Ulcerative colitis trials in Italy

In Italy 49 Also abroad 381

49 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
Where
Bergamo, Bologna, Florence, Milan, Roma, Rome
Age
2 years to 19 years
People
150 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT04844606
No phaseNot yet taking people in Italy
Development of the SC-IBD Self-Care Measurement Scale
Where
Roma
Age
18 years and over
People
275
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT07494227
No phaseNot yet taking people in Italy
Ex Vivo Comparison Of Combination Versus Single Therapeutic Pathway Inhibition In Human Intestinal Mucosa From Patients With Inflammatory Bowel Disease
Where
Milan
Age
18 years and over
People
30
Run by
PhoenixLAB srls
See details and how to joinNCT07824726
No phaseNot yet taking people in Italy
Evaluation of the Effects of Colipral on Microbiota Gut Composition in Patients Presenting With Ulcerative Colitis During Remission Phase and Functional Disorders
Where
Padova
Age
18 years to 70 years
People
50
Run by
University of Padova
See details and how to joinNCT07751081
Phase 3Taking people
A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease
Where
Messina, Milan, Pescara, Rome
Age
2 years to 17 years
People
70 worldwide
Run by
Takeda
See details and how to joinNCT06100289 · EU 2023-503188-40-00
No phaseNot yet taking people in Italy
TOLerogenic Potential of Hematopoietic Stem and Progenitor Cells and Inflammatory Bowel Disease
Where
Milan, Rome
Age
2 years to 18 years
People
80
Run by
IRCCS San Raffaele
See details and how to joinNCT07740499
No phaseTaking people
A Specific Probiotic in thE MOdulation of Gut Microbiota of patieNts With Mild-to-modErate Ulcerative Colitis
Where
Roma
Age
18 years to 80 years
People
20
Run by
Catholic University of the Sacred Heart
See details and how to joinNCT07724990
Phase 2Taking people
A Phase 2 Platform Study to Evaluate Therapies for Inflammatory Bowel Disease
Where
Milan, Rome, Rozzano, Turin
Age
18 years and over
People
54 worldwide
Run by
Mirador Therapeutics Inc.
See details and how to join2025-522001-38-00 · EU 2025-522001-38-00
No phaseTaking people
Evaluation of the Accuracy of Immunostaining of Claudin 2 to Detect Active or Inactive Inflammation in Endoscopic Biopsies of IBD
Where
San Donato Milanese
Age
18 years and over
People
100
Run by
IRCCS Policlinico S. Donato
See details and how to joinNCT07710287
No phaseTaking people
Resting Energy Expenditure in Pediatric Patients With Inflammatory Bowel Disease (REE-MICI)
Where
Alessandria
Age
6 years to 17 years
People
50
Run by
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
See details and how to joinNCT07670975
No phaseTaking people
Partial Enteral Nutrition to Prevent Weight Loss and Sarcopenia in IBD Patients at Nutritional Risk - SIMBA
Where
Naples, Pavia, Roma, Rozzano
Age
18 years to 65 years
People
146
Run by
Lionhealth Srl Società Benefit
See details and how to joinNCT07433946
Phase 2Taking people
A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)
Where
Bologna, Milan, Palermo, Rome, Rozzano
Age
18 years to 75 years
People
192 worldwide
Run by
Takeda
See details and how to joinNCT06764615 · EU 2024-518914-18-00
No phaseTaking people
Sodium Butyrate and Kluyveromyces Marxianus Supplementation in Inflammatory Bowel Disease
Where
Padova
Age
18 years to 75 years
People
40
Run by
University of Padova
See details and how to joinNCT07591012
Phase 3Taking people
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Where
Bologna, Florence, Monza, Naples, Rome
Age
2 years to 17 years
People
240 worldwide
Run by
Takeda
See details and how to joinNCT05442567 · EU 2023-509046-36-00
Phase 1/2Taking people
Superdonor FMT in Patients With Ulcerative Colitis
Where
Rome
Age
18 years to 75 years
People
42
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT05739864
Phase 1/2Taking people
FMT in Patients With Recurrent CDI and Ulcerative Colitis: Single Infusion Versus Sequential Approach
Where
Rome
Age
18 years to 75 years
People
64
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT06071312
No phaseEnrolling by invitation
Specimen and Data Collection for a Novel Biomarker Combination for the Differential Diagnosis of Inflammatory Bowel Disease and Irritable Bowel Syndrome.
Where
Milan
Age
2 years and over
People
300 worldwide
Run by
DiaSorin Inc.
See details and how to joinNCT07471490
No phaseTaking people
Impact of Exclusion Diet in Addition to Anti-TNF Therapy in Crohn's Disease and Ulcerative Colitis: a Prospective, Randomized, Double-arm, Open-label Study
Where
Milan
Age
18 years and over
People
80
Run by
IRCCS Ospedale San Raffaele
See details and how to joinNCT06896305
No phaseTaking people
Development of Novel Imaging and Molecular Biomarkers of Fibrosis in Patient With Ulcerative Colitis
Where
Milan
Age
18 years and over
People
50
Run by
IRCCS San Raffaele
See details and how to joinNCT06516237
No phaseTaking people
Spatially and Temporally Resolving Predictive Biomarkers of Postoperative Recurrence and Complications in Chronic Intestinal Inflammation
Where
Milan
Age
18 years to 69 years
People
35
Run by
IRCCS Ospedale San Raffaele
See details and how to joinNCT06516341
No phaseTaking people
Study on Eating Habits and Association with "omic" Profiles in Families with a Subject Affected by a Chronic Immune-mediated Inflammatory Pathology. Observational Multicenter Study.
Where
Florence, Foggia, Palermo, Roma
People
90
Run by
Meyer Children's Hospital IRCCS
See details and how to joinNCT06862843
No phaseTaking people
AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis
Where
Bari, Feltre, Milan, Naples, Pavia
Age
18 years to 75 years
People
300 worldwide
Run by
University College Cork
See details and how to joinNCT06709209
No phaseTaking people
The PODIUM Study - a Three-arm Comparison of Target Therapies After Anti-TNFα in Ulcerative Colitis
Where
Mialn
Age
18 years and over
People
450
Run by
Humanitas Clinical and Research Center
See details and how to joinNCT06691061
No phaseNot yet taking people in Italy
Outcomes of Transanal Tran-section and Single-stapled (TTSS) Ileal Pouch-Anal Anastomosis
Where
Rozzano
Age
18 years and over
People
174
Run by
Istituto Clinico Humanitas
See details and how to joinNCT06331637