Atrial fibrillation: open trials in United Kingdom

• NCT05976685

  Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy

  Trial Treatment · Insel Gruppe AG, University Hospital Bern

  Addenbrooke's Hospital, Cambridge · St Thomas Hospital, London · St. Bartholomew's Hospital, London · Charing Cross Hospital, London · University Hospitals Sessex NHS Trust, Worthing

  Registry updated 2026-11-06

• NCT07217067

  A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation

  Trial Treatment · Phase 2 · Novartis Pharmaceuticals

  Brighton · Liverpool · London · Newcastle upon Tyne

  Registry updated 2026-10-28

• NCT07900685

  A Comparison of Pulsed Field Ablation (PFA) vs Cryoablation for Atrial Fibrillation Under Deep Sedation

  Trial Treatment · East Sussex Healthcare NHS Trust

  Eastbourne DGH, Eastbourne

  Registry updated 2026-10-28

• NCT06951100

  Mechanisms of Myocardial Injury and Ischemia in Patients With Rapid Atrial Fibrillation

  Research · University of Edinburgh

  Royal Infirmary of Edinburgh, Edinburgh

  Registry updated 2026-10-26

• NCT07523620

  Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration

  Trial Treatment · Abbott Medical Devices

  Royal Sussex County Hospital, Brighton · John Radcliffe Hospital, Oxford

  Registry updated 2026-10-23

• NCT06393920

  PulseSelect™ PFA Global Registry

  Research · Medtronic Cardiac Ablation Solutions

  University Hospitals Coventry & Warwickshire, Coventry · Saint Georges University Hospitals - NHS Trust, London

  Registry updated 2026-10-16

• NCT07852221

  Patient Selection and Long-Term Outcomes of Pace & Ablate Strategy in Atrial Fibrillation

  Research · Insel Gruppe AG, University Hospital Bern

  Liverpool Heart and Chest Hospital, Liverpool

  Registry updated 2026-10-01

• NCT06096246

  Investigation of Cardioversion Versus Therapeutic Ablation for Persistent AF (ORBICA-AF)

  Trial Treatment · Barts & The London NHS Trust

  Barts Heart Centre, London

  Registry updated 2026-09-22

• NCT05963698

  The Fourth Left Atrial Appendage Occlusion Study

  Trial Treatment · Hamilton Health Sciences Corporation

  University Hospitals Coventry and Warwickshire, Coventry · University Hospitals of Leicester NHS Trust, Leicester · Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool · Nottingham University Hospital NHS Trust, Nottingham · Oxford University Hospitals NHS Foundation Trust, Oxford · University Hospital Southampton NHS Foundation Trust, Southampton · University Hospitals Sussex NHS Trust, Worthing

  Registry updated 2026-09-18

• NCT07454135

  Mechanisms of Atrial Pathoelectrophysiology in HCM

  Research · Guy's and St Thomas' NHS Foundation Trust

  Guy's and St Thomas' NHS Foundation Trust, London

  Registry updated 2026-09-11

• NCT07436299

  Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation

  Research · Oslo University Hospital

  Department of Cardiovascular Sciences, University of Birmingham, Birmingham · King's College, London

  Registry updated 2026-09-10

• NCT05920824

  Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation

  Research · Barts & The London NHS Trust

  St. Bartholomew's Hospital, London

  Registry updated 2026-07-16

• NCT05712200

  Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

  Trial Treatment · Phase 3 · Anthos Therapeutics, Inc.

  Blackpool · Bollington · Brierley Hill · Corby · Glasgow · Glasgow · Hayle · High Wycombe · Isleworth · Kings Lynn · Lancaster · Larbert · Leeds · Liverpool · London · London · London · London · Luton · Manchester · Newcastle upon Tyne · Norwich · Oxford · Peterborough · Romford · Stevenage · Stockton-on-Tees · Stoke-on-Trent · Taunton

  Registry updated 2026-07-13

• NCT04045665

  Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

  Trial Treatment · Phase 3 · Icahn School of Medicine at Mount Sinai

  Belfast Health and Social Care Trust, Belfast · Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool · University Hospitals Bristol NHS Foundation Trust, Bristol · Royal Papworth Hospital NHS Foundation Trust, Cambridge · Hull University Teaching Hospitals NHS Trust, Cottingham · University Hospitals of Leicester NHS Trust, Leicester · Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool · Imperial College Healthcare NHS Trust, London · Barts Health NHS Trust, London · South Tees Hospitals NHS Foundation Trust, Middlesbrough · Nottingham University Hospitals NHS Trust, Nottingham · Oxford University Hospitals NHS Foundation Trust, Oxford · University Hospitals Plymouth NHS Trust, Plymouth · Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield · University Hospital Southampton NHS Foundation Trust, Southampton · Royal Wolverhampton Nhs Trust, Wolverhampton · University Hospitals Sussex NHS Foundation Trust, Worthing

