Cystic fibrosis: trials for referral
197 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
Type a city to sort by distance. The distance is worked out in your browser; the city is not sent anywhere.
197 trials shown
Phase 227 sites
RecruitingCzechia, Germany, Spain, France, Israel, Italy
NCT06429176
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis
SpliSense Ltd.
Registry updated 10 Nov 2026
Registry record: ClinicalTrials.govPhase 217 sites
RecruitingItaly, Portugal, United States
NCT07720375
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis
UCB Biopharma SRL
Registry updated 6 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingItaly
NCT07289035
Early Study on Tamoxifen Safety/Tolerability in Cystic Fibrosis Patients Unable to Use CFTR Modulators.
Azienda Ospedaliera Universitaria Integrata Verona
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingChina
NCT07915011
Investigation of Pharmacokinetics, Safety of HSK31858 in Subjects With Renal Impairment
Haisco Pharmaceutical Group Co., Ltd.
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingChina
NCT07913009
Investigation of Pharmacokinetics, Safety of HSK31858 in Subjects With Hepatic Impairment
Haisco Pharmaceutical Group Co., Ltd.
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase57 sites
RecruitingGermany, France, United Kingdom, Poland, Portugal, Réunion
NCT06487273
Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis
Physio-Assist
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 228 sites
RecruitingUnited States
NCT07450547
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Anagram Therapeutics, Inc.
Registry updated 30 Oct 2026
Registry record: ClinicalTrials.govPhase 48 sites
Not yet recruitingUnited States
NCT07903311
Iron Repletion in Cystic Fibrosis
University of Michigan
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase2 sites
Not yet recruitingUnited States
NCT07414810
Novel Point-of-care Sweat Chloride Testing Device for Monitoring CFTR Function
Emory University
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 260 sites
RecruitingSpain, United Kingdom, Italy, United States
NCT06559150
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
Registry updated 27 Oct 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingIndia
NCT06160713
Compare Oral Itraconazole and Standard Care Versus Standard Care Alone in Patients With Non-cystic Fibrosis Related Bronchiectasis With Chronic Aspergillus Infection in Reducing Bronchiectasis Exacerbations
Post Graduate Institute of Medical Education and Research, Chandigarh
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.govPhase 288 sites
RecruitingAustralia, Belgium, Germany, Denmark, Spain, France
NCT07048262
Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis (NCFB)
CSL Behring
Registry updated 19 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT07283770
Evaluation of VX-581 in Healthy Participants and in Participants With Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
Registry updated 19 Oct 2026
Registry record: ClinicalTrials.govPhase 44 sites
RecruitingItaly
NCT07809867
Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis
Istituto Giannina Gaslini
Registry updated 14 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingUnited States
NCT07275905
Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection
Ghady Haidar
Registry updated 8 Oct 2026
Registry record: ClinicalTrials.govPhase 239 sites
RecruitingBulgaria, Spain, United Kingdom, Hungary, Italy, Poland
NCT07559175
A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.
Aimmune Nestlé Health Science US R&D, LLC
Registry updated 1 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingFrance
NCT07851831
Reproducibility of Continuous Glucose Monitoring (CGM) in the Assessment of Glucose Metabolism Disorders in Children With Cystic Fibrosis
Hospices Civils de Lyon
Registry updated 1 Oct 2026
Registry record: ClinicalTrials.govEarly Phase 11 site
RecruitingChina
NCT07485543
Safety and Efficacy of Inhaled BMD003 (CFTR mRNA) in Chinese Cystic Fibrosis Patients Aged ≥12 Years
Peking Union Medical College Hospital
Registry updated 1 Oct 2026
Registry record: ClinicalTrials.govPhase 41 site
RecruitingEgypt
NCT07608328
Azithromycin to Modify Bronchiectasis Exacerbation Risk
Assiut University
Registry updated 24 Sept 2026
Registry record: ClinicalTrials.govPhase 12 sites
RecruitingUnited States
NCT06995651
Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis
Michael R. Rickels, MD, MS
Registry updated 31 Aug 2026
Registry record: ClinicalTrials.govPhase 218 sites
RecruitingFrance
NCT06368804
Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis
Centre Hospitalier Intercommunal Creteil
Registry updated 27 Aug 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingUnited Kingdom
NCT07780344
