Thyroid cancer: trials for referral
266 open trials in the registries we read. Each row links to its registry record.
Registry data only. Frontlight does not judge whether a patient can take part: the trial team decides.
Where the open trials are
Type a city to sort by distance. The distance is worked out in your browser; the city is not sent anywhere.
266 trials shown
Phase 1/21 site
Not yet recruitingUnited States
NCT06991738
177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT01005654
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
National Cancer Institute (NCI)
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingChina
NCT06359847
Study of ST-1898 in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer
Beijing Scitech-Mq Pharmaceuticals Limited
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT05229341
Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules
City of Hope Medical Center
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT03160274
Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions
The University of Texas Health Science Center at San Antonio
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase2 sites
RecruitingUnited States
NCT01247597
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
National Cancer Institute (NCI)
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 25 sites
RecruitingUnited States
NCT06959511
Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery
M.D. Anderson Cancer Center
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT01109420
Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT04927416
The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry updated 5 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT02609685
Active Surveillance of Papillary Thyroid Microcarcinoma
Cedars-Sinai Medical Center
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govNo phase17 sites
RecruitingUnited States
NCT05366881
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Adela, Inc
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingChina
NCT07914764
68Ga-labeled Cholecystokinin Receptor (CCK2R) Targeted Molecular Probes in Early Tumor Diagnosis
Nanjing First Hospital, Nanjing Medical University
Registry updated 4 Nov 2026
Registry record: ClinicalTrials.govPhase 31 site
RecruitingUnited States
NCT05999630
Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer
Vanderbilt University Medical Center
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingItaly
NCT05766098
Definition of Mutational Profile of Papillary Thyroid Tumors by Mass-ARRAY
Istituto Auxologico Italiano
Registry updated 3 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
By invitation onlyDenmark
NCT07909603
Head and Neck Cancer Strategies
Aarhus University Hospital
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruiting
NCT07907432
Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid Cancer
Marmara University
Registry updated 2 Nov 2026
Registry record: ClinicalTrials.govPhase 21 site
RecruitingUnited States
NCT03841617
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT00001160
Studies on Tumors of the Thyroid
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Registry updated 29 Oct 2026
Registry record: ClinicalTrials.govPhase 10 sites
Not yet recruiting
NCT07252661
Study of ACC-1898 in Adult Participants With Advanced Solid Tumors
AccSalus Biosciences, Inc.
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 11 site
RecruitingNetherlands
NCT07485569
Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial
Radboud University Medical Center
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govPhase 34 sites
By invitation onlyUnited States
NCT07620574
Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study
Exelixis
Registry updated 28 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingUnited States
NCT03382158
International PPB/DICER1 Registry
Children's Hospitals and Clinics of Minnesota
Registry updated 26 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
RecruitingFrance
NCT03410394
Registry of Endocrine Tumors (Thyroid, Parathyroid, Adrenal, Endocrine Pancreas, Endocrine Digestive Tube)
Central Hospital, Nancy, France
Registry updated 22 Oct 2026
Registry record: ClinicalTrials.govPhase 21 site
Not yet recruitingUnited States
NCT07886905
Pulsed Stereotactic Ablative Radiotherapy (PULSAR) With Systematic Therapy for Thyroid Cancer
Washington University School of Medicine
Pre-treatment window Registry sentence: “Prior systemic therapy for thyroid cancer.”
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.govPhase 32 sites
RecruitingPoland
NCT05468554
Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer
Medical University of Bialystok
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.govPhase 26 sites
RecruitingUnited States
NCT05783323
Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer
Children's Hospital of Philadelphia
Pre-treatment window Registry sentence: “No prior systemic therapy for thyroid cancer, including tropomyosin receptor kinase (TRK) inhibitors.”