  Registry updated 2026-06-26

• NCT06165510

  Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation

  Trial Treatment · Barts & The London NHS Trust

  St. Bartholomew's Hospital, London

  Registry updated 2026-06-25

• NCT07454317

  Biofeedback Intervention for Paroxysmal Atrial Fibrillation

  Trial Treatment · Liverpool John Moores University

  Liverpool John Moores University, Liverpool

  Registry updated 2026-05-22

• NCT05633303

  Personalised Ablation Strategies in AF

  Trial Treatment · Barts & The London NHS Trust

  Barts Heart Centre, Barts Health NHS trust, London

  Registry updated 2026-05-08

• NCT05955365

  Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation

  Trial Treatment · Phase 4 · Insel Gruppe AG, University Hospital Bern

  Imperial College London, London

  Registry updated 2026-05-08

• NCT07574697

  AIC Genotyping Study

  Research · Barts & The London NHS Trust

  St Bartholomew's Hospital, Barts Health NHS Trust, London

  Registry updated 2026-05-08

• NCT06505798

  Cryoballoon/Radiofrequency/Pulsed Field Ablation of Atrial Fibrillation Versus Medical Treatment for Heart

  Trial Treatment · University College, London

  Mid and South Essex NHS Foundation Trust, Basildon · Queen Elizabeth Hospital, Birmingham · Blackpool Victoria Hospital, Blackpool · University Hospitals Dorset NHS Foundation Trust, Bournemouth · Royal Papworth Hospital NHS Foundation Trust, Cambridge · University Hospitals Coventry and Warwickshire NHS Trust, Coventry · Golden Jubilee National Hospital, Glasgow · Hull University Teaching Hospitals NHS Trust, Hull · Leeds Teaching Hospitals NHS Trust, Leeds · Glenfield Hospital, Leicester · Liverpool Heart and Chest Hospital NHS Foundation Trust, Liverpool · Royal Brompton and Harefields Hospitals, London · St Thomas Hospital, London · Imperial College Healthcare NHS Trust, London · St. George's University Hospitals NHS Foundation Trust, London · Barts Health NHS Trust, London · James Cook University Hosptial, Middlesbrough · Freeman Hospital, Royal Victoria Infirmary, Newcastle · Nottingham University Hospital NHS Trust, Nottingham · University Hospitals Plymouth NHS Trust, Plymouth · Queen Alexandra Hospital, Portsmouth · Southampton General, Southampton · Swansea Bay University Health Board, Swansea

  Registry updated 2026-05-04

• NCT04664686

  Rate or Rhythm Control in CRT: the RHYTHMIC Study

  Trial Treatment · Guy's and St Thomas' NHS Foundation Trust

  Guys and St Thomas NHS Foundation Trust, London

  Registry updated 2026-01-26

• NCT03968393

  Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress

  Trial Treatment · Phase 4 · Population Health Research Institute

  Liverpool Heart and Chest Hospital, Liverpool · Southend Hospital, Westcliff-on-Sea

  Registry updated 2026-01-12

• NCT06324188

  Early Atrial Fibrillation Ablation for Stroke Prevention in Patients With High Comorbidity Burden (EASThigh-AFNET 11)

  Trial Treatment · Atrial Fibrillation Network

  Multiple Locations

  Registry updated 2026-01-08

• NCT06152406

  Ablate and Pace HIS Study

  Trial Treatment · University Hospitals, Leicester

  University Hospitals of Leicester NHS Trust, Leicester

  Registry updated 2026-01-05

• NCT05411614

  Hybrid Ablation of Atrial Fibrillation in Heart Failure

  Trial Treatment · St. George's Hospital, London

  Ashford & St Peters Hospital NHS Trust, Chertsey · Epsom General Hospital, Epsom · St Georges at Kingston Hospital, London · St Georges University of London, London · Royal Surrey County Hospital, London · Cromwell Hospital, London · St Anthonys Hospital, London

  Registry updated 2025-11-28

All Atrial fibrillation trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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