MRI Parameters as Biomarkers in Cystic Fibrosis (FEMPTO)
University of Nottingham
Registry updated 21 Aug 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingEgypt
NCT07722364
HFCWO in Children With Non-CF Bronchiectasis
Sphinx university
Registry updated 28 Jul 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingPakistan
NCT07729787
Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis
Riphah International University
Registry updated 28 Jul 2026
Registry record: ClinicalTrials.govPhase 11 site
Not yet recruitingChina
NCT07696091
Study on Drug Interactions Affecting the Pharmacokinetics of RSS0343 Tablet
Reistone Biopharma Company Limited
Registry updated 10 Jul 2026
Registry record: ClinicalTrials.govPhase 22 sites
Not yet recruitingUnited States
NCT07688070
Verapamil Effect in Cystic Fibrosis-related Dysglycemia
Rhode Island Hospital
Registry updated 9 Jul 2026
Registry record: ClinicalTrials.govPhase 460 sites
RecruitingCanada, United States
NCT05548283
Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study
Chris Goss
Registry updated 8 Jul 2026
Registry record: ClinicalTrials.govPhase 220 sites
RecruitingUnited States
NCT05248230
4D-710 in Adult Patients With Cystic Fibrosis
4D Molecular Therapeutics
Registry updated 6 Jul 2026
Registry record: ClinicalTrials.govPhase 1/21 site
RecruitingJordan
NCT02641769
Intra-Testicular Transplantation of Autologous Stem Cells for Treatment of Non-Obstructive Azoospermia Male Infertility.
Stem Cells Arabia
Registry updated 1 Jul 2026
Registry record: ClinicalTrials.govPhase 43 sites
RecruitingUnited States
NCT07148739
Ensuring Access to Optimal Therapy in CF: The ENACT Study
Arkansas Children's Hospital Research Institute
Registry updated 2 Jun 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- United States83 open trials
- France29 open trials
- United Kingdom15 open trials
- Italy13 open trials
- Germany12 open trials
- Spain11 open trials
- Canada11 open trials
- China10 open trials
- Belgium10 open trials
- Poland8 open trials
- Egypt7 open trials
- Netherlands6 open trials
- Czechia5 open trials
- Denmark5 open trials
- Greece4 open trials
- Pakistan4 open trials
- Sweden4 open trials
- Portugal3 open trials
- Australia3 open trials
- Hungary3 open trials
- Switzerland3 open trials
- Lithuania2 open trials
- Bulgaria2 open trials
- Ireland2 open trials
- New Zealand2 open trials
- Türkiye2 open trials
- Israel1 open trial
- Réunion1 open trial
- India1 open trial
- Japan1 open trial
- Jordan1 open trial
- Cyprus1 open trial
- Slovakia1 open trial
- Austria1 open trial
- Russia1 open trial
- Norway1 open trial
- Hong Kong1 open trial
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Children's Health Queensland Hospital and Health Service
Brisbane, Australia
11 trials · 15 publications · ROR
Cincinnati Children's Hospital Medical Center
Cincinnati, United States
18 trials · 58 publications · ROR
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy
17 trials · 36 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
Status changed: Running, not recruiting → Completed
NCT04391322 · No phase · Canada
Source: ClinicalTrials.govOpened for recruitment
NCT07048262 · Phase 2 · Australia, Belgium, Germany, Denmark, Spain, France
Source: ClinicalTrials.govOpened for recruitment
Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis
NCT06747858 · Phase 2 · Greece, Poland, United States
Source: ClinicalTrials.govStatus changed: Completed → Running, not recruiting
NCT06237335 · Phase 2 · France, United Kingdom, Netherlands, New Zealand, United States
Source: ClinicalTrials.govPhase changed: Phase 1/2 → Phase 2
NCT06237335 · Phase 2 · France, United Kingdom, Netherlands, New Zealand, United States
Source: ClinicalTrials.govStatus changed: Recruiting → By invitation only
NCT05844449 · Phase 3 · Australia, Belgium, Canada, Switzerland, Germany, Denmark
Source: ClinicalTrials.govClosed for recruitment
NCT05422222 · Phase 3 · Australia, Belgium, Canada, Switzerland, Germany, Denmark
Source: ClinicalTrials.govClosed for recruitment
Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis
NCT06747858 · Phase 2 · Greece, Poland, United States
Source: ClinicalTrials.govOpened for recruitment
NCT05422222 · Phase 3 · Australia, Belgium, Canada, Switzerland, Germany, Denmark
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
NCT07048262 · Phase 2 · Australia, Belgium, Germany, Denmark, Spain, France
Source: ClinicalTrials.govNew in the registry
Investigation of Pharmacokinetics, Safety of HSK31858 in Subjects With Renal Impairment
NCT07915011 · Phase 1 · China
Source: ClinicalTrials.gov
New reviews, guidelines and randomised trials in PubMed
Systematic review
Frontiers in digital health · PubMed
Meta-analysis
Mucus Plugging Across Multiple Chronic Respiratory Diseases: A Systematic Review and Meta-analysis.