Registry updated 21 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingUnited States
NCT07612293
STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection
Jonsson Comprehensive Cancer Center
Registry updated 19 Oct 2026
Registry record: ClinicalTrials.govPhase 27 sites
RecruitingUnited States
NCT06007924
A Study of Avutometinib and Defactinib in People With Thyroid Cancer
Memorial Sloan Kettering Cancer Center
Registry updated 15 Oct 2026
Registry record: ClinicalTrials.govPhase 1/26 sites
RecruitingUnited States
NCT06239194
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
ModeX Therapeutics, An OPKO Health Company
Registry updated 15 Oct 2026
Registry record: ClinicalTrials.govNo phase1 site
Not yet recruitingUnited States
NCT07529080
Personalized Cancer Support (Thrive Track) to Manage the Emotional Needs of Young Adults With Thyroid, Melanoma and Testicular Cancer, PerCS-YA Trial
University of Michigan Rogel Cancer Center
Registry updated 15 Oct 2026
Registry record: ClinicalTrials.gov
The same sites as a list
- China82 open trials
- United States76 open trials
- Italy22 open trials
- France11 open trials
- Spain9 open trials
- United Kingdom9 open trials
- Netherlands8 open trials
- Canada8 open trials
- South Korea7 open trials
- Denmark6 open trials
- Australia5 open trials
- Japan5 open trials
- Egypt4 open trials
- Germany3 open trials
- Norway3 open trials
- Singapore3 open trials
- Poland2 open trials
- Hong Kong SAR China2 open trials
- Mexico2 open trials
- Sweden2 open trials
- Hungary2 open trials
- Belgium2 open trials
- Russia2 open trials
- Taiwan2 open trials
- India1 open trials
- Malaysia1 open trials
- Switzerland1 open trials
- Croatia1 open trials
- Romania1 open trials
- Brazil1 open trials
- Colombia1 open trials
Who treats this
Institutions with trials or publications in this disease (OpenAlex, registries). Institutions only, no people.
Cancer Hospital of Chinese Academy of Medical Sciences
Beijing, China
0 trials · 39 publications · ROR
Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, China
0 trials · 149 publications · ROR
Consejo Nacional de Investigaciones Científicas y Técnicas
Buenos Aires, Argentina
0 trials · 24 publications · ROR
King Faisal Specialist Hospital & Research Centre
Riyadh, Saudi Arabia
0 trials · 31 publications · ROR
The First Affiliated Hospital, Sun Yat-sen University
Guangzhou, China
0 trials · 35 publications · ROR
The Maria Sklodowska-Curie National Research Institute of Oncology
Warsaw, Poland
0 trials · 34 publications · ROR
The University of Texas MD Anderson Cancer Center
Houston, United States
4 trials · 167 publications · ROR
The University of Texas Southwestern Medical Center
Dallas, United States
0 trials · 37 publications · ROR
Tianjin Medical University Cancer Institute and Hospital
Tianjin, China
2 trials · 74 publications · ROR
University of Electronic Science and Technology of China
Chengdu, China
0 trials · 34 publications · ROR
University of North Carolina at Chapel Hill
Chapel Hill, United States
1 trials · 40 publications · ROR
V.P. Komisarenko Institute of Endocrinology and Metabolism
Kyiv, Ukraine
0 trials · 33 publications · ROR
What changed in the last 7 days
Registry facts, one per line, newest first.
Opened for recruitment
Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial
NCT07485569 · Phase 1 · Netherlands
Source: ClinicalTrials.govOpened for recruitment
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
NCT07006727 · Phase 1 · Canada, Germany, Spain, France, Italy, Japan
Source: ClinicalTrials.govPhase changed: Phase 1 → Early Phase 1
[177Lu]Lu-AKIR001 First-in-human Study
NCT06639191 · Early Phase 1 · Sweden
Source: ClinicalTrials.govPhase changed: Phase 1/2 → Phase 1
NCT05668585 · Phase 1 · Germany, Spain, France, United Kingdom, Italy, United States
Source: ClinicalTrials.govPhase changed: Phase 1/2 → Phase 2
NCT03175224 · Phase 2 · Australia, Canada, Spain, France, United Kingdom, Hungary
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
Drug Repurposing in Thyroid Carcinoma: a Feasibility Trial
NCT07485569 · Phase 1 · Netherlands
Source: ClinicalTrials.govStatus changed: Recruiting → Not yet recruiting
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors
NCT07006727 · Phase 1 · Canada, Germany, Spain, France, Italy, Japan
Source: ClinicalTrials.govNew in the registry
68Ga-labeled Cholecystokinin Receptor (CCK2R) Targeted Molecular Probes in Early Tumor Diagnosis
NCT07914764 · No phase · China
Source: ClinicalTrials.gov
New reviews, guidelines and randomised trials in PubMed
Systematic review
Frontiers in endocrinology · PubMed
Systematic review
A systematic review on the possible role of microRNA-155 in cancer treatment.
Frontiers in pharmacology · PubMed
Randomised trial
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · PubMed
Results card
Trials that finished or stopped in the last 3 years, with the reason the registry gives and linked publications.
