Long COVID and ME/CFS trials in United States

In United States 68 Also abroad 176

68 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1Taking people
Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease
Where
Boston
Age
18 years to 60 years
People
40
Run by
Stephanie B. Seminara, MD
See details and how to joinNCT07224490
No phaseTaking people
Dietary Intervention to Mitigate Post-Acute COVID-19 Syndrome
Where
Baltimore
Age
50 years to 94 years
People
56
Run by
University of Maryland, Baltimore
See details and how to joinNCT05977179
No phaseTaking people
Water-based Activity to Enhance Recovery in Long COVID-19
Where
Palo Alto
Age
18 years to 89 years
People
50
Run by
VA Office of Research and Development
See details and how to joinNCT06142253
Phase 2/3Not yet taking people in United States
A Multi-Center, Individually-Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Superiority Trial to Evaluate the Efficacy of the Combination of Maraviroc and Atorvastatin for the Treatment of Subjects With Long COVID
Where
Tucson
Age
18 years to 65 years
People
252
Run by
HealthBio, Inc.
See details and how to joinNCT06974084
No phaseEnrolling by invitation
Blood-Brain Barrier Integrity and Immune Dynamics in Neuropsychiatric Sequelae of Post-SARS-CoV-2 Onset ME/CFS Versus Pre-Pandemic ME/CFS Patients
Where
Baltimore
Age
18 years to 70 years
People
200
Run by
Johns Hopkins University
See details and how to joinNCT07256795
No phaseTaking people
Non-invasive Treatment for Long COVID (Post COVID-19 Condition) Brain Fog
Where
Scottsdale
Age
18 years and over
People
45
Run by
Mayo Clinic
See details and how to joinNCT06614309
No phaseEnrolling by invitation
Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID
Where
Rochester
Age
18 years and over
People
40
Run by
Mayo Clinic
See details and how to joinNCT06560554
Phase 1Taking people
Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.
Where
Birmingham
Age
18 years to 65 years
People
120
Run by
University of Alabama at Birmingham
See details and how to joinNCT03759522
No phaseTaking people
Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation
Where
Baltimore, San Antonio
Age
Up to 80 years
People
150
Run by
VA Office of Research and Development
See details and how to joinNCT05880108
No phaseTaking people
A Study Of Remote Voice Analysis Tool For Diagnosing And Monitoring ME/CFS
Where
Rochester
Age
18 years and over
People
40
Run by
Mayo Clinic
See details and how to joinNCT07551999
Early phase 1Taking people
Multiparametric [18F]F-AraG Imaging in Post-Acute Sequelae of COVID-19 (PASC)
Where
Sacramento, San Francisco
Age
18 years and over
People
51
Run by
University of California, Davis
See details and how to joinNCT07076862
No phaseTaking people
Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development
Where
New Orleans
Age
6 months to 120 years
People
2,000
Run by
Tulane University
See details and how to joinNCT04956445
No phaseEnrolling by invitation
Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions
Where
Incline Village, Palo Alto, Rochester, Salt Lake City, Seattle
Age
18 years to 65 years
People
150
Run by
Simmaron Research Inc.
See details and how to joinNCT06257420
Phase 3Taking people
Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19
Where
New York
Age
18 years and over
People
80
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT06960928
Phase 2Enrolling by invitation
DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury
Where
Ithaca
Age
18 years to 70 years
People
20
Run by
Leading Edge Clinic
See details and how to joinNCT07567274
Phase 2Taking people
A Study to Assess Anktiva in Patients With Long Covid-19.
Where
San Francisco
Age
18 years to 70 years
People
20
Run by
ImmunityBio, Inc.
See details and how to joinNCT07108036
No phaseTaking people
Cognitive-Sensorimotor Function in Long-COVID
Where
Chicago
Age
18 years and over
People
136
Run by
VA Office of Research and Development
See details and how to joinNCT06850350
No phaseTaking people
A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae
Where
Rochester
Age
18 years and over
People
67
Run by
Mayo Clinic
See details and how to joinNCT06006884
No phaseNot yet taking people in United States
Harnessing Optimism and Perseverance in the Face of Long COVID-Español
Where
New York
Age
18 years and over
People
25
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07216040
Phase 2/3Taking people
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT for Long COVID)
Where
Charleston
Age
18 years to 65 years
People
145
Run by
Medical University of South Carolina
See details and how to joinNCT05855369
No phaseTaking people
Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans
Where
Mountain Home, Portland
Age
18 years to 80 years
People
200
Run by
VA Office of Research and Development
See details and how to joinNCT06932237
No phaseNot yet taking people in United States
Understanding the Long-term Impact of COVID-19 in Adults
Where
New York
Age
18 years to 100 years
People
5,205
Run by
NYU Langone Health
See details and how to joinNCT07498504
Phase 1/2Taking people
Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Where
New York
Age
18 years and over
People
120
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT06511050
Phase 2Taking people
Antiviral Clinical Trial for Long Covid-19
Where
New York
Age
18 years and over
People
90
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT06511063
No phaseTaking people
Chronic Infections and Inflammation in ME/CFS: An Observational Study
Where
San Francisco
Age
18 years and over
People
200
Run by
University of California, San Francisco
See details and how to joinNCT07227441