Amyloidosis: trials for referral
202 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
Type a city to sort by distance. The distance is worked out in your browser; the city is not sent anywhere.
202 trials shown
No phase7 sites
RecruitingSwitzerland
NCT04776824
Swiss Cardiac Amyloidosis REgistry (Swiss-CARE)
Insel Gruppe AG, University Hospital Bern
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingIsrael
NCT06971380
Study of HBI0101 (NXC-201) CAR-T Therapy in Multiple Myeloma and Light-Chain Amyloidosis
Polina Stepensky
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govNo phase8 sites
RecruitingGermany, Spain, France, United Kingdom, United States
NCT06978660
Multicenter Study for the Validation of an AI-based ECG Platform for Early Cardiac Amyloidosis Diagnosis
Idoven 1903 S.L.
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 3143 sites
RecruitingArgentina, Austria, Australia, Belgium, Brazil, Canada
NCT06128629
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
Intellia Therapeutics
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 129 sites
RecruitingBelgium, Spain, France, United Kingdom, Japan, Netherlands
NCT05652335
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis
Janssen Research & Development, LLC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 226 sites
RecruitingAustralia, Spain, United Kingdom, Greece, Italy, United States
NCT07224672
A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Cyclophosphamide, Bortezomib, and Dexamethasone in Adult Participants With Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis
GlaxoSmithKline
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingUnited States
NCT05974644
Southeastern ATTR Amyloidosis Consortium: SEATTRAC Family Registry
Virginia Commonwealth University
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingUnited States
NCT07591038
PET/CT Imaging in Carriers of TTR Mutations
University of Texas Southwestern Medical Center
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingFrance
NCT06845644
Longitudinal Quantitative Neuromuscular MRI in Neuropathic Patients
Assistance Publique Hopitaux De Marseille
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT01137643
Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer
UNC Lineberger Comprehensive Cancer Center
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 30 sites
Not yet recruiting
NCT07901725
Linvoseltamab Versus Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone (Dara-Vcd) in Adult Participants With Newly Diagnosed Systemic Light Chain Amyloidosis
Regeneron Pharmaceuticals
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingSpain
NCT06527521
Prevalence of Amyloidosis in Trauma Patients
Consorci Sanitari de l'Alt Penedès i Garraf
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govNo phase30 sites
RecruitingUnited States
NCT07112924
CCM OPEN HF Registry
Impulse Dynamics
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govEarly Phase 11 site
Not yet recruitingUnited States
NCT07615270
A Pilot Study of Anselamimab in Patients With AL Amyloidoma and Measurable Tissue Involvement
Stanford University
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govNo phase3 sites
Not yet recruitingAustria, Germany, Italy
NCT07557147
Single-arm, Multi-center Study Evaluating the Acceptance and Feasibility of a Digital Remote Monitoring Tool Configured for Patients With ATTR-CM: ACO-Monitor
Bayer
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.govNo phase13 sites
RecruitingUnited States
NCT06365060
Screening for AL Amyloidosis in Smoldering Multiple Myeloma
Tufts Medical Center
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.govPhase 21 site
Not yet recruitingBrazil
NCT07836699
Effect of Trimetazidine on Coronary Flow in Transthyretin Cardiac Amyloidosis
Fábio Fernandes
Registry updated 23 Oct 2026
Registry record: ClinicalTrials.govNo phase3 sites
Not yet recruitingUnited States
NCT07538518
PET Imaging Study Using Evuzamitide to Detect Cardiac Amyloidosis in Patients With Inconclusive Nuclear Scans and Elevated TAD1 Levels
Lorena Saelices
Registry updated 22 Oct 2026
Registry record: ClinicalTrials.govPhase 3298 sites
