Depression trials in United States

In United States 272 Also abroad 666

272 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Triage Survey for Psychiatry Research Eligibility
Where
Boston, DeSoto, New York, Philadelphia, The Bronx, Watertown
Age
18 years and over
People
20,000
Run by
Adams Clinical
See details and how to joinNCT05800925
No phaseEnrolling by invitation
Causal Role of Rostromedial Prefrontal Cortex for Positive Savoring in Depression
Where
Tallahassee
Age
18 years to 65 years
People
48
Run by
Florida State University
See details and how to joinNCT07467473
No phaseTaking people
Neural Correlates of Stress and Perceived Control in Adolescent Depression
Where
Belmont
Age
14 years to 18 years
People
80
Run by
Mclean Hospital
See details and how to joinNCT04788524
Phase 2Taking people
Stratified Pharmacological Approaches for Regulating Circuit-Level Effects
Where
Palo Alto
Age
18 years to 65 years
People
60
Run by
Stanford University
See details and how to joinNCT07022405
Phase 2Taking people
Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer
Where
Columbus
Age
18 years and over
People
10
Run by
Alan Davis
See details and how to joinNCT07216404
No phaseTaking people
Mechanisms Of Orbitofrontal Stimulation in Depression
Where
Boston
Age
18 years to 65 years
People
80
Run by
Subha Subramanian
See details and how to joinNCT07230990
Early phase 1Taking people
Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression
Where
Belmont
Age
18 years and over
People
80
Run by
Mclean Hospital
See details and how to joinNCT07560878
Phase 4Taking people
Aβ Dynamics in LLMD
Where
New York, Orangeburg
Age
60 years and over
People
60
Run by
NYU Langone Health
See details and how to joinNCT05004987
Phase 2Taking people
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Where
West Haven
Age
21 years to 65 years
People
30
Run by
Yale University
See details and how to joinNCT05786066
Phase 1Taking people
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response
Where
New Haven
Age
18 years to 60 years
People
50
Run by
Yale University
See details and how to joinNCT05915013
Phase 4Taking people
Establishing Mobile Transcranial Magnetic Stimulation
Where
Charleston
Age
22 years to 80 years
People
30
Run by
Medical University of South Carolina
See details and how to joinNCT06748209
Phase 2Not yet taking people in United States
Study of Psilocybin Under Anesthesia Controlled by EEG
Where
Stanford
Age
25 years to 65 years
People
10
Run by
Stanford University
See details and how to joinNCT07479550
Phase 2Taking people
Mindfulness Engaged Neurostimulation for Depression (MEND II)
Where
San Diego
Age
18 years to 65 years
People
120
Run by
University of California, San Diego
See details and how to joinNCT07512284
No phaseTaking people
RESISTance Exercise for Depression Trial
Where
Ames, Madison
Age
18 years to 65 years
People
200
Run by
University of Wisconsin, Madison
See details and how to joinNCT06110897
No phaseTaking people
Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method
Where
Washington D.C.
Age
18 years to 65 years
People
80
Run by
Georgetown University
See details and how to joinNCT07028216
Phase 2Taking people
Regulation of Affect and Physiology in Depression
Where
Los Angeles
Age
18 years to 27 years
People
252
Run by
University of Southern California
See details and how to joinNCT06345859
Phase 2Not yet taking people in United States
Group PACBT for Depression
Where
Los Angeles
Age
21 years to 60 years
People
30
Run by
University of California, Los Angeles
See details and how to joinNCT07566104
Phase 2Taking people
Ketamine Alcohol (in Treatment-Resistant Depression)
Where
Iowa City
Age
18 years to 55 years
People
60
Run by
Mark Niciu
See details and how to joinNCT02122562
Phase 4Taking people
Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression
Where
Austin
Age
18 years to 65 years
People
50
Run by
University of Texas at Austin
See details and how to joinNCT05892744
No phaseTaking people
Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia
Where
Houston, Providence
Age
22 years to 75 years
People
170 worldwide
Run by
GrayMatters Health Ltd.
See details and how to joinNCT06982820
No phaseTaking people
Mindfulness-Based fMRI Neurofeedback for Depression
Where
Boston, New York
Age
13 years to 18 years
People
90
Run by
Columbia University
See details and how to joinNCT05617495
No phaseTaking people
Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) Study
Where
Rochester
Age
18 years and over
People
200
Run by
Mayo Clinic
See details and how to joinNCT06897670
No phaseTaking people
Maintenance rTMS for Depression (Maitr-De)
Where
New York, San Diego
Age
18 years to 80 years
People
75 worldwide
Run by
University of California, San Diego
See details and how to joinNCT06938841
Phase 3Taking people
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
Where
Aurora, Boston, Charleston, Meridian, Savannah
Age
18 years and over
People
1,900 worldwide
Run by
Senseye, Inc.
See details and how to joinNCT07280065
Phase 2Taking people
Neutralizing Interleukin (IL)-6
Where
New York
Age
18 years to 70 years
People
60
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07493317