Colorectal cancer: trials for referral
2193 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
Type a city to sort by distance. The distance is worked out in your browser; the city is not sent anywhere.
400 trials shown · Showing the 400 most recently updated of 2193 open trials.
Phase 1/21 site
RecruitingUnited States
NCT06149481
Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)
National Cancer Institute (NCI)
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 2/31 site
By invitation onlyChina
NCT07927049
Evaluating the Efficacy of Chidamide in the Treatment of Initial Unresectable Metastatic Colorectal Cancer With High Expression of SULF1
Sir Run Run Shaw Hospital
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT01174121
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
National Cancer Institute (NCI)
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govNo phase2 sites
RecruitingFrance
NCT04025541
Analysis of Circulating Tumor Markers in Blood
Institut du Cancer de Montpellier - Val d'Aurelle
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 12 sites
RecruitingUnited States
NCT04222413
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
National Cancer Institute (NCI)
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT04847063
Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies
National Cancer Institute (NCI)
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 2/31 site
By invitation onlyChina
NCT07927075
Evaluating the Efficacy of Chidamide in Advanced Refractory Colorectal Cancer With High SULF1 Expression
Sir Run Run Shaw Hospital
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 116 sites
RecruitingUnited States
NCT06102902
Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
National Cancer Institute (NCI)
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 19 sites
RecruitingGermany, Italy
NCT05492682
START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer
Valo Therapeutics Oy
Registry updated 9 Nov 2026 · The registries disagree on the status
Registry record: ClinicalTrials.govPhase 11 site
Not yet recruitingUnited States
NCT07715903
Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy
National Cancer Institute (NCI)
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 20 sites
Not yet recruiting
NCT07926477
Trastuzumab Rezetecan + Bevacizumab vs. TAS-102 + Bevacizumab in Pretreated mCRC With HER2 Low/Moderate Expression or HER2 Positivity With RAS/BRAF Mutation
Second Affiliated Hospital, Zhejiang University, School of Medicine
Registry updated 9 Nov 2026
Registry record: ClinicalTrials.govPhase 113 sites
RecruitingCanada, South Korea, United States
NCT06983743
A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
Erasca, Inc.
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 1/20 sites
Not yet recruiting
NCT07915921
A Phase Ib/II Study of GFH276 in Combination With Chemotherapy (± Bevacizumab) or Cetuximab in Patients With RAS-mutant Metastatic Colorectal Cancer
Genfleet Therapeutics (Shanghai) Inc.
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 183 sites
RecruitingAustralia, Canada, Germany, Denmark, Spain, United Kingdom
NCT04929223
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Hoffmann-La Roche
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 23 sites
RecruitingNigeria, United States
NCT06529523
Tislelizumab in People With Colorectal Cancer
Memorial Sloan Kettering Cancer Center
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govNo phase46 sites
RecruitingUnited States
NCT06995898
The Vanguard Study: Testing a New Way to Screen for Cancer
National Cancer Institute (NCI)
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 119 sites
RecruitingSpain, France, United States
NCT07318805
A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors
Pfizer
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 35 sites
RecruitingUnited States
NCT07271355
Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial
City of Hope Medical Center
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
Not yet recruitingUnited States
NCT07662031
Tovecimig Plus FOLFIRI in Second Line Metastatic Colorectal Cancer
Washington University School of Medicine
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT04703101
Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer
Jonsson Comprehensive Cancer Center
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 3130 sites
RecruitingArgentina, Austria, Australia, Belgium, Canada, China
NCT07549412
A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
EMD Serono Research & Development Institute, Inc.
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 220 sites
RecruitingUnited States
NCT07446322
FOLFIRI and Bevacizumab With or Without Pelareorep for Second-Line Treatment of Metastatic RAS-Mutated, Microsatellite-Stable Colorectal Cancer
Oncolytics Biotech
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 28 sites
RecruitingPuerto Rico, United States, Vietnam
NCT06824064
Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer
Riboscience, LLC.
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 20 sites
Not yet recruiting
NCT07224022
Cemiplimab With Fianlimab for Resectable Non-Metastatic Colon Cancer
John Strickler, M.D.
