Heart failure trials in United States

In United States 386 Also abroad 1261

386 trials · From ClinicalTrials.gov, checked 10 Nov 2026. Ask the study team whether a trial fits you.

No phaseRecruitingResearch participation
Peripheral Venous Pressure (PVP) Trial
Where
Milwaukee
Age
18 years and over
People
600
Run by
Wake Forest University Health Sciences
See details and how to joinNCT07400042Registry updated 2026-10-07
No phaseRecruitingResearch participation
MOVE-HF MOtivating Physical Activity With BehaVioral Economics in Heart Failure With Preserved Ejection Fraction
Where
Philadelphia
Age
18 years and over
People
270
Run by
University of Pennsylvania
See details and how to joinNCT06670001Registry updated 2026-10-06
No phaseRecruitingResearch participation
Alleviant ALLAY-HFrEF Study
Where
Abilene, Asheville, Austin, Boston, Browns Mills, Charleston, Cleveland, Decatur, Delray Beach, Durham, Englewood, Harrisburg, Houma, Knoxville, Las Vegas, Los Angeles, Minneapolis, Naperville, New Orleans, New York, Pensacola, Plano, Raleigh, Rapid City, Roanoke, Rochester, Sacramento, San Diego, San Francisco, St Louis, Tampa, Temple, Toledo, Waco
Age
18 years and over
People
350 worldwide
Run by
Alleviant Medical, Inc.
See details and how to joinNCT06812533Registry updated 2026-10-06
No phaseRecruitingResearch participation
Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
Where
Bethesda
Age
7 years to 100 years
People
5,000
Run by
National Heart, Lung, and Blood Institute (NHLBI)
See details and how to joinNCT03581318Registry updated 2026-10-05
Phase 3RecruitingTrial-stage medicine
Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure
Where
Pasadena
Age
18 years and over
People
1,900 worldwide
Run by
Pharmacosmos A/S
See details and how to joinNCT06929806EU 2024-519059-28-00Registry updated 2026-10-05
Phase 2RecruitingTrial-stage medicine
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
Where
Abington, Amarillo, Aurora, Birmingham, Camp Hill, Covina, Dallas, Denison, Detroit, Durham, Falls Church, Houston, La Jolla, Louisville, Miami Lakes, Minneapolis, Nashville, New York, Norfolk, Northridge, Orlando, Portland, San Francisco, St Louis, Torrance, Tucson, Winter Park
Age
40 years to 84 years
People
200 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT06979362EU 2024-515796-35-00Registry updated 2026-10-05
No phaseEnrolling by invitationResearch participation
Novel On-body Evaluation of Cardiac Health for Oncology
Where
Albany, Clearwater, Germantown, Golden, Houma, Jacksonville, Littleton, Naperville, Richmond, Rochester, Yardley
Age
18 years and over
People
1,000
Run by
Skribe Medical
See details and how to joinNCT07158450Registry updated 2026-10-05
No phaseRecruitingResearch participation
Early Feasibility Study - Edwards APTURE Transcatheter Shunt System
Where
Aurora, Charleston, Charlotte, Cincinnati, Columbus, Indianapolis, Jacksonville, Kansas City, La Jolla, Los Angeles, Minneapolis, Morristown, Portland, Rochester, San Francisco, Seattle, The Bronx, Tulsa, Wynnewood
Age
18 years and over
People
90
Run by
Edwards Lifesciences
See details and how to joinNCT03523416Registry updated 2026-10-02
Phase 1Not yet recruitingTrial-stage medicine
[11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction
Where
Stony Brook
Age
50 years to 75 years
People
18
Run by
Stony Brook University
See details and how to joinNCT07856043Registry updated 2026-10-02
Phase 1RecruitingTrial-stage medicine
A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
Where
Charleston, Rochester, San Diego
Age
18 years to 65 years
People
8
Run by
Rocket Pharmaceuticals Inc.
See details and how to joinNCT07137338Registry updated 2026-10-01
Phase 1RecruitingTrial-stage medicine
A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
Where
Bradenton, Inverness, Jacksonville, Miami Lakes, Winter Park
Age
18 years to 100 years
People
12 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07465653Registry updated 2026-10-01
No phaseRecruitingResearch participation
Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure
Where
Pleasanton
Age
18 years and over
People
400
Run by
Kaiser Permanente
See details and how to joinNCT07467668Registry updated 2026-10-01
No phaseNot yet recruitingResearch participation
Digital Outreach for Heart Failure Adherence
Where
Pleasanton
Age
18 years and over
People
13,714
Run by