Lung · PubMed
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
No phaseEnded 8 Oct 2026
Completed50 participants
NCT07895108
Assessment of Static and Dynamic Inspiratory Muscle Strength and Cardiorespiratory Fitness in Adults With Cystic Fibrosis
No phaseEnded 30 Sept 2026
Phase 1/2Ended 9 Sept 2026
Completed26 participants
NCT05668741
A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)
No phaseEnded 31 Aug 2026
Completed35 participants
NCT07841353
Impact of Trikafta on P2X7R and Clinical Outcomes in Cystic Fibrosis
Phase 1Ended 18 Aug 2026
Stopped early17 participants
NCT06603246
A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
Reason given: Sponsor's Decision
Phase 2Ended 28 Jul 2026
Phase 1Ended 10 Jul 2026
Completed165 participants
NCT06154447
Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis
No phaseEnded 30 Jun 2026
Completed35 participants
NCT04391322
Assessment of CFTR-Modulator Treatment in Cystic Fibrosis Lung Disease Using Novel Structural and Functional MRI
No phaseEnded 30 Jun 2026
Phase 2Ended 25 Jun 2026
Completed15 participants
NCT07108153
Proof-of-concept Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of SION-719 When Added to Trikafta
Phase 1/2Ended 22 Jun 2026
Completed71 participants
NCT06016088
A Double-Blind, Active-Controlled, Multiple-Ascending Dose Study of Aerosolized RSP-1502 in Subjects With CF and Chronic PA Lung Infection
No phaseEnded 29 May 2026
No phaseEnded 12 May 2026
Completed100 participants
NCT07135869
Muscle Fatigue in People With Cystic Fibrosis: Insight From a Mobile App
Phase 4Ended 1 May 2026
Phase 1/2Ended 20 Apr 2026
Completed40 participants
2023-508706-23-00
Nebulised RESP30X Nitric Oxide Formulations in NCFB Patients with Pseudomonas Aeruginosa (Pa) (NOPA)
Early Phase 1Ended 31 Mar 2026
No phaseEnded 19 Feb 2026
Completed22 participants
NCT06188988
Viral Infections and Airway Microbiome in Young Children With Cystic Fibrosis
No phaseEnded 4 Feb 2026
Completed114 participants
NCT01533636
CF And Effects of Drugs Mixed Ex Vivo With Sputum for Mucolytic Treatment
Phase 1/2Ended 3 Feb 2026
Completed12 participants
2023-503281-23-00
A study to test how well BI 3720931 is tolerated and whether it improves lung function in people with cystic fibrosis (LenticlairTM 1)
Phase 2Ended 2 Feb 2026
Show more
No phaseEnded 1 Feb 2026
Completed10 participants
NCT04687475
Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis
Phase 2Ended 31 Jan 2026
No phaseEnded 30 Jan 2026
Stopped early79 participants
NCT00001223
Diagnosis and Treatment of Patients With Cystic Fibrosis
Reason given: PI left NIH
Phase 3Ended 29 Jan 2026
Completed71 participants
NCT05153317
Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older
Phase 3Ended 28 Jan 2026
Completed315 participants
NCT04961528
AcTIVE - ACid tranexamic or Terlipressin for Initial emergency treatment of mild to seVere hEmoptysis: a randomized Trial
Phase 4Ended 21 Jan 2026
No phaseEnded 8 Jan 2026
Completed30 participants
NCT06700889
Investigating the Relationship Between Glycemia and Sleep in Adults With Cystic Fibrosis-Related Diabetes
No phaseEnded 31 Dec 2025
Completed9 participants
NCT04680403
Video Telehealth Exercise Training in Cystic Fibrosis
- Pilot and Feasibility Study of an Individualized Telehealth Exercise Program for People with Cystic Fibrosis. · Journal of functional morphology and kinesiology, 2026
No phaseEnded 31 Dec 2025
Withdrawn before start0 participants
NCT02605538
Hepatitis B in Cystic Fibrosis and Latent Tuberculosis Respectively
Reason given: Time and resource deficiency at the Stockholm CF Center.
