Type 2 diabetes trials in United States
393 trials · From ClinicalTrials.gov, checked 10 Nov 2026. Ask the study team whether a trial fits you.
Phase 3RecruitingTrial-stage medicine
A Study to Learn About Berobenatide Given Once Weekly in Adults With Knee Osteoarthritis and Overweight or Obesity With or Without Type 2 Diabetes (VESPER-OA 2)
- Where
- Birmingham, Miami, Shelby, Tucson
- Age
- 18 years and over
- People
- 756
- Run by
- Pfizer
See details and how to joinNCT07915609EU 2026-527180-15-00Registry updated 2026-11-04
No phaseRecruitingResearch participation
CGM-Enhanced DPP to Prevent Type 2 Diabetes in Adults With Prediabetes
- Where
- Buffalo
- Age
- 18 years and over
- People
- 100
- Run by
- State University of New York at Buffalo
See details and how to joinNCT07140848Registry updated 2026-11-03
Phase 2RecruitingTrial-stage medicine
A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event
- Where
- Altamonte Springs, Buffalo, Cincinnati, Cutler Bay, Cypress, Dearborn, Foxborough, Glendora, Houston, Huntsville, Indianapolis, Kingwood, Las Vegas, Lombard, Maitland, Manassas, McKinney, North Charleston, Ogden, Olive Branch, Orlando, Reston, The Bronx, Tucson, West Chester, Woodstock, Yardley
- Age
- 18 years and over
- People
- 120 worldwide
- Run by
- Eli Lilly and Company
See details and how to joinNCT07783802Registry updated 2026-11-03
Phase 3Not yet recruitingTrial-stage medicine
A Study of EloraTZP in Adult Participants With Obesity Without Type 2 Diabetes
- Where
- Albuquerque, Arlington, Atlantis, Baltimore, Bellaire, Boston, Chapel Hill, Chicago, Covina, Dallas, Dalton, Dunwoody, Euless, Eunice, Greensboro, Honolulu, Houston, Indianapolis, Kingwood, Las Vegas, Long Island City, Los Angeles, Maitland, Memphis, Mesa, Metairie, Miami, New Haven, Newport News, New York, Norfolk, Philadelphia, Plymouth Meeting, Raleigh, Ridgeland, Rolling Hills Estates, San Antonio, San Diego, Santa Ana, Scottsdale, Shavano Park, Stockbridge, Tamarac, Tampa, Tucson, Tyler, Union City, West Valley City
- Age
- 18 years and over
- People
- 2,115 worldwide
- Run by
- Eli Lilly and Company
See details and how to joinNCT07881432EU 2026-526047-34-00Registry updated 2026-11-03
Phase 2Not yet recruitingTrial-stage medicine
A Study to Investigate the Effect of LY4086940 Versus Placebo in Participants With Obesity or Overweight and Without Type 2 Diabetes
- Where
- Amherst, Ammon, Austin, Chandler, Chicago, Cincinnati, City of Saint Peters, Dallas, Danville, Greenbrae, Greenville, Huntington Park, Las Vegas, Miami, Miami Lakes, Monroe, Morehead City, Nashville, Needham, New Bedford, New Bern, New Port Richey, Orlando, Rochester, Rolling Hills Estates, San Antonio, Scottsdale, Southfield, Springfield, Stamford, The Villages, Topeka, Troy, Tucson, Walnut Creek, Wenatchee, Weslaco, West Des Moines
- Age
- 18 years to 75 years
- People
- 460 worldwide
- Run by
- Eli Lilly and Company
See details and how to joinNCT07890376Registry updated 2026-11-03
Phase 3Not yet recruitingTrial-stage medicine
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
- Where
- Altamonte Springs, Amarillo, Apache Junction, Arlington, Arlington Heights, Augusta, Baltimore, Birmingham, Brandon, Cincinnati, Corvallis, Covina, Cutler Bay, Dallas, East Providence, El Paso, Escondido, Exton, Fleming Island, Fort Worth, Franklin, Gilbert, Greenfield, Honolulu, Houston, Humble, Huntsville, Jacksonville, Lancaster, Las Vegas, Leesburg, Long Beach, Longview, McAllen, McKinney, Media, Miami, Morehead City, Nashua, New Bedford, Norfolk, Northridge, Ogden, Oxnard, Pasadena, Pembroke Pines, Phoenix, Port Charlotte, Redmond, Richmond, Ridgeland, Rochester, Saint Joseph, San Antonio, San Diego, Santa Clarita, Southfield, Springfield, Surprise, Tinley Park, Waterbury, Westlake Village, Wilmington, Wylie