Kaiser Permanente
See details and how to joinNCT07831538Registry updated 2026-10-01
No phaseNot yet recruitingResearch participation
Clinical Evidence With Biomarker Confirmation for PPMI in PCI Clinical Trials Study
Where
Boston
Age
18 years and over
People
1,000
Run by
Baim Institute for Clinical Research
See details and how to joinNCT07848529Registry updated 2026-09-30
No phaseRecruitingResearch participation
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
Where
Boston, Chicago, Philadelphia, Rochester, Sacramento, Winston-Salem
Age
30 years and over
People
1,000
Run by
Northwestern University
See details and how to joinNCT05873634Registry updated 2026-09-29
No phaseRecruitingResearch participation
Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF
Where
Boston
Age
40 years and over
People
136
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT05934565Registry updated 2026-09-29
No phaseRecruitingResearch participation
Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
Where
Baltimore, Boston, Chicago, Philadelphia, Rochester, Winston-Salem
Age
30 years and over
People
180
Run by
Northwestern University
See details and how to joinNCT06517186Registry updated 2026-09-29
No phaseRecruitingResearch participation
NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study
Where
Dallas
People
300
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT06593327Registry updated 2026-09-29
No phaseNot yet recruitingResearch participation
Boston Medical Center Ultrasound Decongestion Study in Heart Failure
Where
Boston
Age
18 years and over
People
200
Run by
Boston Medical Center
See details and how to joinNCT07096726Registry updated 2026-09-29
No phaseRecruitingResearch participation
BiVACOR® Total Artificial Heart Early Feasibility Study
Where
Cincinnati, Durham, Houston, Phoenix
Age
18 years to 70 years
People
20
Run by
BiVACOR Inc.
See details and how to joinNCT06174103Registry updated 2026-09-28
No phaseNot yet recruitingResearch participation
Dietary Tracking in Heart Failure
Where
Cleveland
Age
18 years and over
People
60
Run by
The Cleveland Clinic
See details and how to joinNCT07649148Registry updated 2026-09-28
No phaseNot yet recruitingResearch participation
Wearable Technology in Heart Failure Patients
Where
Cleveland
Age
18 years to 85 years
People
500
Run by
The Cleveland Clinic
See details and how to joinNCT07650669Registry updated 2026-09-28
Phase 3RecruitingTrial-stage medicine
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
Where
Anchorage, Annapolis, Arlington, Atlanta, Baltimore, Bethlehem, Beverly Hills, Bossier City, Boston, Bradenton, Bridgeton, Bridgewater, Brooklyn, Buffalo, Burlington, Champaign, Chapel Hill, Chicago, Colorado Springs, Columbus, Covington, Dallas, Dayton, DeSoto, Durham, East Providence, El Paso, Fairhope, Fargo, Flint, Gilbert, Grand Forks, Greensboro, Gurnee, Hallandale, Houston, Humble, Huntington Beach, Huntington Park, Indianapolis, Jacksonville, Kansas City, Kingwood, Lafayette, Lakeland, Lanham, Leavenworth, Lincoln, Loma Linda, Lomita, Mather, Maumee, Media, Melrose Park, Miami, Miami Lakes, Millville, Moline, Morgantown, New Bedford, New Haven, New Orleans, New York, Niles, Northridge, Ocala, Ocoee, Oklahoma City, Owensboro, Oxon Hill, Palmetto Bay, Palo Alto, Philadelphia, Plano, Rapid City, Redding, Redmond, Riverview, Rockford, Rosedale, San Antonio, San Diego, Schaumburg, Sewell, Shreveport, Smithfield, Southfield, Spartanburg, Statesville, Sun City, Tampa, Tarzana, The Bronx, Tomball, Trenton, Troy, Tucker, Tyler, Victoria, Vineland, Waterloo, Wichita, Wilmington, Winfield, Worcester, Yardley, Zachary
Age
18 years and over
People
6,950 worldwide
Run by
AstraZeneca
See details and how to joinNCT07761117EU 2026-526304-79-00Registry updated 2026-09-28
Phase 1RecruitingTrial-stage medicine
: Vascular Function in Health and Disease
Where
Salt Lake City
Age
18 years and over
People
420
Run by
D. Walter Wray
See details and how to joinNCT02966665Registry updated 2026-09-25
Phase 4RecruitingTrial-stage medicine
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure
Where
Charlotte, Columbus, Philadelphia
Age
18 years to 130 years
People
60 worldwide
Run by
AstraZeneca
See details and how to joinNCT06651970Registry updated 2026-09-24

All Heart failure trials and the map

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