Sarcoma trials in United States

In United States 300 Also abroad 605

300 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma
Where
Houston
Age
10 years and over
People
20
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04199026
Phase 1/2Taking people
SPEARHEAD-3 Pediatric Study
Where
Bethesda, Boston, Cincinnati, Durham, Madison, New York, Palo Alto, Philadelphia, Seattle, St Louis
Age
2 years to 21 years
People
20
Run by
USWM CT, LLC
See details and how to joinNCT05642455
Phase 3Taking people
A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
Where
Columbus, Durham, Farmington Hills, Los Angeles, New Haven, Omaha, Philadelphia, Santa Monica
Age
18 years and over
People
333 worldwide
Run by
Intensity Therapeutics, Inc.
See details and how to joinNCT06263231 · EU 2024-512423-36-00
Phase 1/2Taking people
Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor
Where
Cleveland
Age
12 years and over
People
17
Run by
Ankit Mangla, MD
See details and how to joinNCT07549022
No phaseTaking people
Molecular Basis of Pediatric Liver Cancer
Where
Pittsburgh
Age
0 years to 99 years
People
1,600
Run by
University of Pittsburgh
See details and how to joinNCT03959800
No phaseTaking people
International Rare Brain Tumor Registry
Where
Akron, Chicago, Cincinnati, Los Angeles, San Francisco, Washington D.C.
Age
Up to 45 years
People
5,800 worldwide
Run by
Children's National Research Institute
See details and how to joinNCT05697874
Phase 1Taking people
Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors
Where
Houston
Age
1 year to 21 years
People
24
Run by
Baylor College of Medicine
See details and how to joinNCT04715191
Phase 1Taking people
Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas
Where
Cleveland
Age
18 years and over
People
24
Run by
Case Comprehensive Cancer Center
See details and how to joinNCT05210374
No phaseTaking people
Musculoskeletal Cancers Remote Monitoring and Care
Where
Cleveland
Age
18 years and over
People
60
Run by
Case Comprehensive Cancer Center
See details and how to joinNCT07129226
Phase 1Taking people
A Phase I Study of Pazopanib in Combination With Trabectedin, Ipilimumab and Nivolumab (TraPIN) in Pediatric and Young Adult Patients With Recurrent Soft Tissue Sarcomas
Where
Houston
Age
1 year to 30 years
People
18
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07444619
Phase 1Taking people
IDOV-Immune for Advanced Solid Tumors
Where
Houston, San Antonio, St Louis
Age
18 years and over
People
78 worldwide
Run by
ViroMissile, Inc.
See details and how to joinNCT06910657
No phaseEnrolling by invitation
A Study Involving Collection of Samples and Data From Sarcoma Patients Receiving Immunotherapy
Where
Basking Ridge, Commack, East White Plains, Middletown, Montvale, New York, Uniondale
People
250
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT06113315
No phaseTaking people
Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma
Where
Rochester
Age
18 years and over
People
75
Run by
Mayo Clinic
See details and how to joinNCT06409013
Phase 1/2Taking people
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
Where
Atlanta, Baton Rouge, Boston, Chicago, Cincinnati, Memphis, St Louis
Age
Up to 30 years
People
139
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT06239272
Phase 1/2Taking people
Proton or Photon RT for Retroperitoneal Sarcomas
Where
Boston, Buffalo, Chicago, Creve Coeur, Durham, Houston, Rochester, Salt Lake City, St Louis
Age
18 years and over
People
80
Run by
Massachusetts General Hospital
See details and how to joinNCT01659203
Early phase 1Taking people
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
Where
Orange
Age
18 years and over
People
25
Run by
University of California, Irvine
See details and how to joinNCT07628634
Phase 1Taking people
A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy
Where
Houston
Age
18 years and over
People
15
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07633756
No phaseTaking people
Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
People
3,000
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT00579566
Phase 1Taking people
Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1
Where
Houston
Age
16 years to 80 years
People
44
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT06083883
Phase 2Taking people
Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration
Where
Iowa City, Jacksonville, Milwaukee, St Louis
Age
18 years and over
People
44
Run by
Medical College of Wisconsin
See details and how to joinNCT04040205
Phase 2Taking people
A Study of Pembrolizumab in People With Ultra-Rare Sarcomas
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
32
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07089992
Phase 1/2Taking people
Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST
Where
Dallas, Washington D.C.
Age
18 years and over
People
45
Run by
AeRang Kim
See details and how to joinNCT06735820
Phase 2Taking people
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Where
Charlotte, Winston-Salem
Age
18 years and over
People
50
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07291297
Phase 1Taking people
Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors
Where
Fairfax, Los Angeles, New Haven, New York, Sarasota, St Louis
Age
18 years and over
People
180 worldwide
Run by
Zai Lab (Shanghai) Co., Ltd.
See details and how to joinNCT07374848
No phaseNot yet taking people in United States
Web-based Lifestyle Program, mHealth and EMA Intervention, to Improve Weight Loss in Rural Stage I-III Postmenopausal Breast and Endometrial Cancer Survivors, HERO-C Trial
Where
Columbus
Age
40 years to 69 years
People
90
Run by
Ohio State University Comprehensive Cancer Center
See details and how to joinNCT07723235