Sarcoma trials in United States

In United States 300 Also abroad 605

300 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial
Where
Seattle
Age
1 year to 75 years
People
30
Run by
Fred Hutchinson Cancer Center
See details and how to joinNCT07227571
No phaseEnrolling by invitation
Neurofibromatosis Type 1 Tumor Early Detection Study
Where
Boston
Age
18 years and over
People
1,000
Run by
David Miller
See details and how to joinNCT06515860
Phase 2Not yet taking people in United States
Phase 2 Study of Daraxonrasib in Recurrent KRAS-Mutant Biliary Tract Cancer
Where
Baltimore
Age
18 years and over
People
55
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
See details and how to joinNCT07793253
Early phase 1Taking people
N-803 in Patients With Progressive Synovial Sarcoma and Myxoid/Round Cell Liposarcoma Previously Treated With Adoptive Cellular Therapy
Where
Chicago
Age
18 years to 80 years
People
8
Run by
Seth Pollack
See details and how to joinNCT07261657
Phase 1Taking people
Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling
Where
Miami
Age
1 day to 21 years
People
65
Run by
Florida International University
See details and how to joinNCT05857969
No phaseNot yet taking people in United States
Tumor-Lymph Node Mapping
Where
Rochester
Age
1 month to 17 years
People
10
Run by
University of Rochester
See details and how to joinNCT07054944
No phaseTaking people
Bridging Adolescent and Young Adult Sarcoma Survivors With Personalized Oncology Exercise Service (AYA-ONE): A Pilot Intervention
Where
Boston
Age
15 years to 39 years
People
40
Run by
Dana-Farber Cancer Institute
See details and how to joinNCT07662239
Phase 1/2Taking people
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Where
Ann Arbor, Atlanta, Aurora, Birmingham, Boston, Chicago, Cincinnati, Houston, Indianapolis, Los Angeles, Memphis, Minneapolis, New York, Orange, Palo Alto, Philadelphia, Pittsburgh, San Francisco, Seattle, St Louis, Washington D.C.
Age
12 months to 30 years
People
147
Run by
Children's Oncology Group
See details and how to joinNCT04851119
Phase 3Taking people
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Where
Akron, Albany, Albuquerque, Allentown, Amarillo, Anaheim, Anchorage, Ann Arbor, Arroyo Grande, Asheville, Atlanta, Aurora, Austin, Baltimore, Bangor, Battle Creek, Bellevue, Bellflower, Bethesda, Birmingham, Boise, Boston, Brooklyn, Burlington, Carson City, Chapel Hill, Charleston, Charlottesville, Chicago, Cincinnati, Cleveland, Columbia, Columbus, Corpus Christi, Dallas, Danville, Dayton, Denver, Des Moines, Detroit, Downey, Durham, East Lansing, El Paso, Falls Church, Fargo, Fontana, Fort Myers, Fort Worth, Gainesville, Grand Rapids, Greenville, Hackensack, Hartford, Henderson, Hershey, Honolulu, Houston, Indianapolis, Iowa City, Jackson, Jacksonville, Kalamazoo, Kansas City, Kingman, Knoxville, Las Vegas, Lebanon, Lexington, Little Rock, Loma Linda, Long Beach, Los Angeles, Louisville, Madera, Madison, Marshfield, Maywood, Memphis, Mesa, Miami, Milwaukee, Minneapolis, Morgantown, Morristown, Muskegon, Nashville, New Brunswick, New Haven, New Hyde Park, New Orleans, New York, Niles, Norfolk, Norton Shores, Oakland, Oklahoma City, Omaha, Orange, Orlando, Pahrump, Palo Alto, Paterson, Peoria, Philadelphia, Phoenix, Pittsburgh, Portland, Providence, Reed City, Reno, Renton, Richmond, Roanoke, Rochester, Royal Oak, Sacramento, Saint Joseph, Salt Lake City, San Antonio, San Diego, San Francisco, Scarborough, Seattle, Sioux Falls, Spokane, St Louis, Stony Brook, St. Petersburg, Syracuse, Tacoma, Tampa, The Bronx, Toledo, Traverse City, Tucson, Valhalla, Washington D.C., Wilmington, Winfield, Winston-Salem, Wyoming, Yakima
Age
Up to 50 years
People
62 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT05235165
Phase 3Taking people
Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma
Where
Akron, Albany, Albuquerque, Allentown, Ann Arbor, Atlanta, Aurora, Austin, Baltimore, Birmingham, Boise, Boston, Buffalo, Chapel Hill, Charleston, Charlotte, Charlottesville, Chicago, Cincinnati, Cleveland, Columbia, Columbus, Corpus Christi, Dallas, Danville, Dayton, Denver, Des Moines, Detroit, Downey, Durham, El Paso, Falls Church, Fargo, Fort Lauderdale, Fort Myers, Fort Worth, Gainesville, Grand Rapids, Greenville, Hackensack, Hartford, Hershey, Hollywood, Honolulu, Houston, Indianapolis, Iowa City, Jackson, Jacksonville, Kalamazoo, Kansas City, Knoxville, Las Vegas, Lebanon, Lexington, Little Rock, Loma Linda, Long Beach, Los Angeles, Louisville, Lubbock, Macon, Madera, Madison, Marshfield, Maywood, Memphis, Miami, Milwaukee, Minneapolis, Mobile, Morristown, Nashville, Neptune City, Newark, New Brunswick, New Haven, New Hyde Park, New Orleans, New York, Norfolk, Oakland, Oak Lawn, Oklahoma City, Omaha, Orange, Orlando, Palo Alto, Park Ridge, Pensacola, Peoria, Philadelphia, Phoenix, Pittsburgh, Portland, Providence, Reno, Richmond, Roanoke, Rochester, Royal Oak, Sacramento, Salt Lake City, San Antonio, San Diego, San Francisco, Savannah, Scarborough, Seattle, Sioux Falls, Spokane, Springfield, St Louis, St. Petersburg, Syracuse, Tacoma, Tampa, Temple, The Bronx, Toledo, Valhalla, Washington D.C., West Palm Beach, Wichita, Wilmington, Winfield, Winston-Salem, Worcester