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 3207 sites
RecruitingBelgium, Canada, China, Czechia, Germany, Spain
NCT07228832
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Summit Therapeutics
Pre-treatment window Registry sentence: “No prior systemic therapy for metastatic CRC”
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT05411718
A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
M.D. Anderson Cancer Center
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 1/2103 sites
RecruitingBelgium, China, Germany, Spain, France, United Kingdom
NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Boehringer Ingelheim
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT06885697
Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma
National Cancer Institute (NCI)
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 242 sites
RecruitingSpain, Georgia, South Korea, United States
NCT06695845
A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors
Jazz Pharmaceuticals
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 210 sites
RecruitingUnited States
NCT04165772
Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors
Memorial Sloan Kettering Cancer Center
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- United States227 open trials
- China110 open trials
- Spain66 open trials
- France51 open trials
- Australia51 open trials
- Italy45 open trials
- Canada39 open trials
- Germany36 open trials
- South Korea36 open trials
- United Kingdom36 open trials
- Japan34 open trials
- Belgium30 open trials
- Netherlands22 open trials
- Taiwan17 open trials
- Poland16 open trials
- Denmark14 open trials
- Brazil13 open trials
- Israel11 open trials
- Argentina9 open trials
- Puerto Rico9 open trials
- Mexico9 open trials
- Türkiye9 open trials
- Austria8 open trials
- Czechia7 open trials
- Singapore7 open trials
- Sweden7 open trials
- Malaysia6 open trials
- Greece6 open trials
- Chile5 open trials
- Switzerland5 open trials
- Portugal5 open trials
- Hong Kong4 open trials
- Romania4 open trials
- India4 open trials
- Norway4 open trials
- Ireland4 open trials
- Hungary3 open trials
- Georgia3 open trials
- Finland3 open trials
- Colombia2 open trials
- New Zealand2 open trials
- Egypt2 open trials
- Nigeria1 open trial
- Vietnam1 open trial
- Ukraine1 open trial
- Slovakia1 open trial
- Serbia1 open trial
- Panama1 open trial
- Armenia1 open trial
- Uzbekistan1 open trial
- United Arab Emirates1 open trial
- Moldova1 open trial
- Uganda1 open trial
- Bulgaria1 open trial
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Cancer Hospital of Chinese Academy of Medical Sciences
Beijing, China
23 trials · 86 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
Status changed: Running, not recruiting → Completed
The Effect of Art Therapy in Patients Undergoing Colorectal Cancer
NCT07137000 · No phase · Türkiye
Source: ClinicalTrials.govStatus changed: Running, not recruiting → Completed
LEAn Body Mass Normalization of OXaliplatin Based Chemotherapy
NCT03255434 · Phase 2 · France
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
Community Partnership for Telehealth Solutions to Convey Information and Enhance Care
NCT06542835 · No phase · United States
Source: ClinicalTrials.govClosed for recruitment
A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients
NCT07291414 · No phase · United States
Source: ClinicalTrials.govNew in the registry
Nurse-Led Prehabilitation Before Major Abdominal Cancer Surgery
NCT07922642 · No phase · Egypt
Source: ClinicalTrials.govNew in the registry
Outcomes of Knife-Assisted Full-Thickness Resection for Rectal Lesions: A Multicenter Study
NCT07923682 · No phase · Belgium
Source: ClinicalTrials.govNew in the registry
Tailored Nutrition vs. Exercise Prehabilitation Before Colorectal Cancer Surgery
NCT07922850 · No phase · Norway
Source: ClinicalTrials.govNew in the registry
Pre- and On-treatment Multi-omics Profiling of Locally Advanced Rectal Cancer
