Heart failure trials in United States

In United States 387 Also abroad 1266

387 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
Where
Rochester
Age
18 years and over
People
800
Run by
Mayo Clinic
See details and how to joinNCT06195059
Phase 2Taking people
Rilonacept in Subjects With Cardiac Sarcoidosis
Where
Baltimore, Rochester
Age
18 years to 80 years
People
60
Run by
Mayo Clinic
See details and how to joinNCT06660732
No phaseTaking people
Exercise Cardiovascular Magnetic Resonance In Heart Failure With Preserved Ejection Fraction
Where
Rochester
Age
18 years to 80 years
People
400
Run by
Mayo Clinic
See details and how to joinNCT07401771
No phaseTaking people
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
Where
Anchorage, Aurora, Baltimore, Bethlehem, Boston, Charlotte, Charlottesville, Chicago, Cincinnati, Cleveland, Cooperstown, Dallas, Durham, Grand Rapids, Greenville, Hackensack, Hartford, Honolulu, Houston, Indianapolis, Iowa City, Jacksonville, Kansas City, La Jolla, Lancaster, Little Rock, Los Angeles, Madison, Milwaukee, Minneapolis, Morgantown, Morristown, Nashville, New York, Omaha, Palo Alto, Pittsburgh, Plano, Richmond, Roanoke, Roslyn, San Francisco, Seattle, St Louis, Temple, Tucson, Tupelo, Valhalla, Washington D.C., West Bloomfield, Wilkes-Barre
Age
18 years and over
People
1,700 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT05489705
No phaseTaking people
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
Where
Greensboro, Greenville, Miami, Omaha, Orlando, Palm Springs, Springfield
Age
18 years and over
People
1,200
Run by
Analog Device, Inc.
See details and how to joinNCT05650541
No phaseTaking people
Impella Reverse Remodeling in End-Stage Heart Failure
Where
New York
Age
18 years and over
People
50
Run by
Columbia University
See details and how to joinNCT06800716
No phaseEnrolling by invitation
Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Where
New Haven
Age
18 years and over
People
150
Run by
Yale University
See details and how to joinNCT07398950
Phase 3Taking people
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
Where
Acworth, Albany, Alexander City, Alhambra, Amarillo, Apex, Atlanta, Aurora, Austin, Baltimore, Beverly Hills, Biddeford, Birmingham, Bloomfield Hills, Bossier City, Bowie, Brooklyn, Camp Hill, Canton, Chambersburg, Charleston, Charlottesville, Chicago, Chula Vista, Cincinnati, Clearwater, Cleveland, Concord, Conroe, Conyers, Coral Gables, Corpus Christi, Covina, Crystal River, Dallas, Davenport, Dayton, Daytona Beach, Denison, Denver, Diamondhead, Doylestown, Duncanville, Durham, Elmer, El Paso, Eunice, Fairhope, Florida City, Forney, Fort Mill, Fort Worth, Fremont, Ft. Washington, Gainesville, Gilbert, Glendale, Golden, Granada Hills, Grand Rapids, Greeneville, Greenville, Hackettstown, Haddon Heights, Hammond, Hazel Crest, Honolulu, Houma, Houston, Huntington Beach, Huntington Park, Indianapolis, Iowa City, Irvine, Jackson, Jacksonville, Jersey City, Johns Creek, Kansas City, La Jolla, Lancaster, Lansing, Las Vegas, Lenoir, Lexington, Lincoln, Little Rock, Long Beach, Los Alamitos, Los Angeles, Louisville, Maitland, Manassas, Marion, Marshfield, Maumee, McAllen, McKinney, Meridian, Miami, Miami Beach, Miami Lakes, Milwaukee, Mobile, Morgantown, Murray, Newport News, New Port Richey, New York, Norfolk, Northridge, Ocala, Opelousas, Orlando, Orland Park, Ormond Beach, Owensboro, Palm Springs, Paramus, Peachtree, Pembroke Pines, Pensacola, Peoria, Philadelphia, Phoenix, Plano, Pomona, Portland, Raleigh, Rapid City, Richmond, Rochester, Rockville, Rosedale, Round Rock, Safety Harbor, San Antonio, San Diego, San Francisco, San Marcos, Santa Maria, Santa Rosa, Sarasota, Seattle, Sewell, Sherman, Shreveport, Somerset, Southfield, Statesville, St Louis, Stockton, Tacoma, Tampa, Tarzana, Temple, Thomasville, Thousand Oaks, Tucker, Valhalla, Vandalia, Van Nuys, Vienna, Virginia Gardens, Vista, Washington D.C., Wausau, West Hills, Wichita, Wilmington, Winchester, Winter Park, Ypsilanti
Age
18 years and over
People
5,610 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07567001 · EU 2025-523717-29-00
No phaseTaking people
