Epilepsy: who works on it

One card per institution. Filter by target, by country, or show only institutions in EU-13 (Horizon Europe widening) countries.

• All targets
• NMDA 0
• mTOR 3
• SCN1A 6
• SCN2A 2
• HMGB1 0
• PPAR 0
• BDNF 1
• NLRP3 0
• TLR4 0
• NRF2 0
• PTEN 0
• AKT 0
• PI3K 0
• IDH 0
• GLP-1 0
• IL-1 1
• JAK 0
• GPX4 0
• AMPK 0
• CTNNB1 1
• MAPK 0
• APOE 0
• COX-2 0
• SGLT2 0
• SIRT1 0
• STING 0
• TNF 0
• ERK 1
• HIF-1 0
• STAT3 0
• TP53 0
• TREM2 0
• CGRP 0
• HDAC 0
• MAPT 0
• YAP 0
• APP 0
• CXCR4 0
• HSP90 0
• IL-6 0
• JNK 0
• MDM2 0
• NOTCH1 0
• NOTCH3 0
• PD-1 0
• PINK1 0
• AQP4 0
• AR 0
• B7-H3 0
• BACE1 0
• BCL-2 0
• BRAF 0
• BRD4 0
• CD47 0
• DMD 0
• DPP-4 0
• FGFR 0
• FTO 0
• G6PD 0
• GBA1 0

EU-13 is a filter, not a ranking: it only narrows the list.

24 of 200+ institutions, ordered by recent publications and open trials. This is not a ranking of quality.

Terminated, withdrawn and suspended trials with the reason the sponsor gave in the registry, quoted word for word.

• Terminated

  Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

  NCT06700811· Heather Olson· Updated 14 Oct 2026

  “The study closed due to recruitment challenges.”Registry text, quoted unchanged. Source

• Terminated

  Identification of Volatile Organic Compounds (VOCs) as Biopredictors of Epileptic Seizures

  NCT05865561· Fondation Ophtalmologique Adolphe de Rothschild· Updated 7 Oct 2026

  “Insufficient enrollement of patients”Registry text, quoted unchanged. Source

• Terminated

  Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery

  NCT06280092· Mayo Clinic· Updated 8 Sept 2026

  “PI has passed away”Registry text, quoted unchanged. Source

• Terminated

  A Study of Soticlestat in Adults and Children With Rare Epilepsies

  NCT03635073· Takeda· Updated 4 Sept 2026

  “Due to negative results from phase 3 SKYLINE and SKYWAY studies and unrelated to patient safety it has been determined that supplementary data from TAK-935-18-001 study is no longer necessary. Therefore, Takeda has made a decision to close this study”Registry text, quoted unchanged. Source

• Terminated

  A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

  NCT05163314· Takeda· Updated 4 Sept 2026

  “Due to negative results from phase 3 SKYLINE and SKYWAY studies and unrelated to patient safety it has been determined that supplementary data from TAK-935-3003 study is no longer necessary. Therefore, Takeda has made a decision to close this study”Registry text, quoted unchanged. Source

• Terminated

  A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

  NCT06422377· Takeda· Updated 4 Sept 2026

  “Business decision unrelated to patient safety.”Registry text, quoted unchanged. Source

• Withdrawn

  A Study on Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) in Children, Teenagers and Adults in Portugal

  NCT06395792· Takeda· Updated 17 Aug 2026

  “Business Decision”Registry text, quoted unchanged. Source

• Withdrawn

  Sleep Spindles and Memory in Rolandic Epilepsy

  NCT04569708· Massachusetts General Hospital· Updated 7 Aug 2026

  “Subjects were never enrolled and PI moved”Registry text, quoted unchanged. Source

• Suspended

  Risk Factors for Drug-Resistant Epilepsy in Children

  NCT07723287· Pham Ngoc Thach University of Medicine· Updated 23 Jul 2026

  “Study hasn't stopped yet”Registry text, quoted unchanged. Source

• Terminated

  A Clinical Trial of CAP-002 Gene Therapy in Pediatric Patients With Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy

  NCT06983158· Capsida Biotherapeutics, Inc.· Updated 10 Jun 2026

  “Stopping rule for study was met”Registry text, quoted unchanged. Source

Trials whose registry record says individual participant data (IPD) will be shared.