No phaseEnded Dec 2025
Withdrawn before start0 participants
NCT03655249
Effects of AD on VI in Patients With CF
Reason given: No recruitement, no grant to support this study
No phaseEnded 29 Dec 2025
Phase 4Ended 23 Dec 2025
No phaseEnded 15 Dec 2025
No phaseEnded 10 Dec 2025
Completed3 participants
NCT04075864
Feasibility of a New Model for Exercise Prescription in Cystic Fibrosis
No phaseEnded 8 Dec 2025
Phase 2Ended 8 Dec 2025
Completed40 participants
2024-519856-94-00
Phase 2b Randomized, Double-Blind Study with Phage for CF Subjects with Pseudomonas Lung Infection
No phaseEnded 27 Nov 2025
Completed79 participants
NCT06506773
Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF)
Phase 1/2Ended 14 Nov 2025
Completed43 participants
NCT06159725
A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis
Phase 2Ended 14 Nov 2025
Completed50 participants
2023-504092-25-00
A Two-Part Study to Assess the Effectiveness, Safety, and Blood Levels of Repeat Doses of Inhaled ETD001 in People with Cystic Fibrosis
Phase 2Ended 14 Nov 2025
No phaseEnded 1 Nov 2025
Completed104 participants
NCT07304362
The School-Age Children With Cystic Fibrosis and Their Parents on Health Literacy
No phaseEnded 15 Oct 2025
Completed70 participants
NCT07540936
Effects of an Online Yoga Program on Exercise Capacity and Quality of Life in Bronchiectasis Patients
No phaseEnded 30 Sept 2025
Completed36 participants
NCT05850351
Virtual Reality Based Tele-Exercises on Exercise Capacity in Cystic Fibrosis
Phase 2/3Ended Sept 2025
Withdrawn before start0 participants
NCT05408910
Rifaximin for Treatment of Bloating in Children and Adults With Cystic Fibrosis
Reason given: new drug formulation by the manufacturer
No phaseEnded 24 Sept 2025
Completed70 participants
NCT06147778
Performances and Safety of MuCopilot, a Digital Tool for the Unsupervised Objective Assessment of Cystic Fibrosis
No phaseEnded 17 Sept 2025
Phase 3Ended 4 Sept 2025
Completed67 participants
NCT05882357
Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age
Phase 4Ended 1 Sept 2025
Completed13 participants
NCT04533646
Comparison of Meal-Time Dosing of Insulin in Cystic Fibrosis Related Diabetes
No phaseEnded 30 Aug 2025
Stopped early23 participants
NCT06399094
Frequency-time Analysis of Pathological Lung Sounds: Detection and Quantification of Pathological Sounds in Patients With Cystic Fibrosis, Pulmonary Fibrosis or COPD (Chronic Obstructive Pulmonary Disease)
Reason given: Recruitment issue
No phaseEnded 15 Aug 2025
Phase 1Ended 13 Aug 2025
No phaseEnded 31 Jul 2025
No phaseEnded 31 Jul 2025
Completed74 participants
NCT02128711
Mapping Chemical and Microbiological Heterogeneity Throughout Explanted Cystic Fibrosis Lung Specimens
No phaseEnded 31 Jul 2025
Completed8 participants
NCT03771313
Pharmacokinetic and Pharmacodynamic Analysis of Ceftaroline in Children and Adolescents With Cystic Fibrosis
No phaseEnded 30 Jul 2025
Completed28 participants
NCT06280066
An Intervention-Based Approach to Strengthen the Psychological Health of Children With Cystic Fibrosis and Their Mothers
Phase 1/2Ended 16 Jul 2025
No phaseEnded 30 Jun 2025
Completed643 participants
NCT04923880
Pragmatic Implementation Trial of a CF Primary Palliative Care Intervention
No phaseEnded 30 Jun 2025
Completed21 participants
NCT06645782
Group Cognitive Behavioural Therapy for Adults With Cystic Fibrosis
Phase 2Ended 26 Jun 2025
Completed41 participants
NCT06468527
Clinical Trial to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/Nesolicaftor in Adults With CF
No phaseEnded 2 Jun 2025
Not medical advice. fetched 11 Nov 2026