Lupus (SLE) trials in United States

In United States 100 Also abroad 354

20 of 100 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Gonadotropin-releasing Hormone Agonist (GnRHa) in Ovarian Preservation in SLE Subjects Receiving Cyclophosphamide as Determined by Questionnaires
Where
Bethesda
Age
18 years to 120 years
People
100
Run by
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
See details and how to joinNCT05567198
No phaseTaking people
Deciphering the Genetic Architecture of Autoimmune Diseases
Where
Bethesda
Age
18 years to 115 years
People
300 worldwide
Run by
National Human Genome Research Institute (NHGRI)
See details and how to joinNCT06948110
No phaseTaking people
Electroencephalogram Recording in Patients With Systemic Lupus Erythematosus
Where
Manhasset
Age
18 years to 65 years
People
40
Run by
Northwell Health
See details and how to joinNCT06378736
No phaseTaking people
A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants
Where
Ann Arbor, Atlanta, Brooklyn, Charlotte, Corpus Christi, Denton, Durham, El Paso, Fort Lauderdale, Grand Blanc, Hollywood, Kalispell, La Jolla, La Palma, Los Angeles, Margate, Murfreesboro, Oklahoma City, Palm Beach Gardens, Philadelphia, Rockville, San Diego, Van Vleck, West Long Branch, Willowbrook
Age
16 years and over
People
223 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07175285
No phaseTaking people
Study of Systemic Lupus Erythematosus
Where
Bethesda
Age
3 years to 120 years
People
2,000
Run by
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
See details and how to joinNCT00001372
No phaseTaking people
Anifrolumab Pregnancy Study
Where
Cary
Age
18 years to 130 years
People
500
Run by
AstraZeneca
See details and how to joinNCT07049653
No phaseTaking people
Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users
Where
Wilmington
People
442
Run by
AstraZeneca
See details and how to joinNCT06659029
No phaseTaking people
Systemic Lupus Erythematosus in Gullah Health
Where
Charleston
Age
2 years and over
People
750
Run by
Medical University of South Carolina
See details and how to joinNCT00756769
No phaseTaking people
Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
Where
Washington D.C.
Age
5 years to 21 years
People
90
Run by
Children's National Research Institute
See details and how to joinNCT04833465
No phaseTaking people
Study to Assess Real-world Effectiveness of Belimumab for Treatment of Adults With LN
Where
Baltimore, Charlotte, Columbus, Hixson
Age
18 years and over
People
300 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06527872
No phaseTaking people
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
Where
Houston
Age
18 years and over
People
125
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04751396
No phaseTaking people
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
Where
Baltimore, Chicago, New York, Oklahoma City, Salt Lake City
Age
18 years to 45 years
People
700 worldwide
Run by
Hospital for Special Surgery, New York
See details and how to joinNCT00198068
No phaseTaking people
Lupus Landmark Study: A Prospective Registry and Biorepository
Where
Atlanta, Beverly Hills, Birmingham, Boston, Chapel Hill, Chicago, Cleveland, Dallas, Los Angeles, Manhasset, Miami, Nashville, New York, St Louis, Syracuse, Tucson, Washington D.C., Worcester
Age
18 years to 110 years
People
3,500 worldwide
Run by
Lupus Research Alliance
See details and how to joinNCT05934149
No phaseTaking people
Rheumatology Patient Registry and Biorepository
Where
New Haven
Age
18 years to 99 years
People
5,000
Run by
Yale University
See details and how to joinNCT04402086
Phase 2/3Taking people
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Where
Denver
Age
18 years and over
People
70 worldwide
Run by
Kyverna Therapeutics
See details and how to joinNCT07403188 · EU 2024-511198-31-00
No phaseTaking people
CorEvitas Systemic Lupus Erythematosus (SLE) Drug Safety and Effectiveness Registry
Where
Waltham
Age
18 years and over
People
1,000
Run by
CorEvitas
See details and how to joinNCT06804057
No phaseTaking people
Research Accelerated by You Lupus Registry
Where
Washington D.C.
People
10,000
Run by
Lupus Foundation of America
See details and how to joinNCT06927219
No phaseTaking people
Duke Lupus Registry
Where
Durham
Age
18 years and over
People
1,000
Run by
Duke University
See details and how to joinNCT00512694
No phaseTaking people
Maternal Autoimmune Disease Research Alliance (MADRA) Registry
Where
Durham
People
1,000
Run by
Duke University
See details and how to joinNCT03276923
No phaseTaking people
Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)
Where
New York
Age
18 years and over
People
2,000
Run by
The Rogosin Institute
See details and how to joinNCT01802034