taking people
A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease
Where
Albany, Atlantis, Aurora, Bellevue, Birmingham, Boca Raton, Boston, Chesterfield, Chicago, Cleveland, Farmington, Farmington Hills, Foxborough, Henrico, Irvine, Kansas City, Los Angeles, Maitland, New Haven, Newport News, New York, Portland, Round Rock, Seattle, Sun City
Age
40 years to 80 years
People
550 worldwide
Run by
Biohaven Therapeutics Ltd.
See details and how to joinNCT06976268 · EU 2025-521113-13-00
Phase 1/2Taking people
A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease
Where
La Jolla, Lexington, New York
Age
40 years to 72 years
People
25
Run by
Sumitomo Pharma America, Inc.
See details and how to joinNCT06753331
No phaseNot yet taking people in United States
Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)
Where
Ann Arbor
Age
45 years to 90 years
People
20
Run by
University of Michigan
See details and how to joinNCT05509842
No phaseTaking people
Stimulus-Evoked Directional Field Potentials to Guide Subthalamic and Pallidal DBS for PD
Where
Birmingham
Age
18 years to 89 years
People
36
Run by
University of Alabama at Birmingham
See details and how to joinNCT06169852
No phaseTaking people
Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease
Where
Minneapolis
Age
21 years to 76 years
People
75
Run by
University of Minnesota
See details and how to joinNCT07226284
No phaseTaking people
EXercise-induced PhysioLogical Adaptations In Neurological Disorders
Where
Boston
Age
18 years and over
People
240
Run by
Brigham and Women's Hospital
See details and how to joinNCT07883720
Phase 1Taking people
MK-0947 PN-002: An Open-label Study to Evaluate Brain α-synuclein Deposition Using Positron Emission Tomography (PET) and [¹⁸F]MK-0947 in Participants With Parkinson's Disease (PD)
Where
New Haven
Age
40 years to 80 years
People
18
Run by
XingImaging, LLC
See details and how to joinNCT07880379
No phaseTaking people
Deep Brain Stimulation Therapy in Movement Disorders
Where
Bethesda
Age
18 years to 100 years
People
300
Run by
National Institute of Neurological Disorders and Stroke (NINDS)
See details and how to joinNCT02119611
Phase 1Taking people
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for Parkinson's Disease
Where
Naples
People
20 worldwide
Run by
The Foundation for Orthopaedics and Regenerative Medicine
See details and how to joinNCT05152394
Phase 1Taking people
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease
Where
Austin, Chicago, Englewood, Farmington Hills, Naples, New Haven, Philadelphia
Age
30 years to 80 years
People
124 worldwide
Run by
Prevail Therapeutics
See details and how to joinNCT06565195 · EU 2024-513411-27-00
Phase 2Taking people
Wearable Biofeedback for Swallowing Disorders Rehabilitation in Stroke and Parkinson Disease
Where
Champaign, West Lafayette
Age
50 years to 90 years
People
120
Run by
University of Illinois at Urbana-Champaign
See details and how to joinNCT06638944
No phaseTaking people
Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease
Where
Columbus
Age
18 years and over
People
76
Run by
Douglas Scharre
See details and how to joinNCT03019757
No phaseEnrolling by invitation
Quantification of Parkinson's Disease Patients as a Biomarker for Classification, Prediction and Response to Treatment
Where
Manchester
Age
18 years and over
People
40
Run by
Stardots AB
See details and how to joinNCT06586320
No phaseTaking people
Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage
Where
Rochester
Age
50 years and over
People
600 worldwide
Run by
Radboud University Medical Center
See details and how to joinNCT06993142
Phase 4Taking people
BOOST-PD A Naturalistic Study on IPX-203 for Parkinson's Disease
Where
Cleveland
Age
40 years and over
People
22
Run by
The Cleveland Clinic
See details and how to joinNCT07138560
Phase 1Taking people
A Study of LY4006896 in Healthy Participants and Participants With Parkinson's Disease
Where
Austin, Farmington Hills, Kirkland, Los Alamitos, Maitland, Naples, Orlando, Port Orange, Spokane, The Villages
Age
30 years to 85 years
People
90 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06809400