Phase 1Ended 30 Oct 2026
Completed18 participants
NCT03435952
Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT
No phaseEnded 4 Aug 2026
Completed874 participants
NCT07255482
Mortality Benefit of Ultrasound for Thyroid Nodules Identified With PET Imaging: Non-Inferiority Emulated Target Trial
No phaseEnded 31 Jul 2026
Phase 1Ended 3 Jun 2026
Completed70 participants
NCT05241834
A Study of LOXO-260 in Cancer Patients With a Change in a Particular Gene (RET) That Has Not Responded to Treatment
Phase 1/2Ended 2 Jun 2026
Completed98 participants
NCT05864144
A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors
No phaseEnded 31 May 2026
Completed98 participants
NCT07652450
Incidental Thyroid Cancer in Cases With Inflammatory Thyroid Lesion
Phase 2Ended 27 May 2026
No phaseEnded 15 May 2026
Completed32 participants
NCT07623005
Progressive Muscle Relaxation for Pain and Quality of Life in Thyroid Cancer
No phaseEnded 22 Apr 2026
Completed250 participants
NCT05078853
Thyroglobulin Point of Care Assay for Rapid Detection of Metastatic Differentiated Thyroid Carcinoma
No phaseEnded 4 Apr 2026
No phaseEnded 15 Mar 2026
Phase 2Ended 12 Mar 2026
Completed100 participants
NCT07911891
Oral Mecobalamin for TKI-Associated Hand-Foot Syndrome in Advanced Thyroid Cancer
No phaseEnded 23 Feb 2026
Completed124 participants
NCT07752277
Quantitative Pharmacology-Based Dose Adjustment Protocol in Postoperative Thyroid Cancer Patients
Phase 3Ended 31 Jan 2026
Completed390 participants
NCT04964284
rhTSH for Radioactive Iodine Remnant Ablation in Participants With Differentiated Thyroid Cancer (DTC)
No phaseEnded 30 Jan 2026
Phase 2Ended 15 Jan 2026
Completed40 participants
NCT03244956
Efficacy of MEK (Trametinib) and BRAFV600E (Dabrafenib) Inhibitors With Radioactive Iodine (RAI) for the Treatment of Refractory Metastatic Differentiated Thyroid Cancer
- Lesional dosimetry in 131I refractory metastatic differentiated thyroid cancer with BRAFp.V600E or RAS mutation treated with trametinib +/- dabrafenib followed by radioactive iodine. · Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), 2026
- MERAIODE: A Phase II Redifferentiation Trial with Trametinib and 131I in Metastatic Radioactive Iodine Refractory RAS Mutated Differentiated Thyroid Cancer. · Thyroid : official journal of the American Thyroid Association, 2023
No phaseEnded 31 Dec 2025
Completed27 participants
NCT07506161
Radiofrequency Ablation Treatment of Low-Risk Papillary Thyroid Carcinomas
No phaseEnded 31 Dec 2025
Completed549 participants
NCT04593277
Interactive Survivorship Program for the Improvement of Healthcare Resources in Adolescent and Young Adult Cancer Survivors, INSPIRE-AYA Study
No phaseEnded 22 Dec 2025
No phaseEnded 20 Dec 2025
Completed50 participants
NCT06073223
Intervention to Decrease Overtreatment of Patients With Low-risk Thyroid Cancer
Phase 1/2Ended 18 Dec 2025
Completed40 participants
NCT05708950
A Clinical Trial of KVA12123 [TBS-2025] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)
No phaseEnded 1 Dec 2025
Phase 2Ended 30 Nov 2025
Completed41 participants
NCT05660954
Cabozantinib In Advanced Radioactive-Iodine Refractory Differentiated Thyroid Cancer.
