Epilepsy trials in United States

In United States 208 Also abroad 452

208 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Not yet taking people in United States
COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
Where
Aurora, Boston, Chicago, Cincinnati, Cleveland, Dallas, Evanston, Gainesville, Houston, Lincoln, Madison, Milwaukee, New Haven, New York, Philadelphia, Phoenix, Portland, Rochester, Seattle, Washington D.C.
Age
2 years and over
People
438 worldwide
Run by
Yale University
See details and how to joinNCT07281027
No phaseTaking people
Brain Development Research Program
Where
San Francisco
People
2,000
Run by
University of California, San Francisco
See details and how to joinNCT00305305
Phase 2Not yet taking people in United States
Electrophysiologic Mechanisms of Ketamine Antidepressant Response
Where
Atlanta
Age
18 years and over
People
37
Run by
Emory University
See details and how to joinNCT07768618
No phaseNot yet taking people in United States
Acute Stimulation and Modulation of Stereotyped High-Frequency Oscillations
Where
Houston, Rochester
Age
3 years to 70 years
People
8
Run by
Mayo Clinic
See details and how to joinNCT06898138
No phaseTaking people
Subcortical Arousal in Perceptual Awareness
Where
Boston, Houston, Kansas City, Lebanon, Nashville, New Haven, Pittsburgh, Rochester
Age
13 years and over
People
202
Run by
Yale University
See details and how to joinNCT06934356
No phaseTaking people
Sleep Architecture & Cognition in Focal Epilepsy
Where
Sacramento
Age
18 years to 40 years
People
40
Run by
University of California, Davis
See details and how to joinNCT05794295
No phaseEnrolling by invitation
Neuronal and Network Mechanisms of Electrocortical Stimulation
Where
Baltimore, Chicago, Iowa City
Age
18 years to 80 years
People
65
Run by
Northwestern University
See details and how to joinNCT06391294
No phaseTaking people
Implementation and Cost Evaluation of Project UPLIFT
Where
Atlanta
Age
18 years and over
People
60
Run by
Emory University
See details and how to joinNCT06865820
No phaseTaking people
Comparative Effectiveness of Palliative Surgery Versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome
Where
Ann Arbor, Chicago, Columbus, St Louis
Age
Up to 26 years
People
4,680
Run by
Ann & Robert H Lurie Children's Hospital of Chicago
See details and how to joinNCT05374824
No phaseEnrolling by invitation
Temporally Interfering Electric Field Stimulation in the Treatment of Epilepsy
Where
Atlanta, Sacramento
Age
18 years and over
People
100 worldwide
Run by
University of California, Davis
See details and how to joinNCT06716866
No phaseEnrolling by invitation
EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment
Where
Chicago
Age
2 years to 35 years
People
20
Run by
University of Chicago
See details and how to joinNCT07555171
Phase 4Taking people
Outcomes After Planned Discontinuation of AntiSeizure Medication
Where
Ann Arbor
Age
18 years and over
People
40
Run by
University of Michigan
See details and how to joinNCT07750496
Phase 3Taking people
A Clinical Trial of Elsunersen in Pediatric SCN2A-DEE to Assess Efficacy and Safety
Where
Aurora, Chicago, Cincinnati, Memphis, Philadelphia, San Diego
Age
1 day to 18 years
People
40 worldwide
Run by
Praxis Precision Medicines
See details and how to joinNCT07019922
Phase 3Enrolling by invitation
Clinical Trial of Vormatrigine in Adult Patients With Epilepsy
Where
Amherst, Bethesda, Chesterfield, El Paso, Hackensack, Houston, Lafayette, Miami, Miami Lakes, Middletown, Naples, New York, Niagara Falls, Philadelphia, Plymouth
Age
18 years to 85 years
People
700 worldwide
Run by
Praxis Precision Medicines
See details and how to joinNCT07287163
No phaseTaking people
SLC6A1-NDD Prospective Longitudinal Natural History Study
Where
New York
Age
Up to 17 years
People
60 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT07531511
No phaseTaking people
B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy
Where
Durham
Age
18 years and over
People
50
Run by
Duke University
See details and how to joinNCT07271966
Phase 4Taking people
Medication Treatment of ADHD in Pediatric Epilepsy
Where
Baltimore
Age
6 years to 17 years
People
25
Run by
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
See details and how to joinNCT07594652
Phase 3Taking people
A Study to Test the Safety and Tolerability of Brivaracetam in Children and Adolescents With Seizures
Where
Durham, Hawthorne
Age
1 month and over
People
70 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT04715646
No phaseTaking people
Neural Mechanisms of Spatial Representations Beyond the Self
Where
Boston
Age
18 years to 70 years
People
60
Run by
Boston University Charles River Campus
See details and how to joinNCT05406349
No phaseNot yet taking people in United States
A Device to Prevent Sudden Unexpected Death in Epilepsy: Detecting Peri-Ictal Body Position
Where
Boston
Age
18 years and over
People
50
Run by
Brigham and Women's Hospital
See details and how to joinNCT06135285
No phaseTaking people
VNS Algorithm for Advanced Dosing
Where
Augusta
Age
18 years to 75 years
People
80
Run by
Fernando Vale
See details and how to joinNCT07725601
No phaseTaking people
Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight
Where
Boston, Lewisburg
People
100,000
Run by
Simons Searchlight
See details and how to joinNCT01238250
No phaseEnrolling by invitation
Neural Computations of Goal-directed Decision-making
Where
Los Angeles
Age
18 years to 65 years
People
50
Run by
Cedars-Sinai Medical Center
See details and how to joinNCT06489561
Early phase 1Not yet taking people in United States
Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation
Where
Dallas
Age
18 years to 70 years
People
30
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07721272
Phase 4Taking people
The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome Project
Where
Houston
Age
16 years and over
People
25
Run by
The University of Texas Health Science Center, Houston
See details and how to joinNCT07112365