Schizophrenia trials in United States

In United States 179 Also abroad 473

179 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Alternative Stimulation Mode and Location for Auditory Hallucination Neuromodulation Treatment
Where
Houston
Age
18 years to 50 years
People
140
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT02916810
Phase 4Taking people
Biomarkers to Enhance Early Schizophrenia Treatment
Where
Belmont, Birmingham, Glen Oaks, La Jolla
Age
18 years to 35 years
People
180 worldwide
Run by
Northwell Health
See details and how to joinNCT06969755
No phaseTaking people
BRAVE Program to Improve Safety and Reduce Violence Risk in Early Psychosis
Where
Washington D.C.
Age
16 years to 30 years
People
30
Run by
Howard University
See details and how to joinNCT07417904
Phase 2Taking people
Study to Assess the Safety, Tolerability, and Treatment Response of GXV813 in Hospitalized Adults With Schizophrenia
Where
Bentonville, Chicago, Decatur, Miami, Pico Rivera, St Louis
Age
18 years to 65 years
People
142 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07467993
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Roluperidone in Adult Subjects With Negative Symptoms and Stable Positive Symptoms of Schizophrenia and to Evaluate the Relapse Rate of Roluperidone and Antipsychotic Medications
Where
Atlanta, Bellflower, Culver City, Decatur, Gaithersburg, Garden Grove, Hallandale, Hollywood, Marlton, New York, Richardson, Riverside, Tampa
Age
18 years to 55 years
People
380
Run by
Minerva Neurosciences
See details and how to joinNCT07565428
No phaseTaking people
Determining the Role of Social Reward Learning in Social Anhedonia
Where
Birmingham, Los Angeles
Age
18 years to 35 years
People
152
Run by
University of Alabama at Birmingham
See details and how to joinNCT05617898
Phase 3Taking people
Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia
Where
Bentonville, Boynton Beach, Chicago, Culver City, Garden Grove, Lemon Grove, Little Rock, Miami Lakes, North Canton, Riverside, Snellville, St Louis
Age
18 years to 65 years
People
456
Run by
LB Pharmaceuticals Inc.
See details and how to joinNCT07363577
Phase 3Taking people
Cognitive Strategies in Early Psychosis 2
Where
Minneapolis
Age
18 years to 35 years
People
24
Run by
University of Minnesota
See details and how to joinNCT07263022
No phaseTaking people
Transition Care for FEP
Where
Chicago, Harvey
Age
18 years to 40 years
People
75
Run by
University of Chicago
See details and how to joinNCT07713849
Phase 1/2Taking people
Tolerability of MDMA in Schizophrenia
Where
Los Angeles
Age
18 years to 60 years
People
20
Run by
Anya Bershad, MD, PhD
See details and how to joinNCT05770375
No phaseTaking people
Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness
Where
Charlestown
Age
18 years to 55 years
People
120
Run by
Massachusetts General Hospital
See details and how to joinNCT04940663
Phase 2Taking people
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Where
Boston, Sunnyvale
Age
18 years to 65 years
People
180
Run by
Brigham and Women's Hospital
See details and how to joinNCT06376734
Phase 1/2Taking people
A PET/MRI Study of Cobenfy on Dopamine Transmission in Schizophrenia
Where
New York
Age
18 years to 50 years
People
12
Run by
New York State Psychiatric Institute
See details and how to joinNCT07423546
No phaseTaking people
MicroRNAs as Biomarkers in First Episode Schizophrenia
Where
Glen Oaks
Age
15 years to 40 years
People
160
Run by
Northwell Health
See details and how to joinNCT07703670
Phase 4Taking people
Anticholinergic Deprescription in Schizophrenia
Where
Pittsburgh
Age
40 years to 70 years
People
105
Run by
Deepak K. Sarpal, M.D.
See details and how to joinNCT06562608
No phaseTaking people
Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)
Where
Dallas
People
100
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT03906435
Phase 1/2Taking people
Acetazolamide for Treatment Resistant Schizophrenia
Where
Pittsburgh
Age
18 years to 55 years
People
60 worldwide
Run by
Vishwajit Nimgaonkar, MD PhD
See details and how to joinNCT04887792
No phaseTaking people
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 1)
Where
Houston
Age
18 years to 60 years
People
120
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT06345963
No phaseTaking people
Enhancing Brain Connectivity in Schizophrenia Through Neuromodulation (Study 2)
Where
Houston
Age
18 years to 60 years
People
120
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT06961916
No phaseTaking people
SPARK Healthy Sleep
Where
Indianapolis
Age
18 years to 65 years
People
115
Run by
Indiana University
See details and how to joinNCT07119268
No phaseTaking people
Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness
Where
Pittsburgh
Age
18 years to 70 years
People
112
Run by
VA Office of Research and Development
See details and how to joinNCT05157620
Phase 3Taking people
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Where
Chino, Cleveland, Gilbert, Independence, Naples
Age
55 years to 90 years
People
325 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06947941
Phase 1/2Not yet taking people in United States
A Cognitive Mobile Intervention for Motivation in Psychotic Disorders
Where
Birmingham
Age
18 years to 60 years
People
45
Run by
University of Alabama at Birmingham
See details and how to joinNCT07674914
No phaseNot yet taking people in United States
Optimizing CBSST With Executive Function Training for Schizophrenia (R33)
Where
Dallas, San Diego
Age
60 years and over
People
106
Run by
University of California, San Diego
See details and how to joinNCT07658391
No phaseTaking people
Digital Strategies to Advance Help-Seeking - Aim 3
Where
New York
Age
12 years to 29 years
People
25,000
Run by
Columbia University
See details and how to joinNCT06774417