COPD: open trials in Italy

31 open trials have a site in Italy. Registry data; only the trial team decides who can take part.

2025-522359-24-00
The MAB Trial: A Study of Tozorakimab to Reduce Lung Inflammation and Promote Lung Healing in People with COPD.
Trial Treatment · Phase 2 · University Of Leicester
Azienda Socio Sanitaria Territoriale Santi Paolo E Carlo, Milan
Registry updated 2026-10-26
NCT07363694
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Trial Treatment · Phase 2/3 · Pfizer
Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, Bergamo · Azienda Ospedaliero-Universitaria Policlinico G. Rodolico-San Marco Di Catania, Catania · Università degli Studi di Ferrara, Ferrara · Azienda Socio Sanitaria Territoriale Santi Paolo E Carlo, Milan · Azienda Ospedaliera dei Colli, Naples · Azienda USL IRCCS di Reggio Emilia, Reggio Emilia · Azienda Ospedaliero-Universitaria Policlinico Umberto I, Rome
Registry updated 2026-10-22
NCT07587658
This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization
Trial Treatment · Phase 4 · Regeneron Pharmaceuticals
University Hospital Of Ferrara, Ferrara · IRCCS Azienda Ospedaliera Metropolitana, Genoa · Humanitas Mirasole S.p.A., Rozzano
Registry updated 2026-10-16
2026-525216-34-00
A Randomized, Double-Blind, Placebo-controlled, Parallel Arm, 52-week Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of Two Doses of EXPD-101 in Participants with COPD
Trial Treatment · Phase 2 · Expedition Therapeutics Inc.
Azienda Ospedaliero-Universitaria Di Bologna IRCCS Istituto Di Ricerca E Di Cura A Carattere Scientifico, Bologna · University Hospital Of Ferrara, Ferrara · ASST Fatebenefratelli Sacco, Milan · Azienda Ospedaliero Universitaria Pisana, Pisa
Registry updated 2026-10-05
NCT06961214
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Trial Treatment · Phase 3 · GlaxoSmithKline
Azienda Universitaria Ospedaliera Consorziale Policlinico Bari, Bari · Azienda Ospedaliero-Universitaria Policlinico G. Rodolico-San Marco Di Catania, Catania · University Hospital Of Ferrara, Ferrara · Azienda Ospedaliero Universitaria Ospedali Riuniti, Foggia · IRCCS Ospedale Policlinico San Martino, Genoa · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Università Campus Bio-Medico di Roma, Rome · Azienda Ospedaliero-Universitaria Policlinico Umberto I, Rome · Humanitas Mirasole S.p.A., Rozzano · Istituti Clinici Scientifici Maugeri S.p.A. Societa' Benefit In Forma Abbreviata Istituti Clinici Scientifici Maugeri S.p.A. Sb O Anche Ics Maugeri S.p.A. Sb O Maugeri S.p.A. Sb, Telese Terme
Registry updated 2026-10-05
NCT06283966
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Trial Treatment · Phase 3 · AstraZeneca
I.N.R.C.A. Istituto Nazionale di Riposo E Cura Per Gli Anziani, Ancona · Careggi University Hospital, Florence · IRCCS Ospedale Policlinico San Martino, Genoa · Ospedale dell'Angelo di Mestre, Mestre (VE) · Multimedica S.p.A., Milan · Azienda Ospedaliero - Universitaria di Modena, Modena · Azienda Ospedaliera dei Colli, Naples · Fondazione IRCCS Policlinico San Matteo, Pavia · Azienda Unita Sanitaria Locale Umbria 1, Perugia · Azienda Ospedaliero-Universitaria Policlinico Umberto I, Rome · Azienda Ospedaliera Policlinico Universitario Tor Vergata, Rome · Azienda Ospedaliero-Universitaria Sant Andre, Rome · Fondazione Policlinico Universitario Campus Bio-Medico, Rome · Azienda Ospedaliera Universitaria Senese, Siena · Azienda Ospedaliera Ospedale Di Circolo E Fondazione Macchi, Varese
Registry updated 2026-10-02
NCT06035120
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
Trial Treatment · Pulmonx Corporation
ASST Spedali Civili, University Hospital, Brescia
Registry updated 2026-09-17
NCT06883305
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Trial Treatment · Phase 3 · AstraZeneca
University Hospital Of Ferrara, Ferrara · Azienda Ospedaliero-Universitaria Careggi, Florence · Azienda Unita' Locale Socio Sanitaria N. 2 Marca Trevigiana, Montebelluna · Azienda Ospedaliera dei Colli, Naples · Fondazione IRCCS Policlinico San Matteo, Pavia · Fondazione Policlinico Universitario Campus Bio-medico In Forma A Bbreviata Fon, Rome · Azienda Ospedaliero-Universitaria di Sassari, Sassari · Istituti Clinici Scientifici Maugeri S.p.A. Societa' Benefit In Forma Abbreviata Istituti Clinici Scientifici Maugeri S.p.A. Sb O Anche Ics Maugeri S.p.A. Sb O Maugeri S.p.A. Sb, Telese Terme · Istituti Clinici Scientifici Maugeri S.p.A. Societa' Benefit In Forma Abbreviata Istituti Clinici Scientifici Maugeri S.p.A. Sb O Anche Ics Maugeri S.p.A. Sb O Maugeri S.p.A. Sb, Tradate
Registry updated 2026-09-03
NCT07177339
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Trial Treatment · Phase 3 · GlaxoSmithKline
