Ulcerative colitis: trials for referral
442 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
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400 trials shown · Showing the 400 most recently updated of 442 open trials.
No phase1 site
RecruitingGermany
NCT07102368
A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany
Janssen-Cilag G.m.b.H
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase0 sites
Not yet recruiting
NCT07746765
A Study of Continued Use of Guselkumab in Participants With Crohn's Disease and Ulcerative Colitis in Real World Setting
Janssen Sciences Ireland UC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited Kingdom
NCT07242248
A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)
Janssen-Cilag Ltd.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 337 sites
RecruitingCzechia, France, United Kingdom, Georgia, Hungary, Poland
NCT06651281
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
Merck Sharp & Dohme LLC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 2175 sites
By invitation onlyArgentina, Austria, Australia, Belgium, Bulgaria, Brazil
NCT07652294
Long-term Safety and Efficacy of Multiple Long-acting Antibodies Alone and in Combinations for IBD
Spyre Therapeutics, Inc.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 41 site
RecruitingUnited States
NCT07654751
A Remotely Conducted Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically
Janssen Research & Development, LLC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT04372108
A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis
Janssen Scientific Affairs, LLC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingAustria
NCT07606339
A Study of Guselkumab in Participants With Crohn's Disease and Ulcerative Colitis
Janssen-Cilag Pharma GmbH
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingSpain
NCT07848737
A Real-World Study of Guselkumab Persistence and Effectiveness in Participants With Crohn's Disease or Ulcerative Colitis
Janssen-Cilag, S.A.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 358 sites
RecruitingArgentina, Australia, Belgium, Brazil, China, Germany
NCT06663332
A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants
Janssen Research & Development, LLC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase11 sites
RecruitingChina
NCT07302360
A Real-World Study of Guselkumab in Chinese Participants With Ulcerative Colitis
Xian-Janssen Pharmaceutical Ltd.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 1/212 sites
RecruitingJapan, United States
NCT07913347
Safety, Dosage, and Microbiome Engraftment Study of MGT-006 for Ulcerative Colitis (ROOT Study)
Metagen Therapeutics, Inc.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 3327 sites
RecruitingArgentina, Austria, Australia, Belgium, Bulgaria, Brazil
NCT07577856
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
Janssen Research & Development, LLC
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT07619547
Longitudinal Immunophenotyping of Patients With Inflammatory Bowel Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govPhase 1/21 site
RecruitingUnited States
NCT03167437
An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab
National Institute of Allergy and Infectious Diseases (NIAID)
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT07501078
Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal Inflammation
Muhammad N Aslam, MD
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 410 sites
RecruitingGermany, Denmark, Spain, Italy, Poland
2025-522362-78-00
A study to measure mirikizumab levels in breast milk of lactating participants receiving mirikizumab therapeutically for an approved indication
Eli Lilly & Co.
Registry updated 30 Oct 2026
Registry record: EU CTISPhase 1/294 sites
RecruitingArgentina, Australia, Bulgaria, Brazil, Canada, Chile
NCT06619990
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
Xencor, Inc.
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govNo phase3 sites
RecruitingUnited States
NCT06810518
ALPCO Calprotectin CLIA Assay - Measurement of Calprotectin Levels in Human Stool
American Laboratory Products Company
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 228 sites
RecruitingChina
NCT07265570
Study Evaluating ISM5411 Administered Orally to Subjects With Active Ulcerative Colitis (BETHESDA)
InSilico Medicine Hong Kong Limited
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 40 sites
Not yet recruiting
NCT07700446
Efficacy of Upadacitinib Re-induction Therapy in Patients With Ulcerative Colitis Who Lost Response to 30 mg Maintenance Dose
Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 413 sites
By invitation onlyUnited States
NCT07686757
INSIGHT-IBD Pragmatic Study
Specialty Networks Research.
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
Not yet recruitingChina
NCT07900945
Study of Single and Multiple Ascending Doses of CM551 in Healthy Participants
Keymed Biosciences Co.Ltd
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingChina
NCT07755241
A Study of AC-101 Tablets in Patients With Ulcerative Colitis
Accro Bioscience (Suzhou) Limited
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingVietnam
NCT07799428
Bacillus Probiotic Spores in Supporting the Treatment of Chronic Inflammatory Bowel Disease
Anabio R&D
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited Kingdom
NCT07747467
A Study to Investigate the Safety and Tolerability of Multiple Study Interventions in Participants With Moderate to Severe Ulcerative Colitis
GlaxoSmithKline
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 4101 sites
RecruitingUnited States
NCT06581328
A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
Takeda
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 2118 sites
RecruitingAustralia, Brazil, Canada, China, Czechia, Germany
NCT06979336
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
Genentech, Inc.
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 2296 sites
RecruitingArgentina, Austria, Australia, Belgium, Bulgaria, Brazil
NCT07012395
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
Spyre Therapeutics, Inc.
