Hospital for Sick Children

Running trials

• Not yet recruiting

  A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to Epidiolex

  NCT06924827· Phase 4· Source

• Not yet recruiting

  COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

  NCT07281027· Phase 3· Source

• Recruiting

  Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype

  NCT07282210· Phase 2· Source

• Enrolling by invitation

  3D Ultrasound in Hemophilic Ankles

  NCT07452575· Source

• Recruiting

  MedlyPeds Feasibility Study

  NCT07556185· Source

• Recruiting

  A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

  NCT07192952· Phase 3· Source

• Not yet recruiting

  Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma

  NCT07518654· Phase 1· Source

• Recruiting

  A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis

  NCT07158242· Phase 3· Source

• Not yet recruiting

  MRI Assessment of Lung Airways in Cystic Fibrosis: Evaluate MRI's Ability to Detect Changes in Airway Structure .

  NCT07454681· Source

• Not yet recruiting

  Pain Caregiver Resource (PainCaRe)

  NCT06651190· Source

• Recruiting

  A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients

  NCT07549321· Phase 2/3· Source

• Recruiting

  A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

  NCT07287982· Phase 2· Source

• Active, not recruiting

  A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

  NCT07107945· Phase 3· Source

• Recruiting

  A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

  NCT06979453· Phase 3· Source

• Not yet recruiting

  Deep Brain Stimulation vs. Vagus Nerve Stimulation for Epileptic Spasms

  NCT07010276· Source

• Recruiting

  A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

  NCT07188805· Phase 3· Source

• Recruiting

  The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services

  NCT06455384· Source

• Recruiting

  A Study of SGT-003 Gene Therapy in Ambulant Males With Duchenne Muscular Dystrophy (IMPACT DUCHENNE)

  NCT07160634· Phase 3· Source

• Recruiting

  Magnesium Trial in Acute Asthma in Emergency Department

  NCT06785272· Phase 3· Source

• Recruiting

  Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

  NCT06942039· Early phase 1· Source

• Not yet recruiting

  The iPeer2Peer Mentorship Program for Young Adults With Heart Disease

  NCT07119216· Source

• Recruiting

  Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

  NCT06333899· Early phase 1· Source

• Not yet recruiting

  Three Times Weekly Symptom Screening for Children With Cancer

  NCT04275102· Source

• Recruiting

  CANnabinoids in Pediatric ONCology

  NCT05754840· Phase 1/2· Source

• Active, not recruiting

  A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

  NCT07015983· Phase 2· Source

• Recruiting

  ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

  NCT06838676· Phase 2· Source

• Active, not recruiting

  Timely Ordering of Pharmacogenetic Testing

  NCT06902688· Source

• Recruiting

  A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

  NCT06124157· Phase 2· Source

• Recruiting

  A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

  NCT06941272· Phase 1/2· Source

• Recruiting

  A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

  NCT06401330· Phase 3· Source

• Recruiting

  Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

  NCT06647953· Phase 3· Source

• Active, not recruiting

  Vomiting Prevention in Children With Cancer

  NCT06886451· Source

• Recruiting

  Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

  NCT06376162· Phase 1· Source

• Enrolling by invitation

  Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

  NCT06823115· Source

• Recruiting

  WeRoaM: Wearable Remote Monitoring in Heart Failure

  NCT06969560· Source

• Enrolling by invitation

  A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)

  NCT06908226· Phase 3· Source

• Recruiting

  Study of Olutasidenib and Temozolomide in HGG

  NCT06161974· Phase 2· Source

• Recruiting

  A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

  NCT06609226· Phase 3· Source

• Recruiting

  CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

  NCT06208735· Phase 1· Source

• Active, not recruiting

  Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene

  NCT06627179· Phase 2· Source

• Recruiting

  A Pilot Study Investigating Upfront Adaptive Immunotherapy Approach in Children, Adolescent and Young Adult (CAYA) Patients With Replication-Repair Deficient (RRD) High-Grade Gliomas (HGG)

  NCT06519682· Source

• Recruiting

  Avapritinib Rollover Study

  NCT06748001· Phase 4· Source

• Active, not recruiting

  Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older

  NCT06460506· Phase 3· Source

• Active, not recruiting

  A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathies (DEE)

  NCT06719141· Phase 3· Source

• Recruiting

  A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

  NCT06368817· Phase 2· Source

• Active, not recruiting

  A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

  NCT06660394· Phase 3· Source

• Active, not recruiting

  STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss

  NCT06571383· Phase 4· Source

• Recruiting

  Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

  NCT06232304· Source

• Recruiting

  Deep Brain Stimulation for Severe Self-Injurious Behaviour in Children

  NCT06529380· Source

• Recruiting

  Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

  NCT05843253· Phase 2· Source

Recruiting at the same time

How many trials recruit for the same indication here at once. A count, not a rating.

• Childhood cancers49 recruiting
• Heart failure8 recruiting
• Neuroblastoma8 recruiting
• Acute lymphoblastic leukaemia7 recruiting
• Epilepsy7 recruiting
• High blood pressure5 recruiting
• Sarcoma5 recruiting
• Acute myeloid leukemia4 recruiting
• Crohn's disease4 recruiting
• Glioblastoma4 recruiting
• Psoriasis4 recruiting
• Sickle cell disease4 recruiting
• Chronic kidney disease3 recruiting
• Cystic fibrosis3 recruiting
• Haemophilia3 recruiting
• Ulcerative colitis3 recruiting
• Asthma2 recruiting
• Diffuse large B-cell lymphoma2 recruiting
• Duchenne muscular dystrophy2 recruiting
• Kidney cancer2 recruiting
• Lupus (SLE)2 recruiting
• Obesity2 recruiting
• Ovarian cancer2 recruiting
• Psoriatic arthritis2 recruiting
• Pulmonary arterial hypertension2 recruiting
• Autism1 recruiting
• Chronic lymphocytic leukaemia1 recruiting
• Friedreich ataxia1 recruiting
• Gastric and esophageal cancer1 recruiting
• Liver and biliary tract cancer1 recruiting
• Mantle cell lymphoma1 recruiting
• Multiple sclerosis1 recruiting
• Myelodysplastic syndromes1 recruiting
• Neuromyelitis optica (NMOSD)1 recruiting
• Pancreatic cancer1 recruiting
• Retinitis pigmentosa1 recruiting
• Rheumatoid arthritis1 recruiting
• Spinal muscular atrophy1 recruiting
• Stroke1 recruiting
• Systemic sclerosis (scleroderma)1 recruiting
• Thalassaemia1 recruiting
• Type 1 diabetes1 recruiting

Researchers

No researcher is linked here yet.

Closed trials

• Completed

  Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF)

  NCT06506773· Source

• Completed

  Canadian CHO-KLAT/H-FIT Study - Quality of Life of, and Burden of Caring for, Persons With Hemophilia

  NCT06191068· Source

• Terminated

  A Study Of PGN-EDO51 In Participants With Duchenne Muscular Dystrophy Amenable To Exon 51-Skipping Treatment

  NCT06079736· Phase 2· Source

• Completed

  A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis

  NCT05784246· Phase 3· Source

• Terminated

  Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

  NCT05934630· Source

• Completed

  A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex

  NCT05864846· Phase 4· Source

• Completed

  Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less Than 24 Months of Age

  NCT05882357· Phase 3· Source

• Recruiting

  A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell Disease

  NCT06198712· Phase 2· Source

• Completed

  Research Study Investigating How Well NDec Works in People With Sickle Cell Disease

  NCT05405114· Phase 2· Source

• Completed

  A Study to Investigate the Safety and Efficacy of RO7204239 in Combination With Risdiplam (RO7034067) in Participants With Spinal Muscular Atrophy

  NCT05115110· Phase 2/3· Source

• Terminated

  Tovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid Tumors

  NCT07121829· Phase 1· Source

• Completed

  A Research Study Looking at Mim8 in Children With Haemophilia A With or Without Inhibitors

  NCT05306418· Phase 3· Source

• Completed

  Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy

  NCT05323734· Phase 3· Source

• Completed

  A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease

  NCT04987489· Phase 2· Source

• Completed

  A Study to Assess Vamorolone in Boys Ages 2 to <4 Years and 7 to <18 Years With Duchenne Muscular Dystrophy (DMD)

  NCT05185622· Phase 2· Source

• Terminated

  A Study of Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

  NCT05163314· Phase 3· Source

• Completed

  A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling

  NCT04773782· Phase 1/2· Source

• Completed

  Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older

  NCT05153317· Phase 3· Source

• Completed

  Keeping in Touch (KiT) With Youth as They Transition to Adult Type 1 Diabetes Care

  NCT05434754· Source

• Completed

  Evaluate Efficacy, Safety and Tolerability, PK and PD of Emapalumab in Children and Adults With MAS in Still's or SLE

  NCT05001737· Phase 3· Source

• Completed

  A Research Study Investigating Mim8 in Adults and Adolescents With Haemophilia A With or Without Inhibitors

  NCT05053139· Phase 3· Source

• Completed

  A Study of Soticlestat as an Add-on Therapy in Children, Teenagers, and Adults With Lennox-Gastaut Syndrome

  NCT04938427· Phase 3· Source

• Completed

  A Study of Soticlestat as an Add-on Therapy in Children and Young Adults With Dravet Syndrome

  NCT04940624· Phase 3· Source

• Completed

  Fitness to Aid the Brain and Cognitive Skills

  NCT05367076· Source

• Withdrawn

  Breastmilk Composition and Microbial Profile in the Growth and Development of Healthy Term-born Infants

  NCT06970535· Source

• Terminated

  Testing the Combination of Two Immunotherapy Drugs (Magrolimab and Dinutuximab) in Patients With Relapsed or Refractory Neuroblastoma or Relapsed Osteosarcoma

  NCT04751383· Phase 1· Source

• Recruiting

  Study of Lunresertib Alone or in Combination With RP-3500 or Zedoresertib (Debio 0123) in Patients With Advanced Solid Tumors

  NCT04855656· Phase 1· Source

• Completed

  Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

  NCT04671433· Phase 3· Source

• Completed

  Assessment of CFTR-Modulator Treatment in Cystic Fibrosis Lung Disease Using Novel Structural and Functional MRI

  NCT04391322· Source

• Terminated

  A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome

  NCT04572243· Phase 3· Source

• Completed

  Telehealth CBT for Adolescents and Young Adults With Childhood-onset Systemic Lupus Erythematosus

  NCT04335643· Source

• Completed

  A Study of Subcutaneous Risankizumab Injection for Pediatric Participants With Moderate to Severe Plaque Psoriasis to Assess Change in Disease Symptoms

  NCT04435600· Phase 3· Source

• Completed

  HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

  NCT04670016· Source

• Completed

  Topotecan Episcleral Plaque for Treatment of Retinoblastoma

  NCT04428879· Phase 1· Source

• Completed

  Study of the Efficacy and Safety PF-06741086 in Adult and Teenage Participants With Severe Hemophilia A or Moderately Severe to Severe Hemophilia B

  NCT03938792· Phase 3· Source

• Recruiting

  Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

  NCT04278404· Source

• Completed

  Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA TC Combination Therapy in Participants With Cystic Fibrosis Who Are 6 Years of Age and Older

  NCT04183790· Phase 3· Source

• Completed

  Hyperpolarized Imaging for New Treatments

  NCT04259970· Phase 4· Source

• Completed

  The Pain Squad+ Smartphone App To Support Real-Time Pain Management for Adolescents With Cancer

  NCT03632343· Source

• Completed

  Study of the Bromodomain (BRD) and Extra-Terminal Domain (BET) Inhibitors BMS-986158 and BMS-986378 in Pediatric Cancer

  NCT03936465· Phase 1· Source

• Completed

  Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine

  NCT03832998· Phase 3· Source

• Completed

  Deep Brain Stimulation in Children With Autism

  NCT03982888· Source

• Completed

  Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

  NCT03709680· Phase 2· Source

• Completed

  A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease

  NCT03745287· Phase 2/3· Source

• Completed

  Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers

  NCT03365687· Phase 3· Source

• Completed

  A Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia

  NCT03655678· Phase 2/3· Source

• Terminated

  A Study of Soticlestat in Adults and Children With Rare Epilepsies

  NCT03635073· Phase 2· Source

• Completed

  Inflammatory Biomarkers of Pediatric Pulmonary Hypertension

  NCT03581695· Source

• Completed

  Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR)

  NCT03349242· Source

• Completed

  Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Cancer

  NCT03223753· Phase 3· Source

Trial sites

• #2002, The Hospital for Sick Children1 trial
• Division of Haematology/Oncology Hospital for Sick Children1 trial
• Hospital for Sick Children119 trials
• Hospital for Sick Children - Hematology2 trials
• Hospital for Sick Children /ID# 1279101 trial
• Hospital for Sick Children /ID# 2261671 trial
• Hospital for Sick Children /ID# 2339861 trial
• Hospital for Sick Children /ID# 2407671 trial
• Hospital for Sick Children /ID# 2509451 trial
• Hospital for Sick Children /ID# 2578791 trial
• Hospital for Sick Children - Pulmonology2 trials
• Hospital for Sick Kids1 trial
• SickKids1 trial
• Sick Kids Hospital1 trial
• SickKids - The Hospital for Sick Children3 trials
• The Hospital for Sick Children131 trials
• The Hospital for Sick Children - Division of Gastroenterology, Hepatology and Nutrition1 trial
• The Hospital for Sick Children (MRD-HCT)1 trial
• The Hospital for Sick Children (Sick Kids)1 trial
• The Hospital for Sick Children (SickKids)16 trials
• The Hospital for Sick Children (SickKids) | Cardiology1 trial
• The Hospital for Sick Children (Site 0500)1 trial
• The Hospital for Sick Children (Site 1225)1 trial
• The Hospital for Sick Children (Site 3225)1 trial
• The Hospital for Sick Children (Toronto SickKids)1 trial
• The Hospital for Sick Kids1 trial
• The Hospital of Sick Children2 trials
• University of Toronto Division of Hematology Oncology/The Hospital for Sick Children1 trial
• University of Toronto, Hospital for Sick Children1 trial

Conditions

Diseases this institution publishes on or runs trials for.

• Childhood cancers83 works · 157 trials
• Epilepsy78 works · 15 trials
• Crohn's disease60 works · 7 trials
• Cystic fibrosis52 works · 13 trials
• Autism49 works · 2 trials
• Asthma46 works · 5 trials
• Multiple sclerosis33 works · 3 trials
• Acute lymphoblastic leukaemia32 works · 25 trials
• Sarcoma29 works · 22 trials
• Glioblastoma26 works · 7 trials
• Lupus (SLE)25 works · 5 trials
• Type 1 diabetes20 works · 4 trials
• Hodgkin lymphoma19 works · 3 trials
• Neuroblastoma16 works · 24 trials
• Sickle cell disease14 works · 10 trials
• Haemophilia11 works · 12 trials
• Duchenne muscular dystrophy9 works · 6 trials
• Familial hypercholesterolaemia6 works · 0 trials
• Retinitis pigmentosa3 works · 8 trials