Depression trials in United States

In United States 272 Also abroad 666

272 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Nebulized Ketamine for the Treatment of Major Depressive Disorder
Where
Brooklyn
Age
18 years to 88 years
People
40
Run by
Theresa Jacob, PhD, MPH
See details and how to joinNCT06752759
Phase 1/2Taking people
Neural Response to Inflammatory Challenge in Major Depressive Disorder
Where
Tulsa
Age
18 years to 65 years
People
180
Run by
Laureate Institute for Brain Research, Inc.
See details and how to joinNCT04751331
Phase 1/2Not yet taking people in United States
A Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients
Where
Los Angeles
Age
21 years to 85 years
People
12
Run by
BioLite, Inc.
See details and how to joinNCT03833206
Phase 2Enrolling by invitation
Bright Light Therapy for Depressed Geriatric Inpatients
Where
Charleston
Age
60 years and over
People
20
Run by
Medical University of South Carolina
See details and how to joinNCT07002554
No phaseTaking people
Brain Stimulation for Severe Depression
Where
Boston, St Louis
Age
21 years to 80 years
People
20
Run by
Inner Cosmos Inc
See details and how to joinNCT05393622
No phaseTaking people
ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1
Where
Laguna Hills, La Jolla
Age
18 years and over
People
5,000
Run by
Salma Health, Inc.
See details and how to joinNCT07528014
No phaseNot yet taking people in United States
Early Brainwave Biomarkers for Personalized Neuromodulation in Treatment-resistant Depression
Where
Stanford
Age
18 years to 65 years
People
80
Run by
Stanford University
See details and how to joinNCT07528157
No phaseTaking people
MicroRNA Correlates of Childhood Maltreatment and Suicidality
Where
Birmingham, Huntsville
Age
18 years to 60 years
People
450
Run by
University of Alabama at Birmingham
See details and how to joinNCT04923685
No phaseTaking people
Brain Changes During Social Reward Psychotherapy for Mid- and Late-Life Suicidality
Where
New York
Age
50 years to 80 years
People
128
Run by
Weill Medical College of Cornell University
See details and how to joinNCT05925322
No phaseTaking people
Nutritional Intervention for College Students With Depression
Where
La Jolla
Age
18 years and over
People
30
Run by
University of California, San Diego
See details and how to joinNCT07490782
No phaseEnrolling by invitation
Spectral TMS (s-TMS)
Where
Los Angeles
Age
18 years to 65 years
People
10
Run by
University of California, Los Angeles
See details and how to joinNCT04040062
No phaseTaking people
Disruptions of Brain Networks and Sleep by Electroconvulsive Therapy
Where
St Louis
Age
21 years to 65 years
People
50
Run by
Washington University School of Medicine
See details and how to joinNCT05905705
No phaseTaking people
Investigating the Neural Mechanisms of Repetitive Brain Stimulation With Invasive and Noninvasive Electrophysiology in Humans
Where
Stanford
Age
18 years to 65 years
People
49
Run by
Stanford University
See details and how to joinNCT05996900
No phaseTaking people
Behavioral Health Collaborative Care Model in an ICU Recovery Clinic
Where
Charleston
Age
18 years and over
People
150
Run by
Medical University of South Carolina
See details and how to joinNCT07372586
No phaseTaking people
Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot
Where
Charleston
Age
18 years and over
People
150
Run by
Medical University of South Carolina
See details and how to joinNCT07390786
No phaseTaking people
Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide Risk
Where
Sacramento
Age
15 years to 25 years
People
25
Run by
University of California, Davis
See details and how to joinNCT07025720
Phase 2Taking people
Imaging Depression in Parkinson's Disease
Where
New Haven
Age
40 years to 80 years
People
120
Run by
Yale University
See details and how to joinNCT06402955
No phaseTaking people
Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services
Where
Athens, Belmont, Boston, Chicago, Dallas, Hartford
Age
18 years to 40 years
People
320
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT06740383
No phaseNot yet taking people in United States
Using Integrated Care and Wearable Technology to Evaluate Outcomes of the Shields & Stripes Program for Veterans and First Responders
Where
Waco
Age
18 years to 70 years
People
80
Run by
Baylor University
See details and how to joinNCT07452900
No phaseTaking people
Amygdala Neurofeedback for Depression - Large Scale Clinical Trial
Where
Pittsburgh
Age
18 years to 55 years
People
200
Run by
Kymberly Young
See details and how to joinNCT05703256
No phaseTaking people
Exercise-priming of CBT for Depression: the CBT+ Trial
Where
Madison
Age
18 years to 65 years
People
100
Run by
University of Wisconsin, Madison
See details and how to joinNCT07221929
No phaseTaking people
University of Iowa Interventional Psychiatry Service Patient Registry
Where
Iowa City
Age
18 years to 99 years
People
1,000
Run by
Mark Niciu
See details and how to joinNCT04480918
No phaseTaking people
Using TMS to Understand Neural Processes of Social Motivation
Where
Auburn
Age
25 years to 50 years
People
40
Run by
Auburn University
See details and how to joinNCT06274112
No phaseTaking people
Ultrasound Neuromodulation of Circuits and Negative Valence Systems in Treatment-Resistant Depression
Where
Tulsa
Age
18 years to 65 years
People
140
Run by
Laureate Institute for Brain Research, Inc.
See details and how to joinNCT07166289
Phase 3Taking people
Biomarker-guided rTMS for Treatment Resistant Depression
Where
New York, Stanford
Age
22 years to 65 years
People
348
Run by
Weill Medical College of Cornell University
See details and how to joinNCT04041479