Epilepsy trials in France
47 of 79 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.
- Phase 1/2Not yet taking people in FranceAAV9-ASAH1 intracisterna magna Gene Therapy (GNT0009) in Patients with Spinal Muscular Atrophy with Progressive Myoclonic Epilepsy (SMA - PME)
- Where
- Le Kremlin Bicetre Cedex, Paris
- Age
- Up to 17 years
- People
- 3
- Run by
- Genethon
See details and how to join2026-527323-10-00 - Phase 3Taking peopleA Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
- Where
- Bron, Lille Cedex, Paris, Rennes, Strasbourg Cedex 2
- Age
- 12 years and over
- People
- 160 worldwide
- Run by
- Xenon Pharmaceuticals Inc.
See details and how to joinNCT05667142 · EU 2022-502286-16-00 - Phase 3Taking peopleA Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
- Where
- Bron, Lille Cedex, Paris, Rennes, Strasbourg Cedex 2
- Age
- 18 years and over
- People
- 360 worldwide
- Run by
- Xenon Pharmaceuticals Inc.
See details and how to joinNCT05716100 · EU 2022-502281-25-00 - Phase 3Enrolling by invitationAn Open-label Study of XEN1101 in Epilepsy
- Where
- Bron, Lille Cedex, Paris, Rennes, Strasbourg Cedex 2
- Age
- 12 years and over
- People
- 880 worldwide
- Run by
- Xenon Pharmaceuticals Inc.
See details and how to joinNCT05718817 · EU 2022-502282-24-00 - No phaseTaking peopleStudy of the Link Between Structural Alterations in the Hypothalamus and Cardiac Dysautonomia in Drug-resistant Epilepsy
- Where
- Amiens
- Age
- 18 years and over
- People
- 20
- Run by
- Centre Hospitalier Universitaire, Amiens
See details and how to joinNCT07888543 - No phaseTaking peopleContribution of Fast-ripples to the Improvement of the Neurosurgical Management of Drug-refractory Epilepsy
- Where
- Amiens, Bordeaux, La Tronche, Le Kremlin-Bicêtre, Lille, Lyon, Nancy, Paris, Rennes, Strasbourg, Toulouse
- Age
- 18 years to 65 years
- People
- 440
- Run by
- University Hospital, Toulouse
See details and how to joinNCT06105645 - Phase 3Enrolling by invitationA Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)
- Where
- Bron, Lille, Marseille, Paris, Strasbourg, Toulouse
- Age
- 2 years to 66 years
- People
- 324 worldwide
- Run by
- Longboard Pharmaceuticals
See details and how to joinNCT06908226 · EU 2024-514974-39-00 - Phase 1/2Taking peopleA First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy
- Where
- Marseille, Paris
- Age
- 2 years to 12 years
- People
- 20 worldwide
- Run by
- Institut de Recherches Internationales Servier
See details and how to joinNCT07227857 · EU 2024-513332-17-00 - No phaseTaking peopleImpact of Epilepsy on the Brainstem Adenosine Pathway and Its Relation With Arousal and Respiratory Reactivity
- Where
- Bron
- Age
- 18 years to 55 years
- People
- 50
- Run by
- Hospices Civils de Lyon
See details and how to joinNCT07249034 - No phaseTaking peopleImpact of Canine Mediation Practice in Psychomotor Therapy on Improving the Quality of Life in Adult Epileptic Patients.