NCT07920770 · No phase · China
Source: ClinicalTrials.govClosed for recruitment
Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings
NCT05785780 · No phase · United States
Source: ClinicalTrials.govNew in the registry
METIMMOX-3 for patients with recently diagnosed bowel cancer with spread to other organs
2026-526317-29-00 · Phase 2 · Norway
Source: EU CTISNew in the registry
RAPID for Unresectable Colorectal Liver Metastases
NCT07919951 · No phase · China
Source: ClinicalTrials.govStopped early
CT-95 in Advanced Cancers Associated With Mesothelin Expression
NCT06756035 · Phase 1 · United States
Source: ClinicalTrials.govOpened for recruitment
NCT07693751 · Phase 1/2 · Belgium, Czechia, Spain, France, Moldova, United States
Source: ClinicalTrials.govOpened for recruitment
NCT07318805 · Phase 1 · Spain, France, United States
Source: ClinicalTrials.govPhase changed: Phase 1 → Phase 1/2
Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors
NCT07151040 · Phase 1/2 · Spain, France, United Kingdom
Source: ClinicalTrials.gov
Show more
Status changed: Recruiting → Not yet recruiting
NCT07150403 · Phase 2 · France
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
NCT07178717 · Phase 2 · Spain
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
Pre-Operative Treatment in REseCTable COlon CanceR
NCT06899477 · Phase 3 · Germany
Source: ClinicalTrials.govClosed for recruitment
A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors
NCT06607185 · Phase 1 · Belgium, Germany, Spain, France, Italy, Japan
Source: ClinicalTrials.govPhase changed: Phase 1 → Early Phase 1
PET-imaging of Two Vartumabs in Patients With Solid Tumors
NCT06645808 · Early Phase 1 · Netherlands
Source: ClinicalTrials.govOpened for recruitment
PET-imaging of Two Vartumabs in Patients With Solid Tumors
NCT06645808 · Early Phase 1 · Netherlands
Source: ClinicalTrials.govPhase changed: Phase 3 → Phase 2
NCT06614192 · Phase 2 · Australia, Germany, Spain, France, Israel, Italy
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT06614192 · Phase 2 · Australia, Germany, Spain, France, Israel, Italy
Source: ClinicalTrials.govOpened for recruitment
Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI
NCT06501482 · Phase 3 · France
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer
NCT06328738 · Phase 1 · Belgium, Spain, France, Italy, South Korea, Netherlands
Source: ClinicalTrials.govPhase changed: Phase 1/2 → Phase 1
ELVN-002 With Trastuzumab +/- Chemotherapy in HER2+ Solid Tumors, Colorectal and Breast Cancer
NCT06328738 · Phase 1 · Belgium, Spain, France, Italy, South Korea, Netherlands
Source: ClinicalTrials.govOpened for recruitment
Sacituzumab Govitecan in Metastatic Colorectal Cancer
NCT06243393 · Phase 2/3 · Germany
Source: ClinicalTrials.govPhase changed: Phase 1 → Phase 1/2
A First-In-Human Trial of pTTL in Advanced Colorectal Cancer
NCT05908643 · Phase 1/2 · Sweden
Source: ClinicalTrials.govOpened for recruitment
NCT05855200 · Phase 3 · Argentina, Australia, Belgium, Brazil, Canada, China
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
Galunisertib Combined With Capecitabine in Advanced CRC With PM
NCT05700656 · Phase 1/2 · Netherlands
Source: ClinicalTrials.govPhase changed: Phase 1/2 → Phase 1
NCT05668585 · Phase 1 · Germany, Spain, France, United Kingdom, Italy, United States
Source: ClinicalTrials.govOpened for recruitment
START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer
NCT05492682 · Phase 1 · Germany, Italy
Source: ClinicalTrials.govClosed for recruitment
NCT05217446 · Phase 2 · Australia, Belgium, Canada, Czechia, Germany, Denmark
Source: ClinicalTrials.govOpened for recruitment
Nivolumab and Ipilimumab in Anti-PD1-Resistant dMMR/MSI mCRC
NCT05310643 · Phase 2 · France
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
D,L-MEthadone and mFOLFOX6 in Treatment of Advanced Colorectal Cancer
NCT05212012 · Phase 1/2 · Germany
Source: ClinicalTrials.govClosed for recruitment