- Age
- 45 years to 64 years
- People
- 3,000 worldwide
- Run by
- Eli Lilly and Company
See details and how to joinNCT07900633EU 2026-525919-14-00Registry updated 2026-11-03
No phaseNot yet recruitingResearch participation
Clinical Research Trial to Study Insulin Sensitivity Using Automated Glucose Clamp Technology
- Where
- Webster
- Age
- 18 years to 65 years
- People
- 50
- Run by
- Profil Institut für Stoffwechselforschung GmbH
See details and how to joinNCT07913698Registry updated 2026-11-03
No phaseRecruitingResearch participation
Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes
- Where
- Nashville
- Age
- 6 years to 59 years
- People
- 30
- Run by
- Vanderbilt University
See details and how to joinNCT06482944Registry updated 2026-11-02
No phaseNot yet recruitingResearch participation
SWitching to Appropriate Prescription in Cardiovascular-Kidney-Metabolic Syndrome
- Where
- Pleasanton
- Age
- 18 years and over
- People
- 1,200
- Run by
- Kaiser Permanente
See details and how to joinNCT07910968Registry updated 2026-11-02
No phaseNot yet recruitingResearch participation
Peer Support and Remote Patient Monitoring for Black Adults With Type 2 Diabetes
- Where
- Birmingham
- Age
- 19 years and over
- People
- 200
- Run by
- University of Alabama at Birmingham
See details and how to joinNCT07181304Registry updated 2026-10-30
No phaseNot yet recruitingResearch participation
Role of Endothelial Dysfunction on Exercise Pressor Reflex in Type 2 Diabetes
- Where
- Milwaukee
- Age
- 18 years to 80 years
- People
- 40
- Run by
- Medical College of Wisconsin
See details and how to joinNCT07228208Registry updated 2026-10-30
No phaseRecruitingResearch participation
Culturally Tailored Program for Food-Insecure Adults: SPICE-D
- Where
- Winston-Salem
- Age
- 18 years and over
- People
- 25
- Run by
- Wake Forest University Health Sciences
See details and how to joinNCT07361341Registry updated 2026-10-30
Phase 3RecruitingTrial-stage medicine
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
- Where
- Albuquerque, Annapolis, Atlanta, Bakersfield, Beachwood, Boston, Brooklyn, Chicago, Dallas, Elkhorn, Evansville, Huntsville, Kingsport, Kingwood, Lake City, Lakeland, Layton, Little Rock, Los Angeles, Lutherville-Timonium, Maumee, McKinney, Mobile, Nashville, Newport News, Norman, Ontario, Oxon Hill, Paris, Philadelphia, Raleigh, Redmond, Ridgeland, Rosedale, San Antonio, Sheffield, Sioux City, Skokie, South Jordan, Toms River, Troy, Vienna, Webster, Zachary
- Age
- 18 years and over
- People
- 2,000 worldwide
- Run by
- AstraZeneca
See details and how to joinNCT07662109EU 2025-523941-81-00Registry updated 2026-10-30
Phase 3RecruitingTrial-stage medicine
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
- Where
- Ames, Arlington, Bridgeport, Butte, Champaign, Chicago, Clearwater, Columbus, Cortland, Dothan, El Dorado, Escondido, Fargo, Houston, Huntsville, Jacksonville, Jefferson City, Jersey City, Kansas City, Kingsport, Las Vegas, Maumee, Memphis, Mesa, Owensboro, Philadelphia, Portland, Renton, Rochester, Rocky Mount, Salt Lake City, San Antonio, Seattle, Smithfield, Statesville, Stockbridge, Sugar Land, Troy, Tulsa, Waco, Wilmington
