Lupus (SLE) trials in United States

In United States 100 Also abroad 354

100 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Enrolling by invitation
Electromagnetic Immunotherapy Mapping and Cytokine Forecasting Study (QSIT)
Where
New York
People
120
Run by
Truway Health, Inc.
See details and how to joinNCT07221565
Phase 2Taking people
2-HOBA in Systemic Lupus Erythematosus
Where
Nashville
Age
18 years and over
People
42
Run by
Vanderbilt University Medical Center
See details and how to joinNCT07225543
No phaseTaking people
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
Where
Houston
Age
18 years and over
People
125
Run by
M.D. Anderson Cancer Center
See details and how to joinNCT04751396
No phaseTaking people
Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
Where
Baltimore, Chicago, New York, Oklahoma City, Salt Lake City
Age
18 years to 45 years
People
700 worldwide
Run by
Hospital for Special Surgery, New York
See details and how to joinNCT00198068
Phase 1Taking people
Alnuctamab for Refractory SLE (LATTE Study)
Where
New York
Age
18 years to 60 years
People
21
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07219563
No phaseTaking people
Lupus Landmark Study: A Prospective Registry and Biorepository
Where
Atlanta, Beverly Hills, Birmingham, Boston, Chapel Hill, Chicago, Cleveland, Dallas, Los Angeles, Manhasset, Miami, Nashville, New York, St Louis, Syracuse, Tucson, Washington D.C., Worcester
Age
18 years to 110 years
People
3,500 worldwide
Run by
Lupus Research Alliance
See details and how to joinNCT05934149
Phase 1Taking people
A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE)
Where
Allen, San Antonio
Age
18 years to 65 years
People
30 worldwide
Run by
Climb Bio, Inc.
See details and how to joinNCT07011043
Phase 1Enrolling by invitation
A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease
Where
Buffalo, Redwood City
Age
18 years to 80 years
People
180
Run by
Adicet Therapeutics
See details and how to joinNCT06375993
No phaseTaking people
Rheumatology Patient Registry and Biorepository
Where
New Haven
Age
18 years to 99 years
People
5,000
Run by
Yale University
See details and how to joinNCT04402086
Phase 2/3Taking people
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Where
Denver
Age
18 years and over
People
70 worldwide
Run by
Kyverna Therapeutics
See details and how to joinNCT07403188 · EU 2024-511198-31-00
No phaseTaking people
CorEvitas Systemic Lupus Erythematosus (SLE) Drug Safety and Effectiveness Registry
Where
Waltham
Age
18 years and over
People
1,000
Run by
CorEvitas
See details and how to joinNCT06804057
No phaseTaking people
Research Accelerated by You Lupus Registry
Where
Washington D.C.
People
10,000
Run by
Lupus Foundation of America
See details and how to joinNCT06927219
No phaseTaking people
Duke Lupus Registry
Where
Durham
Age
18 years and over
People
1,000
Run by
Duke University
See details and how to joinNCT00512694
No phaseTaking people
Maternal Autoimmune Disease Research Alliance (MADRA) Registry
Where
Durham
People
1,000
Run by
Duke University
See details and how to joinNCT03276923
No phaseTaking people
Helping Lupus Patients Manage Fibromyalgia Symptoms Through Emotional Awareness and Expression Therapy (EAET)
Where
Salt Lake City
Age
18 years to 65 years
People
30
Run by
University of Utah
See details and how to joinNCT07282392
Phase 1Taking people
REACT-01: Reversing Autoimmunity Through Cell Therapy
Where
Seattle
Age
2 years to 30 years
People
12
Run by
Seattle Children's Hospital
See details and how to joinNCT06465147
Early phase 1Taking people
Safety and Efficacy of ONT01 in Lupus
Where
New York
Age
18 years and over
People
61
Run by
Hospital for Special Surgery, New York
See details and how to joinNCT07107659
Phase 4Taking people
Safety and Efficacy of Combination Belimumab and Voclosporin in the Treatment of Proliferative Forms of Lupus Glomerulopathy: Synergy Trial
Where
Atlanta, Columbus, Fort Worth, Glendale, Lawrenceville, Oklahoma City
Age
18 years to 80 years
People
30
Run by
NephroNet, Inc.
See details and how to joinNCT07225387
No phaseTaking people
Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus
Where
Birmingham, Cincinnati, Grand Rapids, New Orleans, Seattle, The Bronx
Age
12 years to 22 years
People
175 worldwide
Run by
Michigan State University
See details and how to joinNCT06232304
Phase 2Taking people
Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases
Where
Philadelphia
Age
8 years to 25 years
People
20
Run by
Stephan Grupp MD PhD
See details and how to joinNCT05029336
Phase 1Taking people
UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients
Where
Charleston
Age
18 years to 75 years
People
10
Run by
LiveKidney.Bio
See details and how to joinNCT06737380
Phase 1Taking people
BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus
Where
Columbus
Age
18 years to 65 years
People
18
Run by
Luminary Therapeutics
See details and how to joinNCT06340750
No phaseTaking people
Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)
Where
New York
Age
18 years and over
People
2,000
Run by
The Rogosin Institute
See details and how to joinNCT01802034
Phase 1Taking people
Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases.
Where
Plantation
Age
18 years and over
People
30
Run by
IRIS Research and Development, LLC
See details and how to joinNCT06581562
Phase 1/2Taking people
Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor
Where
Palo Alto
Age
1 year to 30 years
People
12
Run by
Alice Bertaina
See details and how to joinNCT05508009