NCT05029882 · Phase 1 · Australia, Germany, Spain, France, Israel, Japan
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT04895722 · Phase 2 · Belgium, Canada, Colombia, Costa Rica, Germany, Denmark
Source: ClinicalTrials.govPhase changed: Phase 2/3 → Phase 2
NCT04895722 · Phase 2 · Belgium, Canada, Colombia, Costa Rica, Germany, Denmark
Source: ClinicalTrials.govOpened for recruitment
Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome
NCT04920149 · Phase 2 · Denmark, Sweden
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT04793958 · Phase 3 · Argentina, Austria, Australia, Belgium, Brazil, Canada
Source: ClinicalTrials.govOpened for recruitment
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
NCT04557449 · Phase 1/2 · Argentina, China, Czechia, United Kingdom, Japan, Mexico
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT04486378 · Phase 2 · Belgium, Canada, Germany, Spain, United Kingdom, Sweden
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
NCT04083599 · Phase 1/2 · Germany, Denmark, Spain, France, United Kingdom, Georgia
Source: ClinicalTrials.govClosed for recruitment
A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor
NCT04008797 · Phase 1/2 · Canada, China, Denmark, Spain, France, Italy
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT04008030 · Phase 3 · Argentina, Austria, Australia, Belgium, Brazil, Canada
Source: ClinicalTrials.govPhase changed: Phase 1/2 → Phase 1
NCT03715933 · Phase 1 · Spain, France, United Kingdom, Italy, Netherlands, United States
Source: ClinicalTrials.govClosed for recruitment
NCT03869892 · Phase 3 · Argentina, Austria, Australia, Bulgaria, Brazil, Czechia
Source: ClinicalTrials.govPhase changed: Phase 1 → Phase 1/2
NCT03732781 · Phase 1/2 · Norway, Sweden
Source: ClinicalTrials.govStatus changed: Running, not recruiting → Completed
IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting
NCT02967289 · Phase 3 · Canada, France, Italy
Source: ClinicalTrials.govStatus changed: Running, not recruiting → Completed
NCT02980510 · Phase 2 · France
Source: ClinicalTrials.govClosed for recruitment
LEAn Body Mass Normalization of OXaliplatin Based Chemotherapy
NCT03255434 · Phase 2 · France
Source: ClinicalTrials.govPhase changed: Phase 1/2 → Phase 2
NCT03175224 · Phase 2 · Australia, Canada, Spain, France, United Kingdom, Hungary
Source: ClinicalTrials.govClosed for recruitment
Adjuvant Low Dose Aspirin in Colorectal Cancer
NCT02647099 · Phase 3 · Denmark, Finland, Norway, Sweden
Source: ClinicalTrials.govStatus changed: Running, not recruiting → Completed
Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer
NCT01918527 · Phase 3 · Denmark, Norway, Sweden
Source: ClinicalTrials.govClosed for recruitment
NCT05855200 · Phase 3 · Argentina, Australia, Belgium, Brazil, Canada, China
Source: ClinicalTrials.govStatus changed: Running, not recruiting → Not yet recruiting
Adjuvant Low Dose Aspirin in Colorectal Cancer
NCT02647099 · Phase 3 · Denmark, Finland, Norway, Sweden
Source: ClinicalTrials.govOpened for recruitment
Pre-Operative Treatment in REseCTable COlon CanceR
NCT06899477 · Phase 3 · Germany
Source: ClinicalTrials.govClosed for recruitment
Sacituzumab Govitecan in Metastatic Colorectal Cancer
NCT06243393 · Phase 2/3 · Germany
Source: ClinicalTrials.govOpened for recruitment
A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor
NCT04008797 · Phase 1/2 · Canada, China, Denmark, Spain, France, Italy
Source: ClinicalTrials.govClosed for recruitment
Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI
NCT06501482 · Phase 3 · France
Source: ClinicalTrials.govOpened for recruitment
NCT05217446 · Phase 2 · Australia, Belgium, Canada, Czechia, Germany, Denmark
Source: ClinicalTrials.govClosed for recruitment
Nivolumab and Ipilimumab in Anti-PD1-Resistant dMMR/MSI mCRC
NCT05310643 · Phase 2 · France
Source: ClinicalTrials.govOpened for recruitment
NCT03869892 · Phase 3 · Argentina, Austria, Australia, Bulgaria, Brazil, Czechia