- Age
- 18 years and over
- People
- 2,500 worldwide
- Run by
- AstraZeneca
See details and how to joinNCT07784725EU 2025-523379-41-00Registry updated 2026-10-30
No phaseNot yet recruitingResearch participation
Physiologic Insulin Resensitization (PIR) Treatment in Patients With a Diagnosis of Type 2 Diabetes Mellitus (T2DM)
- Where
- Birmingham
- Age
- 18 years and over
- People
- 60
- Run by
- University of Alabama at Birmingham
See details and how to joinNCT07906470Registry updated 2026-10-30
No phaseEnrolling by invitationResearch participation
Personalizing A1c Using Hematologic Indices and CGM for Accurate Diabetes Diagnosis
- Where
- Boston
- Age
- 65 years and over
- People
- 45
- Run by
- Brigham and Women's Hospital
See details and how to joinNCT07111416Registry updated 2026-10-29
No phaseRecruitingResearch participation
Neuromodulation for Metabolic Dysfunction
- Where
- Lexington
- Age
- 18 years and over
- People
- 120
- Run by
- Rahul Sachdeva
See details and how to joinNCT07597161Registry updated 2026-10-29
Phase 3RecruitingTrial-stage medicine
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
- Where
- Albuquerque, Austin, Birmingham, Blackfoot, Bluffton, Brooklyn, Brownsville, Buckley, Canoga Park, Canton, Chattanooga, Clearwater, Columbus, Concord, Conroe, Dallas, Dearborn, Escondido, Fayetteville, Fort Myers, Georgetown, Gilbert, Greensboro, Hollywood, Honolulu, Houston, Idaho Falls, Kalispell, Lakeland, Largo, Las Vegas, Lawrenceville, Lexington, Lincoln, Little Rock, Long Beach, Maumee, Memphis, Meridian, Mesquite, Miami, Minneapolis, Missoula, Morehead City, Newport News, Northridge, Oklahoma City, Olive Branch, Paradise Valley, Phoenix, Pittsburgh, Redmond, Riverview, Rockville, Salt Lake City, San Antonio, Shavano Park, Spartanburg, Spring Valley, Troy, Union City, Uniontown, University Park, Walnut Creek, West Hills, Weston, Winter Park
- Age
- 18 years and over
- People
- 600 worldwide
- Run by
- Boehringer Ingelheim
See details and how to joinNCT07754461Registry updated 2026-10-29
No phaseNot yet recruitingResearch participation
Care COMPASS Study
- Where
- Portland
- Age
- 18 years and over
- People
- 200
- Run by
- Fitbit LLC
See details and how to joinNCT07904793Registry updated 2026-10-29
No phaseRecruitingResearch participation
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
- Where
- Sioux Falls
- People
- 20,000
- Run by
- Sanford Health
See details and how to joinNCT01793168Registry updated 2026-10-28
Phase 2Not yet recruitingTrial-stage medicine
The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction
- Where
- Rochester
- Age
- 25 years to 65 years
- People
- 20
- Run by
- Adrian Vella
See details and how to joinNCT05499702Registry updated 2026-10-28
Phase 3RecruitingTrial-stage medicine
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
- Where
- Albany, Albuquerque, Anniston, Aurora, Austin, Avon, Baltimore, Beaver, Beverly Hills, Billings, Binghamton, Boca Raton, Bossier City, Bowling Green, Bridgeport, Bridgewater, Brownsville, Buffalo, Camp Hill, Canoga Park, Cary, Chandler, Chapel Hill, Chicago, Cincinnati, Clearwater, Columbus, Concord, Covington, Cutler Bay, Dakota Dunes, Dallas, Dearborn, DeLand, Doral, El Dorado, Elkhart, El Paso, Fairhope, Falls Church, Fargo, Fayette, Fleming Island, Flint, Forney, Fort Mill, Fort Myers, Fort