Phase 1/2Ended 13 Nov 2025
Completed33 participants
NCT05745363
Clinical Study of AL2846 Capsule in the Treatment of Differentiated Thyroid Cancer
No phaseEnded 10 Nov 2025
Completed58 participants
NCT07274670
Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid Surgery
Phase 1Ended 5 Nov 2025
No phaseEnded 3 Nov 2025
Completed49 participants
NCT07298187
The Effect of Head Position on the Optik Nerve Sheath Diameter in Patients During Thyroid Surgery
No phaseEnded 15 Oct 2025
No phaseEnded 5 Oct 2025
Completed63 participants
NCT06171945
Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors
Phase 1Ended 2 Oct 2025
No phaseEnded 29 Sept 2025
Completed603 participants
NCT04000880
Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health
Phase 2Ended 29 Sept 2025
Completed215 participants
NCT02576431
A Study to Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors
- Cancer control after pausing treatment with larotrectinib in responding children with sarcoma and a TRK fusion: a plain language summary. · Future oncology (London, England), 2026
No phaseEnded 19 Sept 2025
Completed66 participants
NCT07659717
Frozen Section-Guided Selective Ipsilateral Central Neck Dissection in Bethesda V-VI Thyroid Nodules
Phase 4Ended 4 Sept 2025
Completed50 participants
NCT03573960
A Study to Evaluate the Safety and Efficacy of Lenvatinib in Participants With Refractory Differentiated Thyroid Cancer
Phase 1Ended 11 Aug 2025
Completed45 participants
NCT05851560
Prospective Comparison of the Effect on Antiadhesive Barriers During Thyroid Surgery
No phaseEnded 8 Aug 2025
Completed33 participants
NCT06582849
Enhanced Assistance During Radiotherapy for Unmet Essential Needs
No phaseEnded 5 Jul 2025
Completed80 participants
NCT05265819
Effect of Exergaming Exercises and Mediterranean Diet on Thyroid Cancer Patients Following Total Thyroidectomy
No phaseEnded 6 Jun 2025
Completed82 participants
NCT04481893
Interest of the Virtual Reality Headset in the Management of Perioperative Stress in Patients Candidates for Total Thyroidectomy
No phaseEnded 31 May 2025
Completed143 participants
NCT07575243
Thyroidectomy-specific Enhanced Recovery After Surgery (ERAS) Protocol
No phaseEnded 31 May 2025
Completed430 participants
NCT06958601
Safety and Efficacy of Transoral Robotic Thyroidectomy Versus Traditional Open Thyroidectomy for Thyroid Cancer
No phaseEnded 31 May 2025
Completed100 participants
NCT05752669
Oxidative Stress and Mitochondrial TERT in Papillary Thyroid Cancer.
Phase 2/3Ended 7 May 2025
No phaseEnded 1 May 2025
Completed100 participants
NCT07911761
Prophylactic Central Neck Dissection for Papillary Thyroid Carcinoma
No phaseEnded 31 Mar 2025
Completed138 participants
NCT05789667
Gender-based Impact on Safety and Efficacy of Lenvatinib in Patients With Differentiated Thyroid Cancer
Phase 1Ended 31 Mar 2025
Completed11 participants
NCT05275946
Targeted Alpha Therapy Using Astatine (At-211) Against Differentiated Thyroid Cancer
Phase 1Ended 27 Mar 2025
Completed12 participants
NCT05410821
Evaluation of 177Lu-DOTA-EB-FAPI in Patients With Metastatic Radioactive Iodine Refractory Thyroid Cancer
Phase 3Ended 13 Mar 2025
Phase 1Ended 10 Mar 2025
No phaseEnded 9 Feb 2025
Phase 1Ended 6 Feb 2025
Completed19 participants
NCT06048367
Carbon Nanoparticle-Loaded Iron [CNSI-Fe(II)] in the Treatment of Advanced Solid Tumor
- Carbon nanoparticle-Fe (II) complex for ferroptosis therapy in refractory solid tumors: a phase I trial. · Signal transduction and targeted therapy, 2026
- First-in-human evidence of multidrug resistance reversal in solid tumors: a cohort analysis of carbon nanoparticles‑Fe(II) complex trials. · BMC cancer, 2026
No phaseEnded 20 Jan 2025
Completed21 participants
NCT06793579
Lateral Approach for Mediastinal Lymph Node Dissection in Thyroid Cancer
Phase 2Ended 5 Jan 2025
Completed9 participants
NCT04552769
Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer
Phase 4Ended 1 Jan 2025
Completed600 participants
NCT06697782
Aprepitant and Ondansetron Monotherapy or Combination for Postoperative Nausea and Vomiting in Thyroid Cancer
No phaseEnded 1 Jan 2025
No phaseEnded 31 Dec 2024
Completed181 participants
NCT06791174
Tumor Microenvironmental Collagen Signature to Predict Thyroid Cancer Superior Mediastinal Lymph Node Metastasis
No phaseEnded 31 Dec 2024
Completed80 participants
NCT05579782
Assessing Benefits of NIRAF Detection for Identifying Parathyroid Glands During Total Thyroidectomy
No phaseEnded 31 Dec 2024
No phaseEnded 31 Dec 2024
Completed250 participants
NCT05025046
NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules
No phaseEnded 31 Dec 2024
Completed8 participants
NCT05534594
Evaluation of the 18F-PSMA Positron Emission Tomography (PET)/CT in Patients With Medullary Thyroid Cancer
Phase 2Ended 31 Dec 2024
Completed103 participants
NCT04521348
Multiple Target Kinase Inhibitor and Anti-Programmed Death-1 Antibody in Patients With Advanced Thyroid Cancer
Not medical advice. fetched 6 Nov 2026