Source: ClinicalTrials.govClosed for recruitment
Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome
NCT04920149 · Phase 2 · Denmark, Sweden
Source: ClinicalTrials.govStatus changed: Running, not recruiting → Not yet recruiting
NCT04730544 · Phase 2 · France
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
NCT07693751 · Phase 1/2 · Belgium, Czechia, Spain, France, Moldova, United States
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
NCT07318805 · Phase 1 · Spain, France, United States
Source: ClinicalTrials.govClosed for recruitment
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
NCT04557449 · Phase 1/2 · Argentina, China, Czechia, United Kingdom, Japan, Mexico
Source: ClinicalTrials.govClosed for recruitment
PET-imaging of Two Vartumabs in Patients With Solid Tumors
NCT06645808 · Early Phase 1 · Netherlands
Source: ClinicalTrials.govOpened for recruitment
NCT05029882 · Phase 1 · Australia, Germany, Spain, France, Israel, Japan
Source: ClinicalTrials.govClosed for recruitment
START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer
NCT05492682 · Phase 1 · Germany, Italy
Source: ClinicalTrials.govOpened for recruitment
A Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors
NCT06607185 · Phase 1 · Belgium, Germany, Spain, France, Italy, Japan
Source: ClinicalTrials.govNew in the registry
Indocyanine Green Lymphatic Mapping in Minimally Invasive Sigmoid and Rectal Cancer Surgery
NCT07916532 · No phase · Poland
Source: ClinicalTrials.govNew in the registry
Real-World Study: Panitumumab N01 vs Cetuximab Plus FOLFOX in First-Line RAS Wild-Type mCRC
NCT07917429 · No phase · China
Source: ClinicalTrials.govStopped early
KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer
NCT05985109 · Phase 2 · China
Source: ClinicalTrials.govStopped early
ctDNA and Organ Preservation/Pathologic CR in Rectal Cancer
NCT05629442 · No phase
Source: ClinicalTrials.govStatus changed: Running, not recruiting → Completed
Impact of Protect Your Colon™ on CRC Screening
NCT05929820 · No phase · United States
Source: ClinicalTrials.govClosed for recruitment
The Effect of Music During Colonoscopy
NCT07454993 · No phase · Denmark
Source: ClinicalTrials.gov
New reviews, guidelines and randomised trials in PubMed
Meta-analysis
Journal of robotic surgery · PubMed
Systematic review
BMC cancer · PubMed
Meta-analysis
Langenbeck's archives of surgery · PubMed
Systematic review
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · PubMed
Systematic review
Frontiers in medicine · PubMed
Systematic review
Frontiers in oncology · PubMed
Meta-analysis
Arquivos de gastroenterologia · PubMed
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
Phase 2Ended 20 Oct 2026
Completed16 participants
2023-509088-26-00
Single arm phase II study of ctDNA-guided encorafenib plus cetuximab retreatment in patients with BRAF V600E mutated mCRC. BRICKET study
Phase 2Ended 20 Oct 2026
Completed16 participants
NCT06578559
Phase II Study of ctDNA-guided Encorafenib Plus Cetuximab Retreatment in Patients BRAF V600E Mutated mCRC
No phaseEnded 14 Oct 2026
Phase 1Ended 9 Oct 2026
Stopped early19 participants
NCT06756035
CT-95 in Advanced Cancers Associated With Mesothelin Expression
Reason given: The study was halted prematurely and will not resume; participants are no longer receiving intervention or undergoing evaluations. The termination was not due to any safety or efficacy concerns.
No phaseEnded 3 Oct 2026
Phase 2Ended 1 Oct 2026
Withdrawn before start0 participants
NCT05518032
Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC)
Reason given: prioritization of studies
Phase 1/2Ended 1 Oct 2026
Stopped early194 participants
NCT04868877
Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination
Reason given: The Sponsor terminated the trial early for strategic business reasons. This isn't related to any safety/efficacy/clinical activity/benefit-risk concern with petosemtamab. Ongoing participants will have access to treatment outside of this trial.