Worth, Franklin, Fremont, Gaffney, Golden, Greenfield, Greenville, Guntersville, Hallandale, Hamden, Honolulu, Houston, Huntington Park, Idaho Falls, Jacksonville, Jefferson City, Johns Creek, Kansas City, Kenosha, Kissimmee, Knoxville, Lake City, Lakeland, La Mesa, Lancaster, Las Vegas, Lenoir, Lewisville, Lexington, Linden, Lombard, Long Beach, Macon, Malden, Manassas, Marietta, Mesquite, Methuen, Miami, Miami Lakes, Monroe, Mooresville, Morehead City, Morgantown, Muncie, Naples, New Port Richey, New York, Norfolk, North Las Vegas, Oak Lawn, Oklahoma City, Olney, Omaha, Orange, Orlando, Ormond Beach, Owensboro, Oxon Hill, Palm Beach Gardens, Palmetto Bay, Pembroke Pines, Philadelphia, Phoenix, Pittsburgh, Pomona, Port Charlotte, Richmond, Riverhead, Riverview, Rochester, Saint Augustine, Salisbury, Salt Lake City, San Antonio, San Bernardino, San Diego, San Marcos, Santa Rosa, Saratoga Springs, Savannah, Scottdale, Shavano Park, Sherman, Shreveport, Slidell, Smithfield, Somerset, Stamford, Stephenville, St Louis, St. Petersburg, Sun City West, Tacoma, Tempe, Thomasville, Tomball, Topeka, Torrance, Troy, Tucker, Tucson, Union, Uniontown, University Park, Vista, Waco, Wausau, Wauwatosa, Wellington, Weslaco, West Chester, Westfield, West Jordan, Westlake, West Monroe, West Seneca, Wichita, Wilmington, Winchester, Winston-Salem, Yardley, Yuma, Zachary
- Age
- 18 years and over
- People
- 11,800 worldwide
- Run by
- Boehringer Ingelheim
See details and how to joinNCT07064473EU 2025-521188-11-00Registry updated 2026-10-28
Phase 3RecruitingTrial-stage medicine
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
- Where
- Ames, Bakersfield, Beltsville, Chicago, DeSoto, Doral, Eatontown, El Paso, Fairhope, Farmington Hills, Fayette, Fleming Island, Fort Lauderdale, Franklin, Gardena, Greensboro, Houston, Huntsville, Jackson, Kansas City, Knoxville, Lanham, Lenexa, Lincoln, Little Rock, Manassas, Melrose Park, Mesa, Midland, Mobile, Monroe, Newton, Norfolk, North Dartmouth, Oak Brook, Ocoee, Omaha, Oxon Hill, Pasadena, Phoenix, Rockville, San Antonio, Scottdale, Somerset, St Louis, Stow, Torrance, Tucson, Walnut Creek, Warren Township, Woodstock
- Age
- 18 years and over
- People
- 1,500 worldwide
- Run by
- AstraZeneca
See details and how to joinNCT07784270Registry updated 2026-10-28
Phase 2RecruitingTrial-stage medicine
Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease
- Where
- Ann Arbor, Arlington, Bethlehem, Binghamton, Chattanooga, Chicago, City of Saint Peters, Dallas, DeSoto, Doral, El Paso, Greenville, Hialeah, Hollywood, Houston, Huntington Beach, Huntsville, Kansas City, Katy, Las Vegas, Little Rock, Margate, McKinney, Miami, Miami Springs, Miramar, Monroe, New Bern, New Haven, Northridge, Omaha, Orlando, Oxnard, Pembroke Pines, Pontiac, Port Orange, Port Saint Lucie, Salinas, San Antonio, San Dimas, Santa Clarita, Savannah, Spokane, Tamarac, Tarzana, The Bronx, Valencia, Victorville, West Chester, West Palm Beach, Winston-Salem
- Age
- 18 years to 80 years
- People
- 195
- Run by
- Regeneron Pharmaceuticals
See details and how to joinNCT07271186EU 2026-527519-41-00Registry updated 2026-10-27
No phaseEnrolling by invitationResearch participation
MTM2MTG Pilot Ancillary Study
- Where
- New York
- Age
- 20 years and over
- People
- 80
- Run by
- Columbia University
See details and how to joinNCT07620808Registry updated 2026-10-26
All Type 2 diabetes trials and the map
This page is not medical advice. Talk to your doctor before contacting a trial.