• Training Program to Improve EEG Competence

  NCT07689084· University Hospital Marburg· Source

• ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome

  NCT07531745· Ionis Pharmaceuticals, Inc.· Source

• Behavioral and Neuronal Correlates of Human Mood States

  NCT06159595· Stanford University· Source

• A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic Epilepsy

  NCT07723963· Jazz Pharmaceuticals· Source

• A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

  NCT04666610· UCB Biopharma SRL· Source

• Lily's Grace Temporal Interference

  NCT07520955· University of Wisconsin, Madison· Source

• High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 Years

  NCT07803692· Oregon Health and Science University· Source

• Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

  NCT01793168· Sanford Health· Source

• Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG)

  NCT05944692· CREmedical· Source

• A Study to Investigate the Effect of Gradual Titration to Optimize Cannabidiol Treatment in Adults With LGS

  NCT07728097· Jazz Pharmaceuticals· Source

Find publications on this disease by a MeSH method term, for example a sequencing or imaging method.

• Single-Cell Analysis 8
• Organoids 13
• Mendelian Randomization Analysis 36
• CRISPR-Cas Systems 9
• Gene Expression Profiling 28
• Sequence Analysis, RNA 4
• Whole Genome Sequencing 14
• Exome Sequencing 114
• Proteomics 23
• Metabolomics 23
• Mass Spectrometry 7
• Flow Cytometry 3
• Immunohistochemistry 21
• Liquid Biopsy 1
• Xenograft Model Antitumor Assays 2
• Positron-Emission Tomography 67
• Magnetic Resonance Imaging 570
• Machine Learning 111
• Deep Learning 78
• Cohort Studies 312
• Genome-Wide Association Study 37

• Copy number variants across the developmental epilepsy-developmental and epileptic encephalopathy spectrum: an Indonesian case series.

  Neurogenetics, Oct 2026

• PIK3R2-related megalencephaly syndrome: expanded phenotypic spectrum associated with craniosynostosis.

  Orphanet J Rare Dis, Oct 2026

• A novel de novo variant of CDKL5 in an Iranian child with infantile-onset refractory epilepsy.

  Mol Biol Rep, Oct 2026

• Whole-exome sequencing in a Turkish autism spectrum disorder cohort: a retrospective study of molecular diagnostic yield in isolated and complex presentations.

  BMC Psychiatry, Oct 2026

• KATNAL2 dysfunction impairs microtubule dynamics and contributes to syndromic neurodevelopmental disease.

  Hum Mol Genet, Oct 2026

• [Genetic and phenotypic analysis of three children with Neurodevelopmental disorders due to variants of DEAF1 gene].

  Zhonghua Yi Xue Yi Chuan Xue Za Zhi, Oct 2026

• Precision Medicine in Epilepsy: Diagnostic Yield by Next-Generation Sequencing and Genotype-Phenotype Findings in a Romanian Cohort.

  Int J Mol Sci, Oct 2026

• A De Novo Arg649Trp Variant in GluA2 Impairs Its Assembly With GluA1: Associated With Epilepsy and Neurodevelopmental Disorders.

  Hum Mutat, Oct 2026

• FOXG1 syndrome: genetic background revealed by trio WES in case of a critically ill neonate.

  Ideggyogy Sz, Sept 2026

• Zygosity-Dependent Phenotypic Spectrum of RELN-Related Disorders: 10 New Patients and Genotype-Phenotype Correlations Across 48 Kindreds.

  Hum Mutat, Sept 2026

See which targets of this disease your abstract mentions, and go to the people working on them.