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govNo phase6 sites
RecruitingUnited Kingdom
NCT06579443
Robotic Inflammatory Bowel Disease Development, Learning and Efficacy Study
University Hospitals Coventry and Warwickshire NHS Trust
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- United States109 open trials
- China63 open trials
- Poland48 open trials
- Italy46 open trials
- France44 open trials
- Canada42 open trials
- Germany34 open trials
- Belgium29 open trials
- Spain25 open trials
- United Kingdom23 open trials
- Japan22 open trials
- Netherlands21 open trials
- South Korea20 open trials
- Czechia19 open trials
- Romania18 open trials
- Hungary17 open trials
- Australia16 open trials
- Denmark16 open trials
- Greece15 open trials
- Israel14 open trials
- Slovakia13 open trials
- Egypt13 open trials
- Brazil12 open trials
- Austria11 open trials
- Bulgaria11 open trials
- Ukraine10 open trials
- Moldova10 open trials
- Portugal10 open trials
- India10 open trials
- Croatia10 open trials
- Georgia9 open trials
- Serbia9 open trials
- Taiwan9 open trials
- Sweden8 open trials
- Norway7 open trials
- Lithuania6 open trials
- Mexico6 open trials
- Chile6 open trials
- Argentina5 open trials
- Ireland5 open trials
- Jordan4 open trials
- Switzerland4 open trials
- Finland3 open trials
- Puerto Rico3 open trials
- South Africa3 open trials
- Latvia3 open trials
- Russia3 open trials
- Malaysia2 open trials
- Colombia2 open trials
- Thailand2 open trials
- Lebanon1 open trials
- Vietnam1 open trials
- Pakistan1 open trials
- Saudi Arabia1 open trials
- Hong Kong SAR China1 open trials
- New Zealand1 open trials
- Guadeloupe1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Amsterdam UMC Location University of Amsterdam
Amsterdam, Netherlands
3 trials · 46 publications · ROR
Cambridge University Hospitals NHS Foundation Trust
Cambridge, United Kingdom
2 trials · 52 publications · ROR
Centre Hospitalier Régional et Universitaire de Nancy
Nancy, France
30 trials · 130 publications · ROR
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
Madrid, Spain
0 trials · 144 publications · ROR
Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, China
0 trials · 90 publications · ROR
Complejo Hospitalario Universitario de Santiago
Santiago de Compostela, Spain
0 trials · 60 publications · ROR
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
Barcelona, Spain
0 trials · 49 publications · ROR
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
14 trials · 43 publications · ROR
Hospital General Universitario de Alicante Doctor Balmis
Alicante, Spain
2 trials · 68 publications · ROR
Instituto de Investigación Sanitaria del Hospital Universitario de La Princesa
Madrid, Spain
0 trials · 64 publications · ROR
Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL)
Alicante, Spain
0 trials · 48 publications · ROR
National Clinical Research Center for Digestive Diseases
Beijing, China
0 trials · 46 publications · ROR
Nutrition-Génétique et Exposition aux Risques Environnementaux
Vandœuvre-lès-Nancy, France
0 trials · 126 publications · ROR
The First Affiliated Hospital, Sun Yat-sen University
Guangzhou, China
15 trials · 45 publications · ROR
University of North Carolina at Chapel Hill
Chapel Hill, United States
6 trials · 82 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
No registry change in the last 7 days.
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
Phase 2Ended 15 Oct 2026
Phase 1Ended 15 Oct 2026
Completed8 participants
2025-520930-44-00
A Study to Learn How the Study Medicine Called Etrasimod is Taken up Into Blood and Breastmilk of Healthy Breastfeeding Women.
Phase 1Ended 12 Oct 2026
Phase 1Ended 1 Oct 2026
No phaseEnded 30 Sept 2026
Completed8250 participants
NCT01848561
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
Phase 3Ended 29 Sept 2026
Phase 2Ended 21 Sept 2026
Completed280 participants
NCT05611671
A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC
Phase 1Ended 11 Sept 2026
No phaseEnded 10 Sept 2026
Completed238 participants
NCT06587828
A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease
Phase 2Ended 8 Sept 2026
Phase 3Ended 8 Sept 2026
Completed1173 participants
NCT02914535
Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis
No phaseEnded 1 Sept 2026
No phaseEnded 24 Aug 2026
Completed100 participants
NCT06632691
Virtual Reality Headset and Acceptability of Rectosigmoidoscopy in Ulcerative Colitis: a Randomised Controlled Trial
Phase 2/3Ended 20 Aug 2026
Phase 1Ended 18 Aug 2026
Completed24 participants
NCT06693908
A Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulcerative Colitis
No phaseEnded 31 Jul 2026
Completed673 participants
NCT04535882
Effectiveness of Serum Leucine-rich Alpha-2 Glycoprotein Levels on IBD