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia, Brescia · University Hospital Of Ferrara, Ferrara · Azienda Ospedaliera dei Colli, Naples · Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome · Azienda Sanitaria Locale Di Taranto, Taranto
Registry updated 2026-07-28
NCT07707245
Identification of Diagnostic and Prognostic Biomarkers in the Pathological Continuum of Bronco Chronic Obstructive Pulmonary Disease, Idiopathic Pulmonary Fibrosis and Pulmonary Neoplasia
Trial Treatment · Fondazione Don Carlo Gnocchi ETS
IRCCS Fondazione Don Carlo Gnocchi, Milan
Registry updated 2026-07-16
NCT05708443
Effect of Combined Endurance Training on ADL and Walking in COPD Patients
Trial Treatment · Istituti Clinici Scientifici Maugeri SpA
ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Lumezzane, Lumezzane · ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Montescano, Montescano · ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate, Tradate
Registry updated 2026-06-24
NCT07665931
Effect of Simeox® on Residual Volume in COPD Patients With Pulmonary Hyperinflation
Trial Treatment · Azienda Socio Sanitaria Territoriale di Lodi
ASST Lodi - Presidio Ospedaliero di Codogno, Codogno
Registry updated 2026-06-24
NCT05008081
The CATALINA Study
Research · Wim Janssens
University Hospital Of Ferrara, Ferrara
Registry updated 2026-05-22
NCT06533371
Clinical-ultrasonographic Assessment of Pulmonary Emphysema
Trial Treatment · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ente Ecclesiastico Ospedale Generale Regionale F Miulli, Acquaviva Delle Fonti · A.O.R.N. "A. Cardarelli", Naples · Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome · University of Trento, Trento
Registry updated 2026-05-22
NCT06068647
Ultrasound and Respiratory Physiological Signals in Lung Diseases
Trial Treatment · Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome
Registry updated 2026-05-20
NCT05381415
Effect on Bronchodilation Response and Ventilation Heterogeneity of Different Inhalation Volumes in COPD
Research · University of Milan
L. Sacco Hospital, Milan
Registry updated 2026-05-04
NCT06652776
The Italian Registry of Patients With Chronic Obstructive Pulmonary Disease
Research · University of Milan
Luigi Sacco University Hospital, Division of Department of Biomedical and Clinical Sciences, University of Milan, Milan
Registry updated 2026-05-04
NCT04238221
Effect of add-on Doxofylline on Lung Function in Stable COPD
Trial Treatment · Phase 4 · University of Milan
L. Sacco Hospital, Milan
Registry updated 2026-04-29
NCT07329946
Immuno-inflammatory Response of Erdosteine in COPD
Trial Treatment · Phase 4 · Pierachille Santus, MD, PhD
ASST Fatebenefratelli Sacco, Milan
Registry updated 2026-04-29
NCT03799354
Study on Impact of Maximal Strength Training in Patients With COPD
Trial Treatment · Istituti Clinici Scientifici Maugeri SpA
ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Lumezzane, Lumezzane
Registry updated 2026-02-23
NCT05720780
Rehabilitation Training With Music-support & Exercise Tolerance in COPD and CRF Patients.
Trial Treatment · Istituti Clinici Scientifici Maugeri SpA
ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Bari, Bari · ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Lumezzane, Lumezzane · ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Montescano, Montescano · ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Pavia, Pavia · ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Telese, Telese Terme · ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate, Tradate
Registry updated 2026-02-23
NCT07414108
How Nocturnal Hypoventilation Predicts Long-term Response to Non-invasive Ventilation in Hypercapnic COPD Patients
Research · IRCCS Azienda Ospedaliero-Universitaria di Bologna
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna
Registry updated 2026-02-17
NCT07302425
High-intensity Resistance Training in Post-exacerbation COPD
Trial Treatment · Istituti Clinici Scientifici Maugeri SpA
ICS Maugeri IRCCS, Respiratory Rehabilitation of the Institute of Lumezzane, Lumezzane
Registry updated 2025-12-24
NCT06800586
Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects
Research · IRCCS Azienda Ospedaliero-Universitaria di Bologna
Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna · Respiratory and Critical Care Unit, IRCCS Azienda Ospedaliera-Universitaria di Bologna, Bologna · Ematology Unit, Azienda Ospedaliero-Universitaria, Policlinico Riuniti di Foggia, Foggia
Registry updated 2025-12-19
2024-517613-33-00
A two-center, randomized, double-blind, placebo-controlled study of intravenous plasma-purified alpha-1 antitrypsin for hospitalized patients with COPD exacerbations (AECOPD study)
Trial Treatment · Phase 2 · Fondazione IRCCS Policlinico San Matteo
Fondazione IRCCS Policlinico San Matteo, Pavia · Humanitas Mirasole S.p.A., Rozzano
Registry updated 2025-10-13

All COPD trials and the map

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