Age
Up to 21 years
People
205 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT05304585
Phase 2Taking people
Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)
Where
Bethesda
Age
18 years to 120 years
People
55
Run by
National Cancer Institute (NCI)
See details and how to joinNCT07308886
Phase 3Taking people
A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)
Where
Akron, Albany, Allentown, Asheville, Atlanta, Aurora, Austin, Baltimore, Bath, Battle Creek, Birmingham, Boston, Charlottesville, Chicago, Corpus Christi, Dallas, Denver, Des Moines, Duarte, Falls Church, Fort Myers, Grand Rapids, Hartford, Hollywood, Indianapolis, Jackson, Jacksonville, Kalamazoo, Kansas City, Knoxville, Lexington, Little Rock, Loma Linda, Los Angeles, Louisville, Madera, Madison, Milwaukee, Mobile, Muskegon, Nashville, Niles, Norfolk, Norton Shores, Oakland, Omaha, Orange, Orlando, Pensacola, Philadelphia, Pittsburgh, Portland, Providence, Reed City, Reno, Rochester, Saint Joseph, Salt Lake City, San Antonio, Sanford, Scarborough, Seattle, St Louis, St. Petersburg, Tacoma, The Bronx, Toledo, Traverse City, West Palm Beach, Wichita, Wilmington, Worcester, Wyoming
Age
Up to 50 years
People
342 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT07466316
Phase 2Taking people
Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas
Where
Birmingham
Age
18 years to 99 years
People
41
Run by
University of Alabama at Birmingham
See details and how to joinNCT05253131
Phase 2Not yet taking people in United States
RAPID: Phase 2 Platform Trial Of Promising Drugs For AYA Patients With R/R Ewing Sarcoma & DSRCT
Where
Houston
Age
10 years and over
People
120
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT07781891
No phaseTaking people
Molecular Testing for the MD Anderson Cancer Center Personalized Cancer Therapy Program
Where
Houston
People
12,000
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT01772771
Phase 1/2Taking people
Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
Where
Buffalo
Age
18 years and over
People
99
Run by
Roswell Park Cancer Institute
See details and how to joinNCT03965234
No phaseTaking people
Enhanced Recovery After Surgery in Extremity Sarcoma
Where
Nashville
Age
18 years and over
People
120
Run by
Joshua Lawrenz
See details and how to joinNCT04461171
No phaseTaking people
Integration of Adaptive Proton Therapy in Pediatric Solid Tumors and Hodgkin's Lymphoma
Where
Memphis
People
100
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT07514819
Phase 1/2Taking people
Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors
Where
Jacksonville
Age
16 years and over
People
138
Run by
Mayo Clinic
See details and how to joinNCT05269381
Phase 1Taking people
Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)
Where
Dallas
Age
18 years and over
People
105
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07139990
Phase 1Taking people
Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)
Where
Washington D.C.
Age
1 year to 23 years
People
18
Run by
Children's National Research Institute
See details and how to joinNCT07172958
Phase 1Taking people
A Study of MQ710 With and Without Pembrolizumab in People With Solid Tumor Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Uniondale
Age
18 years and over
People
56
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT05859074
No phaseTaking people
Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma
Where
Houston
Age
10 years and over
People
20
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04199026
Phase 1/2Taking people
SPEARHEAD-3 Pediatric Study
Where
Bethesda, Boston, Cincinnati, Durham, Madison, New York, Palo Alto, Philadelphia, Seattle, St Louis
Age
2 years to 21 years
People
20
Run by
USWM CT, LLC
See details and how to joinNCT05642455
Phase 3Taking people
A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)
Where
Columbus, Durham, Farmington Hills, Los Angeles, New Haven, Omaha, Philadelphia, Santa Monica
Age
18 years and over
People
333 worldwide
Run by
Intensity Therapeutics, Inc.
See details and how to joinNCT06263231 · EU 2024-512423-36-00