No phaseEnded Sept 2026
Completed1115 participants
NCT02966483
Transanal Versus Laparoscopic Total Mesorectal Excision For Rectal Cancer
No phaseEnded 30 Sept 2026
Completed29 participants
NCT07916532
Indocyanine Green Lymphatic Mapping in Minimally Invasive Sigmoid and Rectal Cancer Surgery
Phase 2Ended 30 Sept 2026
Stopped early20 participants
NCT05985109
KN 046 Plus Regorafenib in MSS Metastatic Colorectal Cancer
Reason given: The study was stopped early due to lack of efficacy.
Early Phase 1Ended 30 Sept 2026
Withdrawn before start0 participants
NCT04870034
Binimetinib and Palbociclib Before Surgery for the Treatment of Operable KRAS-Positive Lung, Colorectal, or Pancreatic Cancer
Reason given: Issues recruiting
Phase 2Ended 29 Sept 2026
Completed94 participants
2025-523984-39-00
Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults with Advanced Colorectal Cancer.
Phase 1/2Ended 28 Sept 2026
Stopped early74 participants
NCT05358249
Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation
Reason given: Business reasons and not based on any safety concerns.
No phaseEnded 25 Sept 2026
Paused90 participants
NCT04392050
A Community-Based Educational Intervention to Improve Colorectal Cancer Screening
Reason given: staffing
Phase 1Ended 24 Sept 2026
No phaseEnded 15 Sept 2026
Phase 4Ended 9 Sept 2026
No phaseEnded 5 Sept 2026
Completed160 participants
NCT06668402
Study of Daily Step Count and Treatment Response in Rectal Cancer (STEP-R)
Phase 2Ended 4 Sept 2026
Withdrawn before start0 participants
NCT07720115
Phase 2 Trial Of S-531011 With RadScopal In Previously Treated Metastatic Colorectal Cancer
Reason given: 0 participants
No phaseEnded 1 Sept 2026
Show more
No phaseEnded 31 Aug 2026
Completed2527 participants
NCT06790355
ProSight: A Multi-centre Interventional Study Evaluating MCED in Asymptomatic Population
No phaseEnded 31 Aug 2026
Completed98 participants
NCT04722341
Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators
- The CHRONO trial: Protocol for a randomized controlled trial of early time-restricted eating in patients with breast or rectal cancer. · Nutrition research (New York, N.Y.), 2026
No phaseEnded Aug 2026
No phaseEnded 24 Aug 2026
Completed103 participants
NCT05487248
A Study of On-treatment ctDNA Changes in Chemo-refractory Colorectal Cancer Patients
No phaseEnded 21 Aug 2026
Paused1000000 participants
NCT05506800
Guangzhou Women's Health Cohort Study (GWHCS)
Reason given: Due to the rebound of the COVID-19 epidemic in the city, we have to suspend the project temporarily.
Phase 1/2Ended 21 Aug 2026
Completed55 participants
NCT04708470
A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers
Phase 2Ended 20 Aug 2026
Stopped early39 participants
NCT04898504
HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden.
Reason given: Following temporary halt of inclusion in September 2024, several measures were taken, as previuosly reported. As numbers included by September 2024 were sufficient to conclude for primary endpont, we have decided not to restart the trial.
No phaseEnded 19 Aug 2026
No phaseEnded 14 Aug 2026
Completed70 participants
NCT07882069
Effect of ACTIVE-Care on Cancer-Related Fatigue, Hope, and Psychological Resilience in Adolescents With Acute Lymphoblastic Leukemia
Phase 2Ended 11 Aug 2026
Completed21 participants
2023-503228-17-00
Intratumoral Flu Vaccine and Pembrolizumab in Colorectal Cancer
No phaseEnded 10 Aug 2026
Phase 3Ended 10 Aug 2026
Phase 1Ended 7 Aug 2026
Withdrawn before start0 participants
NCT05737615
PET Imaging Using 64Cu-Tz-SarAr and hu5B1-TCO in People With Pancreatic, Colorectal, Bladder Cancer or Cancers With Elevated CA19.9
Reason given: Study tracer is currently unavailable
Phase 4Ended 1 Aug 2026
Completed44 participants
NCT06115174
Clinical Study Evaluating the Anticancer Effect of Pentoxiphylline in Patients With Metastatic Colorectal Cancer
Phase 1Ended 31 Jul 2026
No phaseEnded 31 Jul 2026
Completed80 participants
NCT06593678
Telerehabilitation in Cancer Patients: Optimization of Prehabilitation and Rehabilitation Following Colorectal Resection
No phaseEnded Jul 2026
Withdrawn before start0 participants
NCT06796049
Behavioral Nudge in Colorectal Cancer Screening
Reason given: Study was discontinued due to a lack of feasibility.
No phaseEnded 28 Jul 2026
Completed13 participants
NCT05785780
Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings
Phase 1Ended 22 Jul 2026
Stopped early38 participants
NCT03203525
Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer
Reason given: \<75% participation
Phase 1Ended 22 Jul 2026
Completed77 participants
NCT06131398
A Study of AMG 355 Alone and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors
No phaseEnded 20 Jul 2026
Completed95 participants
NCT04287218
Reducing Fear of Cancer Recurrence in Danish Colorectal Cancer Survivors
- E-Health Intervention for Fear of Cancer Recurrence: A Randomized Clinical Trial. · JAMA network open, 2025
Phase 1Ended 16 Jul 2026
Completed138 participants
NCT03872947
A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors
No phaseEnded 16 Jul 2026
Phase 3Ended 13 Jul 2026
Stopped early21 participants
NCT07152821
Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma
Reason given: Pharmaceutical Sponsor discontinued trial financial support
No phaseEnded 10 Jul 2026
Completed47 participants
NCT06199232
Targeted Treatment Plus Tislelizumab and HAIC for Advanced CRCLM Failed From Standard Systemic Treatment
Phase 1Ended 8 Jul 2026
Completed27 participants
NCT06399757
A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors
Phase 1Ended 3 Jul 2026
Completed40 participants
2024-519301-36-00
A study to test different doses of BI 765049 in people with advanced cancer of the colon, rectum, stomach, or pancreas
No phaseEnded 1 Jul 2026
Phase 2Ended 1 Jul 2026
Completed70 participants
2022-502413-29-00
Multicenter Phase 2 study to evaluate the efficacy and safety of Cetuximab in combination with Encorafenib plus Binimetinib as induction treatment in BRAF (V600E) mutated MSS, initially resectable or potentially resectable advanced colorectal cancer: CEBBRA study.
Phase 2Ended 1 Jul 2026
Paused12 participants
NCT04816045
Neoadjuvant electrochemotherapy for colorectal cancer - a phase 2 trial
No reason given in the registry.
Phase 3Ended Jun 2026
Completed250 participants
NCT01918527
Neoadjuvant Chemotherapy Versus Standard Treatment in Patients With Locally Advanced Colon Cancer
Phase 1Ended 30 Jun 2026
Completed5 participants
NCT06935149
Detecting Colorectal Cancer With Liver Metastatic Lesions Using Novel Precise Imaging Tools
No phaseEnded 30 Jun 2026
No phaseEnded 30 Jun 2026
Completed6129 participants
NCT07718919
Multicentric National Italian Analysis of Textbook Outcome in Colorectal Cancer Surgery
- Staying minimally invasive: robotic versus laparoscopic colorectal cancer surgery in a propensity-weighted Italian multicentre cohort. · Journal of robotic surgery, 2026
No phaseEnded 30 Jun 2026
Stopped early10 participants
NCT05930496
Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors
Reason given: Terminated due to low accrual.
No phaseEnded 30 Jun 2026
Phase 1Ended 30 Jun 2026
Completed58 participants
NCT05396300
A Clinical Study of CEA-targeted CAR-T in the Treatment of CEA-positive Advanced Malignant Solid Tumors
Phase 2Ended 29 Jun 2026
Completed138 participants
NCT02992912
Atezolizumab With Stereotactic Ablative Radiotherapy in Patients With Metastatic Tumours
No phaseEnded 25 Jun 2026
Completed109 participants
NCT07838246
Liquid Biopsy Biomarkers for Endoscopic Surveillance in Lynch Syndrome
No phaseEnded 20 Jun 2026
Not medical advice. fetched 11 Nov 2026