- Where
- Saint-Étienne-de-Saint-Geoirs, Tain-l'Hermitage
- Age
- 18 years and over
- People
- 76
- Run by
- Fondation Ophtalmologique Adolphe de Rothschild
See details and how to joinNCT06898749 - Phase 2Taking peopleEfficacy of Probenecid on Cluster Seizures During Anti Seizure Medication Withdrawal in Presurgical Focal Epilepsy Video-EEG Monitoring
- Where
- Paris
- Age
- 6 years to 50 years
- People
- 600
- Run by
- Fondation Ophtalmologique Adolphe de Rothschild
See details and how to joinNCT07318870 - Phase 2Taking peopleEfficacy of probenecid on cluster seizures during dosage reduction of Anti Seizure Medication (ASM) in presurgical focal epilepsy video-EEG monitoring
- Where
- Bron, Grenoble Cedex 9, Lille Cedex, Marseille, Paris, Rennes, Rouen Cedex, Toulouse
- Age
- Up to 64 years
- People
- 192
- Run by
- Fondation A De Rothschild
See details and how to join2024-519133-29-00 - No phaseTaking peopleMulti-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients
- Where
- Paris
- Age
- 18 years and over
- People
- 80
- Run by
- Institut National de la Santé Et de la Recherche Médicale, France
See details and how to joinNCT04653012 - No phaseTaking peopleIntracranial CArtography of Cortical Contribution to Respiratory Load Compensation in Epilepsy
- Where
- Bron
- Age
- 18 years to 55 years
- People
- 20
- Run by
- Hospices Civils de Lyon
See details and how to joinNCT07599150 - Phase 3Not yet taking people in FranceEfficacy of FLUOXETINE in children with drug-resistant, complex and rare epilepsy (FLUOXEPIL)
- Where
- Bordeaux, Lyon Cedex 04, Marseille, Montpellier Cedex 5, Paris, Toulouse Cedex 9
- Age
- Up to 17 years
- People
- 100
- Run by
- Centre Hospitalier Regional De Marseille
See details and how to join2024-519897-38-01 - Phase 3Not yet taking people in FranceCOMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
- Where
- Paris
- Age
- 2 years and over
- People
- 438 worldwide
- Run by
- Yale University
See details and how to joinNCT07281027 - Phase 2Not yet taking people in FranceA Multicenter, Open-Label, Long-Term, Safety and Tolerability Extension Study of PTI5803 as adjunctive therapy in patients ≥ 14 years of age with drug-resistant seizures associated to focal cortical dysplasia.
- Where
- Bron, Marseille, Paris, Tain-L'hermitage
- Age
- Up to 64 years
- People
- 15
- Run by
- PannTheraPi
See details and how to join2026-525161-40-00 - Phase 3Taking peopleA Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures
- Where
- Loos
- Age
- 1 month and over
- People
- 70 worldwide
- Run by
- UCB Biopharma SRL
See details and how to joinNCT04715646 - Phase 2Not yet taking people in FranceA Phase 2a, multi centric, open label clinical study to explore the safety and tolerability, the pharmacokinetics and pharmacodynamics profile and first signs of efficacy of PTI5803 administered as adjunctive therapy with a 3-dose escalation regimen in patients >= 14 years of age with drug-resistant seizures associated to focal cortical dysplasia, followed by an optional open-label extension study.
- Where
- Bron, Marseille, Paris, Tain-L'hermitage
- Age
- Up to 64 years
- People
- 15
- Run by
- PannTheraPi
See details and how to join2026-525162-21-00 - No phaseTaking peopleMultimodal Study of the Human Brain Epilepsy Tissue
- Where
- Paris
- Age
- 18 years and over
- People
- 300
- Run by
- Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06022055 - No phaseTaking peopleRisk Prevention Program and Therapeutic Patient Education Program of Patients With Uncontrolled Epilepsy
- Where
- Montpellier, Toulouse
- Age
- 18 years to 60 years
- People
- 74
- Run by
- University Hospital, Montpellier
See details and how to joinNCT06202196 - No phaseTaking peopleBiomarkers of Response to SEEG Thermocoagulation
- Where
- Marseille
- Age
- 12 years and over
- People
- 45
- Run by
- Assistance Publique Hopitaux De Marseille
See details and how to joinNCT07399327 - Phase 2Not yet taking people in FranceFluorescence Guided Focal Cortical Dysplasia Surgery
- Where
- Bron
- Age
- 3 years and over
- People
- 5
- Run by
- Hospices Civils de Lyon
See details and how to joinNCT07657975 · EU 2025-523608-64-00 - No phaseTaking peopleStudy of Pathophysiology of Status Epilepticus and Dysimmune Encephalitis
- Where
- Paris
- Age
- 2 years and over
- People
- 400
- Run by
- Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT04421846 - No phaseTaking peopleA PET-MRI Study of Serotoninergic Brainstem Pathway in Patients With Dravet Syndrome
- Where
- Bron
- Age
- 18 years to 60 years
- People
- 30
- Run by
- Hospices Civils de Lyon
See details and how to joinNCT07013331