RecruitingArgentina, Australia, Belgium, Brazil, Canada, China
NCT07207811
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Novo Nordisk A/S
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.govPhase 373 sites
By invitation onlyArgentina, Austria, Belgium, Brazil, Czechia, Denmark
NCT06679946
A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.govPhase 3244 sites
RecruitingArgentina, Austria, Australia, Belgium, Brazil, Canada
NCT07052903
TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy
Alnylam Pharmaceuticals
Registry updated 20 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
Not yet recruitingIsrael
NCT07874334
Phase 1a/b Study of GPRC5D CART Therapy in Relapsed/Refractory Multiple Myeloma and Light-chain Amyloidosis
Hadassah Medical Organization
Registry updated 20 Oct 2026
Registry record: ClinicalTrials.govNo phase10 sites
RecruitingAustria, Germany, Italy
NCT06075823
Edge-to-edge Mitral Valve Repair in ATTR-CM
Medical University of Vienna
Registry updated 16 Oct 2026
Registry record: ClinicalTrials.govPhase 426 sites
RecruitingAustria, Belgium, Germany, Italy, Norway
NCT07298044
A Study to Learn More About the Change in the Blood Levels of Transthyretin When Participants With Transthyretin Amyloidosis With Cardiomyopathy Switch From Tafamidis to Acoramidis
Bayer
Registry updated 15 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07583823
Elevated Rate Pacing of Cardiac Amyloidosis
University of Minnesota
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.govNo phase40 sites
RecruitingBulgaria, Brazil, Germany, Denmark, Spain, France
NCT04561518
ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)
Alnylam Pharmaceuticals
Registry updated 13 Oct 2026
Registry record: ClinicalTrials.govNo phase27 sites
RecruitingGermany, Japan, United States
NCT07358078
DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting
Alnylam Pharmaceuticals
Registry updated 9 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingFrance
NCT07494942
Impact of a Cardiac Rehabilitation Program on Patients With Cardiac Amyloidosis
University Hospital, Montpellier
Registry updated 8 Oct 2026
Registry record: ClinicalTrials.govPhase 358 sites
RecruitingArgentina, Australia, Brazil, Canada, Switzerland, Cyprus
NCT07223203
TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy
Alnylam Pharmaceuticals
Registry updated 8 Oct 2026 · The registries disagree on the status
Registry record: ClinicalTrials.govNo phase7 sites
RecruitingGermany, Spain, France, Italy, Netherlands, Portugal
NCT05040373
Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program
Alnylam Pharmaceuticals
Registry updated 8 Oct 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- United States69 open trials
- China38 open trials
- Italy36 open trials
- Germany33 open trials
- France31 open trials
- Spain25 open trials
- United Kingdom20 open trials
- Netherlands17 open trials
- Sweden14 open trials
- Japan13 open trials
- Belgium13 open trials
- Denmark13 open trials
- Portugal13 open trials
- Canada11 open trials
- Brazil11 open trials
- Argentina11 open trials
- South Korea10 open trials
- Austria10 open trials
- Australia10 open trials
- Switzerland8 open trials
- Taiwan8 open trials
- Greece8 open trials
- Israel7 open trials
- Norway6 open trials
- Czechia5 open trials
- Ireland5 open trials
- Mexico4 open trials
- Poland3 open trials
- Malaysia3 open trials
- Singapore2 open trials
- New Zealand2 open trials
- Hungary2 open trials
- Bulgaria2 open trials
- Romania1 open trials
- Chile1 open trials
- Cyprus1 open trials
- Latvia1 open trials
- Lithuania1 open trials
- Finland1 open trials
- Croatia1 open trials
- Slovenia1 open trials
- Estonia1 open trials
- Martinique1 open trials
- Uruguay1 open trials
- Thailand1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Brescia, Italy
3 trials · 28 publications · ROR
Berlin Institute of Health at Charité - Universitätsmedizin Berlin
Berlin, Germany
0 trials · 21 publications · ROR
Centro de Investigación en Red en Enfermedades Cardiovasculares
Madrid, Spain
0 trials · 62 publications · ROR
Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, China
0 trials · 81 publications · ROR
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola
Bologna, Italy
0 trials · 27 publications · ROR
The Ohio State University Wexner Medical Center
Columbus, United States
1 trials · 20 publications · ROR
The University of Texas MD Anderson Cancer Center
Houston, United States
0 trials · 40 publications · ROR
The University of Texas Southwestern Medical Center
Dallas, United States
1 trials · 64 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
Closed for recruitment
A Phase 3 Study of NTLA-2001 in ATTRv-PN
NCT06672237 · Phase 3 · Argentina, Brazil, Mexico, Singapore, Thailand, Taiwan
Source: ClinicalTrials.govOpened for recruitment
NCT07223203 · Phase 3 · Argentina, Australia, Brazil, Canada, Switzerland, Cyprus
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
NCT06712030 · Phase 3 · Spain
Source: ClinicalTrials.govOpened for recruitment
NCT06158854 · Phase 1/2 · Australia, France, Greece, Italy, Japan, United States
Source: ClinicalTrials.govStatus changed: Recruiting → By invitation only
Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001
NCT05697861 · Phase 2/3 · France, United Kingdom, New Zealand, Sweden
Source: ClinicalTrials.govClosed for recruitment
NCT06158854 · Phase 1/2 · Australia, France, Greece, Italy, Japan, United States
Source: ClinicalTrials.govClosed for recruitment
NCT07223203 · Phase 3 · Argentina, Australia, Brazil, Canada, Switzerland, Cyprus
Source: ClinicalTrials.govPhase changed: No phase → Phase 2/3
Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001
NCT05697861 · Phase 2/3 · France, United Kingdom, New Zealand, Sweden
Source: ClinicalTrials.gov
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
Phase 1Ended 7 Oct 2026
No phaseEnded 30 Sept 2026
Completed200 participants
NCT07605741
Fast Cardiac Bone SPECT-CZT in Transthyretin Cardiac Amyloidosis
No phaseEnded 10 Sept 2026
Completed47 participants
NCT07343999
EFICAC-TTR Trial: Exercise and Nutritional Supplementation in Transthyretin Cardiac Amyloidosis
Phase 3Ended 12 Aug 2026
Completed1438 participants
NCT04136171
CARDIO-TTRansform: A Study to Evaluate the Efficacy and Safety of Eplontersen (Formerly Known as ION-682884, IONIS-TTR-LRx and AKCEA-TTR-LRx) in Participants With Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR CM)
- Baseline characteristics of patients with transthyretin amyloid cardiomyopathy in the CARDIO-TTRansform trial of eplontersen. · European journal of heart failure, 2026
- Rationale and Design of CARDIO-TTRansform, a Phase 3 Trial of Eplontersen in Transthyretin Amyloid Cardiomyopathy. · Circulation. Heart failure, 2026
- Eplontersen with and without background transthyretin stabilizers in transthyretin amyloid cardiomyopathy: secondary analysis of a phase 3, randomized controlled trial. · Nature medicine, 2026
No phaseEnded Jul 2026
Phase 1Ended 17 Jun 2026
Phase 4Ended 4 Jun 2026
Phase 1Ended 2 Jun 2026
No phaseEnded 31 May 2026
Phase 3Ended 5 May 2026
Completed244 participants
NCT05184088
Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis
No phaseEnded 21 Apr 2026
Completed110 participants
NCT04801329
Korean Post-marketing Surveillance Vyndamax® Capsules for the Treatment of Transthyretin Amyloid Cardiomyopathy
Early Phase 1Ended 13 Apr 2026
Completed10 participants
NCT05023889
Spectrum of Peripheral and Autonomic Neuropathies in Patients With aTTRwt Amyloidosis and Response to Patisiran Therapy
Phase 3Ended 9 Apr 2026
Completed204 participants
NCT06788535
REVEAL - Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosis
No phaseEnded 7 Apr 2026
Completed50 participants
NCT06393465
Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathy
No phaseEnded 30 Mar 2026
Completed250 participants
NCT07585331
Towards Effective, Patient-tailored Anti-plasma Cell Therapies in AL Amyloidosis: Predicting Drug Response and Overcoming Drug Resistance
No phaseEnded 25 Mar 2026
No phaseEnded 16 Mar 2026
Completed15 participants
NCT06372301
Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy
No phaseEnded 13 Mar 2026
No phaseEnded 9 Mar 2026
Completed37 participants
NCT03431896
Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis
No phaseEnded 28 Feb 2026
Completed57 participants
NCT07301892
Generative AI Impact on Rheumatoid Arthritis Complications Diagnosis
No phaseEnded 14 Feb 2026
Phase 2Ended 30 Jan 2026
No phaseEnded 21 Jan 2026
Completed20 participants
NCT03352258
Effect of Low Dose Radiotherapy on Brain Amyloidosis in the Treatment of Alzheimer's Disease
Phase 2Ended 31 Dec 2025
Phase 3Ended 24 Dec 2025
No phaseEnded 4 Dec 2025
Phase 2Ended 29 Nov 2025
No phaseEnded 20 Nov 2025
Completed180 participants
NCT06261216
Association Between Lifetime Physical Activity and Exercise and the Development of Wild-type Transthyretin Amyloid Cardiomyopathy
Phase 3Ended 5 Nov 2025
Completed164 participants
NCT03759379
HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)
- Long-term efficacy and safety of vutrisiran in hereditary transthyretin amyloidosis with polyneuropathy: final analysis of the HELIOS-A randomized treatment extension. · Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 2026
No phaseEnded 13 Oct 2025
Completed13 participants
NCT06321523
A Study to Learn About the Study Medicine Called Tafamidis 61mg in People Diagnosed With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
No phaseEnded 1 Oct 2025
Completed110 participants
NCT04856267
Exploration of Arrhythmia Burden in Cardiac Amyloidosis Using Implantable Loop Recorders
- Exploration of Arrhythmia Burden in Cardiac Amyloidosis Using Implantable Loop Recorders: The EXCALIBUR Study. · Journal of the American College of Cardiology, 2026
No phaseEnded 30 Sept 2025
Completed50 participants
NCT05795400
Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy
Phase 1Ended 30 Sept 2025
Completed96 participants
NCT05661916
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALN-TTRSC04 in Healthy Subjects
Phase 1Ended 12 Sept 2025
Phase 3Ended 21 Aug 2025
Completed25 participants
NCT04622046
A Phase 3 Study of ALXN2060 in Japanese Participants With Symptomatic ATTR-CM
No phaseEnded 10 Aug 2025
No phaseEnded 1 Aug 2025
No phaseEnded Jul 2025
Completed10 participants
NCT01758042
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
No phaseEnded 23 Jul 2025
Completed20143 participants
NCT05557162
Artificial Intelligence Enhanced ECG to Detect Cardiac Amyloidosis
Phase 2Ended 17 Jul 2025
Completed35 participants
NCT04617925
A Study of Belantamab Mafodotin in Patients With Relapsed or Refractory AL Amyloidosis
No phaseEnded 30 Jun 2025
Completed30 participants
NCT04392960
Novel Imaging Tools in Newly-diagnosed Patients With Cardiac AL Amyloidosis
No phaseEnded 12 Jun 2025
Completed721 participants
NCT06414746
Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia
No phaseEnded 6 Jun 2025
Completed6 participants
NCT06086353
A Study to Learn About Tafamidis in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in India
Phase 1/2Ended 26 May 2025
Phase 3Ended 23 May 2025
No phaseEnded 21 May 2025
No phaseEnded 16 May 2025
Completed5028 participants
NCT03237494
TRAMmoniTTR Study Genetic Screening of an At-risk Population for hATTR and Monitoring of TTR Positive Subjects
Phase 2Ended 13 May 2025
No phaseEnded 25 Apr 2025
Phase 1Ended 4 Apr 2025
No phaseEnded 27 Mar 2025
No phaseEnded 10 Feb 2025
Completed67 participants
NCT03616496
Assessment of 18F-Florbetaben Whole-body PET for the Detection of Cardiac and Extracardiac Sites of Amyloid Deposits
Phase 2Ended 27 Jan 2025
Completed40 participants
NCT04131309
A Study of Daratumumab Monotherapy in Previously Untreated Patients With Stage 3B Light Chain (AL) Amyloidosis
No phaseEnded 31 Dec 2024
No phaseEnded 13 Dec 2024
Completed646 participants
NCT03812172
Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations
Phase 1Ended 2 Dec 2024
No phaseEnded 1 Dec 2024
Completed112 participants
NCT04862273
CMR T1 Mapping for Diagnosis of Cardiac Amyloidosis
- Cardiac magnetic resonance T1 mapping for amyloid cardiomyopathy in patients with heart failure. · European heart journal. Imaging methods and practice, 2026
Phase 3Ended 19 Nov 2024
Phase 1Ended 15 Nov 2024
Completed12 participants
NCT06527755
A Study to Assess the PK, PD, Safety and Tolerability of Eplontersen in Healthy Chinese Volunteers
Phase 1Ended 14 Nov 2024
Completed12 participants
NCT05374564
Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy
Not medical advice. fetched 6 Nov 2026