No phaseEnded 31 Jul 2026
Phase 2Ended 30 Jul 2026
Completed181 participants
NCT06867094
A study to investigate efficacy and safety of SAR441566 in patients with ulcerative colitis
No phaseEnded 5 Jul 2026
No phaseEnded 30 Jun 2026
Completed292 participants
NCT04827368
Volatile Organic Compounds (VOCs) in Active Inflammatory Bowel Disease
No phaseEnded 30 Jun 2026
Completed1006 participants
NCT05626088
A Study in Adults With Inflammatory Bowel Disease (IBD) Receiving Vedolizumab in the Patient Support Program (PSP) in Brazil
No phaseEnded 24 Jun 2026
Completed64 participants
NCT06094608
IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms
Phase 4Ended 11 Jun 2026
Completed32 participants
NCT05313620
Effect of Tofacitinib on Coagulation and Platelet Function, and Its Role in Thromboembolic Events
No phaseEnded 6 Jun 2026
No phaseEnded 1 Jun 2026
Phase 1/2Ended 28 May 2026
Completed128 participants
NCT03847467
Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy
Phase 1/2Ended 4 May 2026
Completed10 participants
NCT05104723
Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications
Phase 3Ended 1 May 2026
Completed63 participants
NCT05784246
A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis
No phaseEnded 1 May 2026
No phaseEnded 30 Apr 2026
Completed60 participants
NCT07269223
Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients
Phase 3Ended 27 Apr 2026
Completed172 participants
NCT05767021
A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis
Phase 1/2Ended 20 Apr 2026
Completed25 participants
NCT07083193
A Study of AC-101 Tablets in Participants With Moderate to Severe Active Ulcerative Colitis
No phaseEnded 15 Apr 2026
Completed121 participants
NCT07089420
ALPCO/Calprotectin CLIA Assay: Expected Values of Calprotectin in Healthy Subjects
No phaseEnded 15 Apr 2026
Completed30 participants
NCT05662059
Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) Study in Ulcerative Colitis
Phase 4Ended 13 Apr 2026
Completed672 participants
NCT04259138
Determination of the Optimal Treatment Target in Ulcerative Colitis
Phase 1Ended 6 Apr 2026
Completed24 participants
NCT07350577
Evaluate the Safety, Tolerability, PK and PD of SAD of Intravenously Adminsterted ALTB-268 in Healthy Participants
Phase 3Ended 1 Apr 2026
No phaseEnded 3 Mar 2026
Completed81 participants
NCT07472309
Effectiveness and Safety of Upadacitinib for Acute Severe Ulcerative Colitis
No phaseEnded 1 Mar 2026
Completed30 participants
NCT05743153
Feasibility of a Multimodal Intervention Program to Optimize Treatment Outcomes in Ulcerative Colitis
No phaseEnded 1 Mar 2026
Completed60 participants
NCT07694362
Narrow Band Imaging Versus Artificial Intelligence for Colonic Surveillance in Inflammatory Bowel Disease
No phaseEnded 28 Feb 2026
No phaseEnded 25 Feb 2026
Phase 4Ended 5 Feb 2026
Completed10 participants
NCT06346288
A Study to Assess the Concentrations of Risankizumab in the Breast Milk of Adult Lactating Women With Inflammatory Bowel Disease
No phaseEnded 9 Jan 2026
Phase 1Ended 8 Jan 2026
Completed29 participants
NCT06582264
A Phase 1b Trial to Evaluate the Safety of MB310 in Patients With Active, Mild-to-Moderate Ulcerative Colitis
Phase 1Ended 8 Jan 2026
Phase 4Ended 6 Jan 2026
Phase 2Ended 5 Jan 2026
Completed252 participants
NCT06049017
A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis
No phaseEnded 1 Jan 2026
Completed282 participants
NCT07695636
Effectiveness and Safety of Mirikizumab in Patients With Moderate-to-severe Ulcerative Colitis: a Real-life Retrospective Multicenter Study
No phaseEnded 31 Dec 2025
Phase 2Ended 18 Dec 2025
No phaseEnded 9 Dec 2025
No phaseEnded 9 Dec 2025
No phaseEnded 8 Dec 2025
Completed152 participants
NCT04424303
Tofacitinib in Adult Patients With Moderate to Severe Ulcerative Colitis
No phaseEnded 4 Dec 2025
Completed66 participants
NCT06316999
Intestinal Ultrasound for the Evaluation of Pouchitis and Other Outcomes After Ileal Pouch-Anal Anastomosis
No phaseEnded 1 Dec 2025
Completed80 participants
NCT07261579
Composite Ratios Boost CRP's Power in Monitoring Ulcerative Colitis.
No phaseEnded 1 Dec 2025
Completed38 participants
NCT06381518
Switching From Intravenous to Subcutaneous Infliximab in Adult Patients With Inflammatory Bowel Disease
No phaseEnded 30 Nov 2025
Completed234 participants
NCT05271773
Impact of Therapeutic Intervention on Quality of Life in Patients With Ulcerative Colitis
Phase 2Ended 26 Nov 2025
Completed93 participants
2023-508679-34-00
Efficacy and Safety of Rosnilimab in Subjects with Ulcerative Colitis
Phase 2Ended 18 Nov 2025
Completed3 participants
NCT03983837
Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous Disease
Not medical advice. fetched 4 Nov 2026