Circulating Markers That Underlie the Transition From Compensated Hypertrophy to Heart Failure
Where
Farmington
Age
18 years and over
People
500
Run by
UConn Health
See details and how to joinNCT00762008
No phaseTaking people
Circulating Markers for Ischemic Heart Disease
Where
Farmington
Age
18 years and over
People
550
Run by
UConn Health
See details and how to joinNCT00762333
No phaseEnrolling by invitation
Pilot Study Exploring the Feasibility, Acceptability, and Impact of Medically Tailored Meals on Post-Discharge Recovery in Patients With Heart Failure
Where
Philadelphia
Age
18 years and over
People
85
Run by
University of Pennsylvania
See details and how to joinNCT07251894
No phaseTaking people
Alleviant ALLAY-HF Study
Where
Abilene, Ann Arbor, Asheville, Austin, Baltimore, Boston, Brighton, Charleston, Chicago, Cleveland, Colombia, Dallas, Decatur, Detroit, Durham, Edgewood, Gainesville, Germantown, Harrisburg, Hartford, Houma, Indianapolis, Jacksonville, Knoxville, Las Vegas, Long Beach, Milwaukee, Minneapolis, Naperville, Naples, New Orleans, New York, Oklahoma City, Orlando, Pensacola, Phoenix, Plano, Portland, Raleigh, Rapid City, Roslyn, Sacramento, San Diego, San Francisco, Santa Barbara, Scottsdale, Seattle, Springfield, St Louis, Stony Brook, Toledo, Tucson, Waco
Age
40 years and over
People
700 worldwide
Run by
Alleviant Medical, Inc.
See details and how to joinNCT05685303
No phaseTaking people
MediBeacon® Transdermal GFR System for the Evaluation of Kidney Function in Adults With Heart Failure
Where
New York
Age
18 years and over
People
15
Run by
MediBeacon
See details and how to joinNCT07349797
No phaseTaking people
Assessing Changes in Myocardial Tissue and Blood in Patients With Advanced Heart Disease
Where
Murray, Salt Lake City
Age
13 years and over
People
300
Run by
University of Utah
See details and how to joinNCT01099982
No phaseTaking people
LVAD Conditioning for Cardiac Recovery
Where
Salt Lake City
Age
18 years and over
People
100
Run by
STAVROS G DRAKOS
See details and how to joinNCT03238690
Phase 2Not yet taking people in United States
CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock
Where
Boston
Age
18 years to 80 years
People
30
Run by
Brigham and Women's Hospital
See details and how to joinNCT07461961
No phaseTaking people
Improving Self-Care of Caregivers of Adults in Homecare With Heart Failure and Cognitive Impairment
Where
New York
Age
18 years to 101 years
People
316
Run by
Visiting Nurse Service of New York
See details and how to joinNCT07220798
No phaseTaking people
Study of the Progression of Chronic Cardiovascular Conditions
Where
Chicago
Age
18 years and over
People
5,000
Run by
Prolaio
See details and how to joinNCT07420907
No phaseTaking people
Pedal Pump Clinical Trial on Edema V1
Where
Tulsa
Age
18 years and over
People
60
Run by
David McVay
See details and how to joinNCT07760363
No phaseTaking people
Neuromodulation of Inflammation and Endothelial Function
Where
Oklahoma City
Age
18 years to 85 years
People
158
Run by
University of Oklahoma
See details and how to joinNCT05230732
No phaseTaking people
OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
Where
Boston, Charleston, Dallas, Los Angeles, Nashville, Palo Alto
Age
18 years to 99 years
People
250
Run by
Northwestern University
See details and how to joinNCT06939751
Phase 4Taking people
Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction
Where
Charlottesville
Age
18 years to 90 years
People
192
Run by
University of Virginia
See details and how to joinNCT07178145
Phase 2Taking people
Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
Where
Dallas, Durham, New York, Palo Alto, Seattle
Age
0 years to 16 years
People
50
Run by
Stanford University
See details and how to joinNCT06080074
No phaseTaking people
Cardiovascular Multimodality Imaging Study
Where
The Bronx
Age
18 years and over
People
10,000
Run by
Montefiore Medical Center
See details and how to joinNCT06610019
Phase 2Not yet taking people in United States
Precision T1D Platform - New Therapies for Cardio-Renal Complications
Where
Ann Arbor, Portland
Age
18 years to 75 years
People
57
Run by
Oregon Health and Science University
See details and how to joinNCT07594145