Clinical trials

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164 trials

NCT07175051
Recruiting
Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin
Phase 2 · United States · 1 site
Registry update: 19 May 2026
NCT07442851
Recruiting
SickleFit Exercise and Nutrition Study
Not applicable · United States · 1 site
Registry update: 7 May 2026
NCT07610239
Recruiting
Evaluation of an Information Management and Communication System for Population-wide Point-of-Care Infant Sickle Cell Disease Screening
Not applicable · Uganda · 1 site
Registry update: 27 May 2026
2024-513750-30-00
Recruiting
Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children with Sickle Cell Disease: a single-group, non-randomised, open-label study (KID-BID)
Phase 2 · France · 6 sites
Registry update: 24 Jul 2026
NCT06016634
Recruiting
Alendronate for Osteonecrosis in Adults With Sickle Cell Disease
Phase 2 · United States · 1 site
Registry update: 16 Jul 2026
NCT07246265
Recruiting
Morphine Clearance and Glomerular Filtration in Sickle Cell Patients in Crisis in Intensive Care
Not applicable · France · 6 sites
Registry update: 10 Mar 2026
NCT07432867
Recruiting
Efficacy Safety Study of Gene Therapy for Sickle Cell DiseaseSCD Using Autologous CD34+ Cells Transduced ex Vivo, Carrying a Corrected Globin Gene and a Silencing RNA.
Phase 1/2 · France · 1 site
Registry update: 4 Mar 2026
NCT06260891
Recruiting
Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial
Phase 2 · United States · 6 sites
Registry update: 13 Mar 2026
NCT07222475
Recruiting
Writing Relaxing Beats in Adolescents Who Have Sickle Cell Disease
Not applicable · United States · 1 site
Registry update: 23 Feb 2026
NCT06761560
Recruiting
Optimizing Hydroxyurea Dosage With Pharmakokinetic in Patients Suffering of Moderate to Severe Sickle Cell Anemia
Phase 2/3 · Canada · 1 site
Registry update: 21 Aug 2026
NCT07224360
Recruiting
Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)
Phase 2 · Belgium, France, United Kingdom, Italy, Netherlands, United States · 40 sites
Registry update: 3 Nov 2026
NCT07488091
Recruiting
Multi Disciplinary Sickle Cell Disease Obstetrics Care Program in Ghana
Not applicable · Ghana · 1 site
Registry update: 23 Mar 2026
NCT07247188
Recruiting
Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease
Phase 3 · Dominican Republic, United States · 7 sites
Registry update: 15 Apr 2026
NCT07316478
Recruiting
Stress Management and Mindfulness Intervention for Patients With Sickle Cell Disease
Not applicable · United States · 1 site
Registry update: 27 Feb 2026
NCT06919224
Recruiting
Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease
Not applicable · United States · 4 sites
Registry update: 23 Mar 2026
NCT07187973
Recruiting
A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)
Phase 1 · United States · 11 sites
Registry update: 5 Oct 2026
NCT07373639
Recruiting
A Long-term Follow-up Study in Patients Who Received BEAM-101
Not applicable · United States · 17 sites
Registry update: 28 Jan 2026
NCT06647979
Recruiting
Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-Hemoglobinopathies
Phase 1 · United States · 1 site
Registry update: 3 Feb 2026
NCT07226219
Recruiting
Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease
Phase 1 · United States · 1 site
Registry update: 9 Sept 2026
NCT06555939
Recruiting
Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease
Not applicable · United States · 1 site
Registry update: 5 May 2026

Ordered by registry start date. Freshness and sponsorship never change the order.