Epilepszia: ki dolgozik rajta

Intézményenként egy kártya. Célpontra vagy országra szűkítheted a listát.

• Minden célpont
• NMDA 0
• mTOR 3
• SCN1A 6
• SCN2A 2
• HMGB1 0
• PPAR 0
• BDNF 1
• NLRP3 0
• TLR4 0
• NRF2 0
• PTEN 0
• AKT 0
• PI3K 0
• IDH 0
• GLP-1 0
• IL-1 1
• JAK 0
• GPX4 0
• AMPK 0
• CTNNB1 1
• MAPK 0
• APOE 0
• COX-2 0
• SGLT2 0
• SIRT1 0
• STING 0
• TNF 0
• ERK 1
• HIF-1 0
• STAT3 0
• TP53 0
• TREM2 0
• CGRP 0
• HDAC 0
• MAPT 0
• YAP 0
• APP 0
• CXCR4 0
• HSP90 0
• IL-6 0
• JNK 0
• MDM2 0
• NOTCH1 0
• NOTCH3 0
• PD-1 0
• PINK1 0
• AQP4 0
• AR 0
• B7-H3 0
• BACE1 0
• BCL-2 0
• BRAF 0
• BRD4 0
• CD47 0
• DMD 0
• DPP-4 0
• FGFR 0
• FTO 0
• G6PD 0
• GBA1 0

3088 intézményből 24, a friss publikációk és a nyitott vizsgálatok szerint rendezve. Ez nem minőségi rangsor.

Funded research projects that name this disease in their title, terms or summary and have not ended yet: who is funded, where, how much and until when. Organisations only; the funder's page has the details.

• NIH NIMH · F30

  Neural Correlates of Memory-Based Generalization in Humans

  University of California at Davis· Davis, Egyesült Államok· 43 749 USD awarded in fiscal year 2026· until 2030. szept.

• ALLCDC NCCDPHP · U01

  Epilepsy Incidence Among Children in the United States

  National Opinion Research Center· Chicago, Egyesült Államok· 443 851 USD awarded in fiscal year 2025· until 2030. szept.

• ALLCDC NCCDPHP · U01

  Advancing Understanding of Pediatric Epilepsy Incidence and Risk Factors: A Multilevel Population Health Approach

  Massachusetts General Hospital· Boston, Egyesült Államok· 418 550 USD awarded in fiscal year 2025· until 2030. szept.

• NIH NINDS · F31

  Slow-Wave Sleep Enhancement to Treat Epilepsy

  University of California at Davis· Davis, Egyesült Államok· 43 749 USD awarded in fiscal year 2026· until 2029. szept.

• ALLCDC NCCDPHP · U01

  Incidence and Risk Factors of Childhood Epilepsy in the United States

  Case Western Reserve University· Cleveland, Egyesült Államok· 499 995 USD awarded in fiscal year 2025· until 2030. szept.

• European Commission (Horizon Europe) · HORIZON-ERC

  From single neuron to brain: multi-level strategy and digital twins for personalized prediction of treatment (Neuron2Brain)

  Universita Degli Studi di Genova· Genova, Olaszország· EU contribution 1 500 000 EUR· until 2032. febr.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  Unravelling the Role of Cerebral Amyloid-beta Angiopathy in Epilepsy: Inflammatory Pathways and Interneuron Dysfunction (EPICAA)

  Ludwig-Maximilians-Universitaet Muenchen· Planegg, Németország· EU contribution 217 965 EUR· until 2029. febr.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-GF

  The role of subcortical structures in perceptual consciousness: a causal investigation (StimConscious)

  Katholieke Universiteit Leuven· Leuven, Belgium· EU contribution 424 129 EUR· until 2030. jan.· 3 countries

  The disease is named only in the funder's project summary, not in the title.

• European Commission (Horizon Europe) · HORIZON-ERC-POC

  Standardized patient‑friendly computational language mapping to guide epilepsy surgery (SPEEDY-Clinic)

  Institut National de la Sante Et de la Recherche Medicale· Paris, Franciaország· EU contribution 150 000 EUR· until 2028. jún.

• European Commission (Horizon Europe) · HORIZON-TMA-MSCA-PF-EF

  High-throughput screen for disfunctions in GABA-switch in human neuronal models of SNAREopathies

  Kobenhavns Universitet· Kobenhavn, Dánia· EU contribution 247 553 EUR· until 2028. okt.

  The disease is named only in the funder's project summary, not in the title.

10 of 1267 running projects, newest first. Listed amounts together: 616,7 M USD + 184,0 M EUR.

Sources: NIH RePORTER (U.S. National Institutes of Health, public domain) and CORDIS (European Commission, CC BY 4.0). Changes: filtered by disease, organisations matched to ROR.

Leállított, visszavont és felfüggesztett vizsgálatok, a szponzor által a regiszterben megadott okkal, szó szerint idézve.

• Leállították

  Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

  NCT06700811· Heather Olson· Frissítve: 2026. okt. 14.

  “The study closed due to recruitment challenges.”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  Identification of Volatile Organic Compounds (VOCs) as Biopredictors of Epileptic Seizures

  NCT05865561· Fondation Ophtalmologique Adolphe de Rothschild· Frissítve: 2026. okt. 7.

  “Insufficient enrollement of patients”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery

  NCT06280092· Mayo Clinic· Frissítve: 2026. szept. 8.

  “PI has passed away”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  A Study of Soticlestat in Adults and Children With Rare Epilepsies

  NCT03635073· Takeda· Frissítve: 2026. szept. 4.

  “Due to negative results from phase 3 SKYLINE and SKYWAY studies and unrelated to patient safety it has been determined that supplementary data from TAK-935-18-001 study is no longer necessary. Therefore, Takeda has made a decision to close this study”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

  NCT05163314· Takeda· Frissítve: 2026. szept. 4.

  “Due to negative results from phase 3 SKYLINE and SKYWAY studies and unrelated to patient safety it has been determined that supplementary data from TAK-935-3003 study is no longer necessary. Therefore, Takeda has made a decision to close this study”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  A Study Evaluating Soticlestat in Participants With Dravet Syndrome or Lennox-Gastaut Syndrome Who Have Been Exposed to Fenfluramine

  NCT06422377· Takeda· Frissítve: 2026. szept. 4.

  “Business decision unrelated to patient safety.”A regiszter szövege, változtatás nélkül. Forrás

• Visszavonták

  A Study on Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS) in Children, Teenagers and Adults in Portugal

  NCT06395792· Takeda· Frissítve: 2026. aug. 17.

  “Business Decision”A regiszter szövege, változtatás nélkül. Forrás

• Visszavonták

  Sleep Spindles and Memory in Rolandic Epilepsy

  NCT04569708· Massachusetts General Hospital· Frissítve: 2026. aug. 7.

  “Subjects were never enrolled and PI moved”A regiszter szövege, változtatás nélkül. Forrás

• Felfüggesztve

  Risk Factors for Drug-Resistant Epilepsy in Children

  NCT07723287· Pham Ngoc Thach University of Medicine· Frissítve: 2026. júl. 23.

  “Study hasn't stopped yet”A regiszter szövege, változtatás nélkül. Forrás

• Leállították

  A Clinical Trial of CAP-002 Gene Therapy in Pediatric Patients With Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy

  NCT06983158· Capsida Biotherapeutics, Inc.· Frissítve: 2026. jún. 10.

  “Stopping rule for study was met”A regiszter szövege, változtatás nélkül. Forrás

Vizsgálatok, amelyek regiszteradata szerint az egyéni résztvevői adatokat (IPD) megosztják.

• A Study to Evaluate the Safety and Efficacy of JZP926 Capsule for the Treatment of Juvenile Myoclonic Epilepsy

  NCT07723963· Jazz Pharmaceuticals· Forrás

• Auditory Stimulation Effects on Sleep and Memory in Patients With Epilepsy

  NCT04788628· Massachusetts General Hospital· Forrás

• AAV9-ASAH1 intracisterna magna Gene Therapy (GNT0009) in Patients with Spinal Muscular Atrophy with Progressive Myoclonic Epilepsy (SMA - PME)

  2026-527323-10-00· Genethon· Forrás

• Training Program to Improve EEG Competence

  NCT07689084· University Hospital Marburg· Forrás

• ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome

  NCT07531745· Ionis Pharmaceuticals, Inc.· Forrás

• Behavioral and Neuronal Correlates of Human Mood States

  NCT06159595· Stanford University· Forrás

• A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy

  NCT04666610· UCB Biopharma SRL· Forrás

• Lily's Grace Temporal Interference

  NCT07520955· University of Wisconsin, Madison· Forrás

• High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 Years

  NCT07803692· Oregon Health and Science University· Forrás

• Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

  NCT01793168· Sanford Health· Forrás

Publikációk erről a betegségről egy MeSH-módszerkifejezés szerint, például szekvenálási vagy képalkotó módszerre.

• Single-Cell Analysis 8
• Organoids 13
• Mendelian Randomization Analysis 36
• CRISPR-Cas Systems 9
• Gene Expression Profiling 28
• Sequence Analysis, RNA 4
• Whole Genome Sequencing 14
• Exome Sequencing 114
• Proteomics 23
• Metabolomics 23
• Mass Spectrometry 7
• Flow Cytometry 3
• Immunohistochemistry 21
• Liquid Biopsy 1
• Xenograft Model Antitumor Assays 2
• Positron-Emission Tomography 70
• Magnetic Resonance Imaging 573
• Machine Learning 112
• Deep Learning 78
• Cohort Studies 313
• Genome-Wide Association Study 37

• Ohtahara syndrome in early infancy: A case report and review of the literature.

  Medicine (Baltimore), 2026. nov.

• Resting-State Functional Metrics Associated with Seizure Recurrence After Antiseizure Medication Withdrawal.

  J Vis Exp, 2026. nov.

• Standard anterior temporal lobectomy using a retractorless technique in patients with drug-resistant mesial temporal lobe epilepsy: long-term seizure outcomes and predictors of postoperative seizure freedom.

  Neurosurg Rev, 2026. nov.

• Sphenoidal Meningioma with Focal Seizures Masquerading as Immune Reconstitution Inflammatory Syndrome in HIV Patient.

  Niger Postgrad Med J, 2026. nov.

• Clinical, neurophysiological, and radiological correlates of treatment response in elderly patients with epilepsy.

  Arq Neuropsiquiatr, 2026. okt.

• PIK3R2-related megalencephaly syndrome: expanded phenotypic spectrum associated with craniosynostosis.

  Orphanet J Rare Dis, 2026. okt.

• The electro-MICA toolbox for integrating electrophysiology within multimodal imaging and connectomics workflows.

  Imaging Neurosci (Camb), 2026. okt.

• Normative functional network localization of gray matter alterations in idiopathic generalized epilepsy.

  Front Neurol, 2026. okt.

• [A case of bilateral open-lip schizencephaly with West syndrome due to variant of PAFAH1B1 gene and literature review].

  Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2026. okt.

• [A case of bilateral open-lip schizencephaly with West syndrome due to variant of PAFAH1B1 gene and literature review].

  Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2026. okt.

Megmutatjuk, a betegség mely célpontjait említi az absztrakt, és onnan a rajtuk